메뉴 건너뛰기




Volumn 55, Issue 1, 2014, Pages 87-95

Behavioral phenotyping of Nestin-Cre mice: Implications for genetic mouse models of psychiatric disorders

Author keywords

Anxiety; Cre loxP system; Fear conditioning; Mouse model

Indexed keywords

CRE RECOMBINASE; NESTIN; INTEGRASE; NES PROTEIN, MOUSE;

EID: 84901408369     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2014.04.002     Document Type: Article
Times cited : (68)

References (65)
  • 1
    • 84867217874 scopus 로고    scopus 로고
    • Are we getting closer to valid translational models for major depression?
    • Berton O., Hahn C.G., Thase M.E. Are we getting closer to valid translational models for major depression?. Science 2012, 338:75-79.
    • (2012) Science , vol.338 , pp. 75-79
    • Berton, O.1    Hahn, C.G.2    Thase, M.E.3
  • 2
    • 31444441701 scopus 로고    scopus 로고
    • New approaches to antidepressant drug discovery: beyond monoamines
    • Berton O., Nestler E.J. New approaches to antidepressant drug discovery: beyond monoamines. Nat Rev Neurosci 2006, 7:137-151.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 137-151
    • Berton, O.1    Nestler, E.J.2
  • 3
    • 84891788593 scopus 로고    scopus 로고
    • The Mouse Genome Database: integration of and access to knowledge about the laboratory mouse
    • Blake J.A., Bult C.J., Eppig J.T., Kadin J.A., Richardson J.E. The Mouse Genome Database: integration of and access to knowledge about the laboratory mouse. Nucleic Acids Res 2014, 42:D810-D817.
    • (2014) Nucleic Acids Res , vol.42
    • Blake, J.A.1    Bult, C.J.2    Eppig, J.T.3    Kadin, J.A.4    Richardson, J.E.5
  • 5
    • 0034891977 scopus 로고    scopus 로고
    • Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies
    • Braff D.L., Geyer M.A., Swerdlow N.R. Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacol Berl 2001, 156:234-258.
    • (2001) Psychopharmacol Berl , vol.156 , pp. 234-258
    • Braff, D.L.1    Geyer, M.A.2    Swerdlow, N.R.3
  • 6
    • 0346503889 scopus 로고    scopus 로고
    • Talking about a revolution: the impact of site-specific recombinases on genetic analyses in mice
    • Branda C.S., Dymecki S.M. Talking about a revolution: the impact of site-specific recombinases on genetic analyses in mice. Dev Cell 2004, 6:7-28.
    • (2004) Dev Cell , vol.6 , pp. 7-28
    • Branda, C.S.1    Dymecki, S.M.2
  • 7
    • 78650071301 scopus 로고    scopus 로고
    • Combined neural inactivation of suppressor of cytokine signaling-3 and protein-tyrosine phosphatase-1B reveals additive, synergistic, and factor-specific roles in the regulation of body energy balance
    • Briancon N., McNay D.E., Maratos-Flier E., Flier J.S. Combined neural inactivation of suppressor of cytokine signaling-3 and protein-tyrosine phosphatase-1B reveals additive, synergistic, and factor-specific roles in the regulation of body energy balance. Diabetes 2010, 59:3074-3084.
    • (2010) Diabetes , vol.59 , pp. 3074-3084
    • Briancon, N.1    McNay, D.E.2    Maratos-Flier, E.3    Flier, J.S.4
  • 8
    • 0033523043 scopus 로고    scopus 로고
    • Genetics of mouse behavior: interactions with laboratory environment
    • Crabbe J.C., Wahlsten D., Dudek B.C. Genetics of mouse behavior: interactions with laboratory environment. Science 1999, 284:1670-1672.
    • (1999) Science , vol.284 , pp. 1670-1672
    • Crabbe, J.C.1    Wahlsten, D.2    Dudek, B.C.3
  • 9
    • 40849132907 scopus 로고    scopus 로고
    • Behavioral phenotyping strategies for mutant mice
    • Crawley J.N. Behavioral phenotyping strategies for mutant mice. Neuron 2008, 57:809-818.
    • (2008) Neuron , vol.57 , pp. 809-818
    • Crawley, J.N.1
  • 10
    • 26044460006 scopus 로고    scopus 로고
    • The ascent of mouse: advances in modelling human depression and anxiety
    • Cryan J.F., Holmes A. The ascent of mouse: advances in modelling human depression and anxiety. Nat Rev Drug Discov 2005, 4:775-790.
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 775-790
    • Cryan, J.F.1    Holmes, A.2
  • 11
    • 84885601005 scopus 로고    scopus 로고
    • Targeted mutagenesis tools for modelling psychiatric disorders
    • Deussing J.M. Targeted mutagenesis tools for modelling psychiatric disorders. Cell Tissue Res 2013, 354:9-25.
    • (2013) Cell Tissue Res , vol.354 , pp. 9-25
    • Deussing, J.M.1
  • 12
    • 0033232518 scopus 로고    scopus 로고
    • Dopamine D4 receptor-knock-out mice exhibit reduced exploration of novel stimuli
    • Dulawa S.C., Grandy D.K., Low M.J., Paulus M.P., Geyer M.A. Dopamine D4 receptor-knock-out mice exhibit reduced exploration of novel stimuli. J.Neurosci 1999, 19:9550-9556.
    • (1999) J.Neurosci , vol.19 , pp. 9550-9556
    • Dulawa, S.C.1    Grandy, D.K.2    Low, M.J.3    Paulus, M.P.4    Geyer, M.A.5
  • 13
    • 29344455221 scopus 로고    scopus 로고
    • Nestin-expressing cells and their relationship to mitotically active cells in the subventricular zones of the adult rat
    • Ernst C., Christie B.R. Nestin-expressing cells and their relationship to mitotically active cells in the subventricular zones of the adult rat. Eur J Neurosci 2005, 22:3059-3066.
    • (2005) Eur J Neurosci , vol.22 , pp. 3059-3066
    • Ernst, C.1    Christie, B.R.2
  • 16
    • 77955405459 scopus 로고    scopus 로고
    • Nestin-Cre mice are affected by hypopituitarism, which is not due to significant activity of the transgene in the pituitary gland
    • Galichet C., Lovell-Badge R., Rizzoti K. Nestin-Cre mice are affected by hypopituitarism, which is not due to significant activity of the transgene in the pituitary gland. PLoS One 2010, 5:e11443.
    • (2010) PLoS One , vol.5
    • Galichet, C.1    Lovell-Badge, R.2    Rizzoti, K.3
  • 17
    • 77956185062 scopus 로고    scopus 로고
    • Anovel pathway regulates memory and plasticity via SIRT1 and miR-134
    • Gao J., Wang W.Y., Mao Y.W., Graff J., Guan J.S., Pan L., et al. Anovel pathway regulates memory and plasticity via SIRT1 and miR-134. Nature 2010, 466:1105-1109.
    • (2010) Nature , vol.466 , pp. 1105-1109
    • Gao, J.1    Wang, W.Y.2    Mao, Y.W.3    Graff, J.4    Guan, J.S.5    Pan, L.6
  • 18
    • 33847658304 scopus 로고    scopus 로고
    • Conditional gene targeting in the mouse nervous system: insights into brain function and diseases
    • Gaveriaux-Ruff C., Kieffer B.L. Conditional gene targeting in the mouse nervous system: insights into brain function and diseases. Pharmacol Ther 2007, 113:619-634.
    • (2007) Pharmacol Ther , vol.113 , pp. 619-634
    • Gaveriaux-Ruff, C.1    Kieffer, B.L.2
  • 19
    • 84887008084 scopus 로고    scopus 로고
    • GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits
    • Gerfen C.R., Paletzki R., Heintz N. GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits. Neuron 2013, 80:1368-1383.
    • (2013) Neuron , vol.80 , pp. 1368-1383
    • Gerfen, C.R.1    Paletzki, R.2    Heintz, N.3
  • 20
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: etymology and strategic intentions
    • Gottesman, Gould T.D. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003, 160:636-645.
    • (2003) Am J Psychiatry , vol.160 , pp. 636-645
    • Gottesman1    Gould, T.D.2
  • 21
    • 0028059099 scopus 로고
    • Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
    • Gu H., Marth J.D., Orban P.C., Mossmann H., Rajewsky K. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science 1994, 265:103-106.
    • (1994) Science , vol.265 , pp. 103-106
    • Gu, H.1    Marth, J.D.2    Orban, P.C.3    Mossmann, H.4    Rajewsky, K.5
  • 22
    • 84879868603 scopus 로고    scopus 로고
    • Metabolic pitfalls of CNS Cre-based technology
    • Harno E., Cottrell E.C., White A. Metabolic pitfalls of CNS Cre-based technology. Cell Metab 2013, 18:21-28.
    • (2013) Cell Metab , vol.18 , pp. 21-28
    • Harno, E.1    Cottrell, E.C.2    White, A.3
  • 23
    • 84869884499 scopus 로고    scopus 로고
    • Fkbp52 heterozygosity alters behavioral, endocrine and neurogenetic parameters under basal and chronic stress conditions in mice
    • Hartmann J., Wagner K.V., Dedic N., Marinescu D., Scharf S.H., Wang X.D., et al. Fkbp52 heterozygosity alters behavioral, endocrine and neurogenetic parameters under basal and chronic stress conditions in mice. Psychoneuroendocrinology 2012, 37:2009-2021.
    • (2012) Psychoneuroendocrinology , vol.37 , pp. 2009-2021
    • Hartmann, J.1    Wagner, K.V.2    Dedic, N.3    Marinescu, D.4    Scharf, S.H.5    Wang, X.D.6
  • 25
    • 77955622258 scopus 로고    scopus 로고
    • Inducible activation of Cre recombinase in adult mice causes gastric epithelial atrophy, metaplasia, and regenerative changes in the absence of "floxed" alleles
    • Huh W.J., Mysorekar I.U., Mills J.C. Inducible activation of Cre recombinase in adult mice causes gastric epithelial atrophy, metaplasia, and regenerative changes in the absence of "floxed" alleles. Am J Physiol Gastrointest Liver Physiol 2010, 299:G368-G380.
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.299
    • Huh, W.J.1    Mysorekar, I.U.2    Mills, J.C.3
  • 26
    • 84896884418 scopus 로고    scopus 로고
    • Cre recombinase induces DNA damage and tetraploidy in the absence of LoxP sites
    • Janbandhu V.C., Moik D., Fassler R. Cre recombinase induces DNA damage and tetraploidy in the absence of LoxP sites. Cell Cycle 2014, 13:462-470.
    • (2014) Cell Cycle , vol.13 , pp. 462-470
    • Janbandhu, V.C.1    Moik, D.2    Fassler, R.3
  • 28
    • 10044272343 scopus 로고    scopus 로고
    • Nonassociative learning processes determine expression and extinction of conditioned fear in mice
    • Kamprath K., Wotjak C.T. Nonassociative learning processes determine expression and extinction of conditioned fear in mice. Learn Memory 2004, 11:770-786.
    • (2004) Learn Memory , vol.11 , pp. 770-786
    • Kamprath, K.1    Wotjak, C.T.2
  • 29
    • 84896706746 scopus 로고    scopus 로고
    • Development of mice with brain-specific deletion of floxed glud1 (glutamate dehydrogenase 1) using cre recombinase driven by the nestin promoter
    • Karaca M., Maechler P. Development of mice with brain-specific deletion of floxed glud1 (glutamate dehydrogenase 1) using cre recombinase driven by the nestin promoter. Neurochem Res 2014, 39:456-459.
    • (2014) Neurochem Res , vol.39 , pp. 456-459
    • Karaca, M.1    Maechler, P.2
  • 30
    • 0035118134 scopus 로고    scopus 로고
    • Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells
    • Kawaguchi A., Miyata T., Sawamoto K., Takashita N., Murayama A., Akamatsu W., et al. Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells. Mol Cell Neurosci 2001, 17:259-273.
    • (2001) Mol Cell Neurosci , vol.17 , pp. 259-273
    • Kawaguchi, A.1    Miyata, T.2    Sawamoto, K.3    Takashita, N.4    Murayama, A.5    Akamatsu, W.6
  • 33
    • 0032535354 scopus 로고    scopus 로고
    • Fear and the brain: where have we been, and where are we going?
    • LeDoux J. Fear and the brain: where have we been, and where are we going?. Biol Psychiatry 1998, 44:1229-1238.
    • (1998) Biol Psychiatry , vol.44 , pp. 1229-1238
    • LeDoux, J.1
  • 34
  • 35
    • 32544454992 scopus 로고    scopus 로고
    • Genetics of affective and anxiety disorders
    • Leonardo E.D., Hen R. Genetics of affective and anxiety disorders. Annu Rev Psychol 2006, 57:117-137.
    • (2006) Annu Rev Psychol , vol.57 , pp. 117-137
    • Leonardo, E.D.1    Hen, R.2
  • 36
    • 84866516735 scopus 로고    scopus 로고
    • MEK is a key regulator of gliogenesis in the developing brain
    • Li X., Newbern J.M., Wu Y., Morgan-Smith M., Zhong J., Charron J., et al. MEK is a key regulator of gliogenesis in the developing brain. Neuron 2012, 75:1035-1050.
    • (2012) Neuron , vol.75 , pp. 1035-1050
    • Li, X.1    Newbern, J.M.2    Wu, Y.3    Morgan-Smith, M.4    Zhong, J.5    Charron, J.6
  • 38
    • 0030980110 scopus 로고    scopus 로고
    • An evolutionarily conserved region in the second intron of the human nestin gene directs gene expression to CNS progenitor cells and to early neural crest cells
    • Lothian C., Lendahl U. An evolutionarily conserved region in the second intron of the human nestin gene directs gene expression to CNS progenitor cells and to early neural crest cells. Eur J Neurosci 1997, 9:452-462.
    • (1997) Eur J Neurosci , vol.9 , pp. 452-462
    • Lothian, C.1    Lendahl, U.2
  • 39
    • 54249132082 scopus 로고    scopus 로고
    • Conditional CRH overexpressing mice: an animal model for stress-elicited pathologies and treatments that target the central CRH system
    • Lu A., Steiner M.A., Whittle N., Vogl A.M., Walser S.M., Ableitner M., et al. Conditional CRH overexpressing mice: an animal model for stress-elicited pathologies and treatments that target the central CRH system. Mol Psychiatry 2008, 13:989.
    • (2008) Mol Psychiatry , vol.13 , pp. 989
    • Lu, A.1    Steiner, M.A.2    Whittle, N.3    Vogl, A.M.4    Walser, S.M.5    Ableitner, M.6
  • 40
    • 77954855825 scopus 로고    scopus 로고
    • SIRT1 is essential for normal cognitive function and synaptic plasticity
    • Michan S., Li Y., Chou M.M., Parrella E., Ge H., Long J.M., et al. SIRT1 is essential for normal cognitive function and synaptic plasticity. JNeurosci 2010, 30:9695-9707.
    • (2010) JNeurosci , vol.30 , pp. 9695-9707
    • Michan, S.1    Li, Y.2    Chou, M.M.3    Parrella, E.4    Ge, H.5    Long, J.M.6
  • 42
    • 84856472879 scopus 로고    scopus 로고
    • Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy
    • Millan M.J., Agid Y., Brune M., Bullmore E.T., Carter C.S., Clayton N.S., et al. Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy. Nat Rev Drug Discov 2012, 11:141-168.
    • (2012) Nat Rev Drug Discov , vol.11 , pp. 141-168
    • Millan, M.J.1    Agid, Y.2    Brune, M.3    Bullmore, E.T.4    Carter, C.S.5    Clayton, N.S.6
  • 43
    • 40749130480 scopus 로고    scopus 로고
    • Galpha12/Galpha13 deficiency causes localized overmigration of neurons in the developing cerebral and cerebellar cortices
    • Moers A., Nurnberg A., Goebbels S., Wettschureck N., Offermanns S. Galpha12/Galpha13 deficiency causes localized overmigration of neurons in the developing cerebral and cerebellar cortices. Mol Cell Biol 2008, 28:1480-1488.
    • (2008) Mol Cell Biol , vol.28 , pp. 1480-1488
    • Moers, A.1    Nurnberg, A.2    Goebbels, S.3    Wettschureck, N.4    Offermanns, S.5
  • 44
    • 12744261491 scopus 로고    scopus 로고
    • Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome
    • Moretti P., Bouwknecht J.A., Teague R., Paylor R., Zoghbi H.Y. Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome. Hum Mol Genet. 2005, 14:205-220.
    • (2005) Hum Mol Genet. , vol.14 , pp. 205-220
    • Moretti, P.1    Bouwknecht, J.A.2    Teague, R.3    Paylor, R.4    Zoghbi, H.Y.5
  • 45
    • 4644373224 scopus 로고    scopus 로고
    • Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice
    • Moy S.S., Nadler J.J., Perez A., Barbaro R.P., Johns J.M., Magnuson T.R., et al. Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice. Genes Brain Behav 2004, 3:287-302.
    • (2004) Genes Brain Behav , vol.3 , pp. 287-302
    • Moy, S.S.1    Nadler, J.J.2    Perez, A.3    Barbaro, R.P.4    Johns, J.M.5    Magnuson, T.R.6
  • 46
    • 4644333560 scopus 로고    scopus 로고
    • Automated apparatus for quantitation of social approach behaviors in mice
    • Nadler J.J., Moy S.S., Dold G., Trang D., Simmons N., Perez A., et al. Automated apparatus for quantitation of social approach behaviors in mice. Genes Brain Behav 2004, 3:303-314.
    • (2004) Genes Brain Behav , vol.3 , pp. 303-314
    • Nadler, J.J.1    Moy, S.S.2    Dold, G.3    Trang, D.4    Simmons, N.5    Perez, A.6
  • 47
    • 0034059140 scopus 로고    scopus 로고
    • Cre recombinase: the universal reagent for genome tailoring
    • Nagy A. Cre recombinase: the universal reagent for genome tailoring. Genesis 2000, 26:99-109.
    • (2000) Genesis , vol.26 , pp. 99-109
    • Nagy, A.1
  • 48
    • 38549123928 scopus 로고    scopus 로고
    • Cre activity causes widespread apoptosis and lethal anemia during embryonic development
    • Naiche L.A., Papaioannou V.E. Cre activity causes widespread apoptosis and lethal anemia during embryonic development. Genesis 2007, 45:768-775.
    • (2007) Genesis , vol.45 , pp. 768-775
    • Naiche, L.A.1    Papaioannou, V.E.2
  • 49
    • 77957273984 scopus 로고    scopus 로고
    • Animal models of neuropsychiatric disorders
    • Nestler E.J., Hyman S.E. Animal models of neuropsychiatric disorders. Nat Neurosci 2010, 13:1161-1169.
    • (2010) Nat Neurosci , vol.13 , pp. 1161-1169
    • Nestler, E.J.1    Hyman, S.E.2
  • 50
    • 84860522792 scopus 로고    scopus 로고
    • Id proteins synchronize stemness and anchorage to the niche of neural stem cells
    • Niola F., Zhao X., Singh D., Castano A., Sullivan R., Lauria M., et al. Id proteins synchronize stemness and anchorage to the niche of neural stem cells. Nat Cell Biol 2012, 14:477-487.
    • (2012) Nat Cell Biol , vol.14 , pp. 477-487
    • Niola, F.1    Zhao, X.2    Singh, D.3    Castano, A.4    Sullivan, R.5    Lauria, M.6
  • 51
    • 84880051372 scopus 로고    scopus 로고
    • Animal models of depression
    • CRC Press, F. Lopez-Munoz, C. Alamo (Eds.)
    • Refojo D., Deussing J.M. Animal models of depression. Neurobiology of depression 2012, 1-25. CRC Press. F. Lopez-Munoz, C. Alamo (Eds.).
    • (2012) Neurobiology of depression , pp. 1-25
    • Refojo, D.1    Deussing, J.M.2
  • 52
    • 70449372203 scopus 로고    scopus 로고
    • CRH signaling. Molecular specificity for drug targeting in the CNS
    • Refojo D., Holsboer F. CRH signaling. Molecular specificity for drug targeting in the CNS. Ann N Y Acad Sci 2009, 1179:106-119.
    • (2009) Ann N Y Acad Sci , vol.1179 , pp. 106-119
    • Refojo, D.1    Holsboer, F.2
  • 53
    • 80053365601 scopus 로고    scopus 로고
    • Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1
    • Refojo D., Schweizer M., Kuehne C., Ehrenberg S., Thoeringer C., Vogl A.M., et al. Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1. Science 2011, 333:1903-1907.
    • (2011) Science , vol.333 , pp. 1903-1907
    • Refojo, D.1    Schweizer, M.2    Kuehne, C.3    Ehrenberg, S.4    Thoeringer, C.5    Vogl, A.M.6
  • 54
    • 0024041732 scopus 로고
    • Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1
    • Sauer B., Henderson N. Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1. Proc Natl Acad Sci U.S.A 1988, 85:5166-5170.
    • (1988) Proc Natl Acad Sci U.S.A , vol.85 , pp. 5166-5170
    • Sauer, B.1    Henderson, N.2
  • 56
    • 34250694086 scopus 로고    scopus 로고
    • Vagaries of conditional gene targeting
    • Schmidt-Supprian M., Rajewsky K. Vagaries of conditional gene targeting. Nat Immunol 2007, 8:665-668.
    • (2007) Nat Immunol , vol.8 , pp. 665-668
    • Schmidt-Supprian, M.1    Rajewsky, K.2
  • 57
    • 0021990491 scopus 로고
    • The tail suspension test: a new method for screening antidepressants in mice
    • Steru L., Chermat R., Thierry B., Simon P. The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacol Berl 1985, 85:367-370.
    • (1985) Psychopharmacol Berl , vol.85 , pp. 367-370
    • Steru, L.1    Chermat, R.2    Thierry, B.3    Simon, P.4
  • 58
    • 84876967280 scopus 로고    scopus 로고
    • Reduction of the cholesterol sensor SCAP in the brains of mice causes impaired synaptic transmission and altered cognitive function
    • Suzuki R., Ferris H.A., Chee M.J., Maratos-Flier E., Kahn C.R. Reduction of the cholesterol sensor SCAP in the brains of mice causes impaired synaptic transmission and altered cognitive function. PLoS Biol 2013, 11:e1001532.
    • (2013) PLoS Biol , vol.11
    • Suzuki, R.1    Ferris, H.A.2    Chee, M.J.3    Maratos-Flier, E.4    Kahn, C.R.5
  • 59
    • 80053128156 scopus 로고    scopus 로고
    • Aresource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex
    • Taniguchi H., He M., Wu P., Kim S., Paik R., Sugino K., et al. Aresource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex. Neuron 2011, 71:995-1013.
    • (2011) Neuron , vol.71 , pp. 995-1013
    • Taniguchi, H.1    He, M.2    Wu, P.3    Kim, S.4    Paik, R.5    Sugino, K.6
  • 60
    • 0343673926 scopus 로고    scopus 로고
    • Dissection of behavior and psychiatric disorders using the mouse as a model
    • Tarantino L.M., Bucan M. Dissection of behavior and psychiatric disorders using the mouse as a model. Hum Mol Genet 2000, 9:953-965.
    • (2000) Hum Mol Genet , vol.9 , pp. 953-965
    • Tarantino, L.M.1    Bucan, M.2
  • 61
    • 84860239954 scopus 로고    scopus 로고
    • Evidence for baseline retinal pigment epithelium pathology in the Trp1-Cre mouse
    • Thanos A., Morizane Y., Murakami Y., Giani A., Mantopoulos D., Kayama M., et al. Evidence for baseline retinal pigment epithelium pathology in the Trp1-Cre mouse. Am J Pathol 2012, 180:1917-1927.
    • (2012) Am J Pathol , vol.180 , pp. 1917-1927
    • Thanos, A.1    Morizane, Y.2    Murakami, Y.3    Giani, A.4    Mantopoulos, D.5    Kayama, M.6
  • 62
    • 0032842478 scopus 로고    scopus 로고
    • Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety
    • Tronche F., Kellendonk C., Kretz O., Gass P., Anlag K., Orban P.C., et al. Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety. Nat Genet 1999, 23:99-103.
    • (1999) Nat Genet , vol.23 , pp. 99-103
    • Tronche, F.1    Kellendonk, C.2    Kretz, O.3    Gass, P.4    Anlag, K.5    Orban, P.C.6
  • 63
    • 78650424375 scopus 로고    scopus 로고
    • Neuronal Abelson helper integration site-1 (Ahi1) deficiency in mice alters TrkB signaling with a depressive phenotype
    • Xu X., Yang H., Lin Y.F., Li X., Cape A., Ressler K.J., et al. Neuronal Abelson helper integration site-1 (Ahi1) deficiency in mice alters TrkB signaling with a depressive phenotype. Proc Natl Acad Sci U.S.A 2010, 107:19126-19131.
    • (2010) Proc Natl Acad Sci U.S.A , vol.107 , pp. 19126-19131
    • Xu, X.1    Yang, H.2    Lin, Y.F.3    Li, X.4    Cape, A.5    Ressler, K.J.6
  • 64
    • 39149099035 scopus 로고    scopus 로고
    • Arole for adult TLX-positive neural stem cells in learning and behaviour
    • Zhang C.L., Zou Y., He W., Gage F.H., Evans R.M. Arole for adult TLX-positive neural stem cells in learning and behaviour. Nature 2008, 451:1004-1007.
    • (2008) Nature , vol.451 , pp. 1004-1007
    • Zhang, C.L.1    Zou, Y.2    He, W.3    Gage, F.H.4    Evans, R.M.5
  • 65
    • 44649177751 scopus 로고    scopus 로고
    • Central nervous system-specific knockout of steroidogenic factor 1 results in increased anxiety-like behavior
    • Zhao L., Kim K.W., Ikeda Y., Anderson K.K., Beck L., Chase S., et al. Central nervous system-specific knockout of steroidogenic factor 1 results in increased anxiety-like behavior. Mol Endocrinol 2008, 22:1403-1415.
    • (2008) Mol Endocrinol , vol.22 , pp. 1403-1415
    • Zhao, L.1    Kim, K.W.2    Ikeda, Y.3    Anderson, K.K.4    Beck, L.5    Chase, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.