FZD1 activates protein kinase C delta-mediated drug-resistance in multidrug-resistant MES-SA/Dx5 cancer cells

International Journal of Biochemistry and Cell Biology

Volumn 53, Issue , 2014, Pages 55-65

  Hung, Tsai Hsien ^a   Chen, Chuan Mu ^b   Tseng, Ching Ping ^a   Shen, Chih Jie ^b   Wang, Hui Ling ^a   Choo, Kong Bung ^c   Chong, Kowit Yu ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c UNIVERSITI TUNKU ABDUL RAHMAN   (Malaysia)

Author keywords

Apoptosis; Cell cycle; Multiple drug resistance; PKC delta; Rottelerin; shRNA

Indexed keywords

DOXORUBICIN; EARLY GROWTH RESPONSE FACTOR 1; FRIZZLED 1; FRIZZLED PROTEIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN C FOS; PROTEIN C JUN; PROTEIN KINASE C DELTA; ROTTLERIN; SCATTER FACTOR RECEPTOR; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; ABCB1 PROTEIN, HUMAN; FZD1 PROTEIN, HUMAN; MULTIDRUG RESISTANCE PROTEIN;

ARTICLE; CANCER CELL LINE; CANCER RESISTANCE; CELL PROLIFERATION; CELL VIABILITY; DOWN REGULATION; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; UTERUS SARCOMA; APOPTOSIS; BIOSYNTHESIS; DRUG EFFECTS; DRUG RESISTANCE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; SARCOMA; TUMOR CELL LINE; UTERINE NEOPLASMS;

APOPTOSIS; CELL LINE, TUMOR; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; FEMALE; FRIZZLED RECEPTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; P-GLYCOPROTEINS; PROTEIN KINASE C-DELTA; SARCOMA; SIGNAL TRANSDUCTION; UTERINE NEOPLASMS;

EID: 84901344077     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2014.04.011     Document Type: Article

References (80)

1. A. Abou-Kandil, R. Chamias, M. Huleihel, W.T. Godbey, and M. Aboud Differential role of PKC-induced c-Jun in HTLV-1 LTR activation by 12-O-tetradecanoylphorbol-13-acetate in different human T-cell lines PLoS One 7 2012 e29934
2. W.K. Aicher, K.M. Sakamoto, A. Hack, and H. Eibel Analysis of functional elements in the human Egr-1 gene promoter Rheumatol Int 18 1999 207 214 (Pubitemid 29294984)
3. O. Akutagawa, H. Nishi, S. Kyo, F. Terauchi, K. Yamazawa, and C. Higuma et al. Early growth response-1 mediates downregulation of telomerase in cervical cancer Cancer Sci 99 2008 1401 1406 (Pubitemid 351761730)
4. L.F. Al-Alem, L.A. McCord, R.C. Southard, M.W. Kilgore, and T.E. Curry Jr. Activation of the PKC pathway stimulates ovarian cancer cell proliferation migration, and expression of MMP7 and MMP10 Biol Reprod 89 2013 1 7
5. P. Angel, K. Hattori, T. Smeal, and M. Karin The jun proto-oncogene is positively autoregulated by its product Jun/AP-1 Cell 55 1988 875 885
6. J.F. Beck, D. Brügger, K. Brischwein, C. Liu, P. Bader, and D. Niethammer et al. Anticancer drug-mediated induction of multidrug resistance-associated genes and protein kinase C isozymes in the T-lymphoblastoid cell line CCRF-CEM and in blasts from patients with acute lymphoblastic leukemias Jpn J Cancer Res 92 2001 896 903 (Pubitemid 32894101)
7. C. Brodie, and P.M. Blumberg Regulation of cell apoptosis by protein kinase c delta Apoptosis 8 2003 19 27 (Pubitemid 36133134)
8. B. Chen, F. Jin, X.L. Lu, P.P. Wang, Y.P. Liu, and S.B. Wang Effect of PKC inhibitor on P-gp expression and drug-resistance in MGC803 cells Ai Zheng 23 2004 396 400
9. K.Y. Chong, C.C. Lai, and C.Y. Su Inducible and constitutive HSP70s confer synergistic resistance against metabolic challenges Biochem Biophys Res Commun 430 2013 774 779
10. A.S. Clark, K.A. West, P.M. Blumberg, and P.A. Dennis Altered protein kinase C (PKC) isoforms in non-small cell lung cancer cells: PKCdelta promotes cellular survival and chemotherapeutic resistance Cancer Res 63 2003 780 786 (Pubitemid 36231976)
11. S. Correa, R. Binato, B. Du Rocher, M.T. Castelo-Branco, L. Pizzatti, and E. Abdelhay Wnt/beta-catenin pathway regulates ABCB1 transcription in chronic myeloid leukemia BMC Cancer 12 2012 303
12. P.J. Daschner, H.P. Ciolino, C.A. Plouzek, and G.C. Yeh Increased AP-1 activity in drug resistant human breast cancer MCF-7 cells Breast Cancer Res Treat 53 1999 229 240 (Pubitemid 29209892)
13. M.I. Diaz Bessone, D.E. Berardi, P.B. Campodonico, L.B. Todaro, L. Lothstein, and E.D. Bal de Kier Joffe et al. Involvement of PKC delta (PKCdelta) in the resistance against different doxorubicin analogs Breast Cancer Res Treat 126 2011 577 587
14. M. Ehrlich DNA methylation in cancer: too much, but also too little Oncogene 21 2002 5400 5413 (Pubitemid 34983477)
15. H.A. El-Attar, and M.I. Sheta Hepatocyte growth factor profile with breast cancer Indian J Pathol Microbiol 54 2011 509 513
16. N. Fazlina, A. Maha, A.L. Zarina, A. Hamidah, S.Z. Zulkifli, and S.K. Cheong et al. Assessment of P-gp and MRP1 activities using MultiDrugQuant Assay Kit: a preliminary study of correlation between protein expressions and its functional activities in newly diagnosed acute leukaemia patients Malays J Pathol 30 2008 87 93
17. R.L. Fine, J. Patel, and B.A. Chabner Phorbol esters induce multidrug resistance in human breast cancer cells Proc Natl Acad Sci USA 85 1988 582 586 (Pubitemid 18059318)
18. M. Flahaut, R. Meier, A. Coulon, K.A. Nardou, F.K. Niggli, and D. Martinet et al. The Wnt receptor FZD1 mediates chemoresistance in neuroblastoma through activation of the Wnt/beta-catenin pathway Oncogene 28 2009 2245 2256
19. C. Gabler, S. Odau, K. Muller, J. Schon, A. Bondzio, and R. Einspanier Exploring cumulus-oocyte-complex-oviductal cell interactions: gene profiling in the bovine oviduct J Physiol Pharmacol 59 9 2008 29 42
20. K. Ganeshaguru, R.G. Wickremasinghe, D.T. Jones, M. Gordon, S.M. Hart, and A.E. Virchis et al. Actions of the selective protein kinase C inhibitor PKC412 on B-chronic lymphocytic leukemia cells in vitro Haematologica 87 2002 167 176 (Pubitemid 34160623)
21. P.K. Gill, A. Gescher, and T.W. Gant Regulation of MDR1 promoter activity in human breast carcinoma cells by protein kinase C isozymes alpha and theta Eur J Biochem 268 2001 4151 4157 (Pubitemid 32862875)
22. M.P. Gosland, B.L. Lum, and B.I. Sikic Reversal by cefoperazone of resistance to etoposide, doxorubicin, and vinblastine in multidrug resistant human sarcoma cells Cancer Res 49 1989 6901 6905 (Pubitemid 20016564)
23. A. Gonelli, C. Mischiati, R. Guerrini, R. Voltan, S. Salvadori, and G. Zauli Perspectives of protein kinase C (PKC) inhibitors as anti-cancer agents Mini Rev Med Chem 9 2009 498 509
24. J. Gregg, and G. Fraizer Transcriptional regulation of EGR1 by EGF and the ERK signaling pathway in prostate cancer cells Genes Cancer 2 2011 900 909
25. M. Gschwendt, H.J. Muller, K. Kielbassa, R. Zang, W. Kittstein, and G. Rincke et al. Rottlerin, a novel protein kinase inhibitor Biochem Biophys Res Commun 199 1994 93 98 (Pubitemid 24179919)
26. W.G. Harker, and B.I. Sikic Multidrug (pleiotropic) resistance in doxorubicin-selected variants of the human sarcoma cell line MES-SA Cancer Res 45 1985 4091 4096 (Pubitemid 16224856)
27. W.G. Harker, D. Bauer, B.B. Etiz, R.A. Newman, and B.I. Sikic Verapamil-mediated sensitization of doxorubicin-selected pleiotropic resistance in human sarcoma cells: selectivity for drugs which produce DNA scission Cancer Res 46 1986 2369 2373 (Pubitemid 16120698)
28. S. Hirai, Y. Izumi, K. Higa, K. Kaibuchi, K. Mizuno, and S. Osada et al. Ras-dependent signal transduction is indispensable but not sufficient for the activation of AP1/Jun by PKC delta EMBO J 13 1994 2331 2340 (Pubitemid 24157608)
29. A. Holleman, I. Chung, R.R. Olsen, B. Kwak, A. Mizokami, and N. Saijo et al. miR-135a contributes to paclitaxel resistance in tumor cells both in vitro and in vivo Oncogene 30 2011 4386 4398
30. E. Hoffmann, J. Ashouri, S. Wolter, A. Doerrie, O. Dittrich-Breiholz, and H. Schneider et al. Transcriptional regulation of EGR-1 by the interleukin-1-JNK-MKK7-c-Jun pathway J Biol Chem 283 2008 12120 12128
31. R.F. Holcombe, J.L. Marsh, M.L. Waterman, F. Lin, T. Milovanovic, and T. Truong Expression of Wnt ligands and frizzled receptors in colonic mucosa and in colon carcinoma Mol Pathol 55 2002 220 226
32. M. Hu, Y. Liu, C. Deng, R. Han, Y. Jia, and S. Liu et al. Enhanced invasiveness in multidrug resistant leukemic cells is associated with overexpression of P-glycoprotein and cellular inhibitor of apoptosis protein Leuk Lymphoma 52 2011 1302 1311
33. Y.P. Hu, and J. Robert Inhibition of protein kinase C in multidrug-resistant cells by modulators of multidrug resistance J Cancer Res Clin Oncol 123 1997 201 210 (Pubitemid 27243566)
34. K.R. Hughes, F. Sablitzky, and Y.R. Mahida Expression profiling of Wnt family of genes in normal and inflammatory bowel disease primary human intestinal myofibroblasts and normal human colonic crypt epithelial cells Inflamm Bowel Dis 17 2011 213 220
35. C.L. Huang, J.C. Cheng, K. Kitajima, T. Nakano, C.F. Yeh, and K.Y. Chong et al. Disabled-2 is required for mesoderm differentiation of murine embryonic stem cells J Cell Physiol 225 2010 92 105
36. T.T. Huang, K.Y. Chong, D.M. Ojcius, Y.H. Wu, Y.F. Ko, and C.Y. Wu et al. Hirsutella sinensis mycelium suppresses interleukin-1β and interleukin-18 secretion by inhibiting both canonical and non-canonical inflammasomes Sci Rep 3 2013 1374
37. R.I. James, J. Menaya, K. Hudson, V. Devalia, J. Ryves, and F.J. Evans et al. Role of protein kinase C in induction of gene expression and inhibition of cell proliferation by interferon alpha Eur J Biochem 209 1992 813 822
38. H. Jin, A. Kanthasamy, V. Anantharam, A. Rana, and A.G. Kanthasamy Transcriptional regulation of pro-apoptotic protein kinase Cdelta: implications for oxidative stress-induced neuronal cell death J Biol Chem 286 2011 19840 19859
39. S.C. Kiley, K.J. Clark, S.K. Duddy, D.R. Welch, and S. Jaken Increased protein kinase C delta in mammary tumor cells: relationship to transformtion and metastatic progression Oncogene 18 1999 6748 6757
40. S.C. Kiley, K.J. Clark, M. Goodnough, D.R. Welch, and S. Jaken Protein kinase C delta involvement in mammary tumor cell metastasis Cancer Res 59 1999 3230 3238 (Pubitemid 29316027)
41. N. Kinoshita, H. Iioka, A. Miyakoshi, and N. Ueno PKC delta is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements Genes Dev 17 2003 1663 1676 (Pubitemid 36828792)
42. N. Kotelevets, D. Fabbro, A. Huwiler, and U. Zangemeister-Wittke Targeting sphingosine kinase 1 in carcinoma cells decreases proliferation and survival by compromising PKC activity and cytokinesis PLoS One 7 2012 e39209
43. S. Labialle, L. Gayet, E. Marthinet, D. Rigal, and L.G. Baggetto Transcriptional regulators of the human multidrug resistance 1 gene: recent views Biochem Pharmacol 64 2002 943 948 (Pubitemid 35232268)
44. S.K. Lee, A. Shehzad, J.C. Jung, J.K. Sonn, J.T. Lee, and J.W. Park et al. Protein kinase Calpha protects against multidrug resistance in human colon cancer cells Mol Cells 34 2012 61 69
45. Z. Li, N. Wang, J. Fang, J. Huang, F. Tian, and C. Li et al. Role of PKC-ERK signaling in tamoxifen-induced apoptosis and tamoxifen resistance in human breast cancer cells Oncol Rep 27 2012 1879 1886
46. J.H. Lim, S.M. Woo, K.J. Min, E.J. Park, J.H. Jang, and B.R. Seo et al. Rottlerin induces apoptosis of HT29 colon carcinoma cells through NAG-1 upregulation via an ERK and p38 MAPK-dependent and PKC delta-independent mechanism Chem Biol Interact 197 2012 1 7
47. C.W. Lin, W.C. Hou, S.C. Shen, S.H. Juan, C.H. Ko, and L.M. Wang et al. Quercetin inhibition of tumor invasion via suppressing PKC delta/ERK/AP-1- dependent matrix metalloproteinase-9 activation in breast carcinoma cells Carcinogenesis 29 2008 1807 1815
48. T. Liu, C.Z. Kong, J.B. Bi, and G.F. Liu Mechanism of reversal of multidrug resistance in human renal carcinoma cells by protein kinase C inhibitor Zhonghua Zhong Liu Za Zhi 28 2006 92 95
49. H.J. Mackay, and C.J. Twelves Targeting the protein kinase C family: are we there yet? Nat Rev Cancer 7 2007 554 562 (Pubitemid 46985395)
50. G. Martiny-Baron, M.G. Kazanietz, H. Mischak, P.M. Blumberg, G. Kochs, and H. Hug et al. Selective inhibition of protein kinase C isozymes by the indolocarbazole Go 6976 J Biol Chem 268 1993 9194 9197 (Pubitemid 23145960)
51. R. Mazzanti, F. Platini, C. Bottini, O. Fantappie, M. Solazzo, and L. Tessitore Down-regulation of the HGF/MET autocrine loop induced by celecoxib and mediated by P-gp in MDR-positive human hepatocellular carcinoma cell line Biochem Pharmacol 78 2009 21 32
52. C. McCoy, D.E. Smith, and M.M. Cornwell 12-O-tetradecanoylphorbol-13- acetate activation of the MDR1 promoter is mediated by EGR1 Mol Cell Biol 15 1995 6100 6108
53. E. McKiernan, K. O'Brien, N. Grebenchtchikov, A. Geurts-Moespot, A.M. Sieuwerts, and J.W. Martens et al. Protein kinase Cdelta expression in breast cancer as measured by real-time PCR, western blotting and ELISA Br J Cancer 99 2008 1644 1650
54. T. Milovanovic, K. Planutis, A. Nguyen, J.L. Marsh, F. Lin, and C. Hope et al. Expression of Wnt genes and frizzled 1 and 2 receptors in normal breast epithelium and infiltrating breast carcinoma Int J Oncol 25 2004 1337 1342
55. S. Movassaghian, H.R. Moghimi, F.H. Shirazi, A. Koshkaryev, M.S. Trivedi, and V.P. Torchilin Efficient down-regulation of PKC-alpha gene expression in A549 lung cancer cells mediated by antisense oligodeoxynucleotides in dendrosomes Int J Pharm 441 2013 82 91
56. S.M. Nabha, S. Glaros, M. Hong, A.E. Lykkesfeldt, R. Schiff, and K. Osborne et al. Upregulation of PKC-delta contributes to antiestrogen resistance in mammary tumor cells Oncogene 24 2005 3166 3176 (Pubitemid 40695085)
57. Y. Nishizuka, and U. Kikkawa Early studies of protein kinase C: a historical perspective Methods Mol Biol 233 2003 9 18
58. C.A. O'Brian, N.E. Ward, J.R. Stewart, and F. Chu Prospects for targeting protein kinase C isozymes in the therapy of drug-resistant cancer - an evolving story Cancer Metastasis Rev 20 2001 95 100 (Pubitemid 34074684)
59. R. Ouelaa-Benslama, O. De Wever, A. Hendrix, M. Sabbah, K. Lambein, and D. Land et al. Identification of a GalphaGbetagamma AKT and PKCalpha signalome associated with invasive growth in two genetic models of human breast cancer cell epithelial-to-mesenchymal transition Int J Oncol 41 2012 189 200
60. P. Sassone-Corsi, J.C. Sisson, and I.M. Verma Transcriptional autoregulation of the proto-oncogene fos Nature 334 1988 314 319
61. M. Sattler, M.M. Reddy, R. Hasina, T. Gangadhar, and R. Salgia The role of the c-Met pathway in lung cancer and the potential for targeted therapy Ther Adv Med Oncol 3 2011 171 184
62. S. Schnickmann, D. Camacho-Trullio, M. Bissinger, R. Eils, P. Angel, and P. Schirmacher et al. AP-1-controlled hepatocyte growth factor activation promotes keratinocyte migration via CEACAM1 and urokinase plasminogen activator/urokinase plasminogen receptor J Invest Dermatol 129 2009 1140 1148
63. C.J. Shen, W.T. Cheng, S.C. Wu, H.L. Chen, T.C. Tsai, and S.H. Yang et al. Differential differences in methylation status of putative imprinted genes among cloned swine genomes PLoS One 7 2012 e32812
64. Y.Q. Shi, X.J. Qu, Y.X. Liao, C.F. Xie, Y.N. Cheng, and S. Li et al. Reversal effect of a macrocyclic bisbibenzyl plagiochin E on multidrug resistance in adriamycin-resistant K562/A02 cells Eur J Pharmacol 584 2008 66 71
65. J. Sigmond, A.M. Bergman, L.G. Leon, W.J. Loves, E.K. Hoebe, and G.J. Peters Staurosporine increases toxicity of gemcitabine in non-small cell lung cancer cells: role of protein kinase C, deoxycytidine kinase and ribonucleotide reductase Anticancer Drugs 21 2010 591 599
66. P.K. Singh, M.E. Behrens, J.P. Eggers, R.L. Cerny, J.M. Bailey, and K. Shanmugam et al. Phosphorylation of MUC1 by Met modulates interaction with p53 and MMP1 expression J Biol Chem 283 2008 26985 26995
67. O. Sokolova, M. Vieth, and M. Naumann Protein kinase C isozymes regulate matrix metalloproteinase-1 expression and cell invasion in Helicobacter pylori infection Gut 62 2013 358 367
68. U. Stein, C. Fleuter, F. Siegel, J. Smith, A. Kopacek, and D.A. Scudiero et al. Impact of mutant beta-catenin on ABCB1 expression and therapy response in colon cancer cells Br J Cancer 106 2012 1395 1405
69. J. Sun, C.A. Yeung, N.N. Co, T.Y. Tsang, E. Yau, and K. Luo et al. Clitocine reversal of P-glycoprotein associated multi-drug resistance through down-regulation of transcription factor NF-kappaB in R-HepG2 cell line PLoS One 7 2012 e40720
70. K. Svensson, and C. Larsson A protein kinase Cbeta inhibitor attenuates multidrug resistance of neuroblastoma cells BMC Cancer 3 2003 10
71. M. Tomita, Y. Tanaka, and N. Mori MicroRNA miR-146a is induced by HTLV-1 tax and increases the growth of HTLV-1-infected T-cells Int J Cancer 130 2012 2300 2309
72. W.C. Tseng, W.C. Yang, A.H. Yang, S.L. Hsieh, and D.C. Tarng Expression of TNFRSF6B in kidneys is a novel predictor for progression of chronic kidney disease Mod Pathol 26 2013 984 994
73. Q. Wang, H. Salman, M. Danilenko, and G.P. Studzinski Cooperation between antioxidants and 1,25-dihydroxyvitamin D3 in induction of leukemia HL60 cell differentiation through the JNK/AP-1/Egr-1 pathway J Cell Physiol 204 2005 964 974 (Pubitemid 41099283)
74. K.J. Way, E. Chou, and G.L. King Identification of PKC-isoform-specific biological actions using pharmacological approaches Trends Pharmacol Sci 21 2000 181 187 (Pubitemid 30243200)
75. S.E. Wilkinson, P.J. Parker, and J.S. Nixon Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C Biochem J 294 1993 335 337 (Pubitemid 23268828)
76. C. Yan, M.S. Jamaluddin, B. Aggarwal, J. Myers, and D.D. Boyd Gene expression profiling identifies activating transcription factor 3 as a novel contributor to the proapoptotic effect of curcumin Mol Cancer Ther 4 2005 233 241 (Pubitemid 40340203)
77. S.F. Yang, M.K. Chen, Y.S. Hsieh, T.T. Chung, Y.H. Hsieh, and C.W. Lin et al. Prostaglandin E2/EP1 signaling pathway enhances intercellular adhesion molecule 1 (ICAM-1) expression and cell motility in oral cancer cells J Biol Chem 285 2010 29808 29816
78. T. Yokochi, and K.D. Robertson Doxorubicin inhibits DNMT1, resulting in conditional apoptosis Mol Pharmacol 66 2004 1415 1420 (Pubitemid 39564768)
79. H. Zhang, X. Zhang, X. Wu, W. Li, P. Su, and H. Cheng et al. Interference of Frizzled 1 (FZD1) reverses multidrug resistance in breast cancer cells through the Wnt/beta-catenin pathway Cancer Lett 323 2012 106 113
80. L. Zheng, J. Pu, G. Jiang, M. Weng, J. He, and H. Mei et al. Abnormal expression of early growth response 1 in gastric cancer: association with tumor invasion, metastasis and heparanase transcription Pathol Int 60 2010 268 277