Epigallocatechin-3-gallate (EGCG) reduces liver inflammation, oxidative stress and fibrosis in carbon tetrachloride (CCl4)-induced liver injury in mice

Toxicology

Volumn 273, Issue 1-3, 2010, Pages 45-52

  Tipoe, George L ^a   Leung, Tung Ming ^a,b   Liong, Emily C ^a   Lau, Thomas Yue Huen ^c   Fung, Man Lung ^a   Nanji, Amin A ^b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b DALHOUSIE UNIVERSITY   (Canada)

^c HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

Carbon tetrachloride (CCl4); Epigallocatechin 3 gallate (EGCG); Liver fibrosis; Liver inflammation; Oxidative stress

Indexed keywords

3 NITROTYROSINE; ALPHA SMOOTH MUSCLE ACTIN; CARBON TETRACHLORIDE; CCAAT ENHANCER BINDING PROTEIN; CYCLOOXYGENASE 2; EPIGALLOCATECHIN GALLATE; GELATINASE A; GELATINASE B; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; PROCOLLAGEN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; 3-NITROTYROSINE; ACTIN; ALPHA SMOOTH MUSCLE ACTIN, MOUSE; ALPHA-SMOOTH MUSCLE ACTIN, MOUSE; ANTIINFLAMMATORY AGENT; CATECHIN; COLLAGEN TYPE 1; CYCLOOXYGENASE 2 INHIBITOR; DRUG DERIVATIVE; MATRIX METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE; TYROSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CHRONIC TOXICITY; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; ENZYME ACTIVITY; HEPATITIS; HISTOPATHOLOGY; LIVER FIBROSIS; LIVER INJURY; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; C57BL MOUSE; DRUG EFFECT; LIVER CIRRHOSIS; METABOLISM; TOXIC HEPATITIS;

MUS;

ACTINS; ANIMALS; ANTI-INFLAMMATORY AGENTS; CARBON TETRACHLORIDE; CATECHIN; COLLAGEN TYPE I; CYCLOOXYGENASE 2 INHIBITORS; DRUG-INDUCED LIVER INJURY; LIVER CIRRHOSIS; MALE; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED C57BL; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; TISSUE INHIBITOR OF METALLOPROTEINASES; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE;

EID: 77953279213     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2010.04.014     Document Type: Article

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