Novel regulatory principles of the spliceosomal Brr2 RNA helicase and links to retinal disease in humans

RNA Biology

Volumn 11, Issue 4, 2014, Pages 298-312

  Mozaffari Jovin, Sina ^a   Wandersleben, Traudy ^b   Santos, Karine F ^b   Will, Cindy L ^a   Luḧrmann, Reinhard ^a   Wahl, Markus C ^b  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Pre mRNA splicing; Retinitis pigmentosa; RNA helicase; RNA protein complex; Spliceosome catalytic activation

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BRR2 RNA HELICASE; PROTEIN; PRP8 PROTEIN; RNA HELICASE; UNCLASSIFIED DRUG; COPS5 PROTEIN, HUMAN; PEPTIDE HYDROLASE; PROTEIN BINDING; PRPF8 PROTEIN, HUMAN; RNA BINDING PROTEIN; RNA PRECURSOR; SIGNAL PEPTIDE; SMALL NUCLEAR RIBONUCLEOPROTEIN; SNRNP200 PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; ENZYME RELEASE; ENZYME STRUCTURE; GENE MUTATION; HUMAN; JAB1 DOMAIN; MPN LIKE DOMAIN; NONHUMAN; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RETINA DISEASE; RETINITIS PIGMENTOSA; REVIEW; RH DOMAIN; RNA BINDING; RNA SPLICING; RP13 DISEASE; SPLICEOSOME; SURFACE PLASMON RESONANCE; CHEMISTRY; ENZYME SPECIFICITY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PROTEIN CONFORMATION;

GENE EXPRESSION REGULATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PEPTIDE HYDROLASES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; RETINAL DISEASES; RIBONUCLEOPROTEINS, SMALL NUCLEAR; RNA PRECURSORS; RNA SPLICING; RNA-BINDING PROTEINS; SPLICEOSOMES; SUBSTRATE SPECIFICITY;

EID: 84901464971     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.4161/rna.28353     Document Type: Review

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