In silico approaches to predict the potential of milk protein-derived peptides as dipeptidyl peptidase IV (DPP-IV) inhibitors

Peptides

Volumn 57, Issue , 2014, Pages 43-51

  Nongonierma, Alice B ^a   Mooney, Catherine ^b   Shields, Denis C ^b   Fitzgerald, Richard J ^a  

^a UNIVERSITY OF LIMERICK   (Ireland)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Bioactive peptides; Dipeptidyl peptidase IV inhibitors; Hydrophobicity; Milk; Molecular docking; Predictive modeling

Indexed keywords

DIPEPTIDYL PEPTIDASE IV INHIBITOR; MILK PROTEIN; DIPEPTIDYL PEPTIDASE IV; PEPTIDE; PROTEIN BINDING;

AMINO ACID SEQUENCE; ARTICLE; COMPETITIVE INHIBITION; COMPUTER MODEL; CONTROLLED STUDY; DRUG BINDING SITE; HYDROGEN BOND; HYDROPHOBICITY; IC 50; IN VITRO STUDY; ISOELECTRIC POINT; MOLECULAR DOCKING; MOLECULAR WEIGHT; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; CHEMICAL PHENOMENA; CHEMISTRY; COMPUTER SIMULATION; ENZYME ACTIVE SITE; HUMAN; METABOLISM;

CATALYTIC DOMAIN; COMPUTER SIMULATION; DIPEPTIDYL PEPTIDASE 4; DIPEPTIDYL-PEPTIDASE IV INHIBITORS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MILK PROTEINS; MOLECULAR DOCKING SIMULATION; PEPTIDES; PROTEIN BINDING;

EID: 84901310564     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2014.04.018     Document Type: Article

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