Melatonin prevents the decreased activity of antioxidant enzymes and activates nuclear erythroid 2-related factor 2 signaling in an animal model of fulminant hepatic failure of viral origin

Journal of Pineal Research

Volumn 49, Issue 2, 2010, Pages 193-200

  Crespo, Irene ^a,b   Miguel, Beatriz S ^a,b   Laliena, Almudena ^a   Álvarez, Marcelino ^a   Culebras, Jesús M ^a,b,c   González Gallego, Javier ^a,b   Tuñón, María J ^a,b  

^a UNIVERSITY OF LEÓN   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c Hospital of Leon   (Spain)

Author keywords

antioxidant enzymes; fulminant hepatic failure; melatonin

Indexed keywords

ALANINE AMINOTRANSFERASE; AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; LACTATE DEHYDROGENASE; MANGANESE SUPEROXIDE DISMUTASE; MELATONIN; MESSENGER RNA; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANSCRIPTION FACTOR NRF2;

AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL NUCLEUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVITY; LACTATE DEHYDROGENASE BLOOD LEVEL; LAGOVIRUS; LIVER FAILURE; LIVER LEVEL; LIVER PROTECTION; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RABBIT; SIGNAL TRANSDUCTION; VIRUS ISOLATION;

ANALYSIS OF VARIANCE; ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; CELL NUCLEUS; CYTOSOL; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HEMORRHAGIC DISEASE VIRUS, RABBIT; IMMUNOHISTOCHEMISTRY; LIVER FAILURE, ACUTE; MALE; MELATONIN; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PROTECTIVE AGENTS; RABBITS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE;

EID: 77955123767     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2010.00787.x     Document Type: Article

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