Transition metal-free cascade reactions of alkynols to afford isoquinolin-1(2H)-one and dihydroisobenzofuran derivatives

Journal of Organic Chemistry

Volumn 79, Issue 10, 2014, Pages 4602-4614

  Li, Deng Yuan ^a   Shi, Ke Ji ^a   Mao, Xiao Feng ^a   Chen, Guo Rong ^a   Liu, Pei Nian ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMISTRY; ORGANIC COMPOUNDS;

ALKYNOLS; CASCADE REACTIONS; MULTI-COMPONENT REACTIONS; NATURAL PRODUCTS; POTASSIUM TERT-BUTOXIDE; REACTION SOLVENTS; TWO-STEP PROCEDURE;

TRANSITION METALS;

2 (3,5 DIMETHYLPHENYL) 3 PHENYLISOQUINOLIN 1(2H) ONE; 2 (4 METHOXYPHENYL) 3 PHENYLISOQUINOLIN 1(2H) ONE; 2 CYCLOHEXYL 3 PHENYLISOQUINOLIN 1(2H) ONE; 2 METHYL 3 PHENYLISOQUINOLIN 1(2H) ONE; 2 PHENYL 3 (3,4,5 TRIMETHOXYPHENYL)ISOQUINOLIN 1(2H) ONE; 2 PHENYL 3 (P TOLYL)ISOQUINOLIN 1(2H) ONE; 2 PHENYL 3 (PYRIDIN 4 YL)ISOQUINOLIN 1(2H) ONE; 2 PHENYL 3 [4 (PIPERIDIN 1 YL)PHENYL]ISOQUINOLIN 1(2H) ONE; 2,3 DIPHENYLISOQUINOLIN 1(2H) ONE; 3 (3,4 DIMETHOXYPHENYL) 2 PHENYLISOQUINOLIN 1(2H) ONE; 3 (4 BROMOPHENYL) 2 PHENYLISOQUINOLIN 1(2H) ONE; 3 (4 METHOXYPHENYL) 2 PHENYLISOQUINOLIN 1(2H) ONE; 3 (4 METHOXYPHENYL) 2,4 DIPHENYLISOQUINOLIN 1(2H) ONE; 3 (4 METHOXYPHENYL) 4 METHYL 2 PHENYLISOQUINOLIN 1(2H) ONE; 3 (4 METHOXYPHENYL) 6 METHYL 2 PHENYLISOQUINOLIN 1(2H) ONE; 3 (4 MORPHOLINOPHENYL) 2 PHENYLISOQUINOLIN 1(2H) ONE; 3 (NAPHTHALEN 2 YL) 2 PHENYLISOQUINOLIN 1(2H) ONE; 3 PHENYL 2 (P TOLYL)ISOQUINOLIN 1(2H) ONE; 3 PHENYL 2 PROPYLISOQUINOLIN 1(2H) ONE; 3 [4 (METHYLTHIO)PHENYL] 2 PHENYLISOQUINOLIN 1(2 H) ONE; 5H ISOQUINOLINO[3,2 A]ISOQUINOLIN 8(6H) ONE; 6 CHLORO 3 (4 METHOXYPHENYL) 2 PHENYLISOQUINOLIN 1(2H) ONE; 6 FLUORO 3 (4 METHOXYPHENYL) 2 PHENYLISOQUINOLIN 1(2H) ONE; 6,7 DIMETHOXY 3 (4 METHOXYPHENYL) 2 PHENYLISOQUINOLIN 1(2H) ONE; 7 (4 METHOXYPHENYL) 6 PHENYL [1,3]DIOXOLO[4,5 G]ISOQUINOLIN 5(6H) ONE; 7 METHOXY 3 (4 METHOXYPHENYL) 2 PHENYLISOQUINOLIN 1(2H) ONE; ISOBENZOFURAN DERIVATIVE; ISOQUINOLINE DERIVATIVE; TRANSITION ELEMENT; UNCLASSIFIED DRUG; UNINDEXED DRUG; 8-OXYPSEUDOPALMATINE; ALDEHYDE; AMINE; BENZOFURAN DERIVATIVE; BERBERINE DERIVATIVE;

ARTICLE; CATALYSIS; CATALYST; COLUMN CHROMATOGRAPHY; CYCLIZATION; DRUG SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; SYNTHESIS;

ALDEHYDES; AMINES; BENZOFURANS; BERBERINE ALKALOIDS; CATALYSIS; ISOQUINOLINES; MOLECULAR STRUCTURE; TRANSITION ELEMENTS;

EID: 84900844474     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo5006312     Document Type: Article

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