Signaling pathways triggered by HIV-1 tat in human monocytes to induce TNF-α

Virology

Volumn 303, Issue 1, 2002, Pages 174-180

  Bennasser, Yamina ^a   Badou, Abdallah ^a   Tkaczuk, Jean ^a   Bahraoui, Elmostafa ^a  

^a UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

HIV Tat; Human monocyte; Signalization; TNF

Indexed keywords

CALCIUM; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROTEIN KINASE C; TRANSACTIVATOR PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; DOWNSTREAM PROCESSING; ENZYME SYNTHESIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0036930057     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.2002.1676     Document Type: Article

References (22)

1. Albini, A., Soldi, R., Giunciuglio, D., Giraudo, E., Benelli, R., Primo, L., Noonan, D., Salio, M., Camussi, G., Rockl, W., and Bussolino, F. (1996). The angiogenesis induced by HIV-1 tat protein is mediated by the Flk-1/KDR receptor on vascular endothelial cells. Nat. Med. 2, 1371.
2. Baeuerle, P. A., and Baltimore, D. (1996). NF-kB: Ten years after. Cell 87, 13-20.
3. Bennasser, Y., and Bahraoui, E. (2002). HIV-1 Tat protein induces interleukin-10 in human peripheral blood monocytes: Involvement of protein kinase C-betaII and -delta. FASEB J. 16(6), 546-554.
4. Briant, L., Robert-Hebmann, V., Acquaviva, C., Pelchen-Matthews, A., Marsh, M., and Devaux, C. (1998). The protein tyrosine kinase p56lck is required for triggering NF-kB activation upon interaction of human immunodeficiency virus type 1 envelope glycoprotein gp120 with cell surface CD4. J. Virol. 72, 6207.
5. Chen, P., Mayne, M., Power, C., and Nath, A. (1997). The Tat protein of HIV-1 induces tumor necrosis factor-α production. J. Biol. Chem. 272, 22385-22388.
6. Ensoli, B., Buonaguro, L., Barillari, G., Fiorelli, V., Gendelman, R., Morgan, R. A., Wingfield, P., and Gallo, R. C. (1993). Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation. J. Virol. 67, 277-287.
7. Fauci, A. S. (1988). The human immunodeficiency virus: Infectivity and mechanisms of pathogenesis. Science 239(4840), 617-622.
8. Fauci, A. S. (1996). Host factors and the pathogenesis of HIV-induced disease. Nature 384, 529-534.
9. Fraser, J. D., Straus, D., and Weiss, A. (1993). Signal transduction events leading to T-cell lymphokine gene expression. Immunol. Today 14(7), 357-362.
10. Haughey, N. C., Holden, C. P., Nath, A., and Geiger, J. D. (1999). Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dyregulation and neurone cell death caused by HIV-1 protein Tat. J. Neurobiochem. 73, 1363-1374.
11. Mann, D. A., and Frankel, A. D. (1991). Endocytosis and targeting of exogenous HIV-1 Tat protein. EMBO J. 10, 1733-1739.
12. Mayne, M., Holden, C. P., Nath, A., and Geiger, D. (2000). Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-Tat regulates TNF-3 production in human macrophages. J. Immunol. 164, 6538-6542.
13. Meinkoth, J. L., Alberts, A. S., Went, W., Fantozzi, D., Taylor, S. S., Hagiwara, M., Montminy, M., and Feramisco, J. R. (1993). Signal transduction through the cAMP dependent protein kinase. Mol. Cell. Biochem. 127, 179-186.
14. Rao, A. (1994). NF-ATp: A transcription factor required for the coordinate induction of several cytokine genes. Immunol. Today 15, 274-281.
15. Rosenberg, Z., and Fauci, A. (1990). Immunopathogenic mechanisms of HIV infection: Cytokine induction of HIV expression. Immunol. Today 11 (5), 176-180.
16. Rubartelli, A., Poggi, A., Sitia, R., and Zocchi, M. R. (1998). HIV-1 Tat: A polypeptide for all seasons. Immunol. Today 19, 543-545.
17. Sabatier, J., Vives, E., Mabrouk, K., Benjouad, A., Rochat, H., Duval, A., Hue, B., and Bahraoui, E. (1991). Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1. J. Virol. 65, 961-967.
18. Talley, A. K., Dewhurst, S., Perry, S. W., Dollard, S. C., Gummuluru, S., Fine, S. M., New, D., Gendelman, H. E., and Gelbart, H. A. (1995). Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: Protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA. Mol. Cell. Biol. 15(5), 2359-2366.
19. Ueda, Y., Hirai, S., Osada, S., Suzuki, A., Mizuno, K., and Ohno, S. (1996). Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf. J. Biol. Chem. 271, 23512-23519.
20. Westendorp, M. O., Frank, R., Ochsenbauer, C., Stricker, K., Dhein, J., Waiczak, H., Deabtin, K., M., and Krammer, P., H., (1995). Sensitization of T cell to CD95-mediated apoptosis by HIV-1 Tat and gp120. Nature 375, 497-500.
21. Wright, S. C., Jewett, A., Mitsuyasu, R., and Bonavida, B. (1988). Spontaneous cytotoxicity and tumor necrosis factor production by peripheral blood monocytes from AIDS patients. J. Immunol. 141(1), 99-104.
22. Xiao, H., Neuveut, C., Tiffany, H. L., Benkirane, M., Rich, E. A., Murphy, P. M., and Jeang, K. T. (2000). Selective CXCR4 antagonism by Tat: Implication for in vivo expansion of coreceptor use by HIV-1. Proc. Natl. Acad. Sci. USA 97(21), 11466-11471.