메뉴 건너뛰기




Volumn 64, Issue 5-6, 2002, Pages 943-948

Transcriptional regulators of the human multidrug resistance 1 gene: Recent views

Author keywords

hMDR1 gene; Multidrug resistance; P glycoprotein; Transcriptional regulation

Indexed keywords

MULTIDRUG RESISTANCE PROTEIN 1; TRANSCRIPTION FACTOR;

EID: 0036710923     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)01156-5     Document Type: Article
Times cited : (156)

References (62)
  • 1
    • 0014290206 scopus 로고
    • Uptake and retention of daunomycin by mouse leukemic cells as factors in drug response
    • Kessel D., Botterill V., Wodinsky I. Uptake and retention of daunomycin by mouse leukemic cells as factors in drug response. Cancer Res. 28:1968;938-941.
    • (1968) Cancer Res. , vol.28 , pp. 938-941
    • Kessel, D.1    Botterill, V.2    Wodinsky, I.3
  • 2
    • 0015893137 scopus 로고
    • Active outward transport of daunomycin in resistant ehrlich ascites tumor cells
    • Danø K. Active outward transport of daunomycin in resistant ehrlich ascites tumor cells. Biochim. Biophys. Acta. 323:1973;466-483.
    • (1973) Biochim. Biophys. Acta. , vol.323 , pp. 466-483
    • Danø, K.1
  • 3
    • 33645830172 scopus 로고
    • Surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
    • Juliano R.L., Ling V.A. Surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim. Biophys. Acta. 455:1976;152-162.
    • (1976) Biochim. Biophys. Acta , vol.455 , pp. 152-162
    • Juliano, R.L.1    Ling, V.A.2
  • 4
    • 0030971840 scopus 로고    scopus 로고
    • Structure of the multidrug resistant P-glycoprotein to 2.5 nm resolution determined by electron microscopy and image analysis
    • Rosenberg M.F., Callaghan R., Ford R.C., Higgins C.F. Structure of the multidrug resistant P-glycoprotein to 2.5 nm resolution determined by electron microscopy and image analysis. J. Biol. Chem. 272:1997;10685-10694.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10685-10694
    • Rosenberg, M.F.1    Callaghan, R.2    Ford, R.C.3    Higgins, C.F.4
  • 5
    • 0032574948 scopus 로고    scopus 로고
    • Secondary structure of P-glycoprotein from circular dichroism and prediction from its sequence
    • Dong M., Ladavière L., Deleage G., Penin F., Baggetto L.G. Secondary structure of P-glycoprotein from circular dichroism and prediction from its sequence. Biochim. Biophys. Acta. 1371:1998;317-334.
    • (1998) Biochim. Biophys. Acta , vol.1371 , pp. 317-334
    • Dong, M.1    Ladavière, L.2    Deleage, G.3    Penin, F.4    Baggetto, L.G.5
  • 7
    • 0001607723 scopus 로고
    • Distantly related sequences in the α- and β-subunits of ATPsynthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
    • Walker J.E., Saraste M., Runswick M.J., Gay N.J. Distantly related sequences in the α- and β-subunits of ATPsynthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J. 1:1982;945-951.
    • (1982) EMBO J. , vol.1 , pp. 945-951
    • Walker, J.E.1    Saraste, M.2    Runswick, M.J.3    Gay, N.J.4
  • 9
    • 0023006005 scopus 로고
    • Isolation and expression of a complementary DNA that confers multidrug resistance
    • Gros P., Ben Neriah Y.B., Croop J.M., Housman D.E. Isolation and expression of a complementary DNA that confers multidrug resistance. Nature. 323:1986;728-731.
    • (1986) Nature , vol.323 , pp. 728-731
    • Gros, P.1    Ben Neriah, Y.B.2    Croop, J.M.3    Housman, D.E.4
  • 10
    • 0022457103 scopus 로고
    • Human multidrug-resistant cell lines: Increased mdr1 expression can precede gene amplification
    • Shen D.W., Fojo A., Chin J.E., Roninson I.B., Richert N., Pastan I., Gottesman M.M. Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification. Science. 232:1986;643-645.
    • (1986) Science , vol.232 , pp. 643-645
    • Shen, D.W.1    Fojo, A.2    Chin, J.E.3    Roninson, I.B.4    Richert, N.5    Pastan, I.6    Gottesman, M.M.7
  • 12
    • 0022979328 scopus 로고
    • Differential amplification and disproportionate expression of five genes in three multidrug-resistant Chinese hamster lung cell lines
    • de Bruijn M.H.L., Van der Bliek A.M., Biedler J.L., Borst P. Differential amplification and disproportionate expression of five genes in three multidrug-resistant Chinese hamster lung cell lines. Mol. Cell Biol. 6:1986;4717-4722.
    • (1986) Mol. Cell Biol. , vol.6 , pp. 4717-4722
    • De Bruijn, M.H.L.1    Van der Bliek, A.M.2    Biedler, J.L.3    Borst, P.4
  • 13
    • 0023522193 scopus 로고
    • Isolation and sequence of the promoter region of the human multidrug resistance (P-glycoprotein) gene
    • Ueda K., Pastan I., Gottesman M.M. Isolation and sequence of the promoter region of the human multidrug resistance (P-glycoprotein) gene. J. Biol. Chem. 262:1987;17432-17436.
    • (1987) J. Biol. Chem. , vol.262 , pp. 17432-17436
    • Ueda, K.1    Pastan, I.2    Gottesman, M.M.3
  • 15
    • 0001259013 scopus 로고    scopus 로고
    • Transcriptional regulation of multidrug-resistant genes
    • Ince T.A., Scotto K.W. Transcriptional regulation of multidrug-resistant genes. Encyclopedia of cancer. III:1997;1751-1764.
    • (1997) Encyclopedia of cancer , vol.3 , pp. 1751-1764
    • Ince, T.A.1    Scotto, K.W.2
  • 16
    • 0027410016 scopus 로고
    • Identification of a functional initiator sequence in the human MDR1 promoter
    • Van Groenigen M., Valentijn L.J., Baas F. Identification of a functional initiator sequence in the human MDR1 promoter. Biochim. Biophys. Acta. 1172:1993;138-146.
    • (1993) Biochim. Biophys. Acta , vol.1172 , pp. 138-146
    • Van Groenigen, M.1    Valentijn, L.J.2    Baas, F.3
  • 17
    • 0028153702 scopus 로고
    • DNA sequence requirements for transcriptional initiator activity in mammalian cells
    • Javahery R., Khachi A., Lo K., Zenzie-Gregory B., Smale S.T. DNA sequence requirements for transcriptional initiator activity in mammalian cells. Mol. Cell Biol. 14:1994;116-127.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 116-127
    • Javahery, R.1    Khachi, A.2    Lo, K.3    Zenzie-Gregory, B.4    Smale, S.T.5
  • 18
    • 0024557039 scopus 로고
    • The "initiator" as a transcription control element
    • Smale S.T., Baltimore D. The "initiator" as a transcription control element. Cell. 57:1989;103-113.
    • (1989) Cell , vol.57 , pp. 103-113
    • Smale, S.T.1    Baltimore, D.2
  • 19
    • 0027290898 scopus 로고
    • Sp1 activates the MDR1 promoter through one of the two distinct G-rich regions that modulate promoter activity
    • Cornwell M.M., Smith D.E. Sp1 activates the MDR1 promoter through one of the two distinct G-rich regions that modulate promoter activity. J. Biol. Chem. 268:1993;19505-19511.
    • (1993) J. Biol. Chem. , vol.268 , pp. 19505-19511
    • Cornwell, M.M.1    Smith, D.E.2
  • 20
  • 21
    • 0028820126 scopus 로고
    • TPA activation of the MDR1 promoter is mediated by EGR-1
    • McCoy C., Smith D.E., Cornwell M.M. TPA activation of the MDR1 promoter is mediated by EGR-1. Mol. Cell Biol. 15:1995;6100-6108.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 6100-6108
    • McCoy, C.1    Smith, D.E.2    Cornwell, M.M.3
  • 22
    • 0033021651 scopus 로고    scopus 로고
    • The Wilms' tumor suppressor WT1 inhibits 12-O-tetradecanoylphorbol-13-acetate activation of the multidrug resistance-1 promoter
    • McCoy C., McGee S.B., Cornwell M.M. The Wilms' tumor suppressor WT1 inhibits 12-O-tetradecanoylphorbol-13-acetate activation of the multidrug resistance-1 promoter. Cell Growth Differ. 10:1999;377-386.
    • (1999) Cell Growth Differ , vol.10 , pp. 377-386
    • McCoy, C.1    McGee, S.B.2    Cornwell, M.M.3
  • 23
    • 0027384536 scopus 로고
    • Inhibition of colony-stimulating factor-1 promoter activity by the product of the Wilms' tumor locus
    • Harrington M.A., Konicek B., Song A., Xia X.L., Fredericks W.J., Rauscher F.J III Inhibition of colony-stimulating factor-1 promoter activity by the product of the Wilms' tumor locus. J. Biol. Chem. 268:1993;21271-21275.
    • (1993) J. Biol. Chem. , vol.268 , pp. 21271-21275
    • Harrington, M.A.1    Konicek, B.2    Song, A.3    Xia, X.L.4    Fredericks, W.J.5    Rauscher F.J. III6
  • 25
    • 0029788450 scopus 로고    scopus 로고
    • Role of the human Y box-binding protein YB-1 in cellular sensitivity to the DNA-damaging agents cisplatin, mitomycin C, and ultraviolet light
    • Ohga T., Koike K., Ono M., Makino Y., Itagaki Y., Tanimoto M., Kuwano M., Kohno K. Role of the human Y box-binding protein YB-1 in cellular sensitivity to the DNA-damaging agents cisplatin, mitomycin C, and ultraviolet light. Cancer Res. 56:1996;4224-4228.
    • (1996) Cancer Res. , vol.56 , pp. 4224-4228
    • Ohga, T.1    Koike, K.2    Ono, M.3    Makino, Y.4    Itagaki, Y.5    Tanimoto, M.6    Kuwano, M.7    Kohno, K.8
  • 26
    • 0030922309 scopus 로고    scopus 로고
    • DNA elements recognizing NF-Y and Sp1 regulate the human multidrug-resistance gene promoter
    • Sundseth R., MacDonald G., King A.C. DNA elements recognizing NF-Y and Sp1 regulate the human multidrug-resistance gene promoter. Mol. Pharmacol. 51:1997;963-971.
    • (1997) Mol. Pharmacol. , vol.51 , pp. 963-971
    • Sundseth, R.1    MacDonald, G.2    King, A.C.3
  • 27
    • 0031861729 scopus 로고    scopus 로고
    • Transcriptional regulation of the MDR1 gene by histone acetyltransferase/deacetylase is mediated by NF-Y
    • Jin S., Scotto K.W. Transcriptional regulation of the MDR1 gene by histone acetyltransferase/deacetylase is mediated by NF-Y. Mol. Cell Biol. 18:1998;4377-4384.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 4377-4384
    • Jin, S.1    Scotto, K.W.2
  • 28
    • 0034723353 scopus 로고    scopus 로고
    • Transcriptional activation of the MDR1 gene by UV irradiation. Role of NF-Y and Sp1
    • Hu Z., Jin S., Scotto K.W. Transcriptional activation of the MDR1 gene by UV irradiation. Role of NF-Y and Sp1. J. Biol. Chem. 275:2000;2979-2985.
    • (2000) J. Biol. Chem. , vol.275 , pp. 2979-2985
    • Hu, Z.1    Jin, S.2    Scotto, K.W.3
  • 29
    • 0028409179 scopus 로고
    • Structural and functional properties of the evolutionarily ancient Y-box family of nucleic acid binding proteins
    • Wolffe A.P. Structural and functional properties of the evolutionarily ancient Y-box family of nucleic acid binding proteins. Bioessays. 16:1994;245-251.
    • (1994) Bioessays , vol.16 , pp. 245-251
    • Wolffe, A.P.1
  • 30
    • 0035976989 scopus 로고    scopus 로고
    • The major messenger ribonucleoprotein particle protein p50 (YB-1) promotes nucleic acid strand annealing
    • Skabkin M.A., Evdokimova V., Thomas A.A., Ovchinnikov L.P. The major messenger ribonucleoprotein particle protein p50 (YB-1) promotes nucleic acid strand annealing. J. Biol. Chem. 276:2001;44841-44847.
    • (2001) J. Biol. Chem. , vol.276 , pp. 44841-44847
    • Skabkin, M.A.1    Evdokimova, V.2    Thomas, A.A.3    Ovchinnikov, L.P.4
  • 32
    • 0032966918 scopus 로고    scopus 로고
    • Interaction between the two ubiquitously expressed transcription factors NF-Y and Sp1
    • Roder K., Wolf S.S., Larkin K.J., Schweizer M. Interaction between the two ubiquitously expressed transcription factors NF-Y and Sp1. Gene. 234:1999;61-69.
    • (1999) Gene , vol.234 , pp. 61-69
    • Roder, K.1    Wolf, S.S.2    Larkin, K.J.3    Schweizer, M.4
  • 33
    • 0030743394 scopus 로고    scopus 로고
    • CCAAT-binding factor NF-Y and RFX are required for in vivo assembly of a nucleoprotein complex that spans 250 base pairs: The invariant chain promoter as a model
    • Linhoff M.W., Wright K.L., Ting J.P. CCAAT-binding factor NF-Y and RFX are required for in vivo assembly of a nucleoprotein complex that spans 250 base pairs: the invariant chain promoter as a model. Mol. Cell Biol. 17:1997;4589-4596.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 4589-4596
    • Linhoff, M.W.1    Wright, K.L.2    Ting, J.P.3
  • 34
    • 0032030308 scopus 로고    scopus 로고
    • A survey of 178 NF-Y binding CCAAT boxes
    • Mantovani R. A survey of 178 NF-Y binding CCAAT boxes. Nucleic Acids Res. 26:1998;1135-1143.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 1135-1143
    • Mantovani, R.1
  • 35
    • 0028109125 scopus 로고
    • Transactivation of the human multidrug resistance (MDR1) gene promoter by p53 mutants
    • Nguyen K.T., Liu B., Ueda K., Gottesman M.M., Pastan I., Chin K.V. Transactivation of the human multidrug resistance (MDR1) gene promoter by p53 mutants. Oncol. Res. 6:1994;71-77.
    • (1994) Oncol. Res. , vol.6 , pp. 71-77
    • Nguyen, K.T.1    Liu, B.2    Ueda, K.3    Gottesman, M.M.4    Pastan, I.5    Chin, K.V.6
  • 36
    • 0026555717 scopus 로고
    • Modulation of the activity of the promoter of the human MDR1 gene by Ras and p53
    • Chin K.V., Ueda K., Pastan I., Gottesman M.M. Modulation of the activity of the promoter of the human MDR1 gene by Ras and p53. Science. 255:1992;459-462.
    • (1992) Science , vol.255 , pp. 459-462
    • Chin, K.V.1    Ueda, K.2    Pastan, I.3    Gottesman, M.M.4
  • 37
    • 0035920197 scopus 로고    scopus 로고
    • Transcriptional repression by p53 through direct binding to a novel DNA element
    • Johnson R.A., Ince T.A., Scotto K.W. Transcriptional repression by p53 through direct binding to a novel DNA element. J. Biol. Chem. 276:2001;27716-27720.
    • (2001) J. Biol. Chem. , vol.276 , pp. 27716-27720
    • Johnson, R.A.1    Ince, T.A.2    Scotto, K.W.3
  • 39
    • 0028939453 scopus 로고
    • Wild type p53 stimulates expression from the human multidrug resistance promoter in a p53-negative cell line
    • Goldsmith M.E., Gudas J.M., Schneider E., Cowan K.H. Wild type p53 stimulates expression from the human multidrug resistance promoter in a p53-negative cell line. J. Biol. Chem. 270:1995;1894-1898.
    • (1995) J. Biol. Chem. , vol.270 , pp. 1894-1898
    • Goldsmith, M.E.1    Gudas, J.M.2    Schneider, E.3    Cowan, K.H.4
  • 40
    • 0033552638 scopus 로고    scopus 로고
    • Twenty years of p53 research: Structural and functional aspects of the p53 protein
    • May P., May E. Twenty years of p53 research: structural and functional aspects of the p53 protein. Oncogene. 18:1999;7621-7636.
    • (1999) Oncogene , vol.18 , pp. 7621-7636
    • May, P.1    May, E.2
  • 42
    • 0033573850 scopus 로고    scopus 로고
    • Negative regulation of MDR1 promoter activity in MCF-7 but not in multidrug resistant MCF-7/Adr cells by cross-coupled NF-kappa B/p65 and c-Fos transcription factors and their interaction with the CAAT region
    • Ogretmen B., Safa A.R. Negative regulation of MDR1 promoter activity in MCF-7 but not in multidrug resistant MCF-7/Adr cells by cross-coupled NF-kappa B/p65 and c-Fos transcription factors and their interaction with the CAAT region. Biochemistry. 38:1999;2189-2199.
    • (1999) Biochemistry , vol.38 , pp. 2189-2199
    • Ogretmen, B.1    Safa, A.R.2
  • 43
    • 0028149768 scopus 로고
    • NF-IL6 a member of the C/EBP family of transcription factors binds and trans-activates the human MDR1 gene promoter
    • Combates N.J., Rzepka R.W., Chen Y.N., Cohen D. NF-IL6 a member of the C/EBP family of transcription factors binds and trans-activates the human MDR1 gene promoter. J. Biol. Chem. 269:1994;29715-29719.
    • (1994) J. Biol. Chem. , vol.269 , pp. 29715-29719
    • Combates, N.J.1    Rzepka, R.W.2    Chen, Y.N.3    Cohen, D.4
  • 44
    • 0025060257 scopus 로고
    • Heat shock and arsenite increase expression of the multidrug resistance (MDR1) gene in human renal carcinoma cells
    • Chin K.V., Tanaka S., Darlington G., Pastan I., Gottesman M.M. Heat shock and arsenite increase expression of the multidrug resistance (MDR1) gene in human renal carcinoma cells. J. Biol. Chem. 265:1990;221-226.
    • (1990) J. Biol. Chem. , vol.265 , pp. 221-226
    • Chin, K.V.1    Tanaka, S.2    Darlington, G.3    Pastan, I.4    Gottesman, M.M.5
  • 45
    • 0026598039 scopus 로고
    • Heat-shock responsive elements in the induction of the multidrug resistance gene (MDR1)
    • Kioka N., Yamano Y., Komano T., Ueda K. Heat-shock responsive elements in the induction of the multidrug resistance gene (MDR1). FEBS Lett. 301:1992;37-40.
    • (1992) FEBS Lett. , vol.301 , pp. 37-40
    • Kioka, N.1    Yamano, Y.2    Komano, T.3    Ueda, K.4
  • 47
    • 0034637516 scopus 로고    scopus 로고
    • Regulation of multidrug resistance 1 (MDR1)/P-glycoprotein gene expression and activity by heat-shock transcription factor 1 (HSF1)
    • Vilaboa N.E., Galan A., Troyano A., de Blas E., Aller P. Regulation of multidrug resistance 1 (MDR1)/P-glycoprotein gene expression and activity by heat-shock transcription factor 1 (HSF1). J. Biol. Chem. 275:2000;24970-24976.
    • (2000) J. Biol. Chem. , vol.275 , pp. 24970-24976
    • Vilaboa, N.E.1    Galan, A.2    Troyano, A.3    De Blas, E.4    Aller, P.5
  • 48
    • 0032830931 scopus 로고    scopus 로고
    • TCF transcription factors: Molecular switches in carcinogenesis
    • Roose J., Clevers H. TCF transcription factors: molecular switches in carcinogenesis. Biochim. Biophys. Acta. 1424:1999;M23-37.
    • (1999) Biochim. Biophys. Acta , vol.1424
    • Roose, J.1    Clevers, H.2
  • 49
    • 0032963355 scopus 로고    scopus 로고
    • Dermal fibroblast proliferation is improved by beta-catenin overexpression and inhibited by E-cadherin expression
    • Soler C., Grangeasse C., Baggetto L.G., Damour O. Dermal fibroblast proliferation is improved by beta-catenin overexpression and inhibited by E-cadherin expression. FEBS Lett. 442:1999;178-182.
    • (1999) FEBS Lett. , vol.442 , pp. 178-182
    • Soler, C.1    Grangeasse, C.2    Baggetto, L.G.3    Damour, O.4
  • 50
    • 0034282519 scopus 로고    scopus 로고
    • Transactivation of the multidrug resistance 1 gene by T-cell factor 4/beta-catenin complex in early colorectal carcinogenesis
    • Yamada T., Takaoka A.S., Naishiro Y., Hayashi R., Maruyama K., Maesawa C., Ochiai A., Hirohashi S. Transactivation of the multidrug resistance 1 gene by T-cell factor 4/beta-catenin complex in early colorectal carcinogenesis. Cancer Res. 60:2000;4761-4766.
    • (2000) Cancer Res. , vol.60 , pp. 4761-4766
    • Yamada, T.1    Takaoka, A.S.2    Naishiro, Y.3    Hayashi, R.4    Maruyama, K.5    Maesawa, C.6    Ochiai, A.7    Hirohashi, S.8
  • 51
    • 0035805536 scopus 로고    scopus 로고
    • Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin
    • Geick A., Eichelbaum M., Burk O. Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin. J. Biol. Chem. 276:2001;14581-14587.
    • (2001) J. Biol. Chem. , vol.276 , pp. 14581-14587
    • Geick, A.1    Eichelbaum, M.2    Burk, O.3
  • 52
    • 0035038919 scopus 로고    scopus 로고
    • The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux
    • Synold T.W., Dussault I., Forman B.M. The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux. Nat. Med. 7:2001;584-590.
    • (2001) Nat. Med. , vol.7 , pp. 584-590
    • Synold, T.W.1    Dussault, I.2    Forman, B.M.3
  • 53
    • 0026480859 scopus 로고
    • Purification and characterization of NF-R1 that regulates the expression of the human multidrug resistance (MDR1) gene
    • Ogura M., Takatori T., Tsuruo T. Purification and characterization of NF-R1 that regulates the expression of the human multidrug resistance (MDR1) gene. Nucleic Acids Res. 20:1992;5811-5817.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 5811-5817
    • Ogura, M.1    Takatori, T.2    Tsuruo, T.3
  • 54
    • 0027509823 scopus 로고
    • Purification and characterization of NF-R2 that regulates the expression of the human multidrug resistance (MDR1) gene
    • Takatori T., Ogura M., Tsuruo T. Purification and characterization of NF-R2 that regulates the expression of the human multidrug resistance (MDR1) gene. Jpn. J. Cancer Res. 84:1993;298-303.
    • (1993) Jpn. J. Cancer Res. , vol.84 , pp. 298-303
    • Takatori, T.1    Ogura, M.2    Tsuruo, T.3
  • 55
    • 0034635186 scopus 로고    scopus 로고
    • Identification and characterization of the MDR1 promoter-enhancing factor 1 (MEF1) in the multidrug resistant HL60/VCR human acute myeloid leukemia cell line
    • Ogretmen B., Safa A.R. Identification and characterization of the MDR1 promoter-enhancing factor 1 (MEF1) in the multidrug resistant HL60/VCR human acute myeloid leukemia cell line. Biochemistry. 39:2000;194-204.
    • (2000) Biochemistry , vol.39 , pp. 194-204
    • Ogretmen, B.1    Safa, A.R.2
  • 56
    • 0033914906 scopus 로고    scopus 로고
    • Modulation of the typical multidrug resistance phenotype by targeting the MED-1 region of human MDR1 promoter
    • Marthinet E., Divita G., Bernaud J., Rigal D., Baggetto L.G. Modulation of the typical multidrug resistance phenotype by targeting the MED-1 region of human MDR1 promoter. Gene Ther. 7:2000;1224-1233.
    • (2000) Gene Ther. , vol.7 , pp. 1224-1233
    • Marthinet, E.1    Divita, G.2    Bernaud, J.3    Rigal, D.4    Baggetto, L.G.5
  • 57
    • 0005123417 scopus 로고    scopus 로고
    • Characterization of a new activating transcriptional element on the human MDR1 gene promoter in multidrug resistant cancer cells
    • Cell signaling, transcription and translation as therapeutic targets, Luxembourg
    • Labialle S, Marthinet E, Gayet L, Rigal D, Baggetto LG. Characterization of a new activating transcriptional element on the human MDR1 gene promoter in multidrug resistant cancer cells. In: Cell signaling, transcription and translation as therapeutic targets. Proceedings of the Third Congress on Signal Transduction, Luxembourg 2002;262.
    • (2002) Proceedings of the Third Congress on Signal Transduction , vol.262
    • Labialle, S.1    Marthinet, E.2    Gayet, L.3    Rigal, D.4    Baggetto, L.G.5
  • 58
    • 0025777044 scopus 로고
    • Functional significance of an overlapping consensus binding motif for Sp1 and Zif268 in the murine adenosine deaminase gene promoter
    • Ackerman S.L., Minden A.G., Williams G.T., Bobonis C., Yeung C.Y. Functional significance of an overlapping consensus binding motif for Sp1 and Zif268 in the murine adenosine deaminase gene promoter. Proc. Natl. Acad. Sci. U.S.A. 88:1991;7523-7527.
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 7523-7527
    • Ackerman, S.L.1    Minden, A.G.2    Williams, G.T.3    Bobonis, C.4    Yeung, C.Y.5
  • 60
    • 0036469065 scopus 로고    scopus 로고
    • Signal transduction and the control of gene expression
    • Brivanlou A.H., Darnell J.E. Jr. Signal transduction and the control of gene expression. Science. 295:2002;813-818.
    • (2002) Science , vol.295 , pp. 813-818
    • Brivanlou, A.H.1    Darnell J.E., Jr.2
  • 61
    • 0033564370 scopus 로고    scopus 로고
    • Association of 5′ CpG demethylation and altered chromatin structure in the promoter region with transcriptional activation of the multidrug resistance 1 gene in human cancer cells
    • Kusaba H., Nakayama M., Harada T., Nomoto M., Kohno K., Kuwano M., Wada M. Association of 5′ CpG demethylation and altered chromatin structure in the promoter region with transcriptional activation of the multidrug resistance 1 gene in human cancer cells. Eur. J. Biochem. 262:1999;924-932.
    • (1999) Eur. J. Biochem. , vol.262 , pp. 924-932
    • Kusaba, H.1    Nakayama, M.2    Harada, T.3    Nomoto, M.4    Kohno, K.5    Kuwano, M.6    Wada, M.7
  • 62
    • 0036182132 scopus 로고    scopus 로고
    • Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation
    • El-Osta A., Kantharidis P., Zalcberg J.R., Wolffe A.P. Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation. Mol. Cell Biol. 22:2002;1844-1857.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 1844-1857
    • El-Osta, A.1    Kantharidis, P.2    Zalcberg, J.R.3    Wolffe, A.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.