메뉴 건너뛰기




Volumn 88, Issue 12, 2014, Pages 6672-6689

HIV-1 tat protein induces PD-l1 (B7-H1) expression on dendritic cells through tumor necrosis factor alpha- and toll-like receptor 4-mediated mechanisms

Author keywords

[No Author keywords available]

Indexed keywords

PROGRAMMED DEATH 1 LIGAND 1; TOLL LIKE RECEPTOR 4; TRANSACTIVATOR PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84901362621     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00825-14     Document Type: Article
Times cited : (47)

References (80)
  • 1
    • 84867654572 scopus 로고    scopus 로고
    • Innate immune sensing of HIV-1 by dendritic cells
    • Luban J. 2012. Innate immune sensing of HIV-1 by dendritic cells. Cell Host Microbe 12:408-418. http://dx.doi.org/10.1016/j.chom.2012.10.002.
    • (2012) Cell Host Microbe , vol.12 , pp. 408-418
    • Luban, J.1
  • 3
    • 77951094286 scopus 로고    scopus 로고
    • A look behind closed doors: interaction of persistent viruses with dendritic cells
    • Lambotin M, Raghuraman S, Stoll-Keller F, Baumert TF, Barth H.2010. A look behind closed doors: interaction of persistent viruses with dendritic cells. Nat. Rev. Microbiol. 8:350-360. http://dx.doi.org/10.1038/nrmicro2332.
    • (2010) Nat. Rev. Microbiol. , vol.8 , pp. 350-360
    • Lambotin, M.1    Raghuraman, S.2    Stoll-Keller, F.3    Baumert, T.F.4    Barth, H.5
  • 4
    • 59649123419 scopus 로고    scopus 로고
    • Modulation of dendritic cell function by persistent viruses
    • Liu B, Woltman AM, Janssen HL, Boonstra A. 2009. Modulation of dendritic cell function by persistent viruses. J. Leukoc. Biol. 85:205-214. http://dx.doi.org/10.1189/jlb.0408241.
    • (2009) J. Leukoc. Biol. , vol.85 , pp. 205-214
    • Liu, B.1    Woltman, A.M.2    Janssen, H.L.3    Boonstra, A.4
  • 5
    • 33745712871 scopus 로고    scopus 로고
    • Dendritic cells in a mature age
    • Reise Sousa C. 2006. Dendritic cells in a mature age. Nat. Rev. Immunol. 6:476-483. http://dx.doi.org/10.1038/nri1845.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 476-483
    • Reise Sousa, C.1
  • 6
    • 84879285507 scopus 로고    scopus 로고
    • Dendritic cell dysregulation during HIV-1 infection
    • Miller E, Bhardwaj N. 2013. Dendritic cell dysregulation during HIV-1 infection. Immunol. Rev. 254:170-189. http://dx.doi.org/10.1111/imr.12082.
    • (2013) Immunol. Rev. , vol.254 , pp. 170-189
    • Miller, E.1    Bhardwaj, N.2
  • 8
    • 38549149823 scopus 로고    scopus 로고
    • Immune activation and inflammation in HIV-1 infection: causes and consequences
    • Appay V, Sauce D. 2008. Immune activation and inflammation in HIV-1 infection: causes and consequences. J. Pathol. 214:231-241. http://dx.doi.org/10.1002/path.2276.
    • (2008) J. Pathol. , vol.214 , pp. 231-241
    • Appay, V.1    Sauce, D.2
  • 9
    • 84871648235 scopus 로고    scopus 로고
    • The paradox of the immune response in HIV infection: when inflammation becomes harmful
    • Ipp H, Zemlin A. 2013. The paradox of the immune response in HIV infection: when inflammation becomes harmful. Clin. Chim. Acta 416: 96-99. http://dx.doi.org/10.1016/j.cca.2012.11.025.
    • (2013) Clin. Chim. Acta , vol.416 , pp. 96-99
    • Ipp, H.1    Zemlin, A.2
  • 10
    • 79952705605 scopus 로고    scopus 로고
    • Revisiting immune exhaustion during HIV infection
    • Khaitan A, Unutmaz D. 2011. Revisiting immune exhaustion during HIV infection. Curr. HIV/AIDS Rep. 8:4-11. http://dx.doi.org/10.1007/s11904-010-0066-0.
    • (2011) Curr. HIV/AIDS Rep. , vol.8 , pp. 4-11
    • Khaitan, A.1    Unutmaz, D.2
  • 11
    • 84873446224 scopus 로고    scopus 로고
    • Monitoring cellular immune markers in HIV infection: from activation to exhaustion
    • Sauce D, Elbim C, Appay V. 2013. Monitoring cellular immune markers in HIV infection: from activation to exhaustion. Curr. Opin. HIV AIDS 8:125-131. http://dx.doi.org/10.1097/COH.0b013e32835d08a9.
    • (2013) Curr. Opin. HIV AIDS , vol.8 , pp. 125-131
    • Sauce, D.1    Elbim, C.2    Appay, V.3
  • 12
    • 34247170486 scopus 로고    scopus 로고
    • HIV-1 immunopathogenesis: how good interferon turns bad
    • Herbeuval JP, Shearer GM. 2007. HIV-1 immunopathogenesis: how good interferon turns bad. Clin. Immunol. 123:121-128. http://dx.doi.org/10.1016/j.clim.2006.09.016.
    • (2007) Clin. Immunol. , vol.123 , pp. 121-128
    • Herbeuval, J.P.1    Shearer, G.M.2
  • 13
    • 84862908654 scopus 로고    scopus 로고
    • Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo
    • Swiecki M, Wang Y, Vermi W, Gilfillan S, Schreiber RD, Colonna M. 2011. Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo. J. Exp. Med. 208:2367-2374. http://dx.doi.org/10.1084/jem.20110654.
    • (2011) J. Exp. Med. , vol.208 , pp. 2367-2374
    • Swiecki, M.1    Wang, Y.2    Vermi, W.3    Gilfillan, S.4    Schreiber, R.D.5    Colonna, M.6
  • 14
    • 78651238652 scopus 로고    scopus 로고
    • Early myeloid dendritic cell dysregulation is predictive of disease progression in simian immunodeficiency virus infection
    • Wijewardana V, SoloffAC, Liu X, Brown KN, Barratt-Boyes SM. 2010. Early myeloid dendritic cell dysregulation is predictive of disease progression in simian immunodeficiency virus infection. PLoS Pathog. 6:e1001235. http://dx.doi.org/10.1371/journal.ppat.1001235.
    • (2010) PLoS Pathog. , vol.6
    • Wijewardana, V.1    Soloff, A.C.2    Liu, X.3    Brown, K.N.4    Barratt-Boyes, S.M.5
  • 15
    • 80052338862 scopus 로고    scopus 로고
    • The cytokine network of acute HIV infection: a promising target for vaccines and therapy to reduce viral set-point?
    • Katsikis PD, Mueller YM, Villinger F. 2011. The cytokine network of acute HIV infection: a promising target for vaccines and therapy to reduce viral set-point? PLoS Pathog. 7:e1002055. http://dx.doi.org/10.1371/journal.ppat.1002055.
    • (2011) PLoS Pathog , vol.7
    • Katsikis, P.D.1    Mueller, Y.M.2    Villinger, F.3
  • 16
    • 84864910464 scopus 로고    scopus 로고
    • Soluble mediators of inflammation in HIV and their implications for therapeutics and vaccine development
    • Keating SM, Jacobs ES, Norris PJ. 2012. Soluble mediators of inflammation in HIV and their implications for therapeutics and vaccine development. Cytokine Growth Factor Rev. 23:193-206. http://dx.doi.org/10.1016/j.cytogfr.2012.05.006.
    • (2012) Cytokine Growth Factor Rev. , vol.23 , pp. 193-206
    • Keating, S.M.1    Jacobs, E.S.2    Norris, P.J.3
  • 17
    • 48749119366 scopus 로고    scopus 로고
    • Structures of PD-1 with its ligands: sideways and dancing cheek to cheek
    • Freeman GJ. 2008. Structures of PD-1 with its ligands: sideways and dancing cheek to cheek. Proc. Natl. Acad. Sci. U. S. A. 105:10275-10276. http://dx.doi.org/10.1073/pnas.0805459105.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 10275-10276
    • Freeman, G.J.1
  • 18
    • 33749324118 scopus 로고    scopus 로고
    • Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade
    • Freeman GJ, Wherry EJ, Ahmed R, Sharpe AH. 2006. Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade. J. Exp. Med. 203:2223-2227. http://dx.doi.org/10.1084/jem.20061800.
    • (2006) J. Exp. Med. , vol.203 , pp. 2223-2227
    • Freeman, G.J.1    Wherry, E.J.2    Ahmed, R.3    Sharpe, A.H.4
  • 20
    • 78650644622 scopus 로고    scopus 로고
    • Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression
    • Xu H, Wang X, Pahar B, Moroney-Rasmussen T, Alvarez X, Lackner AA, Veazey RS. 2010. Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression. J. Immunol. 185:7340-7348. http://dx.doi.org/10.4049/jimmunol.1001642.
    • (2010) J. Immunol. , vol.185 , pp. 7340-7348
    • Xu, H.1    Wang, X.2    Pahar, B.3    Moroney-Rasmussen, T.4    Alvarez, X.5    Lackner, A.A.6    Veazey, R.S.7
  • 21
    • 45549092692 scopus 로고    scopus 로고
    • Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques
    • Estes JD, Gordon SN, Zeng M, Chahroudi AM, Dunham RM, Staprans SI, Reilly CS, Silvestri G, Haase AT. 2008. Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques. J. Immunol. 180:6798-6807.
    • (2008) J. Immunol. , vol.180 , pp. 6798-6807
    • Estes, J.D.1    Gordon, S.N.2    Zeng, M.3    Chahroudi, A.M.4    Dunham, R.M.5    Staprans, S.I.6    Reilly, C.S.7    Silvestri, G.8    Haase, A.T.9
  • 22
    • 42649125225 scopus 로고    scopus 로고
    • PD-1 and its ligands in tolerance and immunity
    • Keir ME, Butte MJ, Freeman GJ, Sharpe AH. 2008. PD-1 and its ligands in tolerance and immunity. Annu. Rev. Immunol. 26:677-704. http://dx.doi.org/10.1146/annurev.immunol.26.021607.090331.
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 677-704
    • Keir, M.E.1    Butte, M.J.2    Freeman, G.J.3    Sharpe, A.H.4
  • 23
    • 58149339765 scopus 로고    scopus 로고
    • B7-H1 up-regulation impairs myeloid DC and correlates with disease progression in chronic HIV-1 infection
    • Wang X, Zhang Z, Zhang S, Fu J, Yao J, Jiao Y, Wu H, Wang FS. 2008. B7-H1 up-regulation impairs myeloid DC and correlates with disease progression in chronic HIV-1 infection. Eur. J. Immunol. 38:3226-3236. http://dx.doi.org/10.1002/eji.200838285.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 3226-3236
    • Wang, X.1    Zhang, Z.2    Zhang, S.3    Fu, J.4    Yao, J.5    Jiao, Y.6    Wu, H.7    Wang, F.S.8
  • 25
    • 77954409827 scopus 로고    scopus 로고
    • Increased PD-L1 expression and PD-L1/CD86 ratio on dendritic cells were associated with impaired dendritic cells function in HCV infection
    • Shen T, Chen X, Chen Y, Xu Q, Lu F, Liu S. 2010. Increased PD-L1 expression and PD-L1/CD86 ratio on dendritic cells were associated with impaired dendritic cells function in HCV infection. J. Med. Virol. 82: 1152-1159. http://dx.doi.org/10.1002/jmv.21809.
    • (2010) J. Med. Virol. , vol.82 , pp. 1152-1159
    • Shen, T.1    Chen, X.2    Chen, Y.3    Xu, Q.4    Lu, F.5    Liu, S.6
  • 28
    • 84863734405 scopus 로고    scopus 로고
    • Blocking of PDL-1 interaction enhances primary and secondary CD8 T cell response to herpes simplex virus-1 infection
    • Channappanavar R, Twardy BS, Suvas S. 2012. Blocking of PDL-1 interaction enhances primary and secondary CD8 T cell response to herpes simplex virus-1 infection. PLoS One 7:e39757. http://dx.doi.org/10.1371/journal.pone.0039757.
    • (2012) PLoS One , vol.7
    • Channappanavar, R.1    Twardy, B.S.2    Suvas, S.3
  • 30
    • 84860584561 scopus 로고    scopus 로고
    • PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques
    • Dyavar Shetty R, Velu V, Titanji K, Bosinger SE, Freeman GJ, Silvestri G, Amara RR. 2012. PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques. J. Clin. Invest. 122:1712-1716. http://dx.doi.org/10.1172/JCI60612.
    • (2012) J. Clin. Invest. , vol.122 , pp. 1712-1716
    • Dyavar Shetty, R.1    Velu, V.2    Titanji, K.3    Bosinger, S.E.4    Freeman, G.J.5    Silvestri, G.6    Amara, R.R.7
  • 33
    • 0033766287 scopus 로고    scopus 로고
    • Tat protein of human immunodeficiency virus type 1 induces interleukin- 10 in human peripheral blood monocytes: implication of protein kinase C-dependent pathway
    • Badou A, Bennasser Y, Moreau M, Leclerc C, Benkirane M, Bahraoui E. 2000. Tat protein of human immunodeficiency virus type 1 induces interleukin- 10 in human peripheral blood monocytes: implication of protein kinase C-dependent pathway. J. Virol. 74:10551-10562. http://dx.doi.org/10.1128/JVI.74.22.10551-10562.2000.
    • (2000) J. Virol. , vol.74 , pp. 10551-10562
    • Badou, A.1    Bennasser, Y.2    Moreau, M.3    Leclerc, C.4    Benkirane, M.5    Bahraoui, E.6
  • 34
  • 35
    • 34248592116 scopus 로고    scopus 로고
    • Human immunodeficiency virus type-1 protein Tat induces tumor necrosis factor-alpha-mediated neurotoxicity
    • Buscemi L, Ramonet D, Geiger JD. 2007. Human immunodeficiency virus type-1 protein Tat induces tumor necrosis factor-alpha-mediated neurotoxicity. Neurobiol. Dis. 26:661-670. http://dx.doi.org/10.1016/j.nbd.2007.03.004.
    • (2007) Neurobiol. Dis. , vol.26 , pp. 661-670
    • Buscemi, L.1    Ramonet, D.2    Geiger, J.D.3
  • 36
    • 5644235307 scopus 로고    scopus 로고
    • IL-10 production induced by HIV-1 Tat stimulation of human monocytes is dependent on the activation of PKC beta(II) and delta isozymes
    • Contreras X, Bennasser Y, Bahraoui E. 2004. IL-10 production induced by HIV-1 Tat stimulation of human monocytes is dependent on the activation of PKC beta(II) and delta isozymes. Microbes Infect. 6:1182-1190. http://dx.doi.org/10.1016/j.micinf.2004.06.008.
    • (2004) Microbes Infect. , vol.6 , pp. 1182-1190
    • Contreras, X.1    Bennasser, Y.2    Bahraoui, E.3
  • 37
    • 0036136322 scopus 로고    scopus 로고
    • Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigenspecific T cell responses
    • Fanales-Belasio E, Moretti S, Nappi F, Barillari G, Micheletti F, Cafaro A, Ensoli B. 2002. Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigenspecific T cell responses. J. Immunol. 168:197-206.
    • (2002) J. Immunol. , vol.168 , pp. 197-206
    • Fanales-Belasio, E.1    Moretti, S.2    Nappi, F.3    Barillari, G.4    Micheletti, F.5    Cafaro, A.6    Ensoli, B.7
  • 38
    • 70349221406 scopus 로고    scopus 로고
    • Differential effects of HIV type 1 clade B and clade C Tat protein on expression of proinflammatory and antiinflammatory cytokines by primary monocytes
    • Gandhi N, Saiyed Z, Thangavel S, Rodriguez J, Rao KV, Nair MP. 2009. Differential effects of HIV type 1 clade B and clade C Tat protein on expression of proinflammatory and antiinflammatory cytokines by primary monocytes. AIDS Res. Hum. Retroviruses 25:691-699. http://dx.doi.org/10.1089/aid.2008.0299.
    • (2009) AIDS Res. Hum. Retroviruses , vol.25 , pp. 691-699
    • Gandhi, N.1    Saiyed, Z.2    Thangavel, S.3    Rodriguez, J.4    Rao, K.V.5    Nair, M.P.6
  • 39
    • 33845978054 scopus 로고    scopus 로고
    • Intracellular HIV-Tat expression induces IL-10 synthesis by the CREB-1 transcription factor through Ser133 phosphorylation and its regulation by the ERK1/2 MAPK in human monocytic cells
    • Gee K, Angel JB, Ma W, Mishra S, Gajanayaka N, Parato K, Kumar A. 2006. Intracellular HIV-Tat expression induces IL-10 synthesis by the CREB-1 transcription factor through Ser133 phosphorylation and its regulation by the ERK1/2 MAPK in human monocytic cells. J. Biol. Chem. 281:31647-31658. http://dx.doi.org/10.1074/jbc. M512109200.
    • (2006) J. Biol. Chem. , vol.281 , pp. 31647-31658
    • Gee, K.1    Angel, J.B.2    Ma, W.3    Mishra, S.4    Gajanayaka, N.5    Parato, K.6    Kumar, A.7
  • 40
    • 40449085163 scopus 로고    scopus 로고
    • HIV-1 Tat suppresses gp120-specific T cell response in IL-10-dependent manner
    • Gupta S, Boppana R, Mishra GC, Saha B, Mitra D. 2008. HIV-1 Tat suppresses gp120-specific T cell response in IL-10-dependent manner. J. Immunol. 180:79-88.
    • (2008) J. Immunol. , vol.180 , pp. 79-88
    • Gupta, S.1    Boppana, R.2    Mishra, G.C.3    Saha, B.4    Mitra, D.5
  • 42
    • 51449117370 scopus 로고    scopus 로고
    • HIV-1 Tat protein induces IL-10 production by an alternative TNF-alpha-independent pathway in monocytes: role of PKC-delta and p38 MAP kinase
    • Leghmari K, Bennasser Y, Tkaczuk J, Bahraoui E. 2008. HIV-1 Tat protein induces IL-10 production by an alternative TNF-alpha-independent pathway in monocytes: role of PKC-delta and p38 MAP kinase. Cell Immunol. 253:45-53. http://dx.doi.org/10.1016/j.cellimm.2008.04.015.
    • (2008) Cell Immunol. , vol.253 , pp. 45-53
    • Leghmari, K.1    Bennasser, Y.2    Tkaczuk, J.3    Bahraoui, E.4
  • 43
    • 0031766431 scopus 로고    scopus 로고
    • HIV-I Tat: a polypeptide for all seasons
    • Rubartelli A, Poggi A, Sitia R, Zocchi MR. 1998. HIV-I Tat: a polypeptide for all seasons. Immunol. Today 19:543-545. http://dx.doi.org/10.1016/S0167-5699(98)01351-6.
    • (1998) Immunol. Today , vol.19 , pp. 543-545
    • Rubartelli, A.1    Poggi, A.2    Sitia, R.3    Zocchi, M.R.4
  • 44
    • 0029840636 scopus 로고    scopus 로고
    • HIV-1 Tat protein as a potential AIDS vaccine
    • Goldstein G. 1996. HIV-1 Tat protein as a potential AIDS vaccine. Nat. Med. 2:960-964. http://dx.doi.org/10.1038/nm0996-960.
    • (1996) Nat. Med. , vol.2 , pp. 960-964
    • Goldstein, G.1
  • 47
    • 0035793619 scopus 로고    scopus 로고
    • Internalization of HIV-1 Tat requires cell surface heparan sulfate proteoglycans
    • Tyagi M, Rusnati M, Presta M, Giacca M. 2001. Internalization of HIV-1 Tat requires cell surface heparan sulfate proteoglycans. J. Biol. Chem. 276:3254-3261. http://dx.doi.org/10.1074/jbc. M006701200.
    • (2001) J. Biol. Chem. , vol.276 , pp. 3254-3261
    • Tyagi, M.1    Rusnati, M.2    Presta, M.3    Giacca, M.4
  • 48
    • 0034566395 scopus 로고    scopus 로고
    • From the outside in: extracellular activities of HIV Tat
    • Noonan D, Albini A. 2000. From the outside in: extracellular activities of HIV Tat. Adv. Pharmacol. 48:229-250. http://dx.doi.org/10.1016/S1054-3589(00)48008-7.
    • (2000) Adv. Pharmacol. , vol.48 , pp. 229-250
    • Noonan, D.1    Albini, A.2
  • 49
    • 0027458469 scopus 로고
    • Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation
    • Ensoli B, Buonaguro L, Barillari G, Fiorelli V, Gendelman R, Morgan RA, Wingfield P, Gallo RC. 1993. Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation. J. Virol. 67:277-287.
    • (1993) J. Virol. , vol.67 , pp. 277-287
    • Ensoli, B.1    Buonaguro, L.2    Barillari, G.3    Fiorelli, V.4    Gendelman, R.5    Morgan, R.A.6    Wingfield, P.7    Gallo, R.C.8
  • 50
    • 76249086418 scopus 로고    scopus 로고
    • HIV-1 clade B Tat, but not cladeCTat, increases X4 HIV-1 entry into resting but not activated CD4+ T cells
    • Campbell GR, Loret EP, Spector SA. 2010. HIV-1 clade B Tat, but not cladeCTat, increases X4 HIV-1 entry into resting but not activated CD4α T cells. J. Biol. Chem. 285:1681-1691. http://dx.doi.org/10.1074/jbc. M109.049957.
    • (2010) J. Biol. Chem. , vol.285 , pp. 1681-1691
    • Campbell, G.R.1    Loret, E.P.2    Spector, S.A.3
  • 51
    • 22844450207 scopus 로고    scopus 로고
    • Extracellular HIV Tat and Tat cysteine rich peptide increase CCR5 expression in monocytes
    • Zheng L, Yang YD, Lu GC, Salvato MS. 2005. Extracellular HIV Tat and Tat cysteine rich peptide increase CCR5 expression in monocytes. J. Zhejiang Univ. Sci. B 6:668-672. http://dx.doi.org/10.1631/jzus.2005.B0668.
    • (2005) J. Zhejiang Univ. Sci. B , vol.6 , pp. 668-672
    • Zheng, L.1    Yang, Y.D.2    Lu, G.C.3    Salvato, M.S.4
  • 54
    • 0030068995 scopus 로고    scopus 로고
    • Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic
    • Nath A, Psooy K, Martin C, Knudsen B, Magnuson DS, Haughey N, Geiger JD. 1996. Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic. J. Virol. 70:1475-1480.
    • (1996) J. Virol. , vol.70 , pp. 1475-1480
    • Nath, A.1    Psooy, K.2    Martin, C.3    Knudsen, B.4    Magnuson, D.S.5    Haughey, N.6    Geiger, J.D.7
  • 57
    • 0029062573 scopus 로고
    • Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein
    • Li CJ, Friedman DJ, Wang C, Metelev V, Pardee AB. 1995. Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein. Science 268: 429-431. http://dx.doi.org/10.1126/science.7716549.
    • (1995) Science , vol.268 , pp. 429-431
    • Li, C.J.1    Friedman, D.J.2    Wang, C.3    Metelev, V.4    Pardee, A.B.5
  • 58
    • 0028223435 scopus 로고
    • Human immunodeficiency virus 1 Tat binds to dipeptidyl aminopeptidase IV (CD26): a possible mechanism for Tat's immunosuppressive activity
    • Gutheil WG, Subramanyam M, Flentke GR, Sanford DG, Munoz E, Huber BT, Bachovchin WW. 1994. Human immunodeficiency virus 1 Tat binds to dipeptidyl aminopeptidase IV (CD26): a possible mechanism for Tat's immunosuppressive activity. Proc. Natl. Acad. Sci. U. S. A. 91: 6594-6598. http://dx.doi.org/10.1073/pnas.91.14.6594.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 6594-6598
    • Gutheil, W.G.1    Subramanyam, M.2    Flentke, G.R.3    Sanford, D.G.4    Munoz, E.5    Huber, B.T.6    Bachovchin, W.W.7
  • 59
    • 12344307860 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Tat protein induces an intracellular calcium increase in human monocytes that requires DHP receptors: involvement in TNF-alpha production
    • Contreras X, Bennasser Y, Chazal N, Moreau M, Leclerc C, Tkaczuk J, Bahraoui E. 2005. Human immunodeficiency virus type 1 Tat protein induces an intracellular calcium increase in human monocytes that requires DHP receptors: involvement in TNF-alpha production. Virology 332:316-328. http://dx.doi.org/10.1016/j.virol.2004.11.032.
    • (2005) Virology , vol.332 , pp. 316-328
    • Contreras, X.1    Bennasser, Y.2    Chazal, N.3    Moreau, M.4    Leclerc, C.5    Tkaczuk, J.6    Bahraoui, E.7
  • 60
    • 0030791368 scopus 로고    scopus 로고
    • The RGD-containing domain of exogenous HIV-1 Tat inhibits the engulfment of apoptotic bodies by dendritic cells
    • Zocchi MR, Poggi A, Rubartelli A. 1997. The RGD-containing domain of exogenous HIV-1 Tat inhibits the engulfment of apoptotic bodies by dendritic cells. AIDS 11:1227-1235. http://dx.doi.org/10.1097/00002030-199710000-00005.
    • (1997) AIDS , vol.11 , pp. 1227-1235
    • Zocchi, M.R.1    Poggi, A.2    Rubartelli, A.3
  • 62
    • 84890115621 scopus 로고    scopus 로고
    • HIV-1 Tat protein binds to TLR4-MD2 and signals to induce TNF-alpha and IL-10
    • Haij NB, Leghmari K, Planes R, Thieblemont N, Bahraoui E. 2013. HIV-1 Tat protein binds to TLR4-MD2 and signals to induce TNF-alpha and IL-10. Retrovirology 10:123. http://dx.doi.org/10.1186/1742-4690-10-123.
    • (2013) Retrovirology , vol.10 , pp. 123
    • Haij, N.B.1    Leghmari, K.2    Planes, R.3    Thieblemont, N.4    Bahraoui, E.5
  • 63
    • 0028355464 scopus 로고
    • Effects of the Tat basic domain on human immunodeficiency virus type 1 transactivation, using chemically synthesized Tat protein and Tat peptides
    • Vives E, Charneau P, van Rietschoten J, Rochat H, Bahraoui E. 1994. Effects of the Tat basic domain on human immunodeficiency virus type 1 transactivation, using chemically synthesized Tat protein and Tat peptides. J. Virol. 68:3343-3353.
    • (1994) J. Virol. , vol.68 , pp. 3343-3353
    • Vives, E.1    Charneau, P.2    van Rietschoten, J.3    Rochat, H.4    Bahraoui, E.5
  • 67
    • 0036930057 scopus 로고    scopus 로고
    • Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha
    • Bennasser Y, Badou A, Tkaczuk J, Bahraoui E. 2002. Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha. Virology 303:174-180. http://dx.doi.org/10.1006/viro.2002.1676.
    • (2002) Virology , vol.303 , pp. 174-180
    • Bennasser, Y.1    Badou, A.2    Tkaczuk, J.3    Bahraoui, E.4
  • 68
    • 54149086493 scopus 로고    scopus 로고
    • HIV-1 Tat protein induces IL-10 production in monocytes by classical and alternative NF-kappaB pathways
    • Leghmari K, Bennasser Y, Bahraoui E. 2008. HIV-1 Tat protein induces IL-10 production in monocytes by classical and alternative NF-kappaB pathways. Eur. J. Cell Biol. 87:947-962. http://dx.doi.org/10.1016/j.ejcb.2008.06.005.
    • (2008) Eur. J. Cell Biol. , vol.87 , pp. 947-962
    • Leghmari, K.1    Bennasser, Y.2    Bahraoui, E.3
  • 69
    • 77955141524 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 clade B and C Tat differentially induce indoleamine 2,3-dioxygenase and serotonin in immature dendritic cells: implications for neuroAIDS
    • Samikkannu T, Rao KV, Gandhi N, Saxena SK, Nair MP. 2010. Human immunodeficiency virus type 1 clade B and C Tat differentially induce indoleamine 2,3-dioxygenase and serotonin in immature dendritic cells: implications for neuroAIDS. J. Neurovirol. 16:255-263. http://dx.doi.org/10.3109/13550284.2010.497809.
    • (2010) J. Neurovirol. , vol.16 , pp. 255-263
    • Samikkannu, T.1    Rao, K.V.2    Gandhi, N.3    Saxena, S.K.4    Nair, M.P.5
  • 72
    • 34347394736 scopus 로고    scopus 로고
    • Modulation of dendritic cell maturation and function by the Tax protein of human T cell leukemia virus type 1
    • Jain P, Ahuja J, Khan ZK, Shimizu S, Meucci O, Jennings SR, Wigdahl B. 2007. Modulation of dendritic cell maturation and function by the Tax protein of human T cell leukemia virus type 1. J. Leukoc. Biol. 82:44-56. http://dx.doi.org/10.1189/jlb.1006641.
    • (2007) J. Leukoc. Biol. , vol.82 , pp. 44-56
    • Jain, P.1    Ahuja, J.2    Khan, Z.K.3    Shimizu, S.4    Meucci, O.5    Jennings, S.R.6    Wigdahl, B.7
  • 73
    • 20744435124 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Vpr impairs dendritic cell maturation and T-cell activation: implications for viral immune escape
    • Majumder B, Janket ML, Schafer EA, Schaubert K, Huang XL, Kan-Mitchell J, Rinaldo CR, Jr, Ayyavoo V. 2005. Human immunodeficiency virus type 1 Vpr impairs dendritic cell maturation and T-cell activation: implications for viral immune escape. J. Virol. 79:7990-8003. http://dx.doi.org/10.1128/JVI.79.13.7990-8003.2005.
    • (2005) J. Virol. , vol.79 , pp. 7990-8003
    • Majumder, B.1    Janket, M.L.2    Schafer, E.A.3    Schaubert, K.4    Huang, X.L.5    Kan-Mitchell, J.6    Rinaldo, C.R.7    Ayyavoo, V.8
  • 74
    • 0037330043 scopus 로고    scopus 로고
    • HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages
    • Izmailova E, Bertley FM, Huang Q, Makori N, Miller CJ, Young RA, Aldovini A. 2003. HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages. Nat. Med. 9:191-197. http://dx.doi.org/10.1038/nm822.
    • (2003) Nat. Med. , vol.9 , pp. 191-197
    • Izmailova, E.1    Bertley, F.M.2    Huang, Q.3    Makori, N.4    Miller, C.J.5    Young, R.A.6    Aldovini, A.7
  • 75
    • 78650644622 scopus 로고    scopus 로고
    • Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression
    • Xu H, Wang X, Pahar B, Moroney-Rasmussen T, Alvarez X, Lackner AA, Veazey RS. 2010. Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression. J. Immunol. 185:7340-7348. http://dx.doi.org/10.4049/jimmunol.1001642.
    • (2010) J. Immunol. , vol.185 , pp. 7340-7348
    • Xu, H.1    Wang, X.2    Pahar, B.3    Moroney-Rasmussen, T.4    Alvarez, X.5    Lackner, A.A.6    Veazey, R.S.7
  • 77
    • 79952825942 scopus 로고    scopus 로고
    • Expression of a broad array of negative costimulatory molecules and Blimp-1 in T-cells following priming by HIV-1 pulsed dendritic cells
    • Shankar EM, Che KF, Messmer D, Lifson JD, Larsson M. 2011. Expression of a broad array of negative costimulatory molecules and Blimp-1 in T-cells following priming by HIV-1 pulsed dendritic cells. Mol. Med. 17: 229-240. http://dx.doi.org/10.2119/molmed.2010.00175.
    • (2011) Mol. Med. , vol.17 , pp. 229-240
    • Shankar, E.M.1    Che, K.F.2    Messmer, D.3    Lifson, J.D.4    Larsson, M.5
  • 78
    • 84884491148 scopus 로고    scopus 로고
    • HIV-1 Tat protein induces the production of IDO in human monocyte derived-dendritic cells through a direct mechanism: effect on T cells proliferation
    • Planes R, Bahraoui E. 2013. HIV-1 Tat protein induces the production of IDO in human monocyte derived-dendritic cells through a direct mechanism: effect on T cells proliferation. PLoS One 8:e74551. http://dx.doi.org/10.1371/journal.pone.0074551.
    • (2013) PLoS One , vol.8
    • Planes, R.1    Bahraoui, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.