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Volumn 20, Issue 1, 2014, Pages 46-60

An unanticipated early function of DEAD-box ATPase Prp28 during commitment to splicing is modulated by U5 snRNP protein Prp8

Author keywords

Commitment complex; Pre mRNA splicing; Pre spliceosome; Prp28; Prp8

Indexed keywords

DEAD BOX PROTEIN; DEAD BOX PROTEIN PRP28; SMALL NUCLEAR RIBONUCLEOPROTEIN; SMALL NUCLEAR RIBONUCLEOPROTEIN PRP8; UNCLASSIFIED DRUG;

EID: 84890659579     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.041970.113     Document Type: Article
Times cited : (18)

References (70)
  • 1
    • 0030911051 scopus 로고    scopus 로고
    • Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals
    • Abovich N, Rosbash M. 1997. Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals. Cell 89: 403-412.
    • (1997) Cell , vol.89 , pp. 403-412
    • Abovich, N.1    Rosbash, M.2
  • 2
    • 0030914332 scopus 로고    scopus 로고
    • A novel U1/U5 interaction indicates proximity between U1 and U5 snRNAs during an early step of mRNA splicing
    • Ast G, Weiner AM. 1997. A novel U1/U5 interaction indicates proximity between U1 and U5 snRNAs during an early step of mRNA splicing. RNA 3: 371-381.
    • (1997) RNA , vol.3 , pp. 371-381
    • Ast, G.1    Weiner, A.M.2
  • 3
    • 33646173207 scopus 로고    scopus 로고
    • Assembly of Snu114 into U5 snRNP requires Prp8 and a functional GTPase domain
    • Brenner TJ, Guthrie C. 2006. Assembly of Snu114 into U5 snRNP requires Prp8 and a functional GTPase domain. RNA 12: 862-871.
    • (2006) RNA , vol.12 , pp. 862-871
    • Brenner, T.J.1    Guthrie, C.2
  • 4
    • 0036948420 scopus 로고    scopus 로고
    • Allosteric cascade of spliceosome activation
    • Brow DA. 2002. Allosteric cascade of spliceosome activation. Annu Rev Genet 36: 333-360.
    • (2002) Annu Rev Genet , vol.36 , pp. 333-360
    • Brow, D.A.1
  • 5
    • 0027287852 scopus 로고
    • A mechanism to enhance mRNA splicing fidelity: The RNA-dependent ATPase Prp16 governs usage of a discard pathway for aberrant lariat intermediates
    • Burgess SM, Guthrie C. 1993. A mechanism to enhance mRNA splicing fidelity: The RNA-dependent ATPase Prp16 governs usage of a discard pathway for aberrant lariat intermediates. Cell 73: 1377-1391.
    • (1993) Cell , vol.73 , pp. 1377-1391
    • Burgess, S.M.1    Guthrie, C.2
  • 6
    • 0035105921 scopus 로고    scopus 로고
    • Specific alterations of U1-C protein or U1 small nuclear RNA can eliminate the requirement of Prp28p, an essential DEAD box splicing factor
    • Chen JY-F, Stands L, Staley JP, Jackups RR Jr, Latus LJ, Chang T-H. 2001. Specific alterations of U1-C protein or U1 small nuclear RNA can eliminate the requirement of Prp28p, an essential DEAD box splicing factor. Mol Cell 7: 227-232.
    • (2001) Mol Cell , vol.7 , pp. 227-232
    • Chen, J.Y.-F.1    Stands, L.2    Staley, J.P.3    Jackups Jr., R.R.4    Latus, L.J.5    Chang, T.-H.6
  • 7
    • 79955031925 scopus 로고    scopus 로고
    • Prp8, the pivotal protein of the spliceosomal catalytic center, evolved from a retroelement-encoded reverse transcriptase
    • DlakicM, Mushegian A. 2011. Prp8, the pivotal protein of the spliceosomal catalytic center, evolved from a retroelement-encoded reverse transcriptase. RNA 17: 799-808.
    • (2011) RNA , vol.17 , pp. 799-808
    • Dlakic, M.1    Mushegian, A.2
  • 8
    • 70449625597 scopus 로고    scopus 로고
    • The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome
    • Fabrizio P, Dannenberg J, Dube P, Kastner B, Stark H, Urlaub H, Lührmann R. 2009. The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Mol Cell 36: 593-608.
    • (2009) Mol Cell , vol.36 , pp. 593-608
    • Fabrizio, P.1    Dannenberg, J.2    Dube, P.3    Kastner, B.4    Stark, H.5    Urlaub, H.6    Lührmann, R.7
  • 10
    • 84864578590 scopus 로고    scopus 로고
    • The bromodomain interaction module
    • Filippakopoulos P, Knapp S. 2012. The bromodomain interaction module. FEBS Lett 586: 2692-2704.
    • (2012) FEBS Lett , vol.586 , pp. 2692-2704
    • Filippakopoulos, P.1    Knapp, S.2
  • 11
    • 84873629024 scopus 로고    scopus 로고
    • Crystal structure of Prp8 reveals active site cavity of the spliceosome
    • Galej WP, Oubridge C, Newman AJ, Nagai K. 2013. Crystal structure of Prp8 reveals active site cavity of the spliceosome. Nature 493: 638-643.
    • (2013) Nature , vol.493 , pp. 638-643
    • Galej, W.P.1    Oubridge, C.2    Newman, A.J.3    Nagai, K.4
  • 12
    • 21244493903 scopus 로고    scopus 로고
    • Cotranscriptional spliceosome assembly occurs in a stepwise fashion and requires the cap binding complex
    • Görnemann J, Kotovic KM, Hujer K, Neugebauer KM. 2005. Cotranscriptional spliceosome assembly occurs in a stepwise fashion and requires the cap binding complex. Mol Cell 19: 53-63.
    • (2005) Mol Cell , vol.19 , pp. 53-63
    • Görnemann, J.1    Kotovic, K.M.2    Hujer, K.3    Neugebauer, K.M.4
  • 14
    • 0033575711 scopus 로고    scopus 로고
    • Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6U5] tri-snRNP
    • Gottschalk A, Neubauer G, Banroques J, Mann M, Lührmann R, Fabrizio P. 1999. Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6U5] tri-snRNP. EMBO J 18: 4535-4548.
    • (1999) EMBO J , vol.18 , pp. 4535-4548
    • Gottschalk, A.1    Neubauer, G.2    Banroques, J.3    Mann, M.4    Lührmann, R.5    Fabrizio, P.6
  • 15
    • 0035161659 scopus 로고    scopus 로고
    • The yeast U5 snRNP coisolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2p
    • Gottschalk A, Kastner B, Lührmann R, Fabrizio P. 2001. The yeast U5 snRNP coisolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2p. RNA 7: 1554-1565.
    • (2001) RNA , vol.7 , pp. 1554-1565
    • Gottschalk, A.1    Kastner, B.2    Lührmann, R.3    Fabrizio, P.4
  • 16
    • 17844395704 scopus 로고    scopus 로고
    • Prp8 protein: At the heart of the spliceosome
    • Grainger RJ, Beggs JD. 2005. Prp8 protein: At the heart of the spliceosome. RNA 11: 533-557.
    • (2005) RNA , vol.11 , pp. 533-557
    • Grainger, R.J.1    Beggs, J.D.2
  • 17
    • 0025977037 scopus 로고
    • Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase
    • Guan KL, Dixon JE. 1991. Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal Biochem 192: 262-267.
    • (1991) Anal Biochem , vol.192 , pp. 262-267
    • Guan, K.L.1    Dixon, J.E.2
  • 18
    • 67650096783 scopus 로고    scopus 로고
    • A targeted bypass screen identifies Ynl187p, Prp42p, Snu71p, and Cbp80p for stable U1 snRNP/Pre-mRNA interaction
    • Hage R, Tung L, Du H, Stands L, Rosbash M, Chang T-H. 2009. A targeted bypass screen identifies Ynl187p, Prp42p, Snu71p, and Cbp80p for stable U1 snRNP/Pre-mRNA interaction. Mol Cell Biol 29: 3941-3952.
    • (2009) Mol Cell Biol , vol.29 , pp. 3941-3952
    • Hage, R.1    Tung, L.2    Du, H.3    Stands, L.4    Rosbash, M.5    Chang, T.-H.6
  • 21
    • 0035256812 scopus 로고    scopus 로고
    • The 100-kDa U5 snRNP protein (hPrp28p) contacts the 5 splice site through its ATPase site
    • Ismaili N, Sha M, Gustafson EH, Konarska MM. 2001. The 100-kDa U5 snRNP protein (hPrp28p) contacts the 5 splice site through its ATPase site. RNA 7: 182-193.
    • (2001) RNA , vol.7 , pp. 182-193
    • Ismaili, N.1    Sha, M.2    Gustafson, E.H.3    Konarska, M.M.4
  • 22
    • 0035177309 scopus 로고    scopus 로고
    • Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for Sub2, an essential spliceosomal ATPase
    • Kistler AL, Guthrie C. 2001. Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for Sub2, an essential spliceosomal ATPase. Genes Dev 15: 42-49.
    • (2001) Genes Dev , vol.15 , pp. 42-49
    • Kistler, A.L.1    Guthrie, C.2
  • 23
    • 0032775010 scopus 로고    scopus 로고
    • Epitope tagging of yeast genes using a PCR-based strategy: More tags and improved practical routines
    • Knop M, Siegers K, Pereira G, Zachariae W, Winsor B, Nasmyth K, Schiebel E. 1999. Epitope tagging of yeast genes using a PCR-based strategy: More tags and improved practical routines. Yeast 15: 963-972.
    • (1999) Yeast , vol.15 , pp. 963-972
    • Knop, M.1    Siegers, K.2    Pereira, G.3    Zachariae, W.4    Winsor, B.5    Nasmyth, K.6    Schiebel, E.7
  • 24
    • 67649337263 scopus 로고    scopus 로고
    • DExD/H-box Prp5 protein is in the spliceosome during most of the splicing cycle
    • Kosowski TR, Keys HR, Quan TK, Ruby SW. 2009. DExD/H-box Prp5 protein is in the spliceosome during most of the splicing cycle. RNA 15: 1345-1362.
    • (2009) RNA , vol.15 , pp. 1345-1362
    • Kosowski, T.R.1    Keys, H.R.2    Quan, T.K.3    Ruby, S.W.4
  • 25
    • 0041630999 scopus 로고    scopus 로고
    • Cotranscriptional recruitment of the U1 snRNP to intron-containing genes in yeast
    • Kotovic KM, Lockshon D, Boric L, Neugebauer KM. 2003. Cotranscriptional recruitment of the U1 snRNP to intron-containing genes in yeast. Mol Cell Biol 23: 5768-5779.
    • (2003) Mol Cell Biol , vol.23 , pp. 5768-5779
    • Kotovic, K.M.1    Lockshon, D.2    Boric, L.3    Neugebauer, K.M.4
  • 26
    • 0033900068 scopus 로고    scopus 로고
    • Suppressors of a cold-sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8 that influence spliceosome activation
    • Kuhn AN, Brow DA. 2000. Suppressors of a cold-sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8 that influence spliceosome activation. Genetics 155: 1667-1682.
    • (2000) Genetics , vol.155 , pp. 1667-1682
    • Kuhn, A.N.1    Brow, D.A.2
  • 27
    • 0033047503 scopus 로고    scopus 로고
    • Splicing factor Prp8 governs U4/U6 RNA unwinding during activation of the spliceosome
    • Kuhn AN, Li Z, Brow DA. 1999. Splicing factor Prp8 governs U4/U6 RNA unwinding during activation of the spliceosome. Mol Cell 3: 65-75.
    • (1999) Mol Cell , vol.3 , pp. 65-75
    • Kuhn, A.N.1    Li, Z.2    Brow, D.A.3
  • 28
    • 0037047049 scopus 로고    scopus 로고
    • Distinct domains of splicing factor Prp8 mediate different aspects of spliceosome activation
    • Kuhn AN, Reichl EM, Brow DA. 2002. Distinct domains of splicing factor Prp8 mediate different aspects of spliceosome activation. Proc Natl Acad Sci 99: 9145-9149.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 9145-9149
    • Kuhn, A.N.1    Reichl, E.M.2    Brow, D.A.3
  • 29
    • 21244469725 scopus 로고    scopus 로고
    • Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5ss base pairing in yeast
    • Lacadie SA, Rosbash M. 2005. Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5ss base pairing in yeast. Mol Cell 19: 65-75.
    • (2005) Mol Cell , vol.19 , pp. 65-75
    • Lacadie, S.A.1    Rosbash, M.2
  • 30
    • 33746630487 scopus 로고    scopus 로고
    • In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants
    • Lacadie SA, Tardiff DF, Kadener S, Rosbash M. 2006. In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants. Genes Dev 20: 2055-2066.
    • (2006) Genes Dev , vol.20 , pp. 2055-2066
    • Lacadie, S.A.1    Tardiff, D.F.2    Kadener, S.3    Rosbash, M.4
  • 31
    • 0027516055 scopus 로고
    • Mutational analysis of pre-mRNA splicing in Saccharomyces cerevisiae using a sensitive new reporter gene, CUP1
    • Lesser CF, Guthrie C. 1993. Mutational analysis of pre-mRNA splicing in Saccharomyces cerevisiae using a sensitive new reporter gene, CUP1. Genetics 133: 851-863.
    • (1993) Genetics , vol.133 , pp. 851-863
    • Lesser, C.F.1    Guthrie, C.2
  • 33
    • 0035180388 scopus 로고    scopus 로고
    • Multiple roles for the yeast SUB2/yUAP56 gene in splicing
    • Libri D, Graziani N, Saguez C, Boulay J. 2001. Multiple roles for the yeast SUB2/yUAP56 gene in splicing. Genes Dev 15: 36-41.
    • (2001) Genes Dev , vol.15 , pp. 36-41
    • Libri, D.1    Graziani, N.2    Saguez, C.3    Boulay, J.4
  • 35
    • 58149231008 scopus 로고    scopus 로고
    • ATP-dependent unwinding of U4/U6 snRNAs by the Brr2 helicase requires the C terminus of Prp8
    • Maeder C, Kutach AK, Guthrie C. 2008. ATP-dependent unwinding of U4/U6 snRNAs by the Brr2 helicase requires the C terminus of Prp8. Nat Struct Mol Biol 16: 42-48.
    • (2008) Nat Struct Mol Biol , vol.16 , pp. 42-48
    • Maeder, C.1    Kutach, A.K.2    Guthrie, C.3
  • 36
    • 0033634673 scopus 로고    scopus 로고
    • Functional recognition of the 5 splice site by U4/U6.U5 tri-snRNP defines a novel ATPdependent step in early spliceosome assembly
    • Maroney PA, Romfo CM, Nilsen TW. 2000. Functional recognition of the 5 splice site by U4/U6.U5 tri-snRNP defines a novel ATPdependent step in early spliceosome assembly. Mol Cell 6: 317-328.
    • (2000) Mol Cell , vol.6 , pp. 317-328
    • Maroney, P.A.1    Romfo, C.M.2    Nilsen, T.W.3
  • 37
    • 43249109907 scopus 로고    scopus 로고
    • Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome
    • Mathew R, Hartmuth K, Möhlmann S, Urlaub H, Ficner R, Lührmann R. 2008. Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome. Nat Struct Mol Biol 15: 435-443.
    • (2008) Nat Struct Mol Biol , vol.15 , pp. 435-443
    • Mathew, R.1    Hartmuth, K.2    Möhlmann, S.3    Urlaub, H.4    Ficner, R.5    Lührmann, R.6
  • 38
    • 84868583242 scopus 로고    scopus 로고
    • The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA
    • Mozaffari-Jovin S, Santos KF, Hsiao H-H, Will CL, Urlaub H, Wahl MC, Lührmann R. 2012. The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA. Genes Dev 26: 2422-2434.
    • (2012) Genes Dev , vol.26 , pp. 2422-2434
    • Mozaffari-Jovin, S.1    Santos, K.F.2    Hsiao, H.-H.3    Will, C.L.4    Urlaub, H.5    Wahl, M.C.6    Lührmann, R.7
  • 40
    • 0029400769 scopus 로고
    • SnRNA interactions at 5 and 3 splice sites monitored by photoactivated crosslinking in yeast spliceosomes
    • Newman AJ, Teigelkamp S, Beggs JD. 1995. snRNA interactions at 5 and 3 splice sites monitored by photoactivated crosslinking in yeast spliceosomes. RNA 1: 968-980.
    • (1995) RNA , vol.1 , pp. 968-980
    • Newman, A.J.1    Teigelkamp, S.2    Beggs, J.D.3
  • 41
    • 33847053558 scopus 로고    scopus 로고
    • Structure of a multipartite protein-protein interaction domain in splicing factor Prp8 and its link to retinitis pigmentosa
    • Pena V, Liu S, Bujnicki JM, Lührmann R, Wahl MC. 2007. Structure of a multipartite protein-protein interaction domain in splicing factor Prp8 and its link to retinitis pigmentosa. Mol Cell 25: 615-624.
    • (2007) Mol Cell , vol.25 , pp. 615-624
    • Pena, V.1    Liu, S.2    Bujnicki, J.M.3    Lührmann, R.4    Wahl, M.C.5
  • 42
    • 55549143970 scopus 로고    scopus 로고
    • Structure and function of an RNase H domain at the heart of the spliceosome
    • Pena V, Rozov A, Fabrizio P, Lührmann R, Wahl MC. 2008. Structure and function of an RNase H domain at the heart of the spliceosome. EMBO J 27: 2929-2940.
    • (2008) EMBO J , vol.27 , pp. 2929-2940
    • Pena, V.1    Rozov, A.2    Fabrizio, P.3    Lührmann, R.4    Wahl, M.C.5
  • 43
    • 0345564842 scopus 로고    scopus 로고
    • ATP requirement for Prp5p function is determined by Cus2p and the structure of U2 small nuclear RNA
    • Perriman R, Barta I, Voeltz GK, Abelson J, Ares M. 2003. ATP requirement for Prp5p function is determined by Cus2p and the structure of U2 small nuclear RNA. Proc Natl Acad Sci 100: 13857-13862.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 13857-13862
    • Perriman, R.1    Barta, I.2    Voeltz, G.K.3    Abelson, J.4    Ares, M.5
  • 44
    • 34247255773 scopus 로고    scopus 로고
    • Transcript specificity in yeast pre-mRNA splicing revealed by mutations in core spliceosomal components
    • Pleiss JA, Whitworth GB, Bergkessel M, Guthrie C. 2007. Transcript specificity in yeast pre-mRNA splicing revealed by mutations in core spliceosomal components. PLoS Biol 5: E90.
    • (2007) PLoS Biol , vol.5
    • Pleiss, J.A.1    Whitworth, G.B.2    Bergkessel, M.3    Guthrie, C.4
  • 45
    • 84859224256 scopus 로고    scopus 로고
    • Diverse forms of RPS9 splicing are part of an evolving autoregulatory circuit
    • Plocik AM, Guthrie C. 2012. Diverse forms of RPS9 splicing are part of an evolving autoregulatory circuit. PLoS Genet 8: E1002620.
    • (2012) PLoS Genet , vol.8
    • Plocik, A.M.1    Guthrie, C.2
  • 46
    • 0032537739 scopus 로고    scopus 로고
    • RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2
    • Raghunathan PL, Guthrie C. 1998. RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2. Curr Biol 8: 847-855.
    • (1998) Curr Biol , vol.8 , pp. 847-855
    • Raghunathan, P.L.1    Guthrie, C.2
  • 50
    • 84883480928 scopus 로고    scopus 로고
    • Structure-function analysis of the 5 end of yeast U1 snRNA highlights genetic interactions with the Msl5•Mud2 branchpoint-binding complex and other spliceosome assembly factors
    • Schwer B, Chang J, Shuman S. 2013. Structure-function analysis of the 5 end of yeast U1 snRNA highlights genetic interactions with the Msl5•Mud2 branchpoint-binding complex and other spliceosome assembly factors. Nucleic Acids Res 41: 7485-7500.
    • (2013) Nucleic Acids Res , vol.41 , pp. 7485-7500
    • Schwer, B.1    Chang, J.2    Shuman, S.3
  • 51
    • 0024325159 scopus 로고
    • Identification of functional U1 snRNApre-mRNA complexes committed to spliceosome assembly and splicing
    • Seraphin B, Rosbash M. 1989. Identification of functional U1 snRNApre-mRNA complexes committed to spliceosome assembly and splicing. Cell 59: 349-358.
    • (1989) Cell , vol.59 , pp. 349-358
    • Seraphin, B.1    Rosbash, M.2
  • 52
    • 0025733098 scopus 로고
    • The yeast branchpoint sequence is not required for the formation of a stable U1 snRNA-pre-mRNA complex and is recognized in the absence of U2 snRNA
    • Seraphin B, Rosbash M. 1991. The yeast branchpoint sequence is not required for the formation of a stable U1 snRNA-pre-mRNA complex and is recognized in the absence of U2 snRNA. EMBO J 10: 1209-1216.
    • (1991) EMBO J , vol.10 , pp. 1209-1216
    • Seraphin, B.1    Rosbash, M.2
  • 53
    • 33746441457 scopus 로고    scopus 로고
    • The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase
    • Small EC, Leggett SR, Winans AA, Staley JP. 2006. The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase. Mol Cell 23: 389-399.
    • (2006) Mol Cell , vol.23 , pp. 389-399
    • Small, E.C.1    Leggett, S.R.2    Winans, A.A.3    Staley, J.P.4
  • 54
    • 0033010430 scopus 로고    scopus 로고
    • An RNA switch at the 5 splice site requires ATP and the DEAD box protein Prp28p
    • Staley JP, Guthrie C. 1999. An RNA switch at the 5 splice site requires ATP and the DEAD box protein Prp28p. Mol Cell 3: 55-64.
    • (1999) Mol Cell , vol.3 , pp. 55-64
    • Staley, J.P.1    Guthrie, C.2
  • 55
    • 0035161567 scopus 로고    scopus 로고
    • Biochemical and genetic analyses of the U5, U6, and U4/U6U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae
    • Stevens SW, Barta I, Ge HY, Moore RE, Young MK, Lee TD, Abelson J. 2001. Biochemical and genetic analyses of the U5, U6, and U4/U6U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae. RNA 7: 1543-1553.
    • (2001) RNA , vol.7 , pp. 1543-1553
    • Stevens, S.W.1    Barta, I.2    Ge, H.Y.3    Moore, R.E.4    Young, M.K.5    Lee, T.D.6    Abelson, J.7
  • 56
    • 0025860028 scopus 로고
    • A cold-sensitive mRNA splicing mutant is a member of the RNA helicase gene family
    • Strauss EJ, Guthrie C. 1991. A cold-sensitive mRNA splicing mutant is a member of the RNA helicase gene family. Genes Dev 5: 629-641.
    • (1991) Genes Dev , vol.5 , pp. 629-641
    • Strauss, E.J.1    Guthrie, C.2
  • 57
    • 0028096619 scopus 로고
    • PRP28, a "dEAD-box" protein, is required for the first step of mRNA splicing in vitro
    • Strauss EJ, Guthrie C. 1994. PRP28, a "DEAD-box" protein, is required for the first step of mRNA splicing in vitro. Nucleic Acids Res 22: 3187-3193.
    • (1994) Nucleic Acids Res , vol.22 , pp. 3187-3193
    • Strauss, E.J.1    Guthrie, C.2
  • 58
    • 0030696683 scopus 로고    scopus 로고
    • The human U5 snRNP-specific 100-kD protein is an RS domain-containing, putative RNA helicase with significant homology to the yeast splicing factor Prp28p
    • Teigelkamp S, Mundt C, Achsel T, Will CL, Lührmann R. 1997. The human U5 snRNP-specific 100-kD protein is an RS domain-containing, putative RNA helicase with significant homology to the yeast splicing factor Prp28p. RNA 3: 1313-1326.
    • (1997) RNA , vol.3 , pp. 1313-1326
    • Teigelkamp, S.1    Mundt, C.2    Achsel, T.3    Will, C.L.4    Lührmann, R.5
  • 59
    • 0028960809 scopus 로고
    • A novel role for a U5 snRNP protein in 3 splice site selection
    • Umen JG, Guthrie C. 1995. A novel role for a U5 snRNP protein in 3 splice site selection. Genes Dev 9: 855-868.
    • (1995) Genes Dev , vol.9 , pp. 855-868
    • Umen, J.G.1    Guthrie, C.2
  • 60
    • 0030030194 scopus 로고    scopus 로고
    • Mutagenesis of the yeast gene PRP8 reveals domains governing the specificity and fidelity of 3 splice site selection
    • Umen JG, Guthrie C. 1996. Mutagenesis of the yeast gene PRP8 reveals domains governing the specificity and fidelity of 3 splice site selection. Genetics 143: 723-739.
    • (1996) Genetics , vol.143 , pp. 723-739
    • Umen, J.G.1    Guthrie, C.2
  • 61
    • 0035053295 scopus 로고    scopus 로고
    • Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae
    • van Nues RW, Beggs JD. 2001. Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae. Genetics 157: 1451-1467.
    • (2001) Genetics , vol.157 , pp. 1451-1467
    • Van Nues, R.W.1    Beggs, J.D.2
  • 62
    • 0022747370 scopus 로고
    • Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome
    • Vijayraghavan U, Parker R, Tamm J, Iimura Y, Rossi J, Abelson J, Guthrie C. 1986. Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome. EMBO J 5: 1683-1695.
    • (1986) EMBO J , vol.5 , pp. 1683-1695
    • Vijayraghavan, U.1    Parker, R.2    Tamm, J.3    Iimura, Y.4    Rossi, J.5    Abelson, J.6    Guthrie, C.7
  • 63
    • 0026670431 scopus 로고
    • Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing
    • Wassarman DA, Steitz JA. 1992. Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing. Science 257: 1918-1925.
    • (1992) Science , vol.257 , pp. 1918-1925
    • Wassarman, D.A.1    Steitz, J.A.2
  • 66
    • 0027059033 scopus 로고
    • Site-specific cross-linking of mammalian U5 snRNP to the 5 splice site before the first step of pre-mRNA splicing
    • Wyatt JR, Sontheimer EJ, Steitz JA. 1992. Site-specific cross-linking of mammalian U5 snRNP to the 5 splice site before the first step of pre-mRNA splicing. Genes Dev 6: 2542-2553.
    • (1992) Genes Dev , vol.6 , pp. 2542-2553
    • Wyatt, J.R.1    Sontheimer, E.J.2    Steitz, J.A.3
  • 67
    • 1542380571 scopus 로고    scopus 로고
    • Prp5 bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA
    • Xu Y-Z, Newnham CM, Kameoka S, Huang T, Konarska MM, Query CC. 2004. Prp5 bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA. EMBO J 23: 376-385.
    • (2004) EMBO J , vol.23 , pp. 376-385
    • Xu, Y.-Z.1    Newnham, C.M.2    Kameoka, S.3    Huang, T.4    Konarska, M.M.5    Query, C.C.6
  • 68
    • 52949131890 scopus 로고    scopus 로고
    • Crystal structure of the -finger domain of Prp8 reveals analogy to ribosomal proteins
    • Yang K, Zhang L, Xu T, Heroux A, Zhao R. 2008. Crystal structure of the -finger domain of Prp8 reveals analogy to ribosomal proteins. Proc Natl Acad Sci 105: 13817-13822.
    • (2008) Proc Natl Acad Sci , vol.105 , pp. 13817-13822
    • Yang, K.1    Zhang, L.2    Xu, T.3    Heroux, A.4    Zhao, R.5
  • 70
    • 0035187881 scopus 로고    scopus 로고
    • Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56
    • Zhang M, Green MR. 2001. Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56. Genes Dev 15: 30-35.
    • (2001) Genes Dev , vol.15 , pp. 30-35
    • Zhang, M.1    Green, M.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.