Archaeal Hel308 Domain V Couples DNA Binding to ATP Hydrolysis and Positions DNA for Unwinding Over the Helicase Ratchet

Journal of Molecular Biology

Volumn 374, Issue 5, 2007, Pages 1139-1144

  Woodman, Isabel L ^a   Briggs, Geoffrey S ^a   Bolt, Edward L ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

archaea; ATPase; DNA repair; Hel308; helicase

Indexed keywords

ADENOSINE TRIPHOSPHATE; BACTERIAL DNA; HELICASE; SINGLE STRANDED DNA;

ARCHAEOGLOBUS FULGIDUS; ARTICLE; BACTERIAL GENOME; DNA PROTEIN COMPLEX; DNA REPAIR; ENZYME ACTIVITY; GENETIC STABILITY; NONHUMAN; PARALOGY; PRIORITY JOURNAL;

ARCHAEA; ARCHAEOGLOBUS FULGIDUS; EUKARYOTA;

EID: 36248999467     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.10.004     Document Type: Article

References (12)

1. Fujikane R., Shinagawa H., and Ishino Y. The archaeal Hjm helicase has recQ-like functions, and may be involved in repair of stalled replication fork. Genes to Cells 11 (2006) 99-110
2. Guy C.P., and Bolt E.L. Archaeal Hel308 helicase targets replication forks in vivo and in vitro and unwinds lagging strands. Nucleic Acids Res. 33 (2005) 3678-3690
3. Johnson-Schlitz D.M., Flores C., and Engels W. Multiple-pathway analysis of double-strand break repair mutations in Drosophila. PLoS Genet. 3 (2007) 544-558
4. Laurencon A., Orme C.M., Peters H.K., Boulton C.L., Vladar E.K., Langley S.A., et al. A large-scale screen for mutagen-sensitive loci in Drosophila. Genetics 167 (2004) 217-231
5. Yoshimura M., Kohzaki M., Nakamura J., Asagoshi K., Sonoda E., Hou E., et al. Vertebrate POLQ and PolBeta cooperate in base excision repair of oxidative DNA damage. Mol. Cell 24 (2006) 115-125
6. Boyd J.B., Sakaguchi K., and Harris P.V. mus308 mutants of Drosophila exhibit hypersensitivity to DNA cross-linking agents and are defective in a deoxyribonuclease. Genetics 125 (1990) 813-819
7. Seki M., Marini F., and Wood R.D. POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells. Nucleic Acids Res. 31 (2003) 6117-6126
8. Shima N., Munroe R.J., and Schimenti J.C. The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm. Mol. Cell. Biol. 24 (2004) 10381-10389
9. Marini F., and Wood R. A human DNA helicase homologous to the DNA crosslink sensitivity protein mus308. J. Biol. Chem. 277 (2001) 8716-8723
10. Fujikane R., Komori K., Shinagawa H., and Ishino Y. Identification of a novel helicase activity unwinding branched DNAs from the hyperthermophilic archaeon, Pyrococcus furiosus. J. Biol. Chem. 280 (2005) 12351-12358
11. Buttner K., Nehring S., and Hopfner K.P. Structural basis for DNA duplex separation by a superfamily-2 helicase. Nat. Struct. Mol. Biol. 14 (2007) 647-652
12. Zheng W., and Doniach S. A comparative study of motor protein motions by using a simple elastic-network model. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 13253-13258