A diterpenoid acanthoic acid from Acanthopanax koreanum protects against D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure in mice

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 4, 2008, Pages 738-742

  Nan, Ji Xing ^a   Jin, Xue Jun ^b   Lian, Li Hua ^a   Cai, Xing Fu ^b   Jiang, Ying Zi ^a   Jin, Hong Ri ^b   Lee, Jung Joon ^b  

^a YANBIAN UNIVERSITY   (China)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Acanthoic acid; Acanthopanax koreanum; Apoptosis; Fulminant hepatitis; Tumor necrosis factor

Indexed keywords

ACANTHOIC ACID; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; DITERPENOID; GALACTOSAMINE; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACANTHOPANAX; ACANTHOPANAX KOREANUM; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; CYTOKINE RELEASE; DNA FRAGMENTATION; DRUG MECHANISM; LIVER CELL; LIVER FAILURE; LIVER INJURY; LIVER PROTECTION; MALE; MOUSE; NICK END LABELING; NONHUMAN;

ACANTHOPANAX; ALANINE TRANSAMINASE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPARTATE AMINOTRANSFERASES; DITERPENES; DNA FRAGMENTATION; GALACTOSAMINE; HEPATITIS, TOXIC; IN SITU NICK-END LABELING; LIPOPOLYSACCHARIDES; LIVER FAILURE, ACUTE; MALE; MICE; MICE, INBRED C57BL; PLANT ROOTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 41849111692     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.738     Document Type: Article

References (19)

1. Tiegs G., J. Hepatol., 21, 890-903 (1994).
2. Hase K., Xiong Q., Kadota S., "Studies in Natural Products Chemistry," Vol. 25, ed. by Atta-ur-Rahman, Elsevier Science, Oxford, 2001, pp. 459-482.
3. Lee W. M., N. Engl. J. Med., 329, 1862-1872 (1993).
4. Nakama T., Hirono S., Moriuchi A., Hasuike S., Nagata K., Hori T., Ido A., Hayashi K., Tsubouchi H., Hepatology, 33, 1441-1450 (2001).
5. Galanos C., Freudenberg M. A., Reutte W., Proc. Natl. Acad. Sci. U.S.A., 76, 5939-5943 (1979).
6. Minon A., Rouquet N., Fabre M., Martin S., Pages J. C., Dhainaut J. F., Kahn A., Briand P., Joulin V., Am. J. Respir. Crit. Care Med., 159, 1308-1315 (1999).
7. Tiegs G., Wolter M., Wendel, A., Biochem. Pharmacol., 38, 627-631 (1989).
8. Chosay J. G., Essani N. A., Dunn C. J., Jaeschke H., Am. J. Physiol., 272, G1195-G1200 (1997).
9. Bradham C. A., Plumpe J., Manns M. P., Brenner D. A., Trautwein C., Am. J. Physiol., 275, G387-G392 (1998).
10. Perry L. M., Metzger J., "Medicinal Plants of East and Southeast Asia," MIT Press, Cambridge, MA, 1980, p. 41.
11. Kim Y. H., Chung B. S., Sankawa U., J. Nat. Prod., 51, 1080-1083 (1988).
12. Kang J. S., Linh P. T., Cai X. F., Kim H. S., Lee J. J., Kim Y. H., Arch. Pharm. Res., 24, 407-411 (2001).
13. Kang H. S., Kim Y. H., Lee C. S., Lee J. J., Choi I. P., Pyun K. H., Cell. Immunol., 170, 212-221 (1996).
14. Kang H. S., Song H. K., Lee J. J., Pyun K. H., Choi I., Mediators Inflamm., 7, 257-259 (1998).
15. Kim J. A., Kim D. K., Tae J., Kang O. H., Choi Y. A., Choi S. C., Kim T. H., Nah Y. H., Choi S. J., Kim Y. H., Bae K. H., Lee Y. M., Clin. Chim. Acta, 342, 193-202 (2004).
16. Nan J. X., Park E. J., Nam J. B., Zhao Y. Z., Cai X. F., Kim Y. H., Sohn D. H., Lee J. J., J. Ethnopharmacol., 92, 71-77 (2004).
17. Palladino M. A., Bahjat F. R., Theodorakis E. A., Moldawer L. L., Nat. Rev. Drug Discovery, 2, 736-746 (2003).
18. Chao T.-H., Lam T., Vong B. G., Traves P. G., Hortelano S., Chowdhury C., Bahjat F. R., Lloyd G. K., Moldawer L. L., Bosca L., Palladino M., Theodorakis E. A., ChemBioChem., 6, 133-144 (2005).
19. Saller R., Meier R., Brignoli R., Drugs, 61, 2035-2063 (2001).