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Volumn 66, Issue 6, 2014, Pages 1405-1413

Review: Is there a window of opportunity for treatment of systemic juvenile idiopathic arthritis?

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CANAKINUMAB; CORTICOSTEROID; CRYOPYRIN; D DIMER; FC RECEPTOR; FERRITIN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 6; PROTEIN KINASE ZAP 70; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RILONACEPT; TOCILIZUMAB;

EID: 84901606673     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.38615     Document Type: Review
Times cited : (159)

References (85)
  • 1
    • 0242579549 scopus 로고    scopus 로고
    • The -174G allele of the interleukin-6 gene confers susceptibility to systemic arthritis in children: A multicenter study using simplex and multiplex juvenile idiopathic arthritis families
    • et al.
    • Ogilvie EM, Fife MS, Thompson SD, Twine N, Tsoras M, Moroldo M, et al. The -174G allele of the interleukin-6 gene confers susceptibility to systemic arthritis in children: a multicenter study using simplex and multiplex juvenile idiopathic arthritis families. Arthritis Rheum 2003; 48: 3202-6.
    • (2003) Arthritis Rheum , vol.48 , pp. 3202-3206
    • Ogilvie, E.M.1    Fife, M.S.2    Thompson, S.D.3    Twine, N.4    Tsoras, M.5    Moroldo, M.6
  • 2
    • 39549087921 scopus 로고    scopus 로고
    • Evaluation of the presentation of systemic onset juvenile rheumatoid arthritis: Data from the Pennsylvania Systemic Onset Juvenile Arthritis Registry (PASOJAR)
    • et al.
    • Behrens EM, Beukelman T, Gallo L, Spangler J, Rosenkranz M, Arkachaisri T, et al. Evaluation of the presentation of systemic onset juvenile rheumatoid arthritis: data from the Pennsylvania Systemic Onset Juvenile Arthritis Registry (PASOJAR). J Rheumatol 2008; 35: 343-8.
    • (2008) J Rheumatol , vol.35 , pp. 343-348
    • Behrens, E.M.1    Beukelman, T.2    Gallo, L.3    Spangler, J.4    Rosenkranz, M.5    Arkachaisri, T.6
  • 3
    • 84874862892 scopus 로고    scopus 로고
    • Patients with very early-onset systemic juvenile idiopathic arthritis exhibit more inflammatory features and a worse outcome
    • Russo RA, Katsicas MM,. Patients with very early-onset systemic juvenile idiopathic arthritis exhibit more inflammatory features and a worse outcome. J Rheumatol 2013; 40: 329-34.
    • (2013) J Rheumatol , vol.40 , pp. 329-334
    • Russo, R.A.1    Katsicas, M.M.2
  • 4
    • 84860522672 scopus 로고    scopus 로고
    • Making sense of the cytokine storm: A conceptual framework for understanding, diagnosing, and treating hemophagocytic syndromes
    • Canna SW, Behrens EM,. Making sense of the cytokine storm: a conceptual framework for understanding, diagnosing, and treating hemophagocytic syndromes. Pediatr Clin North Am 2012; 59: 329-44.
    • (2012) Pediatr Clin North Am , vol.59 , pp. 329-344
    • Canna, S.W.1    Behrens, E.M.2
  • 5
    • 0033962724 scopus 로고    scopus 로고
    • Systemic onset juvenile idiopathic arthritis: A retrospective study of 80 consecutive patients followed for 10 years
    • Lomater C, Gerloni V, Gattinara M, Mazzotti J, Cimaz R, Fantini F,. Systemic onset juvenile idiopathic arthritis: a retrospective study of 80 consecutive patients followed for 10 years. J Rheumatol 2000; 27: 491-6.
    • (2000) J Rheumatol , vol.27 , pp. 491-496
    • Lomater, C.1    Gerloni, V.2    Gattinara, M.3    Mazzotti, J.4    Cimaz, R.5    Fantini, F.6
  • 6
    • 0347997280 scopus 로고    scopus 로고
    • Remission in juvenile chronic arthritis: A cohort study of 683 consecutive cases with a mean 10 year followup
    • Fantini F, Gerloni V, Gattinara M, Cimaz R, Arnoldi C, Lupi E,. Remission in juvenile chronic arthritis: a cohort study of 683 consecutive cases with a mean 10 year followup. J Rheumatol 2003; 30: 579-84.
    • (2003) J Rheumatol , vol.30 , pp. 579-584
    • Fantini, F.1    Gerloni, V.2    Gattinara, M.3    Cimaz, R.4    Arnoldi, C.5    Lupi, E.6
  • 7
    • 0033763981 scopus 로고    scopus 로고
    • Early predictors of poor functional outcome in systemic-onset juvenile rheumatoid arthritis: A multicenter cohort study
    • et al.
    • Spiegel LR, Schneider R, Lang BA, Birdi N, Silverman ED, Laxer RM, et al. Early predictors of poor functional outcome in systemic-onset juvenile rheumatoid arthritis: a multicenter cohort study. Arthritis Rheum 2000; 43: 2402-9.
    • (2000) Arthritis Rheum , vol.43 , pp. 2402-2409
    • Spiegel, L.R.1    Schneider, R.2    Lang, B.A.3    Birdi, N.4    Silverman, E.D.5    Laxer, R.M.6
  • 8
    • 33646477692 scopus 로고    scopus 로고
    • Predictors of disease course and remission in systemic juvenile idiopathic arthritis: Significance of early clinical and laboratory features
    • Singh-Grewal D, Schneider R, Bayer N, Feldman BM,. Predictors of disease course and remission in systemic juvenile idiopathic arthritis: significance of early clinical and laboratory features. Arthritis Rheum 2006; 54: 1595-601.
    • (2006) Arthritis Rheum , vol.54 , pp. 1595-1601
    • Singh-Grewal, D.1    Schneider, R.2    Bayer, N.3    Feldman, B.M.4
  • 9
    • 33645953936 scopus 로고    scopus 로고
    • Care of the adult with juvenile rheumatoid arthritis
    • Nigrovic PA, White PH,. Care of the adult with juvenile rheumatoid arthritis. Arthritis Rheum 2006; 55: 208-16.
    • (2006) Arthritis Rheum , vol.55 , pp. 208-216
    • Nigrovic, P.A.1    White, P.H.2
  • 11
    • 73649098325 scopus 로고    scopus 로고
    • Adult outcomes of patients with juvenile idiopathic arthritis
    • Minden K,. Adult outcomes of patients with juvenile idiopathic arthritis. Horm Res 2009; 72 Suppl 1: 20-5.
    • (2009) Horm Res , vol.72 , Issue.SUPPL. 1 , pp. 20-25
    • Minden, K.1
  • 12
    • 79551654446 scopus 로고    scopus 로고
    • Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: Report of forty-six patients from an international multicenter series
    • et al.
    • Nigrovic PA, Mannion M, Prince FH, Zeft A, Rabinovich CE, van Rossum MA, et al. Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: report of forty-six patients from an international multicenter series. Arthritis Rheum 2011; 63: 545-55.
    • (2011) Arthritis Rheum , vol.63 , pp. 545-555
    • Nigrovic, P.A.1    Mannion, M.2    Prince, F.H.3    Zeft, A.4    Rabinovich, C.E.5    Van Rossum, M.A.6
  • 13
    • 77950400448 scopus 로고    scopus 로고
    • Early outcomes and improvement of patients with juvenile idiopathic arthritis enrolled in a Canadian multicenter inception cohort
    • et al.
    • Oen K, Duffy CM, Tse SM, Ramsey S, Ellsworth J, Chedeville G, et al. Early outcomes and improvement of patients with juvenile idiopathic arthritis enrolled in a Canadian multicenter inception cohort. Arthritis Care Res (Hoboken) 2010; 62: 527-36.
    • (2010) Arthritis Care Res (Hoboken) , vol.62 , pp. 527-536
    • Oen, K.1    Duffy, C.M.2    Tse, S.M.3    Ramsey, S.4    Ellsworth, J.5    Chedeville, G.6
  • 14
    • 0026512048 scopus 로고
    • Prognostic indicators of joint destruction in systemic-onset juvenile rheumatoid arthritis
    • et al.
    • Schneider R, Lang BA, Reilly BJ, Laxer RM, Silverman ED, Ibanez D, et al. Prognostic indicators of joint destruction in systemic-onset juvenile rheumatoid arthritis. J Pediatr 1992; 120: 200-5.
    • (1992) J Pediatr , vol.120 , pp. 200-205
    • Schneider, R.1    Lang, B.A.2    Reilly, B.J.3    Laxer, R.M.4    Silverman, E.D.5    Ibanez, D.6
  • 15
    • 33750992176 scopus 로고    scopus 로고
    • Candidate early predictors for progression to joint damage in systemic juvenile idiopathic arthritis
    • et al.
    • Sandborg C, Holmes TH, Lee T, Biederman K, Bloch DA, Emery H, et al. Candidate early predictors for progression to joint damage in systemic juvenile idiopathic arthritis. J Rheumatol 2006; 33: 2322-9.
    • (2006) J Rheumatol , vol.33 , pp. 2322-2329
    • Sandborg, C.1    Holmes, T.H.2    Lee, T.3    Biederman, K.4    Bloch, D.A.5    Emery, H.6
  • 16
    • 44949241656 scopus 로고    scopus 로고
    • Global damage in systemic juvenile idiopathic arthritis: Preliminary early predictors
    • Russo RA, Katsicas MM,. Global damage in systemic juvenile idiopathic arthritis: preliminary early predictors. J Rheumatol 2008; 35: 1151-6.
    • (2008) J Rheumatol , vol.35 , pp. 1151-1156
    • Russo, R.A.1    Katsicas, M.M.2
  • 17
    • 64849083343 scopus 로고    scopus 로고
    • Persistent elevation of fibrin D-dimer predicts longterm outcome in systemic juvenile idiopathic arthritis
    • Bloom BJ, Alario AJ, Miller LC,. Persistent elevation of fibrin D-dimer predicts longterm outcome in systemic juvenile idiopathic arthritis. J Rheumatol 2009; 36: 422-6.
    • (2009) J Rheumatol , vol.36 , pp. 422-426
    • Bloom, B.J.1    Alario, A.J.2    Miller, L.C.3
  • 18
    • 5044223401 scopus 로고    scopus 로고
    • Effective use of the recombinant interleukin 1 receptor antagonist anakinra in therapy resistant systemic onset juvenile rheumatoid arthritis
    • Verbsky JW, White AJ,. Effective use of the recombinant interleukin 1 receptor antagonist anakinra in therapy resistant systemic onset juvenile rheumatoid arthritis. J Rheumatol 2004; 31: 2071-5.
    • (2004) J Rheumatol , vol.31 , pp. 2071-2075
    • Verbsky, J.W.1    White, A.J.2
  • 19
    • 18644385243 scopus 로고    scopus 로고
    • Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade
    • Pascual V, Allantaz F, Arce E, Punaro M, Banchereau J,. Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade. J Exp Med 2005; 201: 1479-86.
    • (2005) J Exp Med , vol.201 , pp. 1479-1486
    • Pascual, V.1    Allantaz, F.2    Arce, E.3    Punaro, M.4    Banchereau, J.5
  • 20
    • 43949116263 scopus 로고    scopus 로고
    • The pattern of response to anti-interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis
    • et al.
    • Gattorno M, Piccini A, Lasiglie D, Tassi S, Brisca G, Carta S, et al. The pattern of response to anti-interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis. Arthritis Rheum 2008; 58: 1505-15.
    • (2008) Arthritis Rheum , vol.58 , pp. 1505-1515
    • Gattorno, M.1    Piccini, A.2    Lasiglie, D.3    Tassi, S.4    Brisca, G.5    Carta, S.6
  • 21
    • 39549109506 scopus 로고    scopus 로고
    • Interleukin-1 receptor antagonist (anakinra) treatment in patients with systemic-onset juvenile idiopathic arthritis or adult onset Still disease: Preliminary experience in France
    • et al.
    • Lequerre T, Quartier P, Rosellini D, Alaoui F, De Bandt M, Mejjad O, et al. Interleukin-1 receptor antagonist (anakinra) treatment in patients with systemic-onset juvenile idiopathic arthritis or adult onset Still disease: preliminary experience in France. Ann Rheum Dis 2008; 67: 302-8.
    • (2008) Ann Rheum Dis , vol.67 , pp. 302-308
    • Lequerre, T.1    Quartier, P.2    Rosellini, D.3    Alaoui, F.4    De Bandt, M.5    Mejjad, O.6
  • 24
    • 79953323633 scopus 로고    scopus 로고
    • A multicentre, randomised, double-blind, placebo-controlled trial with the interleukin-1 receptor antagonist anakinra in patients with systemic-onset juvenile idiopathic arthritis (ANAJIS trial)
    • et al.
    • Quartier P, Allantaz F, Cimaz R, Pillet P, Messiaen C, Bardin C, et al. A multicentre, randomised, double-blind, placebo-controlled trial with the interleukin-1 receptor antagonist anakinra in patients with systemic-onset juvenile idiopathic arthritis (ANAJIS trial). Ann Rheum Dis 2011; 70: 747-54.
    • (2011) Ann Rheum Dis , vol.70 , pp. 747-754
    • Quartier, P.1    Allantaz, F.2    Cimaz, R.3    Pillet, P.4    Messiaen, C.5    Bardin, C.6
  • 25
    • 84883233255 scopus 로고    scopus 로고
    • Long-term safety and efficacy of rilonacept in patients with systemic juvenile idiopathic arthritis
    • et al.
    • Lovell DJ, Giannini EH, Reiff AO, Kimura Y, Li S, Hashkes PJ, et al. Long-term safety and efficacy of rilonacept in patients with systemic juvenile idiopathic arthritis. Arthritis Rheum 2013; 65: 2486-96.
    • (2013) Arthritis Rheum , vol.65 , pp. 2486-2496
    • Lovell, D.J.1    Giannini, E.H.2    Reiff, A.O.3    Kimura, Y.4    Li, S.5    Hashkes, P.J.6
  • 26
    • 84899717442 scopus 로고    scopus 로고
    • The randomized placebo phase study of rilonacept in the treatment of systemic juvenile idiopathic arthritis
    • [abstract].
    • Ilowite NT, Prather K, Lokhnygina Y, Schanberg LE, Elder M, Milojevic D, et al. The randomized placebo phase study of rilonacept in the treatment of systemic juvenile idiopathic arthritis [abstract]. Arthritis Rheum 2013; 65 Suppl: S757-8.
    • (2013) Arthritis Rheum , vol.65 , Issue.SUPPL.
    • Ilowite, N.T.1    Prather, K.2    Lokhnygina, Y.3    Schanberg, L.E.4    Elder, M.5    Et Al., M.D.6
  • 27
    • 84856370186 scopus 로고    scopus 로고
    • A phase II, multicenter, open-label study evaluating dosing and preliminary safety and efficacy of canakinumab in systemic juvenile idiopathic arthritis with active systemic features
    • et al, for the Paediatric Rheumatology International Clinical Trials Organisation.
    • Ruperto N, Quartier P, Wulffraat N, Woo P, Ravelli A, Mouy R, et al, for the Paediatric Rheumatology International Clinical Trials Organisation. A phase II, multicenter, open-label study evaluating dosing and preliminary safety and efficacy of canakinumab in systemic juvenile idiopathic arthritis with active systemic features. Arthritis Rheum 2012; 64: 557-67.
    • (2012) Arthritis Rheum , vol.64 , pp. 557-567
    • Ruperto, N.1    Quartier, P.2    Wulffraat, N.3    Woo, P.4    Ravelli, A.5    Mouy, R.6
  • 29
    • 84890917584 scopus 로고    scopus 로고
    • Biologic treatments for adult-onset Still's disease
    • Al-Homood IA,. Biologic treatments for adult-onset Still's disease. Rheumatology (Oxford) 2014; 53: 32-8.
    • (2014) Rheumatology (Oxford) , vol.53 , pp. 32-38
    • Al-Homood, I.A.1
  • 30
    • 84872189654 scopus 로고    scopus 로고
    • Anakinra: A safe and effective first-line treatment in systemic onset juvenile idiopathic arthritis (SoJIA)
    • Hedrich CM, Bruck N, Fiebig B, Gahr M,. Anakinra: a safe and effective first-line treatment in systemic onset juvenile idiopathic arthritis (SoJIA). Rheumatol Int 2012; 32: 3525-30.
    • (2012) Rheumatol Int , vol.32 , pp. 3525-3530
    • Hedrich, C.M.1    Bruck, N.2    Fiebig, B.3    Gahr, M.4
  • 31
    • 84898640609 scopus 로고    scopus 로고
    • Effectiveness of first-line treatment with recombinant interleukin-1 receptor antagonist in steroid-naive patients with new-onset systemic juvenile idiopathic arthritis: Results of a prospective cohort study
    • et al.
    • Vastert SJ, de Jager W, Noordman BJ, Holzinger D, Kuis W, Prakken BJ, et al. Effectiveness of first-line treatment with recombinant interleukin-1 receptor antagonist in steroid-naive patients with new-onset systemic juvenile idiopathic arthritis: results of a prospective cohort study. Arthritis Rheumatol 2014; 66: 1034-43.
    • (2014) Arthritis Rheumatol , vol.66 , pp. 1034-1043
    • Vastert, S.J.1    De Jager, W.2    Noordman, B.J.3    Holzinger, D.4    Kuis, W.5    Prakken, B.J.6
  • 32
    • 84901622546 scopus 로고    scopus 로고
    • Efficacy of canakinumab in the treatment of systemic juvenile idiopathic arthritis: A 12-week pooled post-hoc analysis
    • et al, and PRINTO/PRCSG. [abstract].
    • Quartier P, Brunner H, Constantin T, Padeh S, Calvo I, Erguven M, et al, and PRINTO/PRCSG. Efficacy of canakinumab in the treatment of systemic juvenile idiopathic arthritis: a 12-week pooled post-hoc analysis [abstract]. Pediatr Rheumatol 2013; 11 Suppl 2: P169.
    • (2013) Pediatr Rheumatol , vol.11 , Issue.SUPPL. 2
    • Quartier, P.1    Brunner, H.2    Constantin, T.3    Padeh, S.4    Calvo, I.5    Erguven, M.6
  • 33
    • 33746876396 scopus 로고    scopus 로고
    • Neonatal-onset multisystem inflammatory disease responsive to interleukin-1β inhibition
    • et al.
    • Goldbach-Mansky R, Dailey NJ, Canna SW, Gelabert A, Jones J, Rubin BI, et al. Neonatal-onset multisystem inflammatory disease responsive to interleukin-1β inhibition. N Engl J Med 2006; 355: 581-92.
    • (2006) N Engl J Med , vol.355 , pp. 581-592
    • Goldbach-Mansky, R.1    Dailey, N.J.2    Canna, S.W.3    Gelabert, A.4    Jones, J.5    Rubin, B.I.6
  • 34
    • 84863228835 scopus 로고    scopus 로고
    • Sustained response and prevention of damage progression in patients with neonatal-onset multisystem inflammatory disease treated with anakinra: A cohort study to determine three- and five-year outcomes
    • et al.
    • Sibley CH, Plass N, Snow J, Wiggs EA, Brewer CC, King KA, et al. Sustained response and prevention of damage progression in patients with neonatal-onset multisystem inflammatory disease treated with anakinra: a cohort study to determine three- and five-year outcomes. Arthritis Rheum 2012; 64: 2375-86.
    • (2012) Arthritis Rheum , vol.64 , pp. 2375-2386
    • Sibley, C.H.1    Plass, N.2    Snow, J.3    Wiggs, E.A.4    Brewer, C.C.5    King, K.A.6
  • 36
    • 58149181586 scopus 로고    scopus 로고
    • Anakinra in the treatment of polyarticular-course juvenile rheumatoid arthritis: Safety and preliminary efficacy results of a randomized multicenter study
    • et al.
    • Ilowite N, Porras O, Reiff A, Rudge S, Punaro M, Martin A, et al. Anakinra in the treatment of polyarticular-course juvenile rheumatoid arthritis: safety and preliminary efficacy results of a randomized multicenter study. Clin Rheumatol 2009; 28: 129-37.
    • (2009) Clin Rheumatol , vol.28 , pp. 129-137
    • Ilowite, N.1    Porras, O.2    Reiff, A.3    Rudge, S.4    Punaro, M.5    Martin, A.6
  • 37
    • 84883255531 scopus 로고    scopus 로고
    • Anakinra pharmacokinetics in children and adolescents with systemic-onset juvenile idiopathic arthritis and autoinflammatory syndromes
    • et al.
    • Urien S, Bardin C, Bader-Meunier B, Mouy R, Compeyrot-Lacassagne S, Foissac F, et al. Anakinra pharmacokinetics in children and adolescents with systemic-onset juvenile idiopathic arthritis and autoinflammatory syndromes. BMC Pharmacol Toxicol 2013; 14: 40.
    • (2013) BMC Pharmacol Toxicol , vol.14 , pp. 40
    • Urien, S.1    Bardin, C.2    Bader-Meunier, B.3    Mouy, R.4    Compeyrot-Lacassagne, S.5    Foissac, F.6
  • 38
    • 84863428204 scopus 로고    scopus 로고
    • Consensus treatment plans for new-onset systemic juvenile idiopathic arthritis
    • et al, on behalf of the Juvenile Idiopathic Arthritis Disease-Specific Research Committee of the Childhood Arthritis and Rheumatology Research Alliance.
    • DeWitt EM, Kimura Y, Beukelman T, Nigrovic PA, Onel K, Prahalad S, et al, on behalf of the Juvenile Idiopathic Arthritis Disease-Specific Research Committee of the Childhood Arthritis and Rheumatology Research Alliance. Consensus treatment plans for new-onset systemic juvenile idiopathic arthritis. Arthritis Care Res (Hoboken) 2012; 64: 1001-10.
    • (2012) Arthritis Care Res (Hoboken) , vol.64 , pp. 1001-1010
    • Dewitt, E.M.1    Kimura, Y.2    Beukelman, T.3    Nigrovic, P.A.4    Onel, K.5    Prahalad, S.6
  • 39
    • 84885103190 scopus 로고    scopus 로고
    • 2013 update of the 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: Recommendations for the medical therapy of children with systemic juvenile idiopathic arthritis and tuberculosis screening among children receiving biologic medications
    • et al.
    • Ringold S, Weiss PF, Beukelman T, DeWitt EM, Ilowite NT, Kimura Y, et al. 2013 update of the 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: recommendations for the medical therapy of children with systemic juvenile idiopathic arthritis and tuberculosis screening among children receiving biologic medications. Arthritis Rheum 2013; 65: 2499-512.
    • (2013) Arthritis Rheum , vol.65 , pp. 2499-2512
    • Ringold, S.1    Weiss, P.F.2    Beukelman, T.3    Dewitt, E.M.4    Ilowite, N.T.5    Kimura, Y.6
  • 40
    • 79959963298 scopus 로고    scopus 로고
    • Pathogenesis of systemic juvenile idiopathic arthritis: Some answers, more questions
    • Mellins ED, Macaubas C, Grom AA,. Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions. Nat Rev Rheumatol 2011; 7: 416-26.
    • (2011) Nat Rev Rheumatol , vol.7 , pp. 416-426
    • Mellins, E.D.1    Macaubas, C.2    Grom, A.A.3
  • 41
    • 0026014522 scopus 로고
    • Correlation of serum interleukin-6 levels with joint involvement and thrombocytosis in systemic juvenile rheumatoid arthritis
    • De Benedetti F, Massa M, Robbioni P, Ravelli A, Burgio GR, Martini A,. Correlation of serum interleukin-6 levels with joint involvement and thrombocytosis in systemic juvenile rheumatoid arthritis. Arthritis Rheum 1991; 34: 1158-63.
    • (1991) Arthritis Rheum , vol.34 , pp. 1158-1163
    • De Benedetti, F.1    Massa, M.2    Robbioni, P.3    Ravelli, A.4    Burgio, G.R.5    Martini, A.6
  • 42
    • 34447523762 scopus 로고    scopus 로고
    • Specific gene expression profiles in systemic juvenile idiopathic arthritis
    • Ogilvie EM, Khan A, Hubank M, Kellam P, Woo P,. Specific gene expression profiles in systemic juvenile idiopathic arthritis. Arthritis Rheum 2007; 56: 1954-65.
    • (2007) Arthritis Rheum , vol.56 , pp. 1954-1965
    • Ogilvie, E.M.1    Khan, A.2    Hubank, M.3    Kellam, P.4    Woo, P.5
  • 43
    • 40749152243 scopus 로고    scopus 로고
    • Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: A randomised, double-blind, placebo-controlled, withdrawal phase III trial
    • et al.
    • Yokota S, Imagawa T, Mori M, Miyamae T, Aihara Y, Takei S, et al. Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal phase III trial. Lancet 2008; 371: 998-1006.
    • (2008) Lancet , vol.371 , pp. 998-1006
    • Yokota, S.1    Imagawa, T.2    Mori, M.3    Miyamae, T.4    Aihara, Y.5    Takei, S.6
  • 45
    • 84859780892 scopus 로고    scopus 로고
    • Successful treatment of adult-onset Still's disease with tocilizumab monotherapy: Two case reports and literature review
    • et al.
    • Sakai R, Nagasawa H, Nishi E, Okuyama A, Takei H, Kurasawa T, et al. Successful treatment of adult-onset Still's disease with tocilizumab monotherapy: two case reports and literature review. Clin Rheumatol 2012; 31: 569-74.
    • (2012) Clin Rheumatol , vol.31 , pp. 569-574
    • Sakai, R.1    Nagasawa, H.2    Nishi, E.3    Okuyama, A.4    Takei, H.5    Kurasawa, T.6
  • 46
    • 77950627242 scopus 로고    scopus 로고
    • IL-1 pathways in inflammation and human diseases
    • Gabay C, Lamacchia C, Palmer G,. IL-1 pathways in inflammation and human diseases. Nat Rev Rheumatol 2010; 6: 232-41.
    • (2010) Nat Rev Rheumatol , vol.6 , pp. 232-241
    • Gabay, C.1    Lamacchia, C.2    Palmer, G.3
  • 47
    • 79953813107 scopus 로고    scopus 로고
    • Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
    • Dinarello CA,. Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood 2011; 117: 3720-32.
    • (2011) Blood , vol.117 , pp. 3720-3732
    • Dinarello, C.A.1
  • 48
    • 75749099362 scopus 로고    scopus 로고
    • Excessive interleukin-1 signaling determines the development of Th1 and Th17 responses in chronic inflammation
    • [editorial].
    • Joosten LA,. Excessive interleukin-1 signaling determines the development of Th1 and Th17 responses in chronic inflammation [editorial]. Arthritis Rheum 2010; 62: 320-2.
    • (2010) Arthritis Rheum , vol.62 , pp. 320-322
    • Joosten, L.A.1
  • 49
    • 84888871863 scopus 로고    scopus 로고
    • The plasticity of human Treg and Th17 cells and its role in autoimmunity
    • Kleinewietfeld M, Hafler DA,. The plasticity of human Treg and Th17 cells and its role in autoimmunity. Semin Immunol 2013; 25: 305-12.
    • (2013) Semin Immunol , vol.25 , pp. 305-312
    • Kleinewietfeld, M.1    Hafler, D.A.2
  • 51
    • 78149236392 scopus 로고    scopus 로고
    • Interleukin-1β and interleukin-6 in arthritis animal models: Roles in the early phase of transition from acute to chronic inflammation and relevance for human rheumatoid arthritis
    • Ferraccioli G, Bracci-Laudiero L, Alivernini S, Gremese E, Tolusso B, De Benedetti F,. Interleukin-1β and interleukin-6 in arthritis animal models: roles in the early phase of transition from acute to chronic inflammation and relevance for human rheumatoid arthritis. Mol Med 2010; 16: 552-7.
    • (2010) Mol Med , vol.16 , pp. 552-557
    • Ferraccioli, G.1    Bracci-Laudiero, L.2    Alivernini, S.3    Gremese, E.4    Tolusso, B.5    De Benedetti, F.6
  • 52
    • 1142274317 scopus 로고    scopus 로고
    • The role of antibodies in mouse models of rheumatoid arthritis, and relevance to human disease
    • Monach PA, Benoist C, Mathis D,. The role of antibodies in mouse models of rheumatoid arthritis, and relevance to human disease. Adv Immunol 2004; 82: 217-48.
    • (2004) Adv Immunol , vol.82 , pp. 217-248
    • Monach, P.A.1    Benoist, C.2    Mathis, D.3
  • 53
    • 0345414139 scopus 로고    scopus 로고
    • Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
    • et al.
    • Sakaguchi N, Takahashi T, Hata H, Nomura T, Tagami T, Yamazaki S, et al. Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice. Nature 2003; 426: 454-60.
    • (2003) Nature , vol.426 , pp. 454-460
    • Sakaguchi, N.1    Takahashi, T.2    Hata, H.3    Nomura, T.4    Tagami, T.5    Yamazaki, S.6
  • 54
    • 0034677123 scopus 로고    scopus 로고
    • Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice
    • et al.
    • Horai R, Saijo S, Tanioka H, Nakae S, Sudo K, Okahara A, et al. Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice. J Exp Med 2000; 191: 313-20.
    • (2000) J Exp Med , vol.191 , pp. 313-320
    • Horai, R.1    Saijo, S.2    Tanioka, H.3    Nakae, S.4    Sudo, K.5    Okahara, A.6
  • 55
    • 0036681846 scopus 로고    scopus 로고
    • The importance of IL-1β and TNF-α, and the noninvolvement of IL-6, in the development of monoclonal antibody-induced arthritis
    • Kagari T, Doi H, Shimozato T,. The importance of IL-1β and TNF-α, and the noninvolvement of IL-6, in the development of monoclonal antibody-induced arthritis. J Immunol 2002; 169: 1459-66.
    • (2002) J Immunol , vol.169 , pp. 1459-1466
    • Kagari, T.1    Doi, H.2    Shimozato, T.3
  • 56
    • 0036645277 scopus 로고    scopus 로고
    • Critical roles for interleukin 1 and tumor necrosis factor α in antibody-induced arthritis
    • et al.
    • Ji H, Pettit A, Ohmura K, Ortiz-Lopez A, Duchatelle V, Degott C, et al. Critical roles for interleukin 1 and tumor necrosis factor α in antibody-induced arthritis. J Exp Med 2002; 196: 77-85.
    • (2002) J Exp Med , vol.196 , pp. 77-85
    • Ji, H.1    Pettit, A.2    Ohmura, K.3    Ortiz-Lopez, A.4    Duchatelle, V.5    Degott, C.6
  • 58
    • 0034888885 scopus 로고    scopus 로고
    • The genetic and immunopathological processes underlying collagen-induced arthritis
    • Luross JA, Williams NA,. The genetic and immunopathological processes underlying collagen-induced arthritis. Immunology 2001; 103: 407-16.
    • (2001) Immunology , vol.103 , pp. 407-416
    • Luross, J.A.1    Williams, N.A.2
  • 59
    • 0029875804 scopus 로고    scopus 로고
    • Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: A comparative study using anti-TNF α, anti-IL-1α/ β, and IL-1Ra
    • Joosten LA, Helsen MM, van de Loo FA, van den Berg WB,. Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: a comparative study using anti-TNF α, anti-IL-1α/β, and IL-1Ra. Arthritis Rheum 1996; 39: 797-809.
    • (1996) Arthritis Rheum , vol.39 , pp. 797-809
    • Joosten, L.A.1    Helsen, M.M.2    Van De Loo, F.A.3    Van Den Berg, W.B.4
  • 60
    • 0036166344 scopus 로고    scopus 로고
    • Suppression of autoimmune arthritis in interleukin-1-deficient mice in which T cell activation is impaired due to low levels of CD40 ligand and OX40 expression on T cells
    • Saijo S, Asano M, Horai R, Yamamoto H, Iwakura Y,. Suppression of autoimmune arthritis in interleukin-1-deficient mice in which T cell activation is impaired due to low levels of CD40 ligand and OX40 expression on T cells. Arthritis Rheum 2002; 46: 533-44.
    • (2002) Arthritis Rheum , vol.46 , pp. 533-544
    • Saijo, S.1    Asano, M.2    Horai, R.3    Yamamoto, H.4    Iwakura, Y.5
  • 61
    • 4344590199 scopus 로고    scopus 로고
    • Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice
    • et al.
    • Hata H, Sakaguchi N, Yoshitomi H, Iwakura Y, Sekikawa K, Azuma Y, et al. Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice. J Clin Invest 2004; 114: 582-8.
    • (2004) J Clin Invest , vol.114 , pp. 582-588
    • Hata, H.1    Sakaguchi, N.2    Yoshitomi, H.3    Iwakura, Y.4    Sekikawa, K.5    Azuma, Y.6
  • 63
    • 85047693264 scopus 로고    scopus 로고
    • TNF-α is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice
    • et al.
    • Horai R, Nakajima A, Habiro K, Kotani M, Nakae S, Matsuki T, et al. TNF-α is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice. J Clin Invest 2004; 114: 1603-11.
    • (2004) J Clin Invest , vol.114 , pp. 1603-1611
    • Horai, R.1    Nakajima, A.2    Habiro, K.3    Kotani, M.4    Nakae, S.5    Matsuki, T.6
  • 64
    • 32444441471 scopus 로고    scopus 로고
    • CD28-dependent differentiation into the effector/memory phenotype is essential for induction of arthritis in interleukin-1 receptor antagonist-deficient mice
    • et al.
    • Kotani M, Hirata K, Ogawa S, Habiro K, Ishida Y, Tanuma S, et al. CD28-dependent differentiation into the effector/memory phenotype is essential for induction of arthritis in interleukin-1 receptor antagonist-deficient mice. Arthritis Rheum 2006; 54: 473-81.
    • (2006) Arthritis Rheum , vol.54 , pp. 473-481
    • Kotani, M.1    Hirata, K.2    Ogawa, S.3    Habiro, K.4    Ishida, Y.5    Tanuma, S.6
  • 65
    • 0038623916 scopus 로고    scopus 로고
    • IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist
    • Nakae S, Saijo S, Horai R, Sudo K, Mori S, Iwakura Y,. IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist. Proc Natl Acad Sci U S A 2003; 100: 5986-90.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 5986-5990
    • Nakae, S.1    Saijo, S.2    Horai, R.3    Sudo, K.4    Mori, S.5    Iwakura, Y.6
  • 66
    • 55849150906 scopus 로고    scopus 로고
    • Interleukin-1 drives pathogenic Th17 cells during spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice
    • et al.
    • Koenders MI, Devesa I, Marijnissen RJ, Abdollahi-Roodsaz S, Boots AM, Walgreen B, et al. Interleukin-1 drives pathogenic Th17 cells during spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice. Arthritis Rheum 2008; 58: 3461-70.
    • (2008) Arthritis Rheum , vol.58 , pp. 3461-3470
    • Koenders, M.I.1    Devesa, I.2    Marijnissen, R.J.3    Abdollahi-Roodsaz, S.4    Boots, A.M.5    Walgreen, B.6
  • 69
    • 84867112016 scopus 로고    scopus 로고
    • Th1 and Th17 cell subpopulations are enriched in the peripheral blood of patients with systemic juvenile idiopathic arthritis
    • et al.
    • Omoyinmi E, Hamaoui R, Pesenacker A, Nistala K, Moncrieffe H, Ursu S, et al. Th1 and Th17 cell subpopulations are enriched in the peripheral blood of patients with systemic juvenile idiopathic arthritis. Rheumatology (Oxford) 2012; 51: 1881-6.
    • (2012) Rheumatology (Oxford) , vol.51 , pp. 1881-1886
    • Omoyinmi, E.1    Hamaoui, R.2    Pesenacker, A.3    Nistala, K.4    Moncrieffe, H.5    Ursu, S.6
  • 70
    • 0033512202 scopus 로고    scopus 로고
    • Identification of a genetic risk factor for systemic juvenile rheumatoid arthritis in the 5-flanking region of the TNFα gene and HLA genes
    • et al.
    • Date Y, Seki N, Kamizono S, Higuchi T, Hirata T, Miyata K, et al. Identification of a genetic risk factor for systemic juvenile rheumatoid arthritis in the 5-flanking region of the TNFα gene and HLA genes. Arthritis Rheum 1999; 42: 2577-82.
    • (1999) Arthritis Rheum , vol.42 , pp. 2577-2582
    • Date, Y.1    Seki, N.2    Kamizono, S.3    Higuchi, T.4    Hirata, T.5    Miyata, K.6
  • 71
    • 0036797034 scopus 로고    scopus 로고
    • Juvenile idiopathic arthritis classified by the ILAR criteria: HLA associations in UK patients
    • et al.
    • Thomson W, Barrett JH, Donn R, Pepper L, Kennedy LJ, Ollier WE, et al. Juvenile idiopathic arthritis classified by the ILAR criteria: HLA associations in UK patients. Rheumatology (Oxford) 2002; 41: 1183-9.
    • (2002) Rheumatology (Oxford) , vol.41 , pp. 1183-1189
    • Thomson, W.1    Barrett, J.H.2    Donn, R.3    Pepper, L.4    Kennedy, L.J.5    Ollier, W.E.6
  • 72
    • 84901634061 scopus 로고    scopus 로고
    • Genome wide association meta-analysis implicates HLA-DRB1, the BTNL2/HLA-DRA region, and a novel susceptibility locus on chromosome 1 in systemic juvenile idiopathic arthritis
    • [abstract].
    • Ombrello MJ, Remmers EF, Tachmazidou I, Grom AA, Foll D, Martini A, et al. Genome wide association meta-analysis implicates HLA-DRB1, the BTNL2/HLA-DRA region, and a novel susceptibility locus on chromosome 1 in systemic juvenile idiopathic arthritis [abstract]. Arthritis Rheum 2013; 65 Suppl: S937.
    • (2013) Arthritis Rheum , vol.65 , Issue.SUPPL.
    • Ombrello, M.J.1    Remmers, E.F.2    Tachmazidou, I.3    Grom, A.A.4    Foll, D.5    Et Al., M.A.6
  • 73
    • 78650869495 scopus 로고    scopus 로고
    • Combination therapy of abatacept and anakinra in children with refractory systemic juvenile idiopathic arthritis: A retrospective case series
    • Record JL, Beukelman T, Cron RQ,. Combination therapy of abatacept and anakinra in children with refractory systemic juvenile idiopathic arthritis: a retrospective case series. J Rheumatol 2011; 38: 180-1.
    • (2011) J Rheumatol , vol.38 , pp. 180-181
    • Record, J.L.1    Beukelman, T.2    Cron, R.Q.3
  • 74
    • 84873184774 scopus 로고    scopus 로고
    • Distinct subsets of patients with systemic juvenile idiopathic arthritis based on their cytokine profiles
    • Shimizu M, Nakagishi Y, Yachie A,. Distinct subsets of patients with systemic juvenile idiopathic arthritis based on their cytokine profiles. Cytokine 2013; 61: 345-8.
    • (2013) Cytokine , vol.61 , pp. 345-348
    • Shimizu, M.1    Nakagishi, Y.2    Yachie, A.3
  • 78
    • 0037338925 scopus 로고    scopus 로고
    • Natural killer cell dysfunction in patients with systemic-onset juvenile rheumatoid arthritis and macrophage activation syndrome
    • Grom AA, Villanueva J, Lee S, Goldmuntz EA, Passo MH, Filipovich A,. Natural killer cell dysfunction in patients with systemic-onset juvenile rheumatoid arthritis and macrophage activation syndrome. J Pediatr 2003; 142: 292-6.
    • (2003) J Pediatr , vol.142 , pp. 292-296
    • Grom, A.A.1    Villanueva, J.2    Lee, S.3    Goldmuntz, E.A.4    Passo, M.H.5    Filipovich, A.6
  • 79
    • 0037293064 scopus 로고    scopus 로고
    • Reduced perforin expression in systemic juvenile idiopathic arthritis is restored by autologous stem-cell transplantation
    • Wulffraat NM, Rijkers GT, Elst E, Brooimans R, Kuis W,. Reduced perforin expression in systemic juvenile idiopathic arthritis is restored by autologous stem-cell transplantation. Rheumatology (Oxford) 2003; 42: 375-9.
    • (2003) Rheumatology (Oxford) , vol.42 , pp. 375-379
    • Wulffraat, N.M.1    Rijkers, G.T.2    Elst, E.3    Brooimans, R.4    Kuis, W.5
  • 80
    • 39749185953 scopus 로고    scopus 로고
    • Mutations of the hemophagocytic lymphohistiocytosis-associated gene UNC13D in a patient with systemic juvenile idiopathic arthritis
    • et al.
    • Hazen MM, Woodward AL, Hofmann I, Degar BA, Grom A, Filipovich AH, et al. Mutations of the hemophagocytic lymphohistiocytosis-associated gene UNC13D in a patient with systemic juvenile idiopathic arthritis. Arthritis Rheum 2008; 58: 567-70.
    • (2008) Arthritis Rheum , vol.58 , pp. 567-570
    • Hazen, M.M.1    Woodward, A.L.2    Hofmann, I.3    Degar, B.A.4    Grom, A.5    Filipovich, A.H.6
  • 81
    • 77950531755 scopus 로고    scopus 로고
    • Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis
    • et al.
    • Vastert SJ, van Wijk R, D'Urbano LE, de Vooght KM, de Jager W, Ravelli A, et al. Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis. Rheumatology (Oxford) 2010; 49: 441-9.
    • (2010) Rheumatology (Oxford) , vol.49 , pp. 441-449
    • Vastert, S.J.1    Van Wijk, R.2    D'Urbano, L.E.3    De Vooght, K.M.4    De Jager, W.5    Ravelli, A.6
  • 82
    • 21744452702 scopus 로고    scopus 로고
    • Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome
    • et al.
    • Villanueva J, Lee S, Giannini EH, Graham TB, Passo MH, Filipovich A, et al. Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome. Arthritis Res Ther 2005; 7: R30-7.
    • (2005) Arthritis Res Ther , vol.7
    • Villanueva, J.1    Lee, S.2    Giannini, E.H.3    Graham, T.B.4    Passo, M.H.5    Filipovich, A.6
  • 83
    • 84876730706 scopus 로고    scopus 로고
    • Pulmonary hypertension and other potentially fatal pulmonary complications in systemic juvenile idiopathic arthritis
    • et al, and the Childhood Arthritis and Rheumatology Research Alliance CARRA net Investigators.
    • Kimura Y, Weiss JE, Haroldson KL, Lee T, Punaro M, Oliveira S, et al, and the Childhood Arthritis and Rheumatology Research Alliance CARRA net Investigators. Pulmonary hypertension and other potentially fatal pulmonary complications in systemic juvenile idiopathic arthritis. Arthritis Care Res (Hoboken) 2013; 65: 745-52.
    • (2013) Arthritis Care Res (Hoboken) , vol.65 , pp. 745-752
    • Kimura, Y.1    Weiss, J.E.2    Haroldson, K.L.3    Lee, T.4    Punaro, M.5    Oliveira, S.6
  • 84
    • 84864420538 scopus 로고    scopus 로고
    • Rates of hospitalized bacterial infection associated with juvenile idiopathic arthritis and its treatment
    • et al, on behalf of the SABER Collaboration.
    • Beukelman T, Xie F, Chen L, Baddley JW, Delzell E, Grijalva CG, et al, on behalf of the SABER Collaboration. Rates of hospitalized bacterial infection associated with juvenile idiopathic arthritis and its treatment. Arthritis Rheum 2012; 64: 2773-80.
    • (2012) Arthritis Rheum , vol.64 , pp. 2773-2780
    • Beukelman, T.1    Xie, F.2    Chen, L.3    Baddley, J.W.4    Delzell, E.5    Grijalva, C.G.6
  • 85
    • 0028239555 scopus 로고
    • Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome: Results from a randomized, double-blind, placebo-controlled trial
    • et al.
    • Fisher CJ Jr, Dhainaut JF, Opal SM, Pribble JP, Balk RA, Slotman GJ, et al. Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome: results from a randomized, double-blind, placebo-controlled trial. JAMA 1994; 271: 1836-43.
    • (1994) JAMA , vol.271 , pp. 1836-1843
    • Fisher Jr., C.J.1    Dhainaut, J.F.2    Opal, S.M.3    Pribble, J.P.4    Balk, R.A.5    Slotman, G.J.6


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