Anticancer drug-mediated induction of multidrug resistance-associated genes and protein kinase C isozymes in the T-lymphoblastoid cell line CCRF-CEM and in blasts from patients with acute lymphoblastic leukemias

Japanese Journal of Cancer Research

Volumn 92, Issue 8, 2001, Pages 896-903

  Beck, James F ^a   Brügger, Dorothee ^b   Brischwein, Klaus ^a   Liu, Chao ^b   Bader, Peter ^b   Niethammer, Dietrich ^b   Gekeler, Volker ^c  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c ALTANA PHARMA AG   (Germany)

Author keywords

Acute lymphoblastic leukemia; Anticancer drugs; Gene induction; MDR; Protein kinase C

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; ANTINEOPLASTIC AGENT; BISINDOLYLMALEIMIDE; CAMPTOTHECIN; COMPLEMENTARY DNA; DOXORUBICIN; ETOPOSIDE; ISOENZYME; LUNG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA1; PROTEIN KINASE C BETA2; PROTEIN KINASE C EPSILON; PROTEIN KINASE C ETA; PROTEIN KINASE C IOTA; PROTEIN KINASE C THETA; PROTEIN KINASE C ZETA; PROTEIN KINASE INHIBITOR; STAUROSPORINE; STEROID; UNCLASSIFIED DRUG; VINCRISTINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; BLAST CELL; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER RESISTANCE; CELL LINE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION FUNCTION; DRUG SELECTIVITY; DRUG SPECIFICITY; DRUG TARGETING; ENZYME INDUCTION; GENE EXPRESSION; GENE INDUCTION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LUNG CANCER; MONOTHERAPY; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; T LYMPHOBLAST; TREATMENT FAILURE;

EID: 0034820311     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2001.tb01178.x     Document Type: Article

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