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Volumn 306, Issue 4, 2014, Pages 313-330

NADPH oxidase enzymes in skin fibrosis: Molecular targets and therapeutic agents

Author keywords

NADPH oxidase; Nox; Reactive oxygen species; ROS; Skin fibrosis; Transforming growth factor beta

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; BLEOMYCIN; CYTOKINE; DOCETAXEL; EBSELEN; ENZYME INHIBITOR; GKT 137831; GP91DSTAT; GROWTH FACTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; M 090; ML 171; NORPHENAZONE; NOX INHIBITOR; PACLITAXEL; PENTOXIFYLLINE; PEPTIDE; PR 39; PRAVASTATIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RESVERATROL; S 17834; TAXANE DERIVATIVE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UNINDEXED DRUG; VAS 2870; GKT137831; NEUTROPHIL CYTOSOLIC FACTOR 1; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE;

EID: 84900809399     PISSN: 03403696     EISSN: 1432069X     Source Type: Journal    
DOI: 10.1007/s00403-013-1416-8     Document Type: Review
Times cited : (42)

References (127)
  • 2
    • 33751562718 scopus 로고    scopus 로고
    • Increased expression of gp91phox homologues of NAD(P)H oxidase in the aortic media during chronic hypertension: Involvement of the renin-angiotensin system
    • doi:10. 1291/hypres.29.813
    • Akasaki T, Ohya Y, Kuroda J, Eto K, Abe I, Sumimoto H, Iida M (2006) Increased expression of gp91phox homologues of NAD(P)H oxidase in the aortic media during chronic hypertension: involvement of the renin-angiotensin system. Hypertens Res Off J Japanese Soc Hypertens 29(10):813-820. doi:10. 1291/hypres.29.813
    • (2006) Hypertens Res off J Japanese Soc Hypertens , vol.29 , Issue.10 , pp. 813-820
    • Akasaki, T.1    Ohya, Y.2    Kuroda, J.3    Eto, K.4    Abe, I.5    Sumimoto, H.6    Iida, M.7
  • 3
    • 34248582844 scopus 로고    scopus 로고
    • Novel action of paclitaxel against cancer cells: Bystander effect mediated by reactive oxygen species
    • DOI 10.1158/0008-5472.CAN-06-3914
    • Alexandre J, Hu Y, Lu W, Pelicano H, Huang P (2007) Novel action of paclitaxel against cancer cells: bystander effect mediated by reactive oxygen species. Cancer Res 67(8):3512-3517. doi:10.1158/0008-5472.CAN-06-3914 (Pubitemid 46762129)
    • (2007) Cancer Research , vol.67 , Issue.8 , pp. 3512-3517
    • Alexandre, J.1    Hu, Y.2    Lu, W.3    Pelicano, H.4    Huang, P.5
  • 8
    • 24144432258 scopus 로고    scopus 로고
    • Liver fibrogenesis: A new role for the renin-angiotensin system
    • DOI 10.1089/ars.2005.7.1346
    • Bataller R, Sancho-Bru P, Gines P, Brenner DA (2005) Liver fibrogenesis: a new role for the renin-angiotensin system. Antioxid Redox Signal 7(9-10):1346-1355. doi:10.1089/ars.2005.7.1346 (Pubitemid 41232532)
    • (2005) Antioxidants and Redox Signaling , vol.7 , Issue.9-10 , pp. 1346-1355
    • Bataller, R.1    Sancho-Bru, P.2    Gines, P.3    Brenner, D.A.4
  • 10
    • 82955219594 scopus 로고    scopus 로고
    • New insights on chemically induced animal models of systemic sclerosis
    • doi:10.1097/BOR.0b013e32834b1606
    • Batteux F, Kavian N, Servettaz A (2011) New insights on chemically induced animal models of systemic sclerosis. Curr Opin Rheumatol 23(6):511-518. doi:10.1097/BOR.0b013e32834b1606
    • (2011) Curr Opin Rheumatol , vol.23 , Issue.6 , pp. 511-518
    • Batteux, F.1    Kavian, N.2    Servettaz, A.3
  • 11
    • 0025039574 scopus 로고
    • Pentoxifylline inhibits the proliferation of human fibroblasts derived from keloid, scleroderma and morphoea skin and their production of collagen, glycosaminoglycans and fibronectin
    • DOI 10.1111/j.1365-2133.1990.tb06294.x
    • Berman B, Duncan MR (1990) Pentoxifylline inhibits the proliferation of human fibroblasts derived from keloid, scleroderma and morphoea skin and their production of collagen, glycosaminoglycans and fibronectin. Br J Dermatol 123(3):339-346 (Pubitemid 20265379)
    • (1990) British Journal of Dermatology , vol.123 , Issue.3 , pp. 339-346
    • Berman, B.1    Duncan, M.R.2
  • 13
    • 0033678778 scopus 로고    scopus 로고
    • Porphyria cutanea tarda
    • quiz 207-208
    • Bleasel NR, Varigos GA (2000) Porphyria cutanea tarda. Australas J Dermatol 41(4):197-206 (quiz 207-208)
    • (2000) Australas J Dermatol , vol.41 , Issue.4 , pp. 197-206
    • Bleasel, N.R.1    Varigos, G.A.2
  • 14
    • 84866425239 scopus 로고    scopus 로고
    • Aiding and abetting roles of NOX oxidases in cellular transformation
    • doi:10.1038/nrc3339
    • Block K, Gorin Y (2012) Aiding and abetting roles of NOX oxidases in cellular transformation. Nat Rev Cancer 12(9):627-637. doi:10.1038/nrc3339
    • (2012) Nat Rev Cancer , vol.12 , Issue.9 , pp. 627-637
    • Block, K.1    Gorin, Y.2
  • 15
    • 0018356615 scopus 로고
    • The relationship of diphenyleneiodoniuminduced hypoglycaemia to the specific covalent modification of NADH-ubiquinone oxidoreductase
    • Bloxham DP (1979) The relationship of diphenyleneiodoniuminduced hypoglycaemia to the specific covalent modification of NADH-ubiquinone oxidoreductase. Biochem Soc Trans 7(1):103-106
    • (1979) Biochem Soc Trans , vol.7 , Issue.1 , pp. 103-106
    • Bloxham, D.P.1
  • 16
    • 33645706122 scopus 로고    scopus 로고
    • Quality of life of patients with keloid and hypertrophic scarring
    • doi:10.1007/s00403-006-0651-7
    • Bock O, Schmid-Ott G, Malewski P, Mrowietz U (2006) Quality of life of patients with keloid and hypertrophic scarring. Arch Dermatol Res 297(10):433-438. doi:10.1007/s00403-006-0651-7
    • (2006) Arch Dermatol Res , vol.297 , Issue.10 , pp. 433-438
    • Bock, O.1    Schmid-Ott, G.2    Malewski, P.3    Mrowietz, U.4
  • 19
    • 84877042485 scopus 로고    scopus 로고
    • Cytokine mediated tissue fibrosis
    • doi:10.1016/j.bbadis.2012.09.014
    • Borthwick LA, Wynn TA, Fisher AJ (2013) Cytokine mediated tissue fibrosis. Biochim Biophys Acta 1832(7):1049-1060. doi:10.1016/j.bbadis.2012.09. 014
    • (2013) Biochim Biophys Acta , vol.1832 , Issue.7 , pp. 1049-1060
    • Borthwick, L.A.1    Wynn, T.A.2    Fisher, A.J.3
  • 20
    • 0032831589 scopus 로고    scopus 로고
    • Overhydroxylation of lysyl residues is the initial step for altered collagen cross-links and fibril architecture in fibrotic skin
    • DOI 10.1046/j.1523-1747.1999.00735.x
    • Brinckmann J, Notbohm H, Tronnier M, Acil Y, Fietzek PP, Schmeller W, Muller PK, Batge B (1999) Overhydroxylation of lysyl residues is the initial step for altered collagen cross-links and fibril architecture in fibrotic skin. J Invest Dermatol 113(4):617-621. doi:10.1046/j.1523-1747.1999.00735.x (Pubitemid 29489626)
    • (1999) Journal of Investigative Dermatology , vol.113 , Issue.4 , pp. 617-621
    • Brinckmann, J.1    Notbohm, H.2    Tronnier, M.3    Acil, Y.4    Fietzek, P.P.5    Schmeller, W.6    Muller, P.K.7    Batge, B.8
  • 22
    • 4344662914 scopus 로고    scopus 로고
    • Comparison of burst of reactive oxygen species and activation of caspase-3 in apoptosis of K562 and HL-60 cells induced by docetaxel
    • DOI 10.1016/j.canlet.2004.03.047, PII S0304383504002848
    • Cao DX, Qiao B, Ge ZQ, Yuan YJ (2004) Comparison of burst of reactive oxygen species and activation of caspase-3 in apoptosis of K562 and HL-60 cells induced by docetaxel. Cancer Lett 214(1):103-113. doi:10.1016/j.canlet.2004.03. 047 (Pubitemid 39141203)
    • (2004) Cancer Letters , vol.214 , Issue.1 , pp. 103-113
    • Cao, D.-X.1    Qiao, B.2    Ge, Z.-Q.3    Yuan, Y.-J.4
  • 23
    • 0347297564 scopus 로고    scopus 로고
    • The antioxidant (-)-epigallocatechin-3-gallate inhibits activated hepatic stellate cell growth and suppresses acetaldehyde-induced gene expression
    • DOI 10.1042/BJ20020894
    • Chen A, Zhang L, Xu J, Tang J (2002) The antioxidant (-)- epigallocatechin-3-gallate inhibits activated hepatic stellate cell growth and suppresses acetaldehyde-induced gene expression. Biochem J 368(Pt 3):695-704. doi:10.1042/BJ20020894 (Pubitemid 36042671)
    • (2002) Biochemical Journal , vol.368 , Issue.3 , pp. 695-704
    • Chen, A.1    Zhang, L.2    Xu, J.3    Tang, J.4
  • 25
    • 10344231960 scopus 로고    scopus 로고
    • Effects of short-term treatment with vitamin E in systemic sclerosis: A double blind, randomized, controlled clinical trial of efficacy based on urinary isoprostane measurement
    • doi:10.1016/j.freeradbiomed. 2004.09.032
    • Cracowski JL, Girolet S, Imbert B, Seinturier C, Stanke-Labesque F, Bessard J, Boignard A, Bessard G, Carpentier PH (2005) Effects of short-term treatment with vitamin E in systemic sclerosis: a double blind, randomized, controlled clinical trial of efficacy based on urinary isoprostane measurement. Free Radic Biol Med 38(1):98-103. doi:10.1016/j.freeradbiomed. 2004.09.032
    • (2005) Free Radic Biol Med , vol.38 , Issue.1 , pp. 98-103
    • Cracowski, J.L.1    Girolet, S.2    Imbert, B.3    Seinturier, C.4    Stanke-Labesque, F.5    Bessard, J.6    Boignard, A.7    Bessard, G.8    Carpentier, P.H.9
  • 26
    • 27644456575 scopus 로고    scopus 로고
    • NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into myofibroblasts
    • DOI 10.1161/01.RES.0000187457.24338.3D
    • Cucoranu I, Clempus R, Dikalova A, Phelan PJ, Ariyan S, Dikalov S, Sorescu D (2005) NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into myofibroblasts. Circ Res 97(9):900-907. doi:10.1161/01.RES.0000187457.24338.3D (Pubitemid 41552675)
    • (2005) Circulation Research , vol.97 , Issue.9 , pp. 900-907
    • Cucoranu, I.1    Clempus, R.2    Dikalova, A.3    Phelan, P.J.4    Ariyan, S.5    Dikalov, S.6    Sorescu, D.7
  • 27
    • 70549087922 scopus 로고    scopus 로고
    • Telomere shortening may be associated with human keloids
    • doi:10.1186/1471-2350-10-110
    • De Felice B, Wilson RR, Nacca M (2009) Telomere shortening may be associated with human keloids. BMC Med Genet 10:110. doi:10.1186/1471-2350-10- 110
    • (2009) BMC Med Genet , vol.10 , pp. 110
    • De Felice, B.1    Wilson, R.R.2    Nacca, M.3
  • 28
    • 69949120448 scopus 로고    scopus 로고
    • Pentoxifylline in association with vitamin E reduces cutaneous fibrosis in systemic sclerosis
    • doi:10.1007/s10067-009-1202-3
    • de Souza RB, Macedo AR, Kuruma KA, Macedo PA, Borges CT (2009) Pentoxifylline in association with vitamin E reduces cutaneous fibrosis in systemic sclerosis. Clin Rheumatol 28(10):1207-1212. doi:10.1007/s10067-009- 1202-3
    • (2009) Clin Rheumatol , vol.28 , Issue.10 , pp. 1207-1212
    • De Souza, R.B.1    Macedo, A.R.2    Kuruma, K.A.3    Macedo, P.A.4    Borges, C.T.5
  • 29
    • 84855289536 scopus 로고    scopus 로고
    • Modulation of fibrosis in systemic sclerosis by nitric oxide and antioxidants
    • doi:10.1155/2012/521958
    • Dooley A, Bruckdorfer KR, Abraham DJ (2012) Modulation of fibrosis in systemic sclerosis by nitric oxide and antioxidants. Cardiol Res Pract 2012:521958. doi:10.1155/2012/521958
    • (2012) Cardiol Res Pract , vol.2012 , pp. 521958
    • Dooley, A.1    Bruckdorfer, K.R.2    Abraham, D.J.3
  • 30
    • 78649373143 scopus 로고    scopus 로고
    • Modulation of collagen type I, fibronectin and dermal fibroblast function and activity, in systemic sclerosis by the antioxidant epigallocatechin-3- gallate
    • doi:10.1093/rheumatology/keq208
    • Dooley A, Shi-Wen X, Aden N, Tranah T, Desai N, Denton CP, Abraham DJ, Bruckdorfer R (2010) Modulation of collagen type I, fibronectin and dermal fibroblast function and activity, in systemic sclerosis by the antioxidant epigallocatechin-3-gallate. Rheumatology 49(11):2024-2036. doi:10.1093/ rheumatology/keq208
    • (2010) Rheumatology , vol.49 , Issue.11 , pp. 2024-2036
    • Dooley, A.1    Shi-Wen, X.2    Aden, N.3    Tranah, T.4    Desai, N.5    Denton, C.P.6    Abraham, D.J.7    Bruckdorfer, R.8
  • 31
    • 0021017738 scopus 로고
    • Early excision and grafting vs. nonoperative treatment of burns of indeterminant depth: A randomized prospective study
    • Engrav LH, Heimbach DM, Reus JL, Harnar TJ, Marvin JA (1983) Early excision and grafting vs. nonoperative treatment of burns of indeterminant depth: a randomized prospective study. J Trauma 23(11):1001-1004 (Pubitemid 14201197)
    • (1983) Journal of Trauma , vol.23 , Issue.11 , pp. 1001-1004
    • Engrav, L.H.1    Heimbach, D.M.2    Reus, J.L.3
  • 32
    • 0036196091 scopus 로고    scopus 로고
    • Coping with body image changes following a disfiguring burn injury
    • DOI 10.1037//0278-6133.21.2.115
    • Fauerbach JA, Heinberg LJ, Lawrence JW, Bryant AG, Richter L, Spence RJ (2002) Coping with body image changes following a disfiguring burn injury. Health Psychol Off J Div Health Psychol Am Psychol Assoc 21(2):115-121 (Pubitemid 34258866)
    • (2002) Health Psychology , vol.21 , Issue.2 , pp. 115-121
    • Fauerbach, J.A.1    Heinberg, L.J.2    Lawrence, J.W.3    Bryant, A.G.4    Richter, L.5    Spence, R.J.6
  • 34
    • 84863913123 scopus 로고    scopus 로고
    • New insights into the role of oxidative stress in scleroderma fibrosis
    • doi:10.2174/18743129012060 10087
    • Gabrielli A, Svegliati S, Moroncini G, Amico D (2012) New insights into the role of oxidative stress in scleroderma fibrosis. Open Rheumatol J 6:87-95. doi:10.2174/18743129012060 10087
    • (2012) Open Rheumatol J , vol.6 , pp. 87-95
    • Gabrielli, A.1    Svegliati, S.2    Moroncini, G.3    Amico, D.4
  • 35
    • 77958098686 scopus 로고    scopus 로고
    • A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells
    • doi:10.1021/cb100219n
    • Gianni D, Taulet N, Zhang H, DerMardirossian C, Kister J, Martinez L, Roush WR, Brown SJ, Bokoch GM, Rosen H (2010) A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells. ACS Chem Biol 5(10):981-993. doi:10.1021/cb100219n
    • (2010) ACS Chem Biol , vol.5 , Issue.10 , pp. 981-993
    • Gianni, D.1    Taulet, N.2    Zhang, H.3    DerMardirossian, C.4    Kister, J.5    Martinez, L.6    Roush, W.R.7    Brown, S.J.8    Bokoch, G.M.9    Rosen, H.10
  • 36
    • 33750919240 scopus 로고    scopus 로고
    • NADPH oxidases in the kidney
    • DOI 10.1089/ars.2006.8.1597
    • Gill PS, Wilcox CS (2006) NADPH oxidases in the kidney. Antioxid Redox Signal 8(9-10):1597-1607. doi:10.1089/ars.2006.8.1597 (Pubitemid 44726334)
    • (2006) Antioxidants and Redox Signaling , vol.8 , Issue.9-10 , pp. 1597-1607
    • Gill, P.S.1    Wilcox, C.S.2
  • 38
    • 84864356954 scopus 로고    scopus 로고
    • Targeting NOX enzymes in pulmonary fibrosis
    • doi:10.1007/s00018-012-1012-7
    • Hecker L, Cheng J, Thannickal VJ (2012) Targeting NOX enzymes in pulmonary fibrosis. Cell Mol Life Sci 69(14): 2365-2371. doi:10.1007/s00018-012- 1012-7
    • (2012) Cell Mol Life Sci , vol.69 , Issue.14 , pp. 2365-2371
    • Hecker, L.1    Cheng, J.2    Thannickal, V.J.3
  • 39
    • 0029088067 scopus 로고
    • The effects of N-(5-vinyl-1,3-thiazolidin-2-ylidene)phenylamine (5-VTPA) on the changes in free intracellular calcium and the production of reactive oxygen metabolites in human leukocytes
    • Heiskanen KM, Naarala J, Savolainen KM (1995) The effects of N-(5-vinyl-1,3-thiazolidin-2-ylidene)phenylamine (5-VTPA) on the changes in free intracellular calcium and the production of reactive oxygen metabolites in human leukocytes. Toxicology 100(1-3):195-202
    • (1995) Toxicology , vol.100 , Issue.1-3 , pp. 195-202
    • Heiskanen, K.M.1    Naarala, J.2    Savolainen, K.M.3
  • 40
    • 0031567103 scopus 로고    scopus 로고
    • Effects of 3-phenylamino-1,2-propanediol and its mono- and dioleylesters on the production of reactive oxygen metabolites in human polymorphonuclear leukocytes
    • DOI 10.1016/S0378-4274(96)03862-3, PII S0378427496038623
    • Heiskanen KM, Savolainen KM (1997) Effects of 3-phenylamino-1,2- propanediol and its mono- and dioleylesters on the production of reactive oxygen metabolites in human polymorphonuclear leukocytes. Toxicol Lett 91(1):39-45 (Pubitemid 27148677)
    • (1997) Toxicology Letters , vol.91 , Issue.1 , pp. 39-45
    • Heiskanen, K.M.1    Savolainen, K.M.2
  • 41
    • 38549138327 scopus 로고    scopus 로고
    • Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant
    • DOI 10.1161/HYPERTENSIONAHA.107.100214, PII 0000426820080200000011
    • Heumuller S, Wind S, Barbosa-Sicard E, Schmidt HH, Busse R, Schroder K, Brandes RP (2008) Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant. Hypertension 51(2):211-217. doi:10.1161/HYPERTENSIONAHA.107.100214 (Pubitemid 351159930)
    • (2008) Hypertension , vol.51 , Issue.2 , pp. 211-217
    • Heumuller, S.1    Wind, S.2    Barbosa-Sicard, E.3    Schmidt, H.H.H.W.4    Busse, R.5    Schroder, K.6    Brandes, R.P.7
  • 43
    • 0034798748 scopus 로고    scopus 로고
    • Evidence for increased pyridinoline concentration in fibrotic tissues in diffuse systemic sclerosis
    • DOI 10.1046/j.1365-2230.2001.00886.x
    • Istok R, Bely M, Stancikova M, Rovensky J (2001) Evidence for increased pyridinoline concentration in fibrotic tissues in diffuse systemic sclerosis. Clin Exp Dermatol 26(6):545-547 (Pubitemid 32955471)
    • (2001) Clinical and Experimental Dermatology , vol.26 , Issue.6 , pp. 545-547
    • Istok, R.1    Bely, M.2    Stancikova, M.3    Rovensky, J.4
  • 45
    • 79955006810 scopus 로고    scopus 로고
    • Dose-dependent antioxidant function of resveratrol demonstrated via modulation of reactive oxygen species in normal human skin fibroblasts in vitro
    • Jagdeo J, Adams L, Lev-Tov H, Sieminska J, Michl J, Brody N (2010) Dose-dependent antioxidant function of resveratrol demonstrated via modulation of reactive oxygen species in normal human skin fibroblasts in vitro. J Drugs Dermatol 9(12):1523-1526
    • (2010) J Drugs Dermatol , vol.9 , Issue.12 , pp. 1523-1526
    • Jagdeo, J.1    Adams, L.2    Lev-Tov, H.3    Sieminska, J.4    Michl, J.5    Brody, N.6
  • 46
    • 80053067267 scopus 로고    scopus 로고
    • Complementary antioxidant function of caffeine and green tea polyphenols in normal human skin fibroblasts
    • Jagdeo J, Brody N (2011) Complementary antioxidant function of caffeine and green tea polyphenols in normal human skin fibroblasts. J Drugs Dermatol 10(7):753-761
    • (2011) J Drugs Dermatol , vol.10 , Issue.7 , pp. 753-761
    • Jagdeo, J.1    Brody, N.2
  • 47
    • 75649096395 scopus 로고    scopus 로고
    • Mechanisms of skin fibrosis in systemic sclerosis
    • doi:10.1111/j.1346-8138.2009.00738.x
    • Jinnin M (2010) Mechanisms of skin fibrosis in systemic sclerosis. J Dermatol 37(1):11-25. doi:10.1111/j.1346-8138.2009.00738.x
    • (2010) J Dermatol , vol.37 , Issue.1 , pp. 11-25
    • Jinnin, M.1
  • 48
    • 4744362174 scopus 로고    scopus 로고
    • Interleukin-13 stimulates the transcription of the human alpha2(I) collagen gene in human dermal fibroblasts
    • DOI 10.1074/jbc.M406951200
    • Jinnin M, Ihn H, Yamane K, Tamaki K (2004) Interleukin-13 stimulates the transcription of the human alpha2(I) collagen gene in human dermal fibroblasts. J Biol Chem 279(40): 41783-41791. doi:10.1074/jbc.M406951200 (Pubitemid 39313625)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.40 , pp. 41783-41791
    • Jinnin, M.1    Ihn, H.2    Yamane, K.3    Tamaki, K.4
  • 50
    • 84861181733 scopus 로고    scopus 로고
    • Arsenic trioxide prevents murine sclerodermatous graft-versus-host disease
    • doi:10.4049/jimmunol.1103538
    • Kavian N, Marut W, Servettaz A, Laude H, Nicco C, Chereau C, Weill B, Batteux F (2012) Arsenic trioxide prevents murine sclerodermatous graft-versus-host disease. J Immunol 188(10): 5142-5149. doi:10.4049/jimmunol. 1103538
    • (2012) J Immunol , vol.188 , Issue.10 , pp. 5142-5149
    • Kavian, N.1    Marut, W.2    Servettaz, A.3    Laude, H.4    Nicco, C.5    Chereau, C.6    Weill, B.7    Batteux, F.8
  • 51
    • 84897579418 scopus 로고    scopus 로고
    • The Extracellular matrix
    • Bender DA, Botham KM, Weil PA, Kennelly PJ, Murray RK, Rodwell VW (eds) 29th edn. McGraw-Hill, New York
    • Keeley FW, Murray RK (2011) The Extracellular matrix. In: Bender DA, Botham KM, Weil PA, Kennelly PJ, Murray RK, Rodwell VW (eds) Harper's illustrated biochemistry, 29th edn. McGraw-Hill, New York
    • (2011) Harper's Illustrated Biochemistry
    • Keeley, F.W.1    Murray, R.K.2
  • 53
    • 84862794583 scopus 로고    scopus 로고
    • Neuregulin induces CTGF expression in hypertrophic scarring fibroblasts
    • doi:10.1007/s11010-012-1258-2
    • Kim JS, Choi IG, Lee BC, Park JB, Kim JH, Jeong JH, Jeong JH, Seo CH (2012) Neuregulin induces CTGF expression in hypertrophic scarring fibroblasts. Mol Cell Biochem 365(1-2):181-189. doi:10.1007/s11010-012-1258-2
    • (2012) Mol Cell Biochem , vol.365 , Issue.1-2 , pp. 181-189
    • Kim, J.S.1    Choi, I.G.2    Lee, B.C.3    Park, J.B.4    Kim, J.H.5    Jeong, J.H.6    Jeong, J.H.7    Seo, C.H.8
  • 54
  • 55
    • 84855394414 scopus 로고    scopus 로고
    • Fibrotic and sclerotic manifestations of chronic graft-versus-host disease
    • doi:10.1016/j.bbmt.2011.10.021
    • Kitko CL, White ES, Baird K (2012) Fibrotic and sclerotic manifestations of chronic graft-versus-host disease. Biol Blood Marrow Transpl J Am Soc Blood Marrow Transpl 18(Suppl 1):S46-S52. doi:10.1016/j.bbmt.2011.10.021
    • (2012) Biol Blood Marrow Transpl J Am Soc Blood Marrow Transpl , vol.18 , Issue.SUPPL. 1
    • Kitko, C.L.1    White, E.S.2    Baird, K.3
  • 56
    • 74549137815 scopus 로고    scopus 로고
    • The effect of epigallocatechin-3-gallate, a constituent of green tea, on transforming growth factor-beta1-stimulated wound contraction
    • doi:10.1111/j.1524-475X.2009.00552.x
    • Klass BR, Branford OA, Grobbelaar AO, Rolfe KJ (2010) The effect of epigallocatechin-3-gallate, a constituent of green tea, on transforming growth factor-beta1-stimulated wound contraction. Wound Repair Regen Off Publ Wound Heal Soc Eur Tissue Repair Soc 18(1):80-88. doi:10.1111/j.1524-475X.2009.00552.x
    • (2010) Wound Repair Regen off Publ Wound Heal Soc Eur Tissue Repair Soc , vol.18 , Issue.1 , pp. 80-88
    • Klass, B.R.1    Branford, O.A.2    Grobbelaar, A.O.3    Rolfe, K.J.4
  • 59
    • 47149098182 scopus 로고    scopus 로고
    • NOX enzymes as novel targets for drug development
    • doi:10.1007/s00281-008-0123-6
    • Lambeth JD, Krause KH, Clark RA (2008) NOX enzymes as novel targets for drug development. Semin Immunopathol 30(3):339-363. doi:10.1007/s00281-008-0123- 6
    • (2008) Semin Immunopathol , vol.30 , Issue.3 , pp. 339-363
    • Lambeth, J.D.1    Krause, K.H.2    Clark, R.A.3
  • 60
    • 0025098828 scopus 로고
    • Collagen cross-linking in adult patients with acute and chronic fibrotic lung disease. Molecular markers for fibrotic collagen
    • Last JA, King TE Jr, Nerlich AG, Reiser KM (1990) Collagen cross-linking in adult patients with acute and chronic fibrotic lung disease. Molecular markers for fibrotic collagen. Am Rev Respir Dis 141(2):307-313. doi:10.1164/ajrccm/141.2.307 (Pubitemid 20068865)
    • (1990) American Review of Respiratory Disease , vol.141 , Issue.2 I , pp. 307-313
    • Last, J.A.1    King Jr., T.E.2    Nerlich, A.G.3    Reiser, K.M.4
  • 61
    • 84864403641 scopus 로고    scopus 로고
    • Role of NADPH oxidase/ROS in proinflammatory mediators-induced airway and pulmonary diseases
    • doi:10.1016/j.bcp.2012.05.005
    • Lee IT, Yang CM (2012) Role of NADPH oxidase/ROS in proinflammatory mediators-induced airway and pulmonary diseases. Biochem Pharmacol 84(5):581-590. doi:10.1016/j.bcp.2012.05.005
    • (2012) Biochem Pharmacol , vol.84 , Issue.5 , pp. 581-590
    • Lee, I.T.1    Yang, C.M.2
  • 62
    • 58149498955 scopus 로고    scopus 로고
    • Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice
    • doi:10.1152/ajplung.90411.2008
    • Lee J, Reddy R, Barsky L, Scholes J, Chen H, Shi W, Driscoll B (2009) Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice. Am J Physiol Lung Cell Mol Physiol 296(1):L57-L70. doi:10.1152/ajplung. 90411.2008
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.296 , Issue.1
    • Lee, J.1    Reddy, R.2    Barsky, L.3    Scholes, J.4    Chen, H.5    Shi, W.6    Driscoll, B.7
  • 64
    • 78650798178 scopus 로고    scopus 로고
    • CCN2 is required for bleomycin-induced skin fibrosis in mice
    • doi:10.1002/art.30074
    • Liu S, Shi-wen X, Abraham DJ, Leask A (2011) CCN2 is required for bleomycin-induced skin fibrosis in mice. Arthr Rheum 63(1):239-246. doi:10.1002/art.30074
    • (2011) Arthr Rheum , vol.63 , Issue.1 , pp. 239-246
    • Liu, S.1    Shi-wen, X.2    Abraham, D.J.3    Leask, A.4
  • 65
    • 29644432536 scopus 로고    scopus 로고
    • Paclitaxel modulates TGFbeta signaling in scleroderma skin grafts in immunodeficient mice
    • doi:10.1371/journal.pmed.0020354
    • Liu X, Zhu S, Wang T, Hummers L, Wigley FM, Goldschmidt-Clermont PJ, Dong C (2005) Paclitaxel modulates TGFbeta signaling in scleroderma skin grafts in immunodeficient mice. PLoS Med 2(12):e354. doi:10.1371/journal.pmed.0020354
    • (2005) PLoS Med , vol.2 , Issue.12
    • Liu, X.1    Zhu, S.2    Wang, T.3    Hummers, L.4    Wigley, F.M.5    Goldschmidt-Clermont, P.J.6    Dong, C.7
  • 66
    • 0032913414 scopus 로고    scopus 로고
    • Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells
    • DOI 10.1002/(SICI)1097-4652(199906)179:3<297::AID-
    • Lu R, Serrero G (1999) Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells. J Cell Physiol 179(3):297-304. doi:10.1002/(SICI)1097-4652(199906)179:3\ 297:AID-JCP7[3.0.CO;2-P (Pubitemid 29203154)
    • (1999) Journal of Cellular Physiology , vol.179 , Issue.3 , pp. 297-304
    • Lu, R.1    Serrero, G.2
  • 67
    • 23844434686 scopus 로고    scopus 로고
    • The absence of reactive oxygen species production protects mice against bleomycin-induced pulmonary fibrosis
    • doi:10. 1186/1465-9921-6-11
    • Manoury B, Nenan S, Leclerc O, Guenon I, Boichot E, Planquois JM, Bertrand CP, Lagente V (2005) The absence of reactive oxygen species production protects mice against bleomycin-induced pulmonary fibrosis. Respir Res 6:11. doi:10. 1186/1465-9921-6-11
    • (2005) Respir Res , vol.6 , pp. 11
    • Manoury, B.1    Nenan, S.2    Leclerc, O.3    Guenon, I.4    Boichot, E.5    Planquois, J.M.6    Bertrand, C.P.7    Lagente, V.8
  • 70
    • 34249985040 scopus 로고    scopus 로고
    • Effects of epigallocatechin gallate on diethyldithiocarbamate-induced pancreatic fibrosis in rats
    • DOI 10.1248/bpb.30.1091
    • Meng M, Li YQ, Yan MX, Kou Y, Ren HB (2007) Effects of epigallocatechin gallate on diethyldithiocarbamate-induced pancreatic fibrosis in rats. Biol Pharm Bull 30(6):1091-1096 (Pubitemid 46883874)
    • (2007) Biological and Pharmaceutical Bulletin , vol.30 , Issue.6 , pp. 1091-1096
    • Meng, M.1    Li, Y.-Q.2    Yan, M.-X.3    Kou, Y.4    Ren, H.-B.5
  • 73
    • 84860842229 scopus 로고    scopus 로고
    • Psychiatric symptoms and quality of life in systemic sclerosis
    • doi:10.2174/1745017901208010030
    • Mura G, Bhat KM, Pisano A, Licci G, Carta M (2012) Psychiatric symptoms and quality of life in systemic sclerosis. Clini Pract Epidemiol Mental Health 8:30-35. doi:10.2174/1745017901208010030
    • (2012) Clini Pract Epidemiol Mental Health , vol.8 , pp. 30-35
    • Mura, G.1    Bhat, K.M.2    Pisano, A.3    Licci, G.4    Carta, M.5
  • 74
    • 0027518266 scopus 로고
    • A radical proposal for the pathogenesis of scleroderma
    • Murrell DF (1993) A radical proposal for the pathogenesis of scleroderma. J Am Acad Dermatol 28(1):78-85
    • (1993) J Am Acad Dermatol , vol.28 , Issue.1 , pp. 78-85
    • Murrell, D.F.1
  • 75
    • 0037169525 scopus 로고    scopus 로고
    • Ebselen, a glutathione peroxidase mimetic seleno-organic compound, as a multifunctional antioxidant. Implication for inflammation-associated carcinogenesis
    • DOI 10.1074/jbc.M109641200
    • Nakamura Y, Feng Q, Kumagai T, Torikai K, Ohigashi H, Osawa T, Noguchi N, Niki E, Uchida K (2002) Ebselen, a glutathione peroxidase mimetic seleno-organic compound, as a multifunctional antioxidant. Implication for inflammation-associated carcinogenesis. J Biol Chem 277(4):2687-2694. doi:10.1074/jbc.M109641200 (Pubitemid 34953296)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.4 , pp. 2687-2694
    • Nakamura, Y.1    Feng, Q.2    Kumagai, T.3    Torikai, K.4    Ohigashi, H.5    Osawa, T.6    Noguchi, N.7    Niki, E.8    Uchida, K.9
  • 76
    • 51749085805 scopus 로고    scopus 로고
    • Green tea polyphenol epigallocatechin-3-gallate suppresses collagen production and proliferation in keloid fibroblasts via inhibition of the STAT3-signaling pathway
    • doi:10.1038/jid.2008.103
    • Park G, Yoon BS, Moon JH, Kim B, Jun EK, Oh S, Kim H, Song HJ, Noh JY, Oh C, You S (2008) Green tea polyphenol epigallocatechin-3-gallate suppresses collagen production and proliferation in keloid fibroblasts via inhibition of the STAT3-signaling pathway. J Invest Dermatol 128(10):2429-2441. doi:10.1038/jid.2008.103
    • (2008) J Invest Dermatol , vol.128 , Issue.10 , pp. 2429-2441
    • Park, G.1    Yoon, B.S.2    Moon, J.H.3    Kim, B.4    Jun, E.K.5    Oh, S.6    Kim, H.7    Song, H.J.8    Noh, J.Y.9    Oh, C.10    You, S.11
  • 77
    • 0036444013 scopus 로고    scopus 로고
    • High-dose vitamin E lowers urine porphyrin levels in patients affected by porphyria cutanea tarda
    • doi:10.1006/phrs 2002.0956
    • Pinelli A, Trivulzio S, Tomasoni L, Bertolini B, Pinelli G (2002) High-dose vitamin E lowers urine porphyrin levels in patients affected by porphyria cutanea tarda. Pharmacol Res Off J Italian Pharmacol Soc 45(4):355-359. doi:10.1006/phrs 2002.0956
    • (2002) Pharmacol Res off J Italian Pharmacol Soc , vol.45 , Issue.4 , pp. 355-359
    • Pinelli, A.1    Trivulzio, S.2    Tomasoni, L.3    Bertolini, B.4    Pinelli, G.5
  • 78
    • 1442271244 scopus 로고    scopus 로고
    • Halofuginone to treat fibrosis in chronic graft-versus-host disease and scleroderma
    • DOI 10.1016/S1083-8791(03)00151-4, PII S1083879103001514
    • Pines M, Snyder D, Yarkoni S, Nagler A (2003) Halofuginone to treat fibrosis in chronic graft-versus-host disease and scleroderma. Biol Blood Marrow Transpl J Am Soc Blood Marrow Transpl 9(7):417-425 (Pubitemid 38351799)
    • (2003) Biology of Blood and Marrow Transplantation , vol.9 , Issue.7 , pp. 417-425
    • Pines, M.1    Snyder, D.2    Yarkoni, S.3    Nagler, A.4
  • 79
    • 0036139411 scopus 로고    scopus 로고
    • Modelling telomere shortening and the role of oxidative stress
    • DOI 10.1016/S0047-6374(01)00380-3, PII S0047637401003803
    • Proctor CJ, Kirkwood TB (2002) Modelling telomere shortening and the role of oxidative stress. Mech Ageing Dev 123(4):351-363 (Pubitemid 34024923)
    • (2002) Mechanisms of Ageing and Development , vol.123 , Issue.4 , pp. 351-363
    • Proctor, C.J.1    Kirkwood, T.B.L.2
  • 80
    • 79955611732 scopus 로고    scopus 로고
    • XPC silencing in normal human keratinocytes triggers metabolic alterations through NOX-1 activation-mediated reactive oxygen species
    • doi:10.1016/j.bbabio.2010.12.006
    • Rezvani HR, Rossignol R, Ali N, Benard G, Tang X, Yang HS, Jouary T, de Verneuil H, Taieb A, Kim AL, Mazurier F (2011) XPC silencing in normal human keratinocytes triggers metabolic alterations through NOX-1 activation-mediated reactive oxygen species. Biochim Biophys Acta 1807(6):609-619. doi:10.1016/j.bbabio.2010.12.006
    • (2011) Biochim Biophys Acta , vol.1807 , Issue.6 , pp. 609-619
    • Rezvani, H.R.1    Rossignol, R.2    Ali, N.3    Benard, G.4    Tang, X.5    Yang, H.S.6    Jouary, T.7    De Verneuil, H.8    Taieb, A.9    Kim, A.L.10    Mazurier, F.11
  • 81
    • 0026524310 scopus 로고
    • Hydroxypyridinium collagen cross-links in human liver fibrosis: Study of alveolar echinococcosis
    • Ricard-Blum S, Bresson-Hadni S, Vuitton DA, Ville G, Grimaud JA (1992) Hydroxypyridinium collagen cross-links in human liver fibrosis: study of alveolar echinococcosis. Hepatology 15(4):599-602
    • (1992) Hepatology , vol.15 , Issue.4 , pp. 599-602
    • Ricard-Blum, S.1    Bresson-Hadni, S.2    Vuitton, D.A.3    Ville, G.4    Grimaud, J.A.5
  • 82
    • 0027690945 scopus 로고
    • Collagen crosslinking by pyridinoline occurs in non-reversible skin fibrosis
    • Ricard-Blum S, Esterre P, Grimaud JA (1993) Collagen crosslinking by pyridinoline occurs in non-reversible skin fibrosis. Cell Mol Biol 39(7):723-727
    • (1993) Cell Mol Biol , vol.39 , Issue.7 , pp. 723-727
    • Ricard-Blum, S.1    Esterre, P.2    Grimaud, J.A.3
  • 83
    • 84868305344 scopus 로고    scopus 로고
    • TGF-beta signaling in tissue fibrosis: Redox controls, target genes and therapeutic opportunities
    • doi:10.1016/j.cellsig.2012.10.003
    • Samarakoon R, Overstreet JM, Higgins PJ (2013) TGF-beta signaling in tissue fibrosis: redox controls, target genes and therapeutic opportunities. Cell Signal 25(1):264-268. doi:10.1016/j.cellsig.2012.10.003
    • (2013) Cell Signal , vol.25 , Issue.1 , pp. 264-268
    • Samarakoon, R.1    Overstreet, J.M.2    Higgins, P.J.3
  • 84
    • 0035149214 scopus 로고    scopus 로고
    • Oxidative stress in scleroderma: Maintenance of scleroderma fibroblast phenotype by the constitutive up-regulation of reactive oxygen species generation through the NADPH oxidase complex pathway
    • DOI 10.1002/1529-0131(200111)44:11<2653::AID-ART44
    • Sambo P, Baroni SS, Luchetti M, Paroncini P, Dusi S, Orlandini G, Gabrielli A (2001) Oxidative stress in scleroderma: maintenance of scleroderma fibroblast phenotype by the constitutive up-regulation of reactive oxygen species generation through the NADPH oxidase complex pathway. Arthr Rheum 44(11):2653-2664 (Pubitemid 33049343)
    • (2001) Arthritis and Rheumatism , vol.44 , Issue.11 , pp. 2653-2664
    • Sambo, P.1    Baroni, S.S.2    Luchetti, M.3    Paroncini, P.4    Dusi, S.5    Orlandini, G.6    Gabrielli, A.7
  • 85
    • 84869058572 scopus 로고    scopus 로고
    • Therapeutic targeting of redox signaling in myofibroblast differentiation and agerelated fibrotic disease
    • doi:10.1155/2012/458276
    • Sampson N, Berger P, Zenzmaier C (2012) Therapeutic targeting of redox signaling in myofibroblast differentiation and agerelated fibrotic disease. Oxidative Med Cell Longev 2012: 458276. doi:10.1155/2012/458276
    • (2012) Oxidative Med Cell Longev , vol.2012 , pp. 458276
    • Sampson, N.1    Berger, P.2    Zenzmaier, C.3
  • 86
    • 84866183230 scopus 로고    scopus 로고
    • Targeting NADPH oxidases in vascular pharmacology
    • doi:10.1016/j.vph.2012.02.012
    • Schramm A, Matusik P, Osmenda G, Guzik TJ (2012) Targeting NADPH oxidases in vascular pharmacology. Vascul Pharmacol 56(5-6):216-231. doi:10.1016/j.vph.2012.02.012
    • (2012) Vascul Pharmacol , vol.56 , Issue.5-6 , pp. 216-231
    • Schramm, A.1    Matusik, P.2    Osmenda, G.3    Guzik, T.J.4
  • 88
    • 84861221498 scopus 로고    scopus 로고
    • Lamins as mediators of oxidative stress
    • doi:10.1016/j.bbrc.2012.04.058
    • Sieprath T, Darwiche R, De Vos WH (2012) Lamins as mediators of oxidative stress. Biochem Biophys Res Commun 421(4):635-639. doi:10.1016/j.bbrc.2012.04. 058
    • (2012) Biochem Biophys Res Commun , vol.421 , Issue.4 , pp. 635-639
    • Sieprath, T.1    Darwiche, R.2    De Vos, W.H.3
  • 89
    • 0034735897 scopus 로고    scopus 로고
    • Emerging potentials for an antioxidant therapy as a new approach to the treatment of systemic sclerosis
    • Simonini G, Pignone A, Generini S, Falcini F, Cerinic MM (2000) Emerging potentials for an antioxidant therapy as a new approach to the treatment of systemic sclerosis. Toxicology 155(1-3):1-15
    • (2000) Toxicology , vol.155 , Issue.1-3 , pp. 1-15
    • Simonini, G.1    Pignone, A.2    Generini, S.3    Falcini, F.4    Cerinic, M.M.5
  • 90
    • 84880917678 scopus 로고    scopus 로고
    • Lack of association of platelet-derived growth factor (PDGF) receptor autoantibodies and severity of chronic graft-versus-host disease (GvHD)
    • doi:10.1007/s00432-013-1451-z
    • Spies-Weisshart B, Schilling K, Bohmer F, Hochhaus A, Sayer HG, Scholl S (2013) Lack of association of platelet-derived growth factor (PDGF) receptor autoantibodies and severity of chronic graft-versus-host disease (GvHD). J Cancer Res Clin Oncol 139(8):1397-1404. doi:10.1007/s00432-013-1451-z
    • (2013) J Cancer Res Clin Oncol , vol.139 , Issue.8 , pp. 1397-1404
    • Spies-Weisshart, B.1    Schilling, K.2    Bohmer, F.3    Hochhaus, A.4    Sayer, H.G.5    Scholl, S.6
  • 91
    • 34547136451 scopus 로고    scopus 로고
    • Mineralocorticoid receptor blockade attenuates chronic overexpression of the renin-angiotensin-aldosterone system stimulation of reduced nicotinamide adenine dinucleotide phosphate oxidase and cardiac remodeling
    • DOI 10.1210/en.2006-1691
    • Stas S, Whaley-Connell A, Habibi J, Appesh L, Hayden MR, Karuparthi PR, Qazi M, Morris EM, Cooper SA, Link CD, Stump C, Hay M, Ferrario C, Sowers JR (2007) Mineralocorticoid receptor blockade attenuates chronic overexpression of the renin-angiotensin-aldosterone system stimulation of reduced nicotinamide adenine dinucleotide phosphate oxidase and cardiac remodeling. Endocrinology 148(8):3773-3780. doi:10.1210/en.2006-1691 (Pubitemid 47105865)
    • (2007) Endocrinology , vol.148 , Issue.8 , pp. 3773-3780
    • Stas, S.1    Whaley-Connell, A.2    Habibi, J.3    Appesh, L.4    Hayden, M.R.5    Karuparthi, P.R.6    Qazi, M.7    Morris, E.M.8    Cooper, S.A.9    Link, C.D.10    Stump, C.11    Hay, M.12    Ferrario, C.13    Sowers, J.R.14
  • 92
    • 33646035513 scopus 로고    scopus 로고
    • Novel Nox inhibitor of oxLDLinduced reactive oxygen species formation in human endothelial cells
    • doi:10.1016/j.bbrc.2006.03.114
    • Stielow C, Catar RA, Muller G, Wingler K, Scheurer P, Schmidt HH, Morawietz H (2006) Novel Nox inhibitor of oxLDLinduced reactive oxygen species formation in human endothelial cells. Biochem Biophys Res Commun 344(1):200-205. doi:10.1016/j.bbrc.2006.03.114
    • (2006) Biochem Biophys Res Commun , vol.344 , Issue.1 , pp. 200-205
    • Stielow, C.1    Catar, R.A.2    Muller, G.3    Wingler, K.4    Scheurer, P.5    Schmidt, H.H.6    Morawietz, H.7
  • 94
    • 47549114629 scopus 로고    scopus 로고
    • Spironolactone exhibits direct renoprotective effects and inhibits renal renin-angiotensin-aldosterone system in diabetic rats
    • doi:10.1016/j.ejphar.2008.06.019
    • Taira M, Toba H, Murakami M, Iga I, Serizawa R, Murata S, Kobara M, Nakata T (2008) Spironolactone exhibits direct renoprotective effects and inhibits renal renin-angiotensin-aldosterone system in diabetic rats. Eur J Pharmacol 589(1-3): 264-271. doi:10.1016/j.ejphar.2008.06.019
    • (2008) Eur J Pharmacol , vol.589 , Issue.1-3 , pp. 264-271
    • Taira, M.1    Toba, H.2    Murakami, M.3    Iga, I.4    Serizawa, R.5    Murata, S.6    Kobara, M.7    Nakata, T.8
  • 95
    • 77953279213 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate (EGCG) reduces liver inflammation, oxidative stress and fibrosis in carbon tetrachloride (CCl4)-induced liver injury in mice
    • doi:10.1016/j.tox.2010.04.014
    • Tipoe GL, Leung TM, Liong EC, Lau TY, Fung ML, Nanji AA (2010) Epigallocatechin-3-gallate (EGCG) reduces liver inflammation, oxidative stress and fibrosis in carbon tetrachloride (CCl4)-induced liver injury in mice. Toxicology 273(1-3):45-52. doi:10.1016/j.tox.2010.04.014
    • (2010) Toxicology , vol.273 , Issue.1-3 , pp. 45-52
    • Tipoe, G.L.1    Leung, T.M.2    Liong, E.C.3    Lau, T.Y.4    Fung, M.L.5    Nanji, A.A.6
  • 97
    • 34248355179 scopus 로고    scopus 로고
    • Angiotensin-TGF-beta1 crosstalk in human idiopathic pulmonary fibrosis: Autocrine mechanisms in myofibroblasts and macrophages
    • DOI 10.2174/138161207780618885
    • Uhal BD, Kim JK, Li X, Molina-Molina M (2007) Angiotensin- TGF-beta 1 crosstalk in human idiopathic pulmonary fibrosis: autocrine mechanisms in myofibroblasts and macrophages. Curr Pharm Des 13(12):1247-1256 (Pubitemid 46739332)
    • (2007) Current Pharmaceutical Design , vol.13 , Issue.12 , pp. 1247-1256
    • Uhal, B.D.1    Kim, J.K.2    Li, X.3    Molina-Molina, M.4
  • 99
    • 3543032204 scopus 로고    scopus 로고
    • Increased formation of pyridinoline cross-links due to higher telopeptide lysyl hydroxylase levels is a general fibrotic phenomenon
    • DOI 10.1016/j.matbio.2004.06.001, PII S0945053X04000678
    • van der Slot AJ, Zuurmond AM, van den Bogaerdt AJ, Ulrich MM, Middelkoop E, Boers W, Karel Ronday H, DeGroot J, Huizinga TW, Bank RA (2004) Increased formation of pyridinoline cross-links due to higher telopeptide lysyl hydroxylase levels is a general fibrotic phenomenon. Matrix Biol J Int Soc Matrix Biol 23(4):251-257. doi:10.1016/j.matbio.2004.06.001 (Pubitemid 39013983)
    • (2004) Matrix Biology , vol.23 , Issue.4 , pp. 251-257
    • Van Der, S.A.J.1    Zuurmond, A.-M.2    Van Den, B.A.J.3    Ulrich, M.M.W.4    Middelkoop, E.5    Boers, W.6    Karel, R.H.7    Degroot, J.8    Huizinga, T.W.J.9    Bank, R.A.10
  • 100
    • 24944553603 scopus 로고    scopus 로고
    • Systemic sclerosis (scleroderma) and related disorders
    • 18th edn. McGraw-Hill, New York
    • Varga J (2012) Systemic sclerosis (scleroderma) and related disorders. Harrison's Principles of Internal Medicine, 18th edn. McGraw-Hill, New York
    • (2012) Harrison's Principles of Internal Medicine
    • Varga, J.1
  • 101
    • 84863930652 scopus 로고    scopus 로고
    • Role of microRNAs in fibrosis
    • doi:10.2174/187431 2901206010130
    • Vettori S, Gay S, Distler O (2012) Role of microRNAs in fibrosis. Open Rheumatol J 6:130-139. doi:10.2174/187431 2901206010130
    • (2012) Open Rheumatol J , vol.6 , pp. 130-139
    • Vettori, S.1    Gay, S.2    Distler, O.3
  • 102
    • 18144371956 scopus 로고    scopus 로고
    • Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts
    • DOI 10.1096/fj.04-2882fje
    • Waghray M, Cui Z, Horowitz JC, Subramanian IM, Martinez FJ, Toews GB, Thannickal VJ (2005) Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts. FASEB J Off Publ Fed Am Soc Exp Biol 19(7):854-856. doi:10.1096/fj.04-2882fje (Pubitemid 40617407)
    • (2005) FASEB Journal , vol.19 , Issue.7 , pp. 854-856
    • Waghray, M.1    Cui, Z.2    Horowitz, J.C.3    Subramanian, I.M.4    Martinez, F.J.5    Toews, G.B.6    Thannickal, V.J.7
  • 103
    • 84869179668 scopus 로고    scopus 로고
    • Nephrogenic systemic fibrosis: Evidence for oxidative stress and bone marrow-derived fibrocytes in skin, liver, and heart lesions using a 5/6 nephrectomy rodent model
    • doi:10.1016/j.ajpath.2012.08.026
    • Wagner B, Tan C, Barnes JL, Ahuja S, Davis TL, Gorin Y, Jimenez F (2012) Nephrogenic systemic fibrosis: evidence for oxidative stress and bone marrow-derived fibrocytes in skin, liver, and heart lesions using a 5/6 nephrectomy rodent model. Am J Pathol 181(6):1941-1952. doi:10.1016/j.ajpath. 2012.08.026
    • (2012) Am J Pathol , vol.181 , Issue.6 , pp. 1941-1952
    • Wagner, B.1    Tan, C.2    Barnes, J.L.3    Ahuja, S.4    Davis, T.L.5    Gorin, Y.6    Jimenez, F.7
  • 104
    • 0033011728 scopus 로고    scopus 로고
    • Free radical involvement in hypertrophic scar formation
    • DOI 10.1016/S0891-5849(98)00245-7, PII S0891584998002457
    • Wan KC, Evans JH (1999) Free radical involvement in hypertrophic scar formation. Free Radic Biol Med 26(5-6):603-608 (Pubitemid 29146262)
    • (1999) Free Radical Biology and Medicine , vol.26 , Issue.5-6 , pp. 603-608
    • Wan, K.C.1    Evans, J.H.2
  • 105
    • 0036408886 scopus 로고    scopus 로고
    • Effects of antioxidants on pyridinoline cross-link formation in culture supernatants of fibroblasts from normal skin and hypertrophic scars
    • DOI 10.1046/j.1365-2230.2002.01096.x
    • Wan KC, Wu HT, Chan HP, Hung LK (2002) Effects of antioxidants on pyridinoline cross-link formation in culture supernatants of fibroblasts from normal skin and hypertrophic scars. Clin Exp Dermatol 27(6):507-512 (Pubitemid 35278946)
    • (2002) Clinical and Experimental Dermatology , vol.27 , Issue.6 , pp. 507-512
    • Wan, K.C.1    Chan, H.P.2    Hung, L.K.3    Wu, H.T.4
  • 106
    • 34147192256 scopus 로고    scopus 로고
    • Contribution of different Nox homologues to cardiac remodeling in two-kidney two-clip renovascular hypertensive rats: Effect of valsartan
    • DOI 10.1016/j.phrs.2007.01.016, PII S1043661807000400
    • Wang P, Tang F, Li R, Zhang H, Chen S, Liu P, Huang H (2007) Contribution of different Nox homologues to cardiac remodeling in two-kidney two-clip renovascular hypertensive rats: effect of valsartan. Pharmacol Res Off J Italian Pharmacol Soc 55(5):408-417. doi:10.1016/j.phrs.2007.01.016 (Pubitemid 46560393)
    • (2007) Pharmacological Research , vol.55 , Issue.5 , pp. 408-417
    • Wang, P.1    Tang, F.2    Li, R.3    Zhang, H.4    Chen, S.5    Liu, P.6    Huang, H.7
  • 107
    • 0035076514 scopus 로고    scopus 로고
    • Restrictive dermopathy: Report of a case and review of the literature
    • DOI 10.1034/j.1600-0560.2001.028004211.x
    • Wesche WA, Cutlan RT, Khare V, Chesney T, Shanklin D (2001) Restrictive dermopathy: report of a case and review of the literature. J Cutan Pathol 28(4):211-218 (Pubitemid 32234727)
    • (2001) Journal of Cutaneous Pathology , vol.28 , Issue.4 , pp. 211-218
    • Wesche, W.A.1    Cutlan, R.T.2    Khare, V.3    Chesney, T.4    Shanklin, D.5
  • 109
    • 79957890774 scopus 로고    scopus 로고
    • NOX1, 2, 4, 5: Counting out oxidative stress
    • doi:10.1111/j.1476-5381.2011.01249.x
    • Wingler K, Hermans JJ, Schiffers P, Moens A, Paul M, Schmidt HH (2011) NOX1, 2, 4, 5: counting out oxidative stress. Br J Pharmacol 164(3):866-883. doi:10.1111/j.1476-5381.2011.01249.x
    • (2011) Br J Pharmacol , vol.164 , Issue.3 , pp. 866-883
    • Wingler, K.1    Hermans, J.J.2    Schiffers, P.3    Moens, A.4    Paul, M.5    Schmidt, H.H.6
  • 110
    • 3543107212 scopus 로고    scopus 로고
    • Fibrotic disease and the T(H)1/T(H)2 paradigm
    • doi:10.1038/nri1412
    • Wynn TA (2004) Fibrotic disease and the T(H)1/T(H)2 paradigm. Nat Rev Immunol 4(8):583-594. doi:10.1038/nri1412
    • (2004) Nat Rev Immunol , vol.4 , Issue.8 , pp. 583-594
    • Wynn, T.A.1
  • 111
    • 38549159026 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of fibrosis
    • doi:10.1002/path.2277
    • Wynn TA (2008) Cellular and molecular mechanisms of fibrosis. J Pathol 214(2):199-210. doi:10.1002/path.2277
    • (2008) J Pathol , vol.214 , Issue.2 , pp. 199-210
    • Wynn, T.A.1
  • 112
    • 84863702343 scopus 로고    scopus 로고
    • Mechanisms of fibrosis: Therapeutic translation for fibrotic disease
    • doi:10.1038/nm.2807
    • Wynn TA, Ramalingam TR (2012) Mechanisms of fibrosis: therapeutic translation for fibrotic disease. Nat Med 18(7):1028-1040. doi:10.1038/nm.2807
    • (2012) Nat Med , vol.18 , Issue.7 , pp. 1028-1040
    • Wynn, T.A.1    Ramalingam, T.R.2
  • 113
    • 52949093112 scopus 로고    scopus 로고
    • Resveratrol reduces endothelial progenitor cells senescence through augmentation of telomerase activity by Akt-dependent mechanisms
    • doi:10.1038/bjp.2008.272
    • Xia L, Wang XX, Hu XS, Guo XG, Shang YP, Chen HJ, Zeng CL, Zhang FR, Chen JZ (2008) Resveratrol reduces endothelial progenitor cells senescence through augmentation of telomerase activity by Akt-dependent mechanisms. Br J Pharmacol 155(3):387-394. doi:10.1038/bjp.2008.272
    • (2008) Br J Pharmacol , vol.155 , Issue.3 , pp. 387-394
    • Xia, L.1    Wang, X.X.2    Hu, X.S.3    Guo, X.G.4    Shang, Y.P.5    Chen, H.J.6    Zeng, C.L.7    Zhang, F.R.8    Chen, J.Z.9
  • 115
    • 31344468166 scopus 로고    scopus 로고
    • Experimental mouse model of scleroderma: Induction by bleomycin
    • Lawrence SC (ed) CRC Press, Boca Raton doi:10.1684/ejd.2008.0570
    • Yamamoto T (2004) Experimental mouse model of scleroderma: induction by bleomycin. In: Lawrence SC (ed) Animal models of human inflammatory skin diseases. CRC Press, Boca Raton, pp 535-547. doi:10.1684/ejd.2008.0570
    • (2004) Animal Models of Human Inflammatory Skin Diseases , pp. 535-547
    • Yamamoto, T.1
  • 116
    • 31344473454 scopus 로고    scopus 로고
    • The bleomycin-induced scleroderma model: What have we learned for scleroderma pathogenesis?
    • doi:10.1007/s00403-005-0635-z
    • Yamamoto T (2006) The bleomycin-induced scleroderma model: what have we learned for scleroderma pathogenesis? Arch Dermatol Res 297(8):333-344. doi:10.1007/s00403-005-0635-z
    • (2006) Arch Dermatol Res , vol.297 , Issue.8 , pp. 333-344
    • Yamamoto, T.1
  • 117
    • 60549096464 scopus 로고    scopus 로고
    • Scleroderma-pathophysiology
    • doi:10.1684/ejd 2008.0570
    • Yamamoto T (2009) Scleroderma-pathophysiology. Eur J Dermatol 19(1):14-24. doi:10.1684/ejd 2008.0570
    • (2009) Eur J Dermatol , vol.19 , Issue.1 , pp. 14-24
    • Yamamoto, T.1
  • 118
    • 79960380532 scopus 로고    scopus 로고
    • Autoimmune mechanisms of scleroderma and a role of oxidative stress
    • doi:10.4161/self.2.1.14058
    • Yamamoto T (2011) Autoimmune mechanisms of scleroderma and a role of oxidative stress. Self/Nonself 2(1):4-10. doi:10.4161/self.2.1.14058
    • (2011) Self/Nonself , vol.2 , Issue.1 , pp. 4-10
    • Yamamoto, T.1
  • 119
    • 0036150358 scopus 로고    scopus 로고
    • Animal model of sclerotic skin. V: Increased expression of alpha-smooth muscle actin in fibroblastic cells in bleomycin-induced scleroderma
    • doi:10.1006/clim 2001.5138
    • Yamamoto T, Nishioka K (2002) Animal model of sclerotic skin. V: increased expression of alpha-smooth muscle actin in fibroblastic cells in bleomycin-induced scleroderma. Clin Immunol 102(1):77-83. doi:10.1006/clim 2001.5138
    • (2002) Clin Immunol , vol.102 , Issue.1 , pp. 77-83
    • Yamamoto, T.1    Nishioka, K.2
  • 120
    • 0032706030 scopus 로고    scopus 로고
    • Effect of superoxide dismutase on bleomycin-induced dermal sclerosis: Implications for the treatment of systemic sclerosis
    • doi:10.1046/j.1523-1747.1999.00758.x
    • Yamamoto T, Takagawa S, Katayama I, Mizushima Y, Nishioka K (1999) Effect of superoxide dismutase on bleomycin-induced dermal sclerosis: implications for the treatment of systemic sclerosis. J Invest Dermatol 113(5):843-847. doi:10.1046/j.1523-1747.1999.00758.x
    • (1999) J Invest Dermatol , vol.113 , Issue.5 , pp. 843-847
    • Yamamoto, T.1    Takagawa, S.2    Katayama, I.3    Mizushima, Y.4    Nishioka, K.5
  • 121
    • 78349296702 scopus 로고    scopus 로고
    • Effects of pravastatin on murine chronic graft-versus-host disease
    • doi:10.1097/TP.0b013e3181f2c92b
    • Yoon HK, Lim JY, Kim TJ, Cho CS, Min CK (2010) Effects of pravastatin on murine chronic graft-versus-host disease. Transplantation 90(8):853-860. doi:10.1097/TP.0b013e3181f2c92b
    • (2010) Transplantation , vol.90 , Issue.8 , pp. 853-860
    • Yoon, H.K.1    Lim, J.Y.2    Kim, T.J.3    Cho, C.S.4    Min, C.K.5
  • 122
    • 80053495041 scopus 로고    scopus 로고
    • The specific free radical scavenger edaravone suppresses fibrosis in the ble-omycin- induced and tight skin mouse models of systemic sclerosis
    • doi:10.1002/art.30470
    • Yoshizaki A, Yanaba K, Ogawa A, Iwata Y, Ogawa F, Takenaka M, Shimizu K, Asano Y, Kadono T, Sato S (2011) The specific free radical scavenger edaravone suppresses fibrosis in the ble-omycin- induced and tight skin mouse models of systemic sclerosis. Arthr Rheum 63(10):3086-3097. doi:10.1002/art.30470
    • (2011) Arthr Rheum , vol.63 , Issue.10 , pp. 3086-3097
    • Yoshizaki, A.1    Yanaba, K.2    Ogawa, A.3    Iwata, Y.4    Ogawa, F.5    Takenaka, M.6    Shimizu, K.7    Asano, Y.8    Kadono, T.9    Sato, S.10
  • 123
    • 81855201314 scopus 로고    scopus 로고
    • Autosomal recessive LMNA mutation causing restrictive dermopathy
    • doi:10.1111/j.1399-0004.2010.01385.x
    • Youn GJ, Uzunyan M, Vachon L, Johnson J, Winder TL, Yano S (2010) Autosomal recessive LMNA mutation causing restrictive dermopathy. Clin Genet 78(2):199-200. doi:10.1111/j.1399-0004.2010.01385.x
    • (2010) Clin Genet , vol.78 , Issue.2 , pp. 199-200
    • Youn, G.J.1    Uzunyan, M.2    Vachon, L.3    Johnson, J.4    Winder, T.L.5    Yano, S.6
  • 124
    • 33749349202 scopus 로고    scopus 로고
    • Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice
    • DOI 10.2337/db05-1188
    • Zang M, Xu S, Maitland-Toolan KA, Zuccollo A, Hou X, Jiang B, Wierzbicki M, Verbeuren TJ, Cohen RA (2006) Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice. Diabetes 55(8):2180-2191. doi:10.2337/db05-1188 (Pubitemid 44743614)
    • (2006) Diabetes , vol.55 , Issue.8 , pp. 2180-2191
    • Zang, M.1    Xu, S.2    Maitland-Toolan, K.A.3    Zuccollo, A.4    Hou, X.5    Jiang, B.6    Wierzbicki, M.7    Verbeuren, T.J.8    Cohen, R.A.9
  • 125
    • 33751100885 scopus 로고    scopus 로고
    • Green tea extract and (-)-epigallocatechin-3-gallate inhibit mast cell-stimulated type I collagen expression in keloid fibroblasts via blocking PI-3K/Akt signaling pathways
    • DOI 10.1038/sj.jid.5700472, PII 5700472
    • Zhang Q, Kelly AP, Wang L, French SW, Tang X, Duong HS, Messadi DV, Le AD (2006) Green tea extract and (-)-epi-gallocatechin- 3-gallate inhibit mast cell-stimulated type I collagen expression in keloid fibroblasts via blocking PI-3 K/AkT signaling pathways. J Invest Dermatol 126(12):2607-2613. doi:10.1038/sj.jid.5700472 (Pubitemid 44764044)
    • (2006) Journal of Investigative Dermatology , vol.126 , Issue.12 , pp. 2607-2613
    • Zhang, Q.1    Kelly, A.P.2    Wang, L.3    French, S.W.4    Tang, X.5    Duong, H.S.6    Messadi, D.V.7    Le, A.D.8
  • 126
    • 34548131200 scopus 로고    scopus 로고
    • Review of the female Duroc/Yorkshire pig model of human fibroproliferative scarring
    • DOI 10.1111/j.1524-475X.2007.00223.x
    • Zhu KQ, Carrougher GJ, Gibran NS, Isik FF, Engrav LH (2007) Review of the female Duroc/Yorkshire pig model of human fibroproliferative scarring. Wound Repair Regen Off Publ Wound Healing Soc Eur Tissue Repair Soc 15(Suppl 1):S32-39. doi:10.1111/j.1524-475X.2007.00223.x (Pubitemid 47301672)
    • (2007) Wound Repair and Regeneration , vol.15 , Issue.SUPPL. 1
    • Zhu, K.Q.1    Carrougher, G.J.2    Gibran, N.S.3    Isik, F.F.4    Engrav, L.H.5
  • 127
    • 0035960336 scopus 로고    scopus 로고
    • Regulation of glutathione redox status in lung and liver by conditioning regimens and keratinocyte growth factor in murine allogeneic bone marrow transplantation
    • Ziegler TR, Panoskaltsus-Mortari A, Gu LH, Jonas CR, Farrell CL, Lacey DL, Jones DP, Blazar BR (2001) Regulation of glutathione redox status in lung and liver by conditioning regimens and keratinocyte growth factor in murine allogeneic bone marrow transplantation. Transplantation 72(8):1354-1362 (Pubitemid 33015758)
    • (2001) Transplantation , vol.72 , Issue.8 , pp. 1354-1362
    • Ziegler, T.R.1    Panoskaltsus-Mortari, A.2    Gu, L.H.3    Jonas, C.R.4    Farrell, C.L.5    Lacey, D.L.6    Jones, D.P.7    Blazar, B.R.8


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