Acanthoic acid induces cell apoptosis through activation of the p38 MAPK pathway in HL-60 human promyelocytic leukaemia

Food Chemistry

Volumn 135, Issue 3, 2012, Pages 2112-2117

  Kim, Kil Nam ^a   Ham, Young Min ^b   Moon, Ji Young ^c   Kim, Min Jin ^c   Jung, Yong Hwan ^b   Jeon, You Jin ^d   Lee, Nam Ho ^d   Kang, Nalae ^d   Yang, Hye Mi ^a   Kim, Daekyung ^a   Hyun, Chang Gu ^c  

^a Korea Basic Science Institute (KBSI)   (South Korea)

^b Jeju Biodiversity Research Institute   (South Korea)

^c Jeju Technopark   (South Korea)

^d Jeju National University   (South Korea)

Author keywords

Acanthoic acid (ACAN); Acanthopanax koreanum; Apoptosis; HL 60 cells; Mitogen activated protein kinase (MAPK)

Indexed keywords

ACANTHOIC ACID (ACAN); ACANTHOPANAX KOREANUM; ARALIACEAE; C-JUN N-TERMINAL KINASE; CASPASE-3; CELL APOPTOSIS; CELL VIABILITY; CHEMOPREVENTIVE; EXTRACELLULAR SIGNAL-REGULATED KINASE; HL-60 CELLS; LEUKAEMIA CELLS; MITOGEN ACTIVATED PROTEIN KINASE; MOLECULAR MECHANISM; P38 MAPK; PRE-TREATMENT; SIGNALLING PATHWAYS; THERAPEUTIC POTENTIALS; TIME-DEPENDENT;

CALCIUM ION SENSORS; ENZYME ACTIVITY; PHOSPHORYLATION;

CELL DEATH;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACANTHOIC ACID; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PLANT MEDICINAL PRODUCT; PROTEIN BCL XL; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ACANTHOPANAX KOREANUM; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MEDICINAL PLANT; PROMYELOCYTIC LEUKEMIA; PROTEIN CLEAVAGE;

ACANTHOPANAX; APOPTOSIS; CELL SURVIVAL; DITERPENES; HL-60 CELLS; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MAP KINASE SIGNALING SYSTEM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PLANT EXTRACTS;

ARALIACEAE; ELEUTHEROCOCCUS KOREANUS;

EID: 84865802396     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2012.05.067     Document Type: Article

References (27)

1. N. Ahmad, D.K. Feyes, A.L. Nieminen, R. Agarwal, and H. Mukhtar Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells Journal of the National Cancer Institute 89 24 1997 1881 1886 (Pubitemid 28009824)
2. J. Ahmed-Choudhury, K.T. Williams, L.S. Young, D.H. Adams, and S.C. Afford CD40 mediated human cholangiocyte apoptosis requires JAK2 dependent activation of STAT3 in addition to activation of JNK1/2 and ERK1/2 Cell Signalling 18 4 2006 456 468 (Pubitemid 41790366)
3. S. Boldt, U.H. Weidle, and W. Kolch The role of MAPK pathways in the action of chemotherapeutic drugs Carcinogenesis 23 11 2002 1831 1838 (Pubitemid 35355933)
4. X.F. Cai, G. Shen, N.T. Dat, O.H. Kang, J.A. Kim, Y.M. Lee, J.J. Lee, and Y.H. Kim Inhibitory effect of TNF-alpha and IL-8 secretion by pimarane-type diterpenoids from Acanthopanax koreanum Chemical and Pharmaceutical Bulletin 51 5 2003 605 607 (Pubitemid 41656819)
5. J.D. Cha, M.R. Jeong, H.Y. Kim, J.C. Lee, and K.Y. Lee MAPK activation is necessary to the apoptotic death of KB cells induced by the essential oil isolated from Artemisia iwayomogi Journal of Ethnopharmacology 123 2 2009 308 314
6. G. Chatzinikolaou, D. Nikitovic, A. Berdiaki, A. Zafiropoulos, P. Katonis, N.K. Karamanos, and G.N. Tzanakakis Heparin regulates colon cancer cell growth through p38 mitogen-activated protein kinase signalling Cell Proliferation 43 1 2010 9 18
7. G. Corona, M. Deiana, A. Incani, D. Vauzour, M. Assunta Dessì, and J.P.E. Spencer Inhibition of p38/CREB phosphorylation and COX-2 expression by olive oil polyphenols underlies their anti-proliferative effects Biochemical and Biophysical Research Communications 362 3 2007 606 611 (Pubitemid 47368135)
8. J. Fan, R. Li, R. Zhang, H.L. Liu, N. Zhang, F.Q. Zhang, and K.F. Dou Effect of Bcl-2 and Bax on survival of side population cells from hepatocellular carcinoma cells World Journal of Gastroenterology 13 45 2007 6053 6059 (Pubitemid 350238275)
9. S. Fulda, and K.M. Debatin Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy Oncogene 25 34 2006 4798 4811 (Pubitemid 44187627)
10. M. Gschwind, and G. Huber Apoptotic cell death induced by β-amyloid1-42 peptide is cell type dependent Journal of Neurochemistry 65 1 1995 292 300
11. S.S. Hsu, C.J. Huang, H.H. Cheng, C.T. Chou, H.Y. Lee, J.L. Wang, I.S. Chen, S.I. Liu, Y.C. Lu, H.T. Chang, J.K. Huang, J.S. Chen, and C.R. Jan Anandamide-induced Ca2+ elevation leading to p38 MAPK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells Toxicology 231 1 2007 21 29
12. J.S. Kang, P.T. Linh, X.F. Cai, H.S. Kim, J.J. Lee, and Y.H. Kim Quantitative determination of eleutheroside B and E from Acanthopanax species by high performance liquid chromatography Archives of Pharmacal Research 24 5 2001 407 411 (Pubitemid 33647258)
13. K.N. Kim, S.J. Heo, S.M. Kang, G. Ahn, and Y.J. Jeon Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway Toxicology In Vitro 24 6 2010 1648 1654
14. X. Li, and Z. Darzynkiewicz Cleavage of poly(ADP-ribose) polymerase measured in situ in individual cells: Relationship to DNA fragmentation and cell cycle position during apoptosis Experimental Cell Research 255 1 2000 125 132 (Pubitemid 30115295)
15. G. Lizard, S. Fournel, L. Genestier, N. Dhedin, C. Chaput, M. Flacher, M. Mutin, G. Panaye, and J.P. Revillard Kinetics of plasma membrane and mitochondrial alterations in cells undergoing apoptosis Cytometry 21 3 1995 275 283
16. J.X. Nan, X.J. Jin, L.H. Lian, X.F. Cai, Y.Z. Jiang, H.R. Jin, and J.J. Lee A diterpenoid acanthoic acid from Acanthopanax koreanum protects against d-galactosamine/lipopolysaccharide-induced fulminant hepatic failure in mice Biological and Pharmaceutical Bulletin 31 4 2008 738 742 (Pubitemid 351500495)
17. I. Nicoletti, G. Migliorati, M.C. Pagliacci, F. Grignani, and C. Riccardi A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry Journal of Immunological Methods 139 2 1991 271 279
18. F.J. Oliver, G. de la Rubia, V. Rolli, M.C. Ruiz-Ruiz, G. de Murcia, and J.M. Murcia Importance of poly(ADP-ribose) polymerase and its cleavage in apoptosis. Lesson from an uncleavable mutant The Journal of Biological Chemistry 273 50 1998 33533 33539 (Pubitemid 29005737)
19. N.T. Phuong, K.A. Lee, S.J. Jeong, C.X. Fu, J.K. Choi, Y.H. Kim, and J.S. Kang Capillary electrophoretic method for the determination of diterpenoid isomers in Acanthopanax species Journal of Pharmaceutical and Biomedical Analysis 40 1 2006 56 61 (Pubitemid 43061216)
20. S. Salakou, D. Kardamakis, A.C. Tsamandas, V. Zolota, E. Apostolakis, V. Tzelepi, P. Papathanasopoulos, D.S. Bonikos, T. Papapetropoulos, T. Petsas, and D. Dougenis Increased Bax/Bcl-2 ratio up-regulates caspase-3 and increases apoptosis in the thymus of patients with myasthenia gravis In Vivo 21 1 2007 123 132 (Pubitemid 46359209)
21. K. Shinkai, H. Akedo, M. Mukai, F. Imamura, A. Isoai, M. Kobayashi, and I. Kitagawa Inhibition of in vitro tumor cell invasion by ginsenoside Rg3 Japanese Journal of Cancer Research 87 4 1996 357 362 (Pubitemid 26147848)
22. Y. Sun, and Z.L. Peng Programmed cell death and cancer Postgraduate Medical Journal 85 1001 2009 134 140
23. M.L. Tan, J.P. Ooi, N. Ismail, A.I. Moad, and T.S. Muhammad Programmed cell death pathways and current antitumor targets Pharmaceutical Research 26 7 2009 1547 1560
24. T.H. Ward, J. Cummings, E. Dean, A. Greystoke, J.M. Hou, A. Backen, M. Ranson, and C. Dive Biomarkers of apoptosis British Journal of Cancer 99 6 2008 841 846
25. Y.L. Wu, Y.Z. Jiang, X.J. Jin, L.H. Lian, J.Y. Piao, Y. Wan, H.R. Jin, J. Joon Lee, and J.X. Nan Acanthoic acid, a diterpene in Acanthopanax koreanum, protects acetaminophen-induced hepatic toxicity in mice Phytomedicine: International Journal of Phytotherapy and Phytopharmacology 17 6 2010 475 479
26. E.J. Yang, J.Y. Moon, J.S. Lee, J. Koh, N.H. Lee, and C.G. Hyun Acanthopanax koreanum fruit waste inhibits lipopolysaccharide-induced production of nitric oxide and prostaglandin E2 in RAW 264.7 macrophages Journal of Biomedicine and Biotechnology 2010 2010 715739
27. S.Y. Yang, K.M. Sales, B. Fuller, A.M. Seifalian, and M.C. Winslet Apoptosis and colorectal cancer: Implications for therapy Trends in Molecular Medicine 15 5 2009 225 233