-
1
-
-
0034623211
-
Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor
-
Alam J., Wicks C., Stewart D., Gong P., Touchard C., Otterbein S., Choi A.M., Burow M.E., Tou J. Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor. J. Biol. Chem. 2000, 275:27694-27702.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 27694-27702
-
-
Alam, J.1
Wicks, C.2
Stewart, D.3
Gong, P.4
Touchard, C.5
Otterbein, S.6
Choi, A.M.7
Burow, M.E.8
Tou, J.9
-
2
-
-
0022272493
-
Determination of glutathione and glutathione disulfide in biological samples
-
Anderson M.E. Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol. 1985, 113:548-555.
-
(1985)
Methods Enzymol.
, vol.113
, pp. 548-555
-
-
Anderson, M.E.1
-
3
-
-
33845337024
-
The antioxidant role of a reagent, 2',7'-dichlorodihydrofluorescin diacetate, detecting reactive-oxygen species and blocking the induction of heme oxygenase-1 and preventing cytotoxicity
-
Andoh Y., Mizutani A., Ohashi T., Kojo S., Ishii T., Adachi Y., Ikehara S., Taketani S. The antioxidant role of a reagent, 2',7'-dichlorodihydrofluorescin diacetate, detecting reactive-oxygen species and blocking the induction of heme oxygenase-1 and preventing cytotoxicity. J. Biochem. 2006, 140:483-489.
-
(2006)
J. Biochem.
, vol.140
, pp. 483-489
-
-
Andoh, Y.1
Mizutani, A.2
Ohashi, T.3
Kojo, S.4
Ishii, T.5
Adachi, Y.6
Ikehara, S.7
Taketani, S.8
-
4
-
-
0030451213
-
NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development
-
Chan K., Lu R., Chang J.C., Kan Y.W. NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:13943-13948.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 13943-13948
-
-
Chan, K.1
Lu, R.2
Chang, J.C.3
Kan, Y.W.4
-
5
-
-
70350028746
-
Activation of Nrf2 by cadmium and its role in protection against cadmium-induced apoptosis in rat kidney cells
-
Chen J., Shaikh Z.A. Activation of Nrf2 by cadmium and its role in protection against cadmium-induced apoptosis in rat kidney cells. Toxicol. Appl. Pharmacol. 2009, 241:81-89.
-
(2009)
Toxicol. Appl. Pharmacol.
, vol.241
, pp. 81-89
-
-
Chen, J.1
Shaikh, Z.A.2
-
6
-
-
0027536023
-
Expression, characterization, and tissue distribution of a new cellular selenium-dependent glutathione peroxidase, GSHPx-GI
-
Chu F.F., Doroshow J.H., Esworthy R.S. Expression, characterization, and tissue distribution of a new cellular selenium-dependent glutathione peroxidase, GSHPx-GI. J. Biol. Chem. 1993, 268:2571-2576.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 2571-2576
-
-
Chu, F.F.1
Doroshow, J.H.2
Esworthy, R.S.3
-
7
-
-
4544294365
-
The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase
-
Cullinan S.B., Gordan J.D., Jin J., Harper J.W., Diehl J.A. The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase. Mol. Cell. Biol. 2004, 24:8477-8486.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 8477-8486
-
-
Cullinan, S.B.1
Gordan, J.D.2
Jin, J.3
Harper, J.W.4
Diehl, J.A.5
-
8
-
-
78049467743
-
Autophagy reduces acute ethanol-induced hepatotoxicity and steatosis in mice
-
Ding W.X., Li M., Chen X., Ni H.M., Lin C.W., Gao W., Lu B., Stolz D.B., Clemens D.L., Yin X.M. Autophagy reduces acute ethanol-induced hepatotoxicity and steatosis in mice. Gastroenterology 2010, 139:1740-1752.
-
(2010)
Gastroenterology
, vol.139
, pp. 1740-1752
-
-
Ding, W.X.1
Li, M.2
Chen, X.3
Ni, H.M.4
Lin, C.W.5
Gao, W.6
Lu, B.7
Stolz, D.B.8
Clemens, D.L.9
Yin, X.M.10
-
9
-
-
0020525253
-
Altered subcellular distribution of cadmium following cadmium pretreatment: possible mechanism of tolerance to cadmium-induced lethality
-
Goering P.L., Klaassen C.D. Altered subcellular distribution of cadmium following cadmium pretreatment: possible mechanism of tolerance to cadmium-induced lethality. Toxicol. Appl. Pharmacol. 1983, 70:195-203.
-
(1983)
Toxicol. Appl. Pharmacol.
, vol.70
, pp. 195-203
-
-
Goering, P.L.1
Klaassen, C.D.2
-
10
-
-
0037076920
-
INOS-null mice are not resistant to cadmium chloride-induced hepatotoxicity
-
Harstad E.B., Klaassen C.D. iNOS-null mice are not resistant to cadmium chloride-induced hepatotoxicity. Toxicology 2002, 175:83-90.
-
(2002)
Toxicology
, vol.175
, pp. 83-90
-
-
Harstad, E.B.1
Klaassen, C.D.2
-
11
-
-
0037087569
-
Tumor necrosis factor-alpha-null mice are not resistant to cadmium chloride-induced hepatotoxicity
-
Harstad E.B., Klaassen C.D. Tumor necrosis factor-alpha-null mice are not resistant to cadmium chloride-induced hepatotoxicity. Toxicol. Appl. Pharmacol. 2002, 179:155-162.
-
(2002)
Toxicol. Appl. Pharmacol.
, vol.179
, pp. 155-162
-
-
Harstad, E.B.1
Klaassen, C.D.2
-
12
-
-
0030565592
-
Cadmium-induced production of superoxide anion and nitric oxide, DNA single strand breaks and lactate dehydrogenase leakage in J774A.1 cell cultures
-
Hassoun E.A., Stohs S.J. Cadmium-induced production of superoxide anion and nitric oxide, DNA single strand breaks and lactate dehydrogenase leakage in J774A.1 cell cultures. Toxicology 1996, 112:219-226.
-
(1996)
Toxicology
, vol.112
, pp. 219-226
-
-
Hassoun, E.A.1
Stohs, S.J.2
-
13
-
-
49049106335
-
Activation of Nrf2 in defense against cadmium-induced oxidative stress
-
He X., Chen M.G., Ma Q. Activation of Nrf2 in defense against cadmium-induced oxidative stress. Chem. Res. Toxicol. 2008, 21:1375-1383.
-
(2008)
Chem. Res. Toxicol.
, vol.21
, pp. 1375-1383
-
-
He, X.1
Chen, M.G.2
Ma, Q.3
-
14
-
-
33847050801
-
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
-
Kensler T.W., Wakabayashi N., Biswal S. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu. Rev. Pharmacol. Toxicol. 2007, 47:89-116.
-
(2007)
Annu. Rev. Pharmacol. Toxicol.
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
Wakabayashi, N.2
Biswal, S.3
-
15
-
-
0030848109
-
Role of metallothionein in cadmium-induced hepatotoxicity and nephrotoxicity
-
Klaassen C.D., Liu J. Role of metallothionein in cadmium-induced hepatotoxicity and nephrotoxicity. Drug Metab. Rev. 1997, 29:79-102.
-
(1997)
Drug Metab. Rev.
, vol.29
, pp. 79-102
-
-
Klaassen, C.D.1
Liu, J.2
-
16
-
-
0031966275
-
Induction of metallothionein as an adaptive mechanism affecting the magnitude and progression of toxicological injury
-
Klaassen C.D., Liu J. Induction of metallothionein as an adaptive mechanism affecting the magnitude and progression of toxicological injury. Environ. Health Perspect. 1998, 106(Suppl. 1):297-300.
-
(1998)
Environ. Health Perspect.
, vol.106
, Issue.SUPPL. 1
, pp. 297-300
-
-
Klaassen, C.D.1
Liu, J.2
-
17
-
-
0032953164
-
Metallothionein: an intracellular protein to protect against cadmium toxicity
-
Klaassen C.D., Liu J., Choudhuri S. Metallothionein: an intracellular protein to protect against cadmium toxicity. Annu. Rev. Pharmacol. Toxicol. 1999, 39:267-294.
-
(1999)
Annu. Rev. Pharmacol. Toxicol.
, vol.39
, pp. 267-294
-
-
Klaassen, C.D.1
Liu, J.2
Choudhuri, S.3
-
19
-
-
0026465601
-
Cadmium-induced hepatic endothelial cell injury in inbred strains of mice
-
Liu J., Kershaw W.C., Liu Y.P., Klaassen C.D. Cadmium-induced hepatic endothelial cell injury in inbred strains of mice. Toxicology 1992, 75:51-62.
-
(1992)
Toxicology
, vol.75
, pp. 51-62
-
-
Liu, J.1
Kershaw, W.C.2
Liu, Y.P.3
Klaassen, C.D.4
-
20
-
-
0029595386
-
Transgenic mice that overexpress metallothionein-I are protected from cadmium lethality and hepatotoxicity
-
Liu Y., Liu J., Iszard M.B., Andrews G.K., Palmiter R.D., Klaassen C.D. Transgenic mice that overexpress metallothionein-I are protected from cadmium lethality and hepatotoxicity. Toxicol. Appl. Pharmacol. 1995, 135:222-228.
-
(1995)
Toxicol. Appl. Pharmacol.
, vol.135
, pp. 222-228
-
-
Liu, Y.1
Liu, J.2
Iszard, M.B.3
Andrews, G.K.4
Palmiter, R.D.5
Klaassen, C.D.6
-
21
-
-
0030098629
-
Metallothionein plays less of a protective role in cadmium-metallothionein-induced nephrotoxicity than in cadmium chloride-induced hepatotoxicity
-
Liu J., Liu Y., Michalska A.E., Choo K.H., Klaassen C.D. Metallothionein plays less of a protective role in cadmium-metallothionein-induced nephrotoxicity than in cadmium chloride-induced hepatotoxicity. J. Pharmacol. Exp. Ther. 1996, 276:1216-1223.
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.276
, pp. 1216-1223
-
-
Liu, J.1
Liu, Y.2
Michalska, A.E.3
Choo, K.H.4
Klaassen, C.D.5
-
22
-
-
0035883914
-
Metallothionein-null and wild-type mice show similar cadmium absorption and tissue distribution following oral cadmium administration
-
Liu Y., Liu J., Klaassen C.D. Metallothionein-null and wild-type mice show similar cadmium absorption and tissue distribution following oral cadmium administration. Toxicol. Appl. Pharmacol. 2001, 175:253-259.
-
(2001)
Toxicol. Appl. Pharmacol.
, vol.175
, pp. 253-259
-
-
Liu, Y.1
Liu, J.2
Klaassen, C.D.3
-
23
-
-
0037087238
-
Acute cadmium exposure induces stress-related gene expression in wild-type and metallothionein-I/II-null mice
-
Liu J., Kadiiska M.B., Corton J.C., Qu W., Waalkes M.P., Mason R.P., Liu Y., Klaassen C.D. Acute cadmium exposure induces stress-related gene expression in wild-type and metallothionein-I/II-null mice. Free Radic. Biol. Med. 2002, 32:525-535.
-
(2002)
Free Radic. Biol. Med.
, vol.32
, pp. 525-535
-
-
Liu, J.1
Kadiiska, M.B.2
Corton, J.C.3
Qu, W.4
Waalkes, M.P.5
Mason, R.P.6
Liu, Y.7
Klaassen, C.D.8
-
25
-
-
67649641505
-
Role of oxidative stress in cadmium toxicity and carcinogenesis
-
Liu J., Qu W., Kadiiska M.B. Role of oxidative stress in cadmium toxicity and carcinogenesis. Toxicol. Appl. Pharmacol. 2009, 238:209-214.
-
(2009)
Toxicol. Appl. Pharmacol.
, vol.238
, pp. 209-214
-
-
Liu, J.1
Qu, W.2
Kadiiska, M.B.3
-
26
-
-
79251550085
-
Reduction of cysteine sulfinic acid in eukaryotic, typical 2-Cys peroxiredoxins by sulfiredoxin
-
Lowther W.T., Haynes A.C. Reduction of cysteine sulfinic acid in eukaryotic, typical 2-Cys peroxiredoxins by sulfiredoxin. Antioxid. Redox Signal. 2011, 15:99-109.
-
(2011)
Antioxid. Redox Signal.
, vol.15
, pp. 99-109
-
-
Lowther, W.T.1
Haynes, A.C.2
-
27
-
-
47249160785
-
Glutathione peroxidase family - an evolutionary overview
-
Margis R., Dunand C., Teixeira F.K., Margis-Pinheiro M. Glutathione peroxidase family - an evolutionary overview. FEBS J. 2008, 275:3959-3970.
-
(2008)
FEBS J.
, vol.275
, pp. 3959-3970
-
-
Margis, R.1
Dunand, C.2
Teixeira, F.K.3
Margis-Pinheiro, M.4
-
28
-
-
57349108021
-
Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice
-
Okada K., Shoda J., Taguchi K., Maher J.M., Ishizaki K., Inoue Y., Ohtsuki M., Goto N., Takeda K., Utsunomiya H., Oda K., Warabi E., Ishii T., Osaka K., Hyodo I., Yamamoto M. Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice. Am. J. Physiol. Gastrointest. Liver Physiol. 2008, 295:G735-G747.
-
(2008)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.295
-
-
Okada, K.1
Shoda, J.2
Taguchi, K.3
Maher, J.M.4
Ishizaki, K.5
Inoue, Y.6
Ohtsuki, M.7
Goto, N.8
Takeda, K.9
Utsunomiya, H.10
Oda, K.11
Warabi, E.12
Ishii, T.13
Osaka, K.14
Hyodo, I.15
Yamamoto, M.16
-
29
-
-
79957636715
-
Protective role of diallyl tetrasulfide on cadmium-induced testicular damage in adult rats: a biochemical and histological study
-
Ponnusamy M., Pari L. Protective role of diallyl tetrasulfide on cadmium-induced testicular damage in adult rats: a biochemical and histological study. Toxicol. Ind. Health 2011, 27:407-416.
-
(2011)
Toxicol. Ind. Health
, vol.27
, pp. 407-416
-
-
Ponnusamy, M.1
Pari, L.2
-
30
-
-
77957116879
-
Amelioration of cadmium-induced oxidative stress, impairment in lipids and plasma lipoproteins by the combined treatment with quercetin and alpha-tocopherol in rats
-
Prabu S.M., Shagirtha K., Renugadevi J. Amelioration of cadmium-induced oxidative stress, impairment in lipids and plasma lipoproteins by the combined treatment with quercetin and alpha-tocopherol in rats. J. Food Sci. 2010, 75:T132-T140.
-
(2010)
J. Food Sci.
, vol.75
-
-
Prabu, S.M.1
Shagirtha, K.2
Renugadevi, J.3
-
31
-
-
0033631609
-
Mechanisms of cadmium-mediated acute hepatotoxicity
-
Rikans L.E., Yamano T. Mechanisms of cadmium-mediated acute hepatotoxicity. J. Biochem. Mol. Toxicol. 2000, 14:110-117.
-
(2000)
J. Biochem. Mol. Toxicol.
, vol.14
, pp. 110-117
-
-
Rikans, L.E.1
Yamano, T.2
-
32
-
-
18244386712
-
Transcriptional regulation of thioredoxin reductase 1 expression by cadmium in vascular endothelial cells: role of NF-E2-related factor-2
-
Sakurai A., Nishimoto M., Himeno S., Imura N., Tsujimoto M., Kunimoto M., Hara S. Transcriptional regulation of thioredoxin reductase 1 expression by cadmium in vascular endothelial cells: role of NF-E2-related factor-2. J. Cell. Physiol. 2005, 203:529-537.
-
(2005)
J. Cell. Physiol.
, vol.203
, pp. 529-537
-
-
Sakurai, A.1
Nishimoto, M.2
Himeno, S.3
Imura, N.4
Tsujimoto, M.5
Kunimoto, M.6
Hara, S.7
-
33
-
-
0037462651
-
Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium
-
Stewart D., Killeen E., Naquin R., Alam S., Alam J. Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium. J. Biol. Chem. 2003, 278:2396-2402.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 2396-2402
-
-
Stewart, D.1
Killeen, E.2
Naquin, R.3
Alam, S.4
Alam, J.5
-
34
-
-
1542782410
-
Cadmium induces nuclear export of Bach1, a transcriptional repressor of heme oxygenase-1 gene
-
Suzuki H., Tashiro S., Sun J., Doi H., Satomi S., Igarashi K. Cadmium induces nuclear export of Bach1, a transcriptional repressor of heme oxygenase-1 gene. J. Biol. Chem. 2003, 278:49246-49253.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 49246-49253
-
-
Suzuki, H.1
Tashiro, S.2
Sun, J.3
Doi, H.4
Satomi, S.5
Igarashi, K.6
-
35
-
-
77955577209
-
Transport pathways for cadmium in the intestine and kidney proximal tubule: focus on the interaction with essential metals
-
Vesey D.A. Transport pathways for cadmium in the intestine and kidney proximal tubule: focus on the interaction with essential metals. Toxicol. Lett. 2010, 198:13-19.
-
(2010)
Toxicol. Lett.
, vol.198
, pp. 13-19
-
-
Vesey, D.A.1
-
36
-
-
0345708255
-
Cadmium carcinogenesis
-
Waalkes M.P. Cadmium carcinogenesis. Mutat. Res. 2003, 533:107-120.
-
(2003)
Mutat. Res.
, vol.533
, pp. 107-120
-
-
Waalkes, M.P.1
-
37
-
-
80053452983
-
Beneficial role of Nrf2 in regulating NADPH generation and consumption
-
Wu K.C., Cui J.Y., Klaassen C.D. Beneficial role of Nrf2 in regulating NADPH generation and consumption. Toxicol. Sci. 2011, 123:590-600.
-
(2011)
Toxicol. Sci.
, vol.123
, pp. 590-600
-
-
Wu, K.C.1
Cui, J.Y.2
Klaassen, C.D.3
-
38
-
-
0033978690
-
Attenuation of cadmium-induced liver injury in senescent male Fischer 344 rats: role of Kupffer cells and inflammatory cytokines
-
Yamano T., DeCicco L.A., Rikans L.E. Attenuation of cadmium-induced liver injury in senescent male Fischer 344 rats: role of Kupffer cells and inflammatory cytokines. Toxicol. Appl. Pharmacol. 2000, 162:68-75.
-
(2000)
Toxicol. Appl. Pharmacol.
, vol.162
, pp. 68-75
-
-
Yamano, T.1
DeCicco, L.A.2
Rikans, L.E.3
-
39
-
-
80255126225
-
Induction of glutathione synthesis and heme oxygenase 1 by the flavonoids butein and phloretin is mediated through the ERK/Nrf2 pathway and protects against oxidative stress
-
Yang Y.C., Lii C.K., Lin A.H., Yeh Y.W., Yao H.T., Li C.C., Liu K.L., Chen H.W. Induction of glutathione synthesis and heme oxygenase 1 by the flavonoids butein and phloretin is mediated through the ERK/Nrf2 pathway and protects against oxidative stress. Free Radic. Biol. Med. 2011, 51:2073-2081.
-
(2011)
Free Radic. Biol. Med.
, vol.51
, pp. 2073-2081
-
-
Yang, Y.C.1
Lii, C.K.2
Lin, A.H.3
Yeh, Y.W.4
Yao, H.T.5
Li, C.C.6
Liu, K.L.7
Chen, H.W.8
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