메뉴 건너뛰기




Volumn 75, Issue 6, 2012, Pages 1035-1050

MEK Is a Key Regulator of Gliogenesis in the Developing Brain

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETV5; UNCLASSIFIED DRUG;

EID: 84866516735     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2012.08.031     Document Type: Article
Times cited : (133)

References (70)
  • 1
    • 25844504298 scopus 로고    scopus 로고
    • Signaling between glia and neurons: focus on synaptic plasticity
    • Allen N.J., Barres B.A. Signaling between glia and neurons: focus on synaptic plasticity. Curr. Opin. Neurobiol. 2005, 15:542-548.
    • (2005) Curr. Opin. Neurobiol. , vol.15 , pp. 542-548
    • Allen, N.J.1    Barres, B.A.2
  • 2
    • 58149274696 scopus 로고    scopus 로고
    • Genetic lineage tracing defines distinct neurogenic and gliogenic stages of ventral telencephalic radial glial development
    • Anthony T.E., Heintz N. Genetic lineage tracing defines distinct neurogenic and gliogenic stages of ventral telencephalic radial glial development. Neural Dev. 2008, 3:30.
    • (2008) Neural Dev. , vol.3 , pp. 30
    • Anthony, T.E.1    Heintz, N.2
  • 3
    • 0345119182 scopus 로고    scopus 로고
    • Neural tissue in ascidian embryos is induced by FGF9/16/20, acting via a combination of maternal GATA and Ets transcription factors
    • Bertrand V., Hudson C., Caillol D., Popovici C., Lemaire P. Neural tissue in ascidian embryos is induced by FGF9/16/20, acting via a combination of maternal GATA and Ets transcription factors. Cell 2003, 115:615-627.
    • (2003) Cell , vol.115 , pp. 615-627
    • Bertrand, V.1    Hudson, C.2    Caillol, D.3    Popovici, C.4    Lemaire, P.5
  • 6
    • 79952435349 scopus 로고    scopus 로고
    • Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases
    • Cargnello M., Roux P.P. Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases. Microbiol. Mol. Biol. Rev. 2011, 75:50-83.
    • (2011) Microbiol. Mol. Biol. Rev. , vol.75 , pp. 50-83
    • Cargnello, M.1    Roux, P.P.2
  • 9
    • 38449112796 scopus 로고    scopus 로고
    • Neurons or glia? Can SHP2 know it all?
    • Coskun V., Zhao J., Sun Y.E. Neurons or glia? Can SHP2 know it all?. Sci. STKE 2007, 2007:pe58.
    • (2007) Sci. STKE , vol.2007
    • Coskun, V.1    Zhao, J.2    Sun, Y.E.3
  • 10
    • 33846193741 scopus 로고    scopus 로고
    • Shp2-mediated molecular signaling in control of embryonic stem cell self-renewal and differentiation
    • Feng G.S. Shp2-mediated molecular signaling in control of embryonic stem cell self-renewal and differentiation. Cell Res. 2007, 17:37-41.
    • (2007) Cell Res. , vol.17 , pp. 37-41
    • Feng, G.S.1
  • 13
    • 78751509692 scopus 로고    scopus 로고
    • The ERK2 mitogen-activated protein kinase regulates the timing of oligodendrocyte differentiation
    • Fyffe-Maricich S.L., Karlo J.C., Landreth G.E., Miller R.H. The ERK2 mitogen-activated protein kinase regulates the timing of oligodendrocyte differentiation. J. Neurosci. 2011, 31:843-850.
    • (2011) J. Neurosci. , vol.31 , pp. 843-850
    • Fyffe-Maricich, S.L.1    Karlo, J.C.2    Landreth, G.E.3    Miller, R.H.4
  • 14
    • 0036304110 scopus 로고    scopus 로고
    • The role of notch in promoting glial and neural stem cell fates
    • Gaiano N., Fishell G. The role of notch in promoting glial and neural stem cell fates. Annu. Rev. Neurosci. 2002, 25:471-490.
    • (2002) Annu. Rev. Neurosci. , vol.25 , pp. 471-490
    • Gaiano, N.1    Fishell, G.2
  • 17
    • 84859918868 scopus 로고    scopus 로고
    • Local generation of glia is a major astrocyte source in postnatal cortex
    • Ge W.P., Miyawaki A., Gage F.H., Jan Y.N., Jan L.Y. Local generation of glia is a major astrocyte source in postnatal cortex. Nature 2012, 484:376-380.
    • (2012) Nature , vol.484 , pp. 376-380
    • Ge, W.P.1    Miyawaki, A.2    Gage, F.H.3    Jan, Y.N.4    Jan, L.Y.5
  • 18
    • 80051904826 scopus 로고    scopus 로고
    • From cradle to grave: the multiple roles of fibroblast growth factors in neural development
    • Guillemot F., Zimmer C. From cradle to grave: the multiple roles of fibroblast growth factors in neural development. Neuron 2011, 71:574-588.
    • (2011) Neuron , vol.71 , pp. 574-588
    • Guillemot, F.1    Zimmer, C.2
  • 19
    • 0034163411 scopus 로고    scopus 로고
    • The Ets domain transcription factor Erm distinguishes rat satellite glia from Schwann cells and is regulated in satellite cells by neuregulin signaling
    • Hagedorn L., Paratore C., Brugnoli G., Baert J.L., Mercader N., Suter U., Sommer L. The Ets domain transcription factor Erm distinguishes rat satellite glia from Schwann cells and is regulated in satellite cells by neuregulin signaling. Dev. Biol. 2000, 219:44-58.
    • (2000) Dev. Biol. , vol.219 , pp. 44-58
    • Hagedorn, L.1    Paratore, C.2    Brugnoli, G.3    Baert, J.L.4    Mercader, N.5    Suter, U.6    Sommer, L.7
  • 22
    • 34848830908 scopus 로고    scopus 로고
    • Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms
    • Hegedus B., Dasgupta B., Shin J.E., Emnett R.J., Hart-Mahon E.K., Elghazi L., Bernal-Mizrachi E., Gutmann D.H. Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms. Cell Stem Cell 2007, 1:443-457.
    • (2007) Cell Stem Cell , vol.1 , pp. 443-457
    • Hegedus, B.1    Dasgupta, B.2    Shin, J.E.3    Emnett, R.J.4    Hart-Mahon, E.K.5    Elghazi, L.6    Bernal-Mizrachi, E.7    Gutmann, D.H.8
  • 23
    • 77957120399 scopus 로고    scopus 로고
    • ERK1 and ERK2 are required for radial glial maintenance and cortical lamination
    • Imamura O., Pagès G., Pouysségur J., Endo S., Takishima K. ERK1 and ERK2 are required for radial glial maintenance and cortical lamination. Genes Cells 2010, 15:1072-1088.
    • (2010) Genes Cells , vol.15 , pp. 1072-1088
    • Imamura, O.1    Pagès, G.2    Pouysségur, J.3    Endo, S.4    Takishima, K.5
  • 24
    • 84862900786 scopus 로고    scopus 로고
    • ERK1/ERK2 MAPK signaling is required to increase myelin thickness independent of oligodendrocyte differentiation and initiation of myelination
    • Ishii A., Fyffe-Maricich S.L., Furusho M., Miller R.H., Bansal R. ERK1/ERK2 MAPK signaling is required to increase myelin thickness independent of oligodendrocyte differentiation and initiation of myelination. J. Neurosci. 2012, 32:8855-8864.
    • (2012) J. Neurosci. , vol.32 , pp. 8855-8864
    • Ishii, A.1    Fyffe-Maricich, S.L.2    Furusho, M.3    Miller, R.H.4    Bansal, R.5
  • 25
    • 0034594368 scopus 로고    scopus 로고
    • The midline glia of Drosophila: a molecular genetic model for the developmental functions of glia
    • Jacobs J.R. The midline glia of Drosophila: a molecular genetic model for the developmental functions of glia. Prog. Neurobiol. 2000, 62:475-508.
    • (2000) Prog. Neurobiol. , vol.62 , pp. 475-508
    • Jacobs, J.R.1
  • 26
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • Johnson G.L., Lapadat R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002, 298:1911-1912.
    • (2002) Science , vol.298 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 27
    • 34748824069 scopus 로고    scopus 로고
    • Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality
    • Ke Y., Zhang E.E., Hagihara K., Wu D., Pang Y., Klein R., Curran T., Ranscht B., Feng G.S. Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality. Mol. Cell. Biol. 2007, 27:6706-6717.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 6706-6717
    • Ke, Y.1    Zhang, E.E.2    Hagihara, K.3    Wu, D.4    Pang, Y.5    Klein, R.6    Curran, T.7    Ranscht, B.8    Feng, G.S.9
  • 28
    • 38349041625 scopus 로고    scopus 로고
    • Ets-1 regulates radial glia formation during vertebrate embryogenesis
    • Kiyota T., Kato A., Kato Y. Ets-1 regulates radial glia formation during vertebrate embryogenesis. Organogenesis 2007, 3:93-101.
    • (2007) Organogenesis , vol.3 , pp. 93-101
    • Kiyota, T.1    Kato, A.2    Kato, Y.3
  • 29
    • 0028206040 scopus 로고
    • The Ets transcription factors encoded by the Drosophila gene pointed direct glial cell differentiation in the embryonic CNS
    • Klaes A., Menne T., Stollewerk A., Scholz H., Klämbt C. The Ets transcription factors encoded by the Drosophila gene pointed direct glial cell differentiation in the embryonic CNS. Cell 1994, 78:149-160.
    • (1994) Cell , vol.78 , pp. 149-160
    • Klaes, A.1    Menne, T.2    Stollewerk, A.3    Scholz, H.4    Klämbt, C.5
  • 31
    • 67651036549 scopus 로고    scopus 로고
    • The glial nature of embryonic and adult neural stem cells
    • Kriegstein A., Alvarez-Buylla A. The glial nature of embryonic and adult neural stem cells. Annu. Rev. Neurosci. 2009, 32:149-184.
    • (2009) Annu. Rev. Neurosci. , vol.32 , pp. 149-184
    • Kriegstein, A.1    Alvarez-Buylla, A.2
  • 32
    • 34548587064 scopus 로고    scopus 로고
    • FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment
    • Kunath T., Saba-El-Leil M.K., Almousailleakh M., Wray J., Meloche S., Smith A. FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment. Development 2007, 134:2895-2902.
    • (2007) Development , vol.134 , pp. 2895-2902
    • Kunath, T.1    Saba-El-Leil, M.K.2    Almousailleakh, M.3    Wray, J.4    Meloche, S.5    Smith, A.6
  • 36
  • 38
    • 0034797924 scopus 로고    scopus 로고
    • Sequential specification of neurons and glia by developmentally regulated extracellular factors
    • Morrow T., Song M.R., Ghosh A. Sequential specification of neurons and glia by developmentally regulated extracellular factors. Development 2001, 128:3585-3594.
    • (2001) Development , vol.128 , pp. 3585-3594
    • Morrow, T.1    Song, M.R.2    Ghosh, A.3
  • 39
    • 50249103813 scopus 로고    scopus 로고
    • Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development
    • Naka H., Nakamura S., Shimazaki T., Okano H. Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development. Nat. Neurosci. 2008, 11:1014-1023.
    • (2008) Nat. Neurosci. , vol.11 , pp. 1014-1023
    • Naka, H.1    Nakamura, S.2    Shimazaki, T.3    Okano, H.4
  • 42
    • 33748065313 scopus 로고    scopus 로고
    • Induction of oligodendrocyte progenitors in dorsal forebrain by intraventricular microinjection of FGF-2
    • Naruse M., Nakahira E., Miyata T., Hitoshi S., Ikenaka K., Bansal R. Induction of oligodendrocyte progenitors in dorsal forebrain by intraventricular microinjection of FGF-2. Dev. Biol. 2006, 297:262-273.
    • (2006) Dev. Biol. , vol.297 , pp. 262-273
    • Naruse, M.1    Nakahira, E.2    Miyata, T.3    Hitoshi, S.4    Ikenaka, K.5    Bansal, R.6
  • 43
    • 0038771965 scopus 로고    scopus 로고
    • The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling
    • Neel B.G., Gu H., Pao L. The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. Trends Biochem. Sci. 2003, 28:284-293.
    • (2003) Trends Biochem. Sci. , vol.28 , pp. 284-293
    • Neel, B.G.1    Gu, H.2    Pao, L.3
  • 46
    • 27944475835 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein phosphorylation biases cortical precursors to generate neurons rather than astrocytes in vivo
    • Paquin A., Barnabé-Heider F., Kageyama R., Miller F.D. CCAAT/enhancer-binding protein phosphorylation biases cortical precursors to generate neurons rather than astrocytes in vivo. J. Neurosci. 2005, 25:10747-10758.
    • (2005) J. Neurosci. , vol.25 , pp. 10747-10758
    • Paquin, A.1    Barnabé-Heider, F.2    Kageyama, R.3    Miller, F.D.4
  • 47
    • 65649093399 scopus 로고    scopus 로고
    • Costello syndrome H-Ras alleles regulate cortical development
    • Paquin A., Hordo C., Kaplan D.R., Miller F.D. Costello syndrome H-Ras alleles regulate cortical development. Dev. Biol. 2009, 330:440-451.
    • (2009) Dev. Biol. , vol.330 , pp. 440-451
    • Paquin, A.1    Hordo, C.2    Kaplan, D.R.3    Miller, F.D.4
  • 50
    • 84862903108 scopus 로고    scopus 로고
    • Disrupted ERK signaling during cortical development leads to abnormal progenitor proliferation, neuronal and network excitability and behavior, modeling human neuro-cardio-facial-cutaneous and related syndromes
    • Pucilowska J., Puzerey P.A., Karlo J.C., Galán R.F., Landreth G.E. Disrupted ERK signaling during cortical development leads to abnormal progenitor proliferation, neuronal and network excitability and behavior, modeling human neuro-cardio-facial-cutaneous and related syndromes. J. Neurosci. 2012, 32:8663-8677.
    • (2012) J. Neurosci. , vol.32 , pp. 8663-8677
    • Pucilowska, J.1    Puzerey, P.A.2    Karlo, J.C.3    Galán, R.F.4    Landreth, G.E.5
  • 52
    • 78149462716 scopus 로고    scopus 로고
    • Developmental genetics of vertebrate glial-cell specification
    • Rowitch D.H., Kriegstein A.R. Developmental genetics of vertebrate glial-cell specification. Nature 2010, 468:214-222.
    • (2010) Nature , vol.468 , pp. 214-222
    • Rowitch, D.H.1    Kriegstein, A.R.2
  • 53
    • 68349105811 scopus 로고    scopus 로고
    • Fgf10 regulates transition period of cortical stem cell differentiation to radial glia controlling generation of neurons and basal progenitors
    • Sahara S., O'Leary D.D. Fgf10 regulates transition period of cortical stem cell differentiation to radial glia controlling generation of neurons and basal progenitors. Neuron 2009, 63:48-62.
    • (2009) Neuron , vol.63 , pp. 48-62
    • Sahara, S.1    O'Leary, D.D.2
  • 54
  • 55
    • 58549105755 scopus 로고    scopus 로고
    • MAP'ing CNS development and cognition: an ERKsome process
    • Samuels I.S., Saitta S.C., Landreth G.E. MAP'ing CNS development and cognition: an ERKsome process. Neuron 2009, 61:160-167.
    • (2009) Neuron , vol.61 , pp. 160-167
    • Samuels, I.S.1    Saitta, S.C.2    Landreth, G.E.3
  • 56
    • 78751493171 scopus 로고    scopus 로고
    • Deletion of ERK1 and ERK2 in the CNS causes cortical abnormalities and neonatal lethality: Erk1 deficiency enhances the impairment of neurogenesis in Erk2-deficient mice
    • Satoh Y., Kobayashi Y., Takeuchi A., Pagès G., Pouysségur J., Kazama T. Deletion of ERK1 and ERK2 in the CNS causes cortical abnormalities and neonatal lethality: Erk1 deficiency enhances the impairment of neurogenesis in Erk2-deficient mice. J. Neurosci. 2011, 31:1149-1155.
    • (2011) J. Neurosci. , vol.31 , pp. 1149-1155
    • Satoh, Y.1    Kobayashi, Y.2    Takeuchi, A.3    Pagès, G.4    Pouysségur, J.5    Kazama, T.6
  • 57
    • 4344620189 scopus 로고    scopus 로고
    • Mek1 alters epidermal growth and differentiation
    • Scholl F.A., Dumesic P.A., Khavari P.A. Mek1 alters epidermal growth and differentiation. Cancer Res. 2004, 64:6035-6040.
    • (2004) Cancer Res. , vol.64 , pp. 6035-6040
    • Scholl, F.A.1    Dumesic, P.A.2    Khavari, P.A.3
  • 59
    • 0035515347 scopus 로고    scopus 로고
    • The ETS-domain transcription factor family
    • Sharrocks A.D. The ETS-domain transcription factor family. Nat. Rev. Mol. Cell Biol. 2001, 2:827-837.
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 827-837
    • Sharrocks, A.D.1
  • 61
    • 1442299902 scopus 로고    scopus 로고
    • FGF2-induced chromatin remodeling regulates CNTF-mediated gene expression and astrocyte differentiation
    • Song M.R., Ghosh A. FGF2-induced chromatin remodeling regulates CNTF-mediated gene expression and astrocyte differentiation. Nat. Neurosci. 2004, 7:229-235.
    • (2004) Nat. Neurosci. , vol.7 , pp. 229-235
    • Song, M.R.1    Ghosh, A.2
  • 63
    • 15444368299 scopus 로고    scopus 로고
    • Asymmetric distribution of EGFR receptor during mitosis generates diverse CNS progenitor cells
    • Sun Y., Goderie S.K., Temple S. Asymmetric distribution of EGFR receptor during mitosis generates diverse CNS progenitor cells. Neuron 2005, 45:873-886.
    • (2005) Neuron , vol.45 , pp. 873-886
    • Sun, Y.1    Goderie, S.K.2    Temple, S.3
  • 65
    • 68649121646 scopus 로고    scopus 로고
    • The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation
    • Tidyman W.E., Rauen K.A. The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation. Curr. Opin. Genet. Dev. 2009, 19:230-236.
    • (2009) Curr. Opin. Genet. Dev. , vol.19 , pp. 230-236
    • Tidyman, W.E.1    Rauen, K.A.2
  • 67
    • 0038673084 scopus 로고    scopus 로고
    • Epidermal growth factor receptors control competence to interpret leukemia inhibitory factor as an astrocyte inducer in developing cortex
    • Viti J., Feathers A., Phillips J., Lillien L. Epidermal growth factor receptors control competence to interpret leukemia inhibitory factor as an astrocyte inducer in developing cortex. J. Neurosci. 2003, 23:3385-3393.
    • (2003) J. Neurosci. , vol.23 , pp. 3385-3393
    • Viti, J.1    Feathers, A.2    Phillips, J.3    Lillien, L.4
  • 68
    • 69249153394 scopus 로고    scopus 로고
    • A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1
    • Wang J., Whiteman M.W., Lian H., Wang G., Singh A., Huang D., Denmark T. A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1. J. Biol. Chem. 2009, 284:21412-21424.
    • (2009) J. Biol. Chem. , vol.284 , pp. 21412-21424
    • Wang, J.1    Whiteman, M.W.2    Lian, H.3    Wang, G.4    Singh, A.5    Huang, D.6    Denmark, T.7
  • 70
    • 34247517890 scopus 로고    scopus 로고
    • Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo
    • Zhong J., Li X., McNamee C., Chen A.P., Baccarini M., Snider W.D. Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo. Nat. Neurosci. 2007, 10:598-607.
    • (2007) Nat. Neurosci. , vol.10 , pp. 598-607
    • Zhong, J.1    Li, X.2    McNamee, C.3    Chen, A.P.4    Baccarini, M.5    Snider, W.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.