메뉴 건너뛰기




Volumn 19, Issue 21, 1999, Pages 9550-9556

Dopamine D4 receptor-knock-out mice exhibit reduced exploration of novel stimuli

Author keywords

Anxiety; Approach avoidance; D4 receptor; Exploration; Mice; Novelty; Open field

Indexed keywords

DOPAMINE 4 RECEPTOR;

EID: 0033232518     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-21-09550.1999     Document Type: Article
Times cited : (387)

References (40)
  • 1
    • 0022391161 scopus 로고
    • A proposed animal model for hallucinogens based on LSD's effects on patterns of exploration in rats
    • Adams LM, Geyer MA (1985) A proposed animal model for hallucinogens based on LSD's effects on patterns of exploration in rats. Behav Neurosci 99:881-900.
    • (1985) Behav Neurosci , vol.99 , pp. 881-900
    • Adams, L.M.1    Geyer, M.A.2
  • 3
    • 0029120447 scopus 로고
    • Modulation of intracellular cyclic AMP levels by different human dopamine D4 receptor variants
    • Asghari V, Sanyal S, Buchwaldt S, Paterson A, Jovanovic V, Van Tol HH (1995) Modulation of intracellular cyclic AMP levels by different human dopamine D4 receptor variants. J Neurochem 65:1157-1165.
    • (1995) J Neurochem , vol.65 , pp. 1157-1165
    • Asghari, V.1    Sanyal, S.2    Buchwaldt, S.3    Paterson, A.4    Jovanovic, V.5    Van Tol, H.H.6
  • 4
    • 0026437608 scopus 로고
    • Hippocampal mossy fibres: Implication in novelty reactions or in anxiety behaviors?
    • Belzung C (1992) Hippocampal mossy fibres: implication in novelty reactions or in anxiety behaviors? Behav Brain Res 51:149-155.
    • (1992) Behav Brain Res , vol.51 , pp. 149-155
    • Belzung, C.1
  • 5
    • 0027997328 scopus 로고
    • Comparison of different behavioral test situations used in psychopharmacology for measurement of anxiety
    • Belzung C, Le Pape G (1994) Comparison of different behavioral test situations used in psychopharmacology for measurement of anxiety. Physiol Behav 56:623-628.
    • (1994) Physiol Behav , vol.56 , pp. 623-628
    • Belzung, C.1    Le Pape, G.2
  • 6
    • 0030033685 scopus 로고    scopus 로고
    • Population and familial association between the D4 dopamine receptor gene and measures of novelty seeking
    • Benjamin J, Li L, Patterson C, Greenberg BD, Murphy DL, Hamer DH (1996) Population and familial association between the D4 dopamine receptor gene and measures of novelty seeking. Nat Genet 12:81-84.
    • (1996) Nat Genet , vol.12 , pp. 81-84
    • Benjamin, J.1    Li, L.2    Patterson, C.3    Greenberg, B.D.4    Murphy, D.L.5    Hamer, D.H.6
  • 9
    • 0020085273 scopus 로고
    • Topographical distribution of possible glutamatergic pathways from the frontal cortex to the striatum and substantia nigra in rats
    • Carter CJ (1982) Topographical distribution of possible glutamatergic pathways from the frontal cortex to the striatum and substantia nigra in rats. Neuropharmacology 21:379-383.
    • (1982) Neuropharmacology , vol.21 , pp. 379-383
    • Carter, C.J.1
  • 10
    • 0030765116 scopus 로고    scopus 로고
    • Genetic association study between pathological gambling and a functional DNA polymorphism at the D4 receptor gene
    • de Castro PI, Ibanez A, Torres P, Saiz-Ruiz J, Fernandez-Piqueras J (1997) Genetic association study between pathological gambling and a functional DNA polymorphism at the D4 receptor gene. Pharmacogenetics 7:345-348.
    • (1997) Pharmacogenetics , vol.7 , pp. 345-348
    • De Castro, P.I.1    Ibanez, A.2    Torres, P.3    Saiz-Ruiz, J.4    Fernandez-Piqueras, J.5
  • 12
    • 0002007401 scopus 로고
    • Response by the rat to environmental change
    • Dember WN (1956) Response by the rat to environmental change. J Comp Physiol Psychol 49:93-95.
    • (1956) J Comp Physiol Psychol , vol.49 , pp. 93-95
    • Dember, W.N.1
  • 13
    • 0011443563 scopus 로고
    • Visual stimulus complexity and approach behavior in rats
    • Dutch J, Brown LB (1971) Visual stimulus complexity and approach behavior in rats. Psychonom Sci 22:162-63.
    • (1971) Psychonom Sci , vol.22 , pp. 162-163
    • Dutch, J.1    Brown, L.B.2
  • 17
    • 0018759558 scopus 로고
    • Plasma corticosterone concentrations sensitively reflect levels of stimulus intensity in the rat
    • Hennessy MB, Heybach JP, Vernikos J, Levine S (1979) Plasma corticosterone concentrations sensitively reflect levels of stimulus intensity in the rat. Physiol Behav 22:821-825.
    • (1979) Physiol Behav , vol.22 , pp. 821-825
    • Hennessy, M.B.1    Heybach, J.P.2    Vernikos, J.3    Levine, S.4
  • 18
    • 0028235161 scopus 로고
    • Involvement of dopamine and excitatory amino acid transmission in novelty-induced motor activity
    • Hooks MS, Kalivas PW (1994) Involvement of dopamine and excitatory amino acid transmission in novelty-induced motor activity. J Pharmacol Exp Ther 269:976-988.
    • (1994) J Pharmacol Exp Ther , vol.269 , pp. 976-988
    • Hooks, M.S.1    Kalivas, P.W.2
  • 19
    • 0026007133 scopus 로고
    • Response to novelty predicts the locomotor and nucleus accumbens dopamine response to cocaine
    • Hooks MS, Jones GH, Smith AD, Neill DB, Justice JB (1991) Response to novelty predicts the locomotor and nucleus accumbens dopamine response to cocaine. Synapse 9:121-128.
    • (1991) Synapse , vol.9 , pp. 121-128
    • Hooks, M.S.1    Jones, G.H.2    Smith, A.D.3    Neill, D.B.4    Justice, J.B.5
  • 22
    • 0033574375 scopus 로고    scopus 로고
    • Allelic variants of dopamine receptor D4 (D4DR) and serotonin receptor 5HT2c (HTR2c) and temperament factors: Replication tests
    • Kuhn K, Meyer K, Nothen MM, Gansicke M, Papassotiropoulos A, Maier W (1999) Allelic variants of dopamine receptor D4 (D4DR) and serotonin receptor 5HT2c (HTR2c) and temperament factors: replication tests. Am J Med Genet 88:168-172.
    • (1999) Am J Med Genet , vol.88 , pp. 168-172
    • Kuhn, K.1    Meyer, K.2    Nothen, M.M.3    Gansicke, M.4    Papassotiropoulos, A.5    Maier, W.6
  • 24
    • 0031021701 scopus 로고    scopus 로고
    • Epinephrine and norepinephrine act as potent agonists at the recombinant human dopamine D4 receptor
    • Lanau F, Zenner M, Civelli O, Hartman D (1997) Epinephrine and norepinephrine act as potent agonists at the recombinant human dopamine D4 receptor. J Neurochem 68:804-812.
    • (1997) J Neurochem , vol.68 , pp. 804-812
    • Lanau, F.1    Zenner, M.2    Civelli, O.3    Hartman, D.4
  • 25
    • 0030275937 scopus 로고    scopus 로고
    • The association between the dopamine D4 receptor (D4DR) 16 amino acid repeat polymorphism and novelty seeking
    • Malhotra AK, Virkkunen M, Rooney W, Eggert M, Linnoila M, Goldman D (1996) The association between the dopamine D4 receptor (D4DR) 16 amino acid repeat polymorphism and novelty seeking. Mol Psychiatry 1:388-391.
    • (1996) Mol Psychiatry , vol.1 , pp. 388-391
    • Malhotra, A.K.1    Virkkunen, M.2    Rooney, W.3    Eggert, M.4    Linnoila, M.5    Goldman, D.6
  • 26
    • 0001984502 scopus 로고
    • Does neophobia necessarily imply fear or anxiety?
    • Misslin R, Cigrand M (1986) Does neophobia necessarily imply fear or anxiety? Behav Proc 12:45-50.
    • (1986) Behav Proc , vol.12 , pp. 45-50
    • Misslin, R.1    Cigrand, M.2
  • 27
    • 58149446368 scopus 로고
    • The relation between fear induced by novel stimulation and exploratory behavior
    • Montgomery KC (1955) The relation between fear induced by novel stimulation and exploratory behavior. J Comp Physiol Psychol 48:254-260.
    • (1955) J Comp Physiol Psychol , vol.48 , pp. 254-260
    • Montgomery, K.C.1
  • 28
    • 0030805736 scopus 로고    scopus 로고
    • Behavioral performance in three substrains of mouse strain 129
    • Montkowski A, Poettig M, Mederer A, Holsboer F (1997) Behavioral performance in three substrains of mouse strain 129. Brain Res 762:12-18.
    • (1997) Brain Res , vol.762 , pp. 12-18
    • Montkowski, A.1    Poettig, M.2    Mederer, A.3    Holsboer, F.4
  • 29
  • 32
    • 0026599350 scopus 로고
    • Electrophysiological evidence that intrastriatally administered N-methyl-D-aspartate augments striatal dopamine tone in the rat
    • Overton P, Clark D (1992) Electrophysiological evidence that intrastriatally administered N-methyl-D-aspartate augments striatal dopamine tone in the rat. J Neural Transm 4:1-14.
    • (1992) J Neural Transm , vol.4 , pp. 1-14
    • Overton, P.1    Clark, D.2
  • 33
    • 0024470655 scopus 로고
    • Factors that predict individual vulnerability to amphetamine self-administration
    • Piazza PV, Deminiere JM, le Moal M, Simon H (1989) Factors that predict individual vulnerability to amphetamine self-administration. Science 29:1511-1513.
    • (1989) Science , vol.29 , pp. 1511-1513
    • Piazza, P.V.1    Deminiere, J.M.2    Le Moal, M.3    Simon, H.4
  • 34
    • 0026608907 scopus 로고
    • Scopolamine suppresses both locomotion and object contact in a free-exploration situation
    • Renner MJ, Dodson DL, Leduc PA (1992) Scopolamine suppresses both locomotion and object contact in a free-exploration situation. Pharmacol Biochem Behav 41:625-636.
    • (1992) Pharmacol Biochem Behav , vol.41 , pp. 625-636
    • Renner, M.J.1    Dodson, D.L.2    Leduc, P.A.3
  • 37
    • 0031225620 scopus 로고    scopus 로고
    • No association between novelty-seeking and dopamine D4 receptor (D4DR) exon III seven repeat alleles in Baltimore longitudinal study of aging participants
    • Vandenbergh DJ, Zonderman AB, Wang J, Uhl GR, Costa PT (1997) No association between novelty-seeking and dopamine D4 receptor (D4DR) exon III seven repeat alleles in Baltimore Longitudinal Study of Aging participants. Mol Psychiatry 2:417-419.
    • (1997) Mol Psychiatry , vol.2 , pp. 417-419
    • Vandenbergh, D.J.1    Zonderman, A.B.2    Wang, J.3    Uhl, G.R.4    Costa, P.T.5
  • 39
    • 0002259395 scopus 로고
    • "Free" versus "forced" exploration of a novel situation by rats
    • Welker WI (1957) "Free" versus "forced" exploration of a novel situation by rats. Psychol Rep 3:95-108.
    • (1957) Psychol Rep , vol.3 , pp. 95-108
    • Welker, W.I.1
  • 40
    • 0026589657 scopus 로고
    • The release of dopamine from nerve terminals and dendrites of nigrostriatal neurons induced by excitatory amino acids in the conscious rat
    • Westerink BHC, Santiago M, De Vries JB (1992) The release of dopamine from nerve terminals and dendrites of nigrostriatal neurons induced by excitatory amino acids in the conscious rat. Naunyn Schmiedebergs Arch Pharmacol 345:523-529.
    • (1992) Naunyn Schmiedebergs Arch Pharmacol , vol.345 , pp. 523-529
    • Westerink, B.H.C.1    Santiago, M.2    De Vries, J.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.