An evolutionary conserved region in the second intron of the human nestin gene directs gene expression to CNS progenitor cells and to early neural crest cells

European Journal of Neuroscience

Volumn 9, Issue 3, 1997, Pages 452-462

  Lothian, Carina ^a   Lendahl, Urban ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Intermediate filament; Neural tube; Neuroepithelium; Reporter gene; Transgenic mice

Indexed keywords

INTERMEDIATE FILAMENT PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CENTRAL NERVOUS SYSTEM; GENE EXPRESSION; GENE SEQUENCE; INTRON; MOLECULAR CLONING; MOUSE; NEURAL CREST CELL; NEURAL TUBE; NEUROECTODERM; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; SEQUENCE ANALYSIS; STEM CELL; TRANSGENIC MOUSE;

ANIMALS; BASE SEQUENCE; CENTRAL NERVOUS SYSTEM; GENE EXPRESSION; HUMANS; INTERMEDIATE FILAMENT PROTEINS; INTRONS; MICE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEURONS; RATS; STEM CELLS;

EID: 0030980110     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1997.tb01622.x     Document Type: Article

References (4)

1. Bronner-Fraser, M. (1995) Origins and developmental potential of the neural crest. Exp. Cell Res., 218, 405-417.
2. Calof, A. L. (1995) Intrinsic and extrinsic factors regulating vertebrate neurogenesis. Curr. Opin. Neurobiol., 5, 19-27.
3. Dahlstrand, J., Zimmerman, L. B., McKay, R. D. G. and Lendahl, U. (1992) Characterization of the human nestin gene reveals a close evolutionary relationship to neurofilaments. J. Cell Sci., 103, 589-597.
4. Dahlstrand, J., Lardelli, M. and Lendahl, U. (1995) Nestin mRNA expression correlates with the CNS progenitor cell state in many, but not all, regions of developing CNS. Dev. Brain Res., 84, 109-129.