Protective effects of silica hydride against carbon tetrachloride-induced hepatotoxicity in mice

Food and Chemical Toxicology

Volumn 48, Issue 6, 2010, Pages 1644-1653

  Hsu, Yu Wen ^a   Tsai, Chia Fang ^a   Chuang, Wen Chen ^b   Chen, Wen Kang ^c   Ho, Yung Chyuan ^a   Lu, Fung Jou ^a,d  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c NATIONAL TAINAN INSTITUTE OF NURSING   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Antioxidant; Carbon tetrachloride; Hepatoprotective effects; Silica hydride

Indexed keywords

CARBON TETRACHLORIDE; CATALASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; LIVER PROTECTIVE AGENT; MALONALDEHYDE; MEGAHYDRATE; SILICA HYDRIDE; SILYMARIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG DOSE COMPARISON; LIPID PEROXIDATION; LIVER FIBROSIS; LIVER INJURY; LIVER NECROSIS; LIVER PROTECTION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; TRIACYLGLYCEROL BLOOD LEVEL;

ALANINE TRANSAMINASE; ALKALINE PHOSPHATASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CARBON TETRACHLORIDE; CHOLESTEROL; DRUG-INDUCED LIVER INJURY; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED ICR; SILICATES; TRIGLYCERIDES;

MUS;

EID: 77952881250     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.03.039     Document Type: Article

References (56)

1. Aruoma O.I. Nutrition and health aspects of free radicals and antioxidants. Food Chem. Toxicol. 1994, 32:671-683.
2. Bansal A.K., Bansal M., Soni G., Bhatnagar D. N-nitrosodiethylamine induced oxidative stress in rat liver. Chem. Biol. Interact. 2005, 156:101-111.
3. Basu S. Carbon tetrachloride-induced lipid peroxidation: eicosanoid formation and their regulation by antioxidant nutrients. Toxicology 2003, 189:113-127.
4. Baudrimont I., Ahouandjivo R., Creppy E.E. Prevention of lipid peroxidation induced by ochratoxin A in Vero cells in culture by several agents. Chem. Biol. Interact. 1997, 104:29-40.
5. Berton T.R., Conti C.J., Mitchell D.L., Aldaz C.M., Lubet R.A., Fischer S.M. The effect of vitamin E acetate on ultravioletinduced mouse skin carcinogenesis. Mol. Carcinog. 1998, 23:175-184.
6. Bhathal P.S., Rose N.R., Mackay I.R., Whittingham S. Strain differences in mice in carbon tetrachloride-induced liver injury. Br. J. Exp. Pathol. 1983, 64:524-533.
7. Brattin W.J., Glende E.A., Recknagel R.O. Pathological mechanisms in carbon tetrachloride hepatotoxicity. J. Free Radic. Biol. Med. 1985, 1:27-38.
8. Campo G.M., Squadrito F., Ceccarelli S., Calo M., Avenoso A., Campo S., Squadrito G., Altavilla D. Reduction of carbon tetrachloride-induced rat liver injury by IRFI 042, a novel dual vitamin E-like antioxidant. Free Radic. Res. 2001, 34:379-393.
9. Cantin A.M., White T.B., Cross C.E., Forman H.J., Sokol R.J., Borowitz D. Antioxidants in cystic fibrosis conclusions from the CF antioxidant workshop, Bethesda, Maryland, November 11-12, 2003. J. Free Radic. Biol. Med. 2007, 42:15-31.
10. Carlise E.M. The nutritional essentiality of silicon. Nutr. Rev. 1982, 40:193-197.
11. Castor J.A., Ferrya G.C., Castro C.R., Sasame S., Fenes O.M., Gilette J.R. Prevention of carbon tetrachloride-induced necrosis by inhibitors of drug metabolism. Further studies on the mechanism of their action. Biochem. Pharmacol. 1974, 23:295-302.
12. 4-induced hepatotoxicity in mice. Food Chem. Toxicol. 2007, 45:456-464.
13. Dambach D.M., Durham S.K., Laskin J.D., Laskin D.L. Distinct roles of NFkappaB p50 in the regulation of acetaminophen-induced inflammatory mediator production and hepatotoxicity. Toxicol. Appl. Pharmacol. 2006, 211:157-165.
14. Esterbauer H. Aldehydic products of lipid peroxidation. Free radicals, Lipid Peroxidation and Cancer 1982, 102-128. Academic Press, New York. D.C.H. McBrien, T.F. Slater (Eds.).
15. 4 does not aggravate liver fibrosis in rats. Food Chem. Toxicol. 2008, 46:2267-2273.
16. Geetha S., Jayamurthy P., Pal K., Pandey S., Kumar R., Sawhney R.C. Hepatoprotective effects of sea buckthorn (Hippophae rhamnoides L.) against carbon tetrachloride induced liver injury in rats. J. Sci. Food Agric 2008, 88:1592-1597.
17. Halliwell B. Antioxidants and human disease: a general introduction. Nutr. Rev. 1997, 55:44-52.
18. Halliwell B., Gutteridge J.M.C. Role of free radicals and catalytic metal irons in human disease: an overview. Meth. Enzymol. 1990, 186:59-85.
19. Hsu Y.W., Tsai C.F., Chang W.H., Ho Y.C., Chen W.K., Lu F.J. Protective effects of Dunaliella salina - a carotenoids-rich alga, against carbon tetrachloride-induced hepatotoxicity in mice. Food Chem. Toxicol. 2008, 46:3311-3317.
20. Hsu Y.W., Tsai C.F., Chen W.K., Lu F.J. Protective effects of seabuckthorn (Hippophae rhamnoides L.) seed oil against carbon tetrachloride-induced hepatotoxicity in mice. Food Chem. Toxicol. 2009, 47:2281-2288.
21. Jung K., Henke W. Developmental changes of antioxidant enzymes activity in kidney and liver from rats. Free Radic. Biol. Med. 1996, 20:613-617.
22. 4 poisoning?. J. Free Radic. Biol. Med. 2000, 28:838-845.
23. Kren V., Walterova D. Silybin and silymarin - new effects and applications. Biomed. Papers 2005, 149:29-41.
24. Lee J.K., Choi C.Y., Chung Y.C., Kim Y.S., Ryu S.Y., Roh S.H., Jeong H.G. Protective effect of saponins derived from roots of Platycodon grandiflorum on tert-butyl hydroperoxide-induced oxidative hepatotoxicity. Toxicol. Lett. 2004, 147:271-282.
25. Lee K.J., Choi J.H., Jeong H.G. Hepatoprotective and antioxidant effects of the coffee diterpenes kahweol and cafestol on carbon tetrachloride-induced liver damage in mice. Food Chem. Toxicol. 2007, 45:2118-2125.
26. Lettéron P., Labbe G., Degott C., Berson A., Fromenty B., Delaforge M., Larrey D., Pessayre D. Mechanism for the protective effects of silymarin against carbon tetrachloride-induced lipid peroxidation and hepatotoxicity in mice. Evidence that silymarin acts both as an inhibitor of metabolic activation and as a chain-breaking antioxidant. Biochem. Pharmcol. 1990, 39:2027-2034.
27. Mansour M.A. Protective effects of thymoquinone and desferrioxamine against hepatotoxicity of carbon tetrachloride in mice. Life Sci. 2000, 66:2583-2591.
28. Marceau P., Biron S., Hould F.S., Marceau S., Simard S., Thung S.N., Kral J.G. Liver pathology and the metabolic syndrome X in severe obesity. J. Clin. Endocrinol. Metab. 1999, 84:1513-1517.
29. + reduced by anionic hydride organosilovane. Sci. Pharm. 2008, 76:241-257.
30. Naik S.R. Antioxidants and their role in biological functions: an overview. Indian Drugs 2003, 40:501-516.
31. Naik S.R., Panda V.S. Antioxidant and hepatoprotective effects of Ginkgo biloba phytosomes in carbon tetrachloride-induced liver injury in rodents. Liver Int. 2007, 27:393-399.
32. Purdy-Lloyd K., Wasmund W., Smith L., Raven P. Clinical effects of a dietary antioxidant silicate supplement, microhydrin, on cardiovascular response to exercise. J. Med. Food 2001, 4:153-161.
33. Recknagel R.O. Carbon tetrachloride hepatotoxicity. Pharmacol. Rev. 1967, 19:145-208.
34. Recknagel R.O., Glende E.A., Dolak J.A., Waller R.L. Mechanisms of carbon tetrachloride toxicity. Pharmacol. Ther. 1989, 43:139-154.
35. Reiter R.J., Tan D., Osuna C., Gitto E. Actions of melatonin in the reduction of oxidative stress. J. Biomed. Sci. 2000, 7:444-458.
36. Rudnicki M., Silveira M.M., Pereira T.V., Oliveira M.R., Reginatto F.H., Dal-Pizzol F., Moreira J.C.F. Protective effects of Passiflora alata extract pretreatment on carbon tetrachloride induced oxidative damage in rats. Food Chem. Toxicol. 2007, 45:656-661.
37. Shaker E., Mahmoud H., Mnaa S. Silymarin, the antioxidant component and Silybum marianum extracts prevent liver damage. Food Chem. Toxicol. 2010, 46:803-806.
38. 4 via inhibition of hepatic stellate cells activation. Food Chem. Toxicol. 2008, 46:3707-3713.
39. Slater T.F., Sawyer B.C. The stimulatory effects of carbon tetrachloride on peroxidative reactions in rat liver fractions in vitro. Inhibitory effects of free-radical scavengers and other agents. Biochem. J. 1971, 123:823-828.
40. Sreelatha S., Padma P.R., Umadevi M. Protective effects of Coriandrum sativum extracts on carbon tetrachloride-induced hepatotoxicity in rats. Food Chem. Toxicol. 2009, 47:702-708.
41. Stephanson C.J., Flanagan G.P. Antioxidant capacity of silica hydride: a combinational photosensitization and fluorescence detection assay. Free Radic. Biol. Med. 2003, 35:1129-1137.
42. Stephanson C.J., Flanagan G.P. Synthesis of a novel anionic hydride organosiloxane presenting biochemical properties. Int. J. Hydrogen Energy 2003, 28:1243-1250.
43. Stephanson C.J., Flanagan G.P. Differential metabolic effects on mitrochondria by silica hydride using capillary electrophoresis. J. Med. Food 2004, 7:79-83.
44. + reduction analyses. Int. J. Hydrogen Energy 2004, 29:459-464.
45. Stephanson C.J., Stephanson A.M., Flanagan G.P. Antioxidant capability and efficacy of Mega-H™ silica hydride, an antioxidant dietary supplement, by in vitro cellular analysis using photosensitization and fluorescence detection. J. Med. Food 2002, 5:9-15.
46. 2+-EDTA-induced 2-hydroxyterephthalate fluorometric analysis. J. Med. Food 2003, 6:249-253.
47. Szymonik-Lesiuk S., Czechowska G., Stryjecka-Zimmer M., Slomka M., Madro A., Celinski K., Wielosz M. Catalase, superoxide dismutase, and glutathione peroxidase activities in various rat tissues after carbon tetrachloride intoxication. J. Hepatobiliary Pancreat. Surg. 2003, 10:309-315.
48. Taira Z., Yabe K., Hamaguchi Y., Hirayama K., Kishimoto M., Ishida S., Ueda Y. Effects of Sho-saiko-to extract and its components, Baicalin, baicalein, glycyrrhizin and glycyrrhetic acid, on pharmacokinetic behavior of salicylamide in carbon tetrachloride intoxicated rats. Food Chem. Toxicol. 2004, 42:803-807.
49. Tsai C.F., Hsu Y.W., Chen W.K., Chang W.H., Yen C.C., Ho Y.C., Lu F.J. Hepatoprotective effect of electrolyzed reduced water against carbon tetrachloride-induced liver damage in mice. Food Chem. Toxicol. 2009, 47:2031-2036.
50. Tsai, C.F., Hsu, Y.W., Chen, W.K., Lu, F.J., Chen, Y.W., Yen, C.C., submitted for publication. 28-Day oral (gavage) toxicity studies of silica hydride in mice. Food Chem. Toxicol.
51. Vaca C.E., Wilhelm J., Harms-Rihsdahl M. Interaction of lipid peroxidation product with DNA. A Rev. Mutat. Res. Rev. Genet. Toxicol. 1988, 195:137-149.
52. Vitaglione P., Morisco F., Caporaso N., Fogliano V. Dietary antioxidant compounds and liver health. Crit. Rev. Food Sci. Nutr. 2004, 44:575-586.
53. 4-induced liver damage. Food Chem. Toxicol. 2004, 42:609-616.
54. Weber L.W.D., Boll M., Stampfl A. Hepatotoxicity and mechanism of action of haloalkanes: carbon tetrachloride as a toxicological model. Crit. Rev. Toxicol. 2003, 33:105-136.
55. Wu J., Danielsson A., Zern M.A. Toxicity of hepatotoxins: new insights into mechanisms and therapy. Expert Opin. Investig. Drugs 1999, 8:585-607.
56. Yang Y.S., Ahn T.H., Lee J.C., Moon C.J., Kim S.H., Jun W., Park S.C., Kim H.C., Kim J.C. Protective effects of Pycnogenol® on carbon tetrachloride-induced hepatotoxicity in Sprague - Dawley rats. Food Chem. Toxicol. 2008, 46:380-387.