Cucurbitacin B induces cell cycle arrest, apoptosis and autophagy associated with G actin reduction and persistent activation of cofilin in Jurkat cells

Pharmacology

Volumn 89, Issue 5-6, 2012, Pages 348-356

  Zhu, Jun Shan ^a   Ouyang, Dong Yun ^a   Shi, Zhi Jian ^a   Xu, Li Hui ^a   Zhang, Yan Ting ^a   He, Xian Hui ^a  

^a JINAN UNIVERSITY   (China)

Author keywords

Actin dynamics; Apoptosis; Autophagy; Cell cycle arrest; Cucurbitacin B; Jurkat cells

Indexed keywords

CASPASE 3; COFILIN; CUCURBITACIN; CUCURBITACIN B; G ACTIN; LIPOCORTIN 5; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL CYCLE ARREST; CELL PROLIFERATION; DEPHOSPHORYLATION; DRUG MECHANISM; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; M PHASE CELL CYCLE CHECKPOINT; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; T CELL LEUKEMIA; TETRAPLOIDY;

ACTIN DEPOLYMERIZING FACTORS; ACTINS; ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; CASPASE 3; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; HUMANS; JURKAT CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; TRITERPENES;

EID: 84862180365     PISSN: 00317012     EISSN: 14230313     Source Type: Journal    
DOI: 10.1159/000338757     Document Type: Article

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