Resveratrol reduces endothelial progenitor cells senescence through augmentation of telomerase activity by Akt-dependent mechanisms

British Journal of Pharmacology

Volumn 155, Issue 3, 2008, Pages 387-394

  Xia, L ^a   Wang, X X ^a   Hu, X S ^a   Guo, X G ^a   Shang, Y P ^a   Chen, H J ^a   Zeng, C L ^a   Zhang, F R ^a   Chen, J Z ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Akt; Endothelial progenitor cells; Resveratrol; Senescence; Telomerase

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BETA GALACTOSIDASE; BROXURIDINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FULVESTRANT; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RESVERATROL; TELOMERASE;

ADULT; ARTICLE; ASSAY; BOYDEN CHAMBER ASSAY; BROMODEOXYURIDINE INCORPORATION ASSAY; CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; MALE; NORMAL HUMAN; PRIORITY JOURNAL; SENESCENCE; STEM CELL; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADULT; BLOTTING, WESTERN; CARDIOTONIC AGENTS; CELL AGING; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; FEMALE; HUMANS; MALE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STEM CELLS; STILBENES; TELOMERASE;

EID: 52949093112     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/bjp.2008.272     Document Type: Article

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