Therapeutic ROS targeting of GADD45γ in the induction of G2/M arrest in primary human colorectal cancer cell lines by cucurbitacin e

Cell Death and Disease

Volumn 5, Issue 4, 2014, Pages

  Hsu, Y C ^a   Huang, T Y ^b   Chen, M J ^c,d  

^a CHANG JUNG CHRISTIAN UNIVERSITY   (Taiwan)

^b TAINAN SIN LAU HOSPITAL   (Taiwan)

^c CHI MEI MEDICAL CENTER   (Taiwan)

^d CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

Colorectal cancer (CRC); Cucurbitacin E; G2 M arrest; Growth arrest and DNA damage 45 (GADD45)

Indexed keywords

ANTINEOPLASTIC AGENT; CELL CYCLE PROTEIN; CELL DIVISION CYCLE PROTEIN 2; CUCURBITACIN E; CYCLIN B1; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45GAMMA; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; CDK1 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE; SIGNAL PEPTIDE; TRITERPENE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL DIVISION; CELL PROLIFERATION; CELL SURVIVAL; COLORECTAL CANCER CELL LINE; COMPLEX FORMATION; DOWN REGULATION; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; METAPHASE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; COLORECTAL TUMOR; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MITOSIS INDEX; NECROSIS; PATHOLOGY; TUMOR CELL LINE; UPREGULATION;

APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; COLORECTAL NEOPLASMS; CYCLIN B1; CYCLIN-DEPENDENT KINASES; DOWN-REGULATION; G2 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOSIS; MITOTIC INDEX; NECROSIS; REACTIVE OXYGEN SPECIES; TRITERPENES; UP-REGULATION;

EID: 84901038224     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.151     Document Type: Article

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