-
1
-
-
0034676455
-
Surfing the p53 network
-
PMID:11099028
-
Vogelstein B, Lane D, Levine AJ. Surfing the p53 network. Nature 2000; 408:307-10; PMID:11099028; http://dx.doi.org/10.1038/35042675.
-
(2000)
Nature
, vol.408
, pp. 307-310
-
-
Vogelstein, B.1
Lane, D.2
Levine, A.J.3
-
2
-
-
78650316134
-
p53 Research: The past thirty years and the next thirty years
-
PMID:20463001
-
Lane D, Levine A. p53 Research: the past thirty years and the next thirty years. Cold Spring Harb Perspect Biol 2010; 2:893; PMID:20463001; http://dx.doi.org/10.1101/cshperspect.a000893.
-
(2010)
Cold Spring Harb Perspect Biol
, vol.2
, pp. 893
-
-
Lane, D.1
Levine, A.2
-
3
-
-
42449114966
-
Transcriptional control of human p53-regulated genes
-
PMID:18431400
-
Riley T, Sontag E, Chen P, Levine A. Transcriptional control of human p53-regulated genes. Nat Rev Mol Cell Biol 2008; 9:402-12; PMID:18431400; http://dx.doi.org/10.1038/nrm2395.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 402-412
-
-
Riley, T.1
Sontag, E.2
Chen, P.3
Levine, A.4
-
4
-
-
0348134742
-
Mono- versus polyubiquitination: Differential control of p53 fate by Mdm2
-
PMID:14671306
-
Li M, Brooks CL, Wu-Baer F, Chen D, Baer R, Gu W. Mono- versus polyubiquitination: differential control of p53 fate by Mdm2. Science 2003; 302:1972-5; PMID:14671306; http://dx.doi.org/10.1126/science.1091362.
-
(2003)
Science
, vol.302
, pp. 1972-1975
-
-
Li, M.1
Brooks, C.L.2
Wu-Baer, F.3
Chen, D.4
Baer, R.5
Gu, W.6
-
5
-
-
31544457877
-
p53 ubiquitination: Mdm2 and beyond
-
PMID:16455486
-
Brooks CL, Gu W. p53 ubiquitination: Mdm2 and beyond. Mol Cell 2006; 21:307-15; PMID:16455486; http://dx.doi.org/10.1016/j.molcel.2006.01.020.
-
(2006)
Mol Cell
, vol.21
, pp. 307-315
-
-
Brooks, C.L.1
Gu, W.2
-
6
-
-
33847276654
-
Monoubiquitylation promotes mitochondrial p53 translocation
-
PMID:17268548
-
Marchenko ND, Wolff S, Erster S, Becker K, Moll UM. Monoubiquitylation promotes mitochondrial p53 translocation. EMBO J 2007; 26:923-34; PMID:17268548; http://dx.doi.org/10.1038/sj.emboj.7601560.
-
(2007)
EMBO J
, vol.26
, pp. 923-934
-
-
Marchenko, N.D.1
Wolff, S.2
Erster, S.3
Becker, K.4
Moll, U.M.5
-
7
-
-
79959217794
-
UBE4B, a ubiquitin chain assembly factor, is required for MDM2-mediated p53 polyubiquitination and degradation
-
PMID:21558803
-
Wu H, Leng RP. UBE4B, a ubiquitin chain assembly factor, is required for MDM2-mediated p53 polyubiquitination and degradation. Cell Cycle 2011; 10:1912-5; PMID:21558803; http://dx.doi.org/10.4161/cc.10.12.15882.
-
(2011)
Cell Cycle
, vol.10
, pp. 1912-1915
-
-
Wu, H.1
Leng, R.P.2
-
8
-
-
79952677705
-
p21(WAF1) is component of a positive feedback loop that maintains the p53 transcriptional program
-
PMID:21368573
-
Pang LY, Scott M, Hayward RL, Mohammed H, Whitelaw CB, Smith GC, et al. p21(WAF1) is component of a positive feedback loop that maintains the p53 transcriptional program. Cell Cycle 2011; 10:932-50; PMID:21368573; http://dx.doi.org/10.4161/cc.10.6.15012.
-
(2011)
Cell Cycle
, vol.10
, pp. 932-950
-
-
Pang, L.Y.1
Scott, M.2
Hayward, R.L.3
Mohammed, H.4
Whitelaw, C.B.5
Smith, G.C.6
-
9
-
-
77958501169
-
Depletion of ribosomal protein L37 occurs in response to DNA damage and activates p53 through the L11/MDM2 pathway
-
PMID:20935493
-
Llanos S, Serrano M. Depletion of ribosomal protein L37 occurs in response to DNA damage and activates p53 through the L11/MDM2 pathway. Cell Cycle 2010; 9:4005-12; PMID:20935493; http://dx.doi.org/10.4161/cc.9.19.13299.
-
(2010)
Cell Cycle
, vol.9
, pp. 4005-4012
-
-
Llanos, S.1
Serrano, M.2
-
10
-
-
80052063360
-
The RP-Mdm2-p53 pathway and tumorigenesis
-
PMID:21406728
-
Miliani de Marval PL, Zhang Y. The RP-Mdm2-p53 pathway and tumorigenesis. Oncotarget 2011; 2:234-8; PMID:21406728.
-
(2011)
Oncotarget
, vol.2
, pp. 234-238
-
-
Miliani De Marval, P.L.1
Zhang, Y.2
-
11
-
-
77955740487
-
Nucleostemin: Another nucleolar "Twister" of the p53-MDM2 loop
-
PMID:20703089
-
Lo D, Lu H. Nucleostemin: Another nucleolar "Twister" of the p53-MDM2 loop. Cell Cycle 2010; 9:3227-32; PMID:20703089; http://dx.doi.org/10. 4161/cc.9.16.12605.
-
(2010)
Cell Cycle
, vol.9
, pp. 3227-3232
-
-
Lo, D.1
Lu, H.2
-
12
-
-
79958010386
-
Novel insights into the molecular mechanisms governing Mdm2 ubiquitination and destruction
-
PMID:21317463
-
Inuzuka H, Fukushima H, Shaik S, Wei W. Novel insights into the molecular mechanisms governing Mdm2 ubiquitination and destruction. Oncotarget 2010; 1:685-90; PMID:21317463.
-
(2010)
Oncotarget
, vol.1
, pp. 685-690
-
-
Inuzuka, H.1
Fukushima, H.2
Shaik, S.3
Wei, W.4
-
13
-
-
33750834640
-
E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation
-
PMID:17110336
-
Le Cam L, Linares LK, Paul C, Julien E, Lacroix M, Hatchi E, et al. E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation. Cell 2006; 127:775-88; PMID:17110336; http://dx.doi.org/10.1016/j.cell.2006.09.031.
-
(2006)
Cell
, vol.127
, pp. 775-788
-
-
Le Cam, L.1
Linares, L.K.2
Paul, C.3
Julien, E.4
Lacroix, M.5
Hatchi, E.6
-
14
-
-
0033570892
-
Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1
-
PMID:10562558
-
Gostissa M, Hengstermann A, Fogal V, Sandy P, Schwarz SE, Scheffner M, et al. Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1. EMBO J 1999; 18:6462-71; PMID:10562558; http://dx.doi.org/10.1093/emboj/18.22.6462.
-
(1999)
EMBO J
, vol.18
, pp. 6462-6471
-
-
Gostissa, M.1
Hengstermann, A.2
Fogal, V.3
Sandy, P.4
Schwarz, S.E.5
Scheffner, M.6
-
15
-
-
33748528094
-
Ubiquitin and ubiquitinlike modifications of the p53 family
-
PMID:16925948
-
Watson IR, Irwin MS. Ubiquitin and ubiquitinlike modifications of the p53 family. Neoplasia 2006; 8:655-66; PMID:16925948; http://dx.doi.org/10.1593/neo. 06439.
-
(2006)
Neoplasia
, vol.8
, pp. 655-666
-
-
Watson, I.R.1
Irwin, M.S.2
-
16
-
-
24144483441
-
Topors acts as a SUMO-1 E3 ligase for p53 in vitro and in vivo
-
PMID:16122737
-
Weger S, Hammer E, Heilbronn R. Topors acts as a SUMO-1 E3 ligase for p53 in vitro and in vivo. FEBS Lett 2005; 579:5007-12; PMID:16122737; http://dx.doi.org/10.1016/j.febslet.2005.07.088.
-
(2005)
FEBS Lett
, vol.579
, pp. 5007-5012
-
-
Weger, S.1
Hammer, E.2
Heilbronn, R.3
-
17
-
-
33745210316
-
The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis
-
PMID:16793547
-
Bischof O, Schwamborn K, Martin N, Werner A, Sustmann C, Grosschedl R, et al. The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis. Mol Cell 2006; 22:783-94; PMID:16793547; http://dx.doi.org/10.1016/j. molcel.2006.05.016.
-
(2006)
Mol Cell
, vol.22
, pp. 783-794
-
-
Bischof, O.1
Schwamborn, K.2
Martin, N.3
Werner, A.4
Sustmann, C.5
Grosschedl, R.6
-
18
-
-
79952281303
-
SUMO E3 ligase activity of TRIM proteins
-
PMID:20972456
-
Chu Y, Yang X. SUMO E3 ligase activity of TRIM proteins. Oncogene 2011; 30:1108-16; PMID:20972456; http://dx.doi.org/10.1038/onc.2010.462.
-
(2011)
Oncogene
, vol.30
, pp. 1108-1116
-
-
Chu, Y.1
Yang, X.2
-
19
-
-
80052899294
-
MDM2 promotes SUMO-2/3 modification of p53 to modulate transcriptional activity
-
PMID:21900752
-
Stindt MH, Carter S, Vigneron AM, Ryan KM, Vousden KH. MDM2 promotes SUMO-2/3 modification of p53 to modulate transcriptional activity. Cell Cycle 2011; 10:3176-88; PMID:21900752; http://dx.doi.org/10.4161/cc.10.18.17436.
-
(2011)
Cell Cycle
, vol.10
, pp. 3176-3188
-
-
Stindt, M.H.1
Carter, S.2
Vigneron, A.M.3
Ryan, K.M.4
Vousden, K.H.5
-
20
-
-
3142611072
-
Neddylating the guardian; Mdm2 catalyzed conjugation of Nedd8 to p53
-
PMID:15242638
-
Harper JW. Neddylating the guardian; Mdm2 catalyzed conjugation of Nedd8 to p53. Cell 2004; 118:2-4; PMID:15242638; http://dx.doi.org/10.1016/j.cell. 2004.06.015.
-
(2004)
Cell
, vol.118
, pp. 2-4
-
-
Harper, J.W.1
-
21
-
-
30444452500
-
TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases
-
PMID:16237670
-
Meroni G, Diez-Roux G. TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases. Bioessays 2005; 27:1147-57; PMID:16237670; http://dx.doi.org/10.1002/bies.20304.
-
(2005)
Bioessays
, vol.27
, pp. 1147-1157
-
-
Meroni, G.1
Diez-Roux, G.2
-
22
-
-
17744371839
-
The tripartite motif family identifies cell compartments
-
PMID:11331580
-
Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, et al. The tripartite motif family identifies cell compartments. EMBO J 2001; 20:2140-51; PMID:11331580; http://dx.doi.org/10.1093/emboj/20.9.2140.
-
(2001)
EMBO J
, vol.20
, pp. 2140-2151
-
-
Reymond, A.1
Meroni, G.2
Fantozzi, A.3
Merla, G.4
Cairo, S.5
Luzi, L.6
-
23
-
-
0033918327
-
Gene encoding a new RING-B-box-Coiled-coil protein is mutated in mulibrey nanism
-
PMID:10888877
-
Avela K, Lipsanen-Nyman M, Idänheimo N, SeemanováE, Rosengren S, Mäkelä TP, et al. Gene encoding a new RING-B-box-Coiled-coil protein is mutated in mulibrey nanism. Nat Genet 2000; 25:298-301; PMID:10888877; http://dx.doi.org/10.1038/77053.
-
(2000)
Nat Genet
, vol.25
, pp. 298-301
-
-
Avela, K.1
Lipsanen-Nyman, M.2
Idänheimo, N.3
Seemanová, E.4
Rosengren, S.5
Mäkelä, T.P.6
-
24
-
-
0036179479
-
Limb-girdle muscular dystrophy type 2H associated with mutation in TRIM32, a putative E3-ubiquitin-ligase gene
-
PMID:11822024
-
Frosk P, Weiler T, Nylen E, Sudha T, Greenberg CR, Morgan K, et al. Limb-girdle muscular dystrophy type 2H associated with mutation in TRIM32, a putative E3-ubiquitin-ligase gene. Am J Hum Genet 2002; 70:663-72; PMID:11822024; http://dx.doi.org/10.1086/339083.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 663-672
-
-
Frosk, P.1
Weiler, T.2
Nylen, E.3
Sudha, T.4
Greenberg, C.R.5
Morgan, K.6
-
25
-
-
50149085519
-
Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase
-
PMID:18398435
-
Micale L, Fusco C, Augello B, Napolitano LM, Dermitzakis ET, Meroni G, et al. Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase. Eur J Hum Genet 2008; 16:1038-49; PMID:18398435; http://dx.doi.org/10.1038/ejhg.2008.68.
-
(2008)
Eur J Hum Genet
, vol.16
, pp. 1038-1049
-
-
Micale, L.1
Fusco, C.2
Augello, B.3
Napolitano, L.M.4
Dermitzakis, E.T.5
Meroni, G.6
-
26
-
-
16944365777
-
Opitz G/BBB syndrome, a defect of midline development, is due to mutations in a new RING finger gene on Xp22
-
PMID:9354791
-
Quaderi NA, Schweiger S, Gaudenz K, Franco B, Rugarli EI, Berger W, et al. Opitz G/BBB syndrome, a defect of midline development, is due to mutations in a new RING finger gene on Xp22. Nat Genet 1997; 17:285-91; PMID:9354791; http://dx.doi.org/10.1038/ng1197-285.
-
(1997)
Nat Genet
, vol.17
, pp. 285-291
-
-
Quaderi, N.A.1
Schweiger, S.2
Gaudenz, K.3
Franco, B.4
Rugarli, E.I.5
Berger, W.6
-
27
-
-
1542288934
-
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys
-
PMID:14985764
-
Stremlau M, Owens CM, Perron MJ, Kiessling M, Autissier P, Sodroski J. The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature 2004; 427:848-53; PMID:14985764; http://dx.doi.org/10.1038/ nature02343.
-
(2004)
Nature
, vol.427
, pp. 848-853
-
-
Stremlau, M.1
Owens, C.M.2
Perron, M.J.3
Kiessling, M.4
Autissier, P.5
Sodroski, J.6
-
28
-
-
34548858427
-
Molecular classification of nodal metastasis in primary larynx squamous cell carcinoma
-
PMID:17900511
-
Carinci F, Arcelli D, Lo Muzio L, Francioso F, Valentini D, Evangelisti R, et al. Molecular classification of nodal metastasis in primary larynx squamous cell carcinoma. Transl Res 2007; 150:233-45; PMID:17900511; http://dx.doi.org/10.1016/j.trsl.2007.03.011.
-
(2007)
Transl Res
, vol.150
, pp. 233-245
-
-
Carinci, F.1
Arcelli, D.2
Lo Muzio, L.3
Francioso, F.4
Valentini, D.5
Evangelisti, R.6
-
29
-
-
0033118933
-
DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization
-
PMID:10202145
-
Shieh SY, Taya Y, Prives C. DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization. EMBO J 1999; 18:1815-23; PMID:10202145; http://dx.doi.org/10.1093/emboj/18.7. 1815.
-
(1999)
EMBO J
, vol.18
, pp. 1815-1823
-
-
Shieh, S.Y.1
Taya, Y.2
Prives, C.3
-
30
-
-
0141733164
-
Phosphorylation site interdependence of human p53 post-translational modifications in response to stress
-
PMID:12860987
-
Saito S, Yamaguchi H, Higashimoto Y, Chao C, Xu Y, Fornace AJ Jr, et al. Phosphorylation site interdependence of human p53 post-translational modifications in response to stress. J Biol Chem 2003; 278:37536-44; PMID:12860987; http://dx.doi.org/10.1074/jbc.M305135200.
-
(2003)
J Biol Chem
, vol.278
, pp. 37536-37544
-
-
Saito, S.1
Yamaguchi, H.2
Higashimoto, Y.3
Chao, C.4
Xu, Y.5
Fornace Jr., A.J.6
-
31
-
-
33845433364
-
Ser46 phosphorylation regulates p53-dependent apoptosis and replicative senescence
-
PMID:17172844
-
Feng L, Hollstein M, Xu Y. Ser46 phosphorylation regulates p53-dependent apoptosis and replicative senescence. Cell Cycle 2006; 5:2812-9; PMID:17172844; http://dx.doi.org/10.4161/cc.5.23.3526.
-
(2006)
Cell Cycle
, vol.5
, pp. 2812-2819
-
-
Feng, L.1
Hollstein, M.2
Xu, Y.3
-
32
-
-
34248231113
-
p53FamTaG: A database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray data
-
PMID:17430565
-
Sbisà E, Catalano D, Grillo G, Licciulli F, Turi A, Liuni S, et al. p53FamTaG: a database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray data. BMC Bioinformatics 2007; 8:20; PMID:17430565; http://dx.doi.org/10.1186/1471-2105-8-S1-S20.
-
(2007)
BMC Bioinformatics
, vol.8
, pp. 20
-
-
Sbisà, E.1
Catalano, D.2
Grillo, G.3
Licciulli, F.4
Turi, A.5
Liuni, S.6
-
33
-
-
82755190610
-
Tripartite motif 8 (TRIM8) modulates TNFα- And IL-1β-triggered NFκB activation by targeting TAK1 for K63-linked polyubiquitination
-
PMID:22084099
-
Li Q, Yan J, Mao AP, Li C, Ran Y, Shu HB, et al. Tripartite motif 8 (TRIM8) modulates TNFα- and IL-1β-triggered NFκB activation by targeting TAK1 for K63-linked polyubiquitination. Proc Natl Acad Sci USA 2011; 108:19341-6; PMID:22084099; http://dx.doi.org/10.1073/pnas.1110946108.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 19341-19346
-
-
Li, Q.1
Yan, J.2
Mao, A.P.3
Li, C.4
Ran, Y.5
Shu, H.B.6
-
34
-
-
67650895889
-
Trim24 targets endogenous p53 for degradation
-
PMID:19556538
-
Allton K, Jain AK, Herz HM, Tsai WW, Jung SY, Qin J, et al. Trim24 targets endogenous p53 for degradation. Proc Natl Acad Sci USA 2009; 106:11612-6; PMID:19556538; http://dx.doi.org/10.1073/pnas.0813177106.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 11612-11616
-
-
Allton, K.1
Jain, A.K.2
Herz, H.M.3
Tsai, W.W.4
Jung, S.Y.5
Qin, J.6
-
35
-
-
70449758781
-
Regulation of p53: TRIM24 enters the RING
-
PMID:19844164
-
Jain AK, Barton MC. Regulation of p53: TRIM24 enters the RING. Cell Cycle 2009; 8:3668-74; PMID:19844164; http://dx.doi.org/10.4161/cc.8.22.9979.
-
(2009)
Cell Cycle
, vol.8
, pp. 3668-3674
-
-
Jain, A.K.1
Barton, M.C.2
-
36
-
-
45949110751
-
PML enhances the regulation of p53 by CK1 in response to DNA damage
-
PMID:18246126
-
Alsheich-Bartok O, Haupt S, Alkalay-Snir I, Saito S, Appella E, Haupt Y. PML enhances the regulation of p53 by CK1 in response to DNA damage. Oncogene 2008; 27:3653-61; PMID:18246126; http://dx.doi.org/10.1038/sj.onc.1211036.
-
(2008)
Oncogene
, vol.27
, pp. 3653-3661
-
-
Alsheich-Bartok, O.1
Haupt, S.2
Alkalay-Snir, I.3
Saito, S.4
Appella, E.5
Haupt, Y.6
-
37
-
-
77953416244
-
The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions
-
PMID:20368352
-
Yuan Z, Villagra A, Peng L, Coppola D, Glozak M, Sotomayor EM, et al. The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions. Mol Cell Biol 2010; 30:3004-15; PMID:20368352; http://dx.doi.org/10.1128/MCB.01023- 09.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 3004-3015
-
-
Yuan, Z.1
Villagra, A.2
Peng, L.3
Coppola, D.4
Glozak, M.5
Sotomayor, E.M.6
-
38
-
-
72249108928
-
p73 and p63 sustain cellular growth by transcriptional activation of cell cycle progression genes
-
PMID:19861536
-
Lefkimmiatis K, Caratozzolo MF, Merlo P, D'Erchia AM, Navarro B, Levrero M, et al. p73 and p63 sustain cellular growth by transcriptional activation of cell cycle progression genes. Cancer Res 2009; 69:8563-71; PMID:19861536; http://dx.doi.org/10.1158/0008-5472.CAN-09-0259.
-
(2009)
Cancer Res
, vol.69
, pp. 8563-8571
-
-
Lefkimmiatis, K.1
Caratozzolo, M.F.2
Merlo, P.3
D'Erchia, A.M.4
Navarro, B.5
Levrero, M.6
-
39
-
-
31144431726
-
Connecting p63 to cellular proliferation: The example of the adenosine deaminase target gene
-
PMID:16410722
-
Sbisà E, Mastropasqua G, Lefkimmiatis K, Caratozzolo MF, D'Erchia AM, Tullo A. Connecting p63 to cellular proliferation: the example of the adenosine deaminase target gene. Cell Cycle 2006; 5:205-12; PMID:16410722; http://dx.doi.org/10.4161/cc.5.2.2361.
-
(2006)
Cell Cycle
, vol.5
, pp. 205-212
-
-
Sbisà, E.1
Mastropasqua, G.2
Lefkimmiatis, K.3
Caratozzolo, M.F.4
D'Erchia, A.M.5
Tullo, A.6
|