Acanthoic acid, a diterpene in Acanthopanax koreanum, ameliorates the development of liver fibrosis via LXRs signals

Chemico-Biological Interactions

Volumn 218, Issue , 2014, Pages 63-70

  Bai, Ting ^a   Yao, You Li ^a   Jin, Xue Jun ^a   Lian, Li Hua ^a   Li, Qian ^a   Yang, Ning ^a   Jin, Quan ^a   Wu, Yan Ling ^a   Nan, Ji Xing ^a  

^a YANBIAN UNIVERSITY   (China)

Author keywords

Acanthoic acid (AA); Acanthopanax koreanum Nakai (Araliaceae); Liver fibrosis; Liver X receptors (LXRs)

Indexed keywords

ACANTHOIC ACID; ALANINE AMINOTRANSFERASE; ALPHA SMOOTH MUSCLE ACTIN; ANTIFIBROTIC AGENT; ASPARTATE AMINOTRANSFERASE; COLLAGEN TYPE 1; COLLAGENASE 3; DITERPENE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIVER X RECEPTOR; LIVER X RECEPTOR BETA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACANTHOPANAX KOREANUM; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARALIACEAE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CARBON TETRACHLORIDE-INDUCED LIVER FIBROSIS; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG MEGADOSE; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; PLANT ROOT; RAT; STELLATE CELL;

ACANTHOIC ACID (AA); ACANTHOPANAX KOREANUM NAKAI (ARALIACEAE); CARBON TETRACHLORIDE (CCL(4)); LIVER FIBROSIS; LIVER X RECEPTORS (LXRS);

ACANTHOPANAX; ANIMALS; CARBON TETRACHLORIDE; CELLS, CULTURED; DITERPENES; LIVER CIRRHOSIS; MALE; MICE; MICE, INBRED C57BL; ORPHAN NUCLEAR RECEPTORS; PLANT EXTRACTS; SIGNAL TRANSDUCTION;

EID: 84901250511     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2014.04.016     Document Type: Article

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