-
1
-
-
0033819621
-
Collagens: Building blocks at the end of the development time
-
Byers PH. Collagens: building blocks at the end of the development time. Clin Genet 2000 58: 270 279.
-
(2000)
Clin Genet
, vol.58
, pp. 270-279
-
-
Byers, P.H.1
-
2
-
-
0027291184
-
Ehlers-Danlos syndrome type VIIB. Morphology of type i collagen fibrils formed in vivo and in vitro is determined by the conformation of the retained N-propeptide
-
Holmes DF, Watson RB, Steinmann B, Kadler KE. Ehlers-Danlos syndrome type VIIB. Morphology of type I collagen fibrils formed in vivo and in vitro is determined by the conformation of the retained N-propeptide. J Biol Chem 1993 268: 15758 15765.
-
(1993)
J Biol Chem
, vol.268
, pp. 15758-15765
-
-
Holmes, D.F.1
Watson, R.B.2
Steinmann, B.3
Kadler, K.E.4
-
3
-
-
0033753486
-
Regulation of matrix biosynthesis and degradation in systemic sclerosis
-
Widom RL. Regulation of matrix biosynthesis and degradation in systemic sclerosis. Curr Opin Rheumatol 2000 12: 534 539.
-
(2000)
Curr Opin Rheumatol
, vol.12
, pp. 534-539
-
-
Widom, R.L.1
-
4
-
-
0034541434
-
Cytokine modulation of extracellular matrix gene expression: Relevance to fibrotic skin diseases
-
Uitto J, Kouba D. Cytokine modulation of extracellular matrix gene expression: relevance to fibrotic skin diseases. J Dermatol Sci 2001 24: S60 S69.
-
(2001)
J Dermatol Sci
, vol.24
-
-
Uitto, J.1
Kouba, D.2
-
5
-
-
0036586090
-
Factors Involved in the Regulation of Type i Collagen Gene Expression: Implication in Fibrosis
-
Ghosh AK. Factors Involved in the Regulation of Type I Collagen Gene Expression: implication in Fibrosis. Exp Biol Med 2002 227: 301 314.
-
(2002)
Exp Biol Med
, vol.227
, pp. 301-314
-
-
Ghosh, A.K.1
-
6
-
-
0036448477
-
The role of TGF-β signaling in the pathogenesis of fibrosis in scleroderma
-
Ihn H. The role of TGF-β signaling in the pathogenesis of fibrosis in scleroderma. Arch Immunol Ther Exp 2002 50: 325 331.
-
(2002)
Arch Immunol Ther Exp
, vol.50
, pp. 325-331
-
-
Ihn, H.1
-
7
-
-
65849445411
-
Connective tissue growth factor: Growth factor, matricellular organizer, fibrotic biomarker or molecular target for anti-fibrotic therapy in SSc?
-
Abraham D. Connective tissue growth factor: growth factor, matricellular organizer, fibrotic biomarker or molecular target for anti-fibrotic therapy in SSc? Rheumatology 2008 47: v8 v9.
-
(2008)
Rheumatology
, vol.47
-
-
Abraham, D.1
-
8
-
-
0024322543
-
Differential regulation of collagen, glycosaminoglycan, fibronectin and collagenase activity production in cultured human adult dermal fibroblasts by interleukin 1α and β and tumor necrosis factor-α and β
-
Duncun MR, Berman B. Differential regulation of collagen, glycosaminoglycan, fibronectin and collagenase activity production in cultured human adult dermal fibroblasts by interleukin 1α and β and tumor necrosis factor-α and β. J Invest Dermatol 1989 92: 699 706.
-
(1989)
J Invest Dermatol
, vol.92
, pp. 699-706
-
-
Duncun, M.R.1
Berman, B.2
-
9
-
-
0026446005
-
Human fibroblasts synthesize elevated levels of extracellular matrix protein in response to interleukin 4
-
Postlethwaite AE, Holness MA, Katai H, Raghow R. Human fibroblasts synthesize elevated levels of extracellular matrix protein in response to interleukin 4. J Clin Invest 1992 90: 1479 1485.
-
(1992)
J Clin Invest
, vol.90
, pp. 1479-1485
-
-
Postlethwaite, A.E.1
Holness, M.A.2
Katai, H.3
Raghow, R.4
-
10
-
-
0017280107
-
Platelet factors stimulate fibroblasts and smooth muscle cells quiescent in plasma serum to proliferate
-
Rutherford RB, Ross R. Platelet factors stimulate fibroblasts and smooth muscle cells quiescent in plasma serum to proliferate. J Cell Biol 1976 69: 196 203.
-
(1976)
J Cell Biol
, vol.69
, pp. 196-203
-
-
Rutherford, R.B.1
Ross, R.2
-
11
-
-
0000686740
-
Human epidermal growth factor: Isolation and chemical and biological properties
-
Cohen P, Carpenter G. Human epidermal growth factor: isolation and chemical and biological properties. Proc Natl Acad Sci USA 1975 72: 1317 1321.
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, pp. 1317-1321
-
-
Cohen, P.1
Carpenter, G.2
-
13
-
-
0035178406
-
Role of protein kinase C-δ in the regulation of collagen gene expression in scleroderma fibroblasts
-
Jimenez SA, Gaidarova S, Saitta B et al. Role of protein kinase C-δ in the regulation of collagen gene expression in scleroderma fibroblasts. J Clin Invest 2001 108: 1395 1403.
-
(2001)
J Clin Invest
, vol.108
, pp. 1395-1403
-
-
Jimenez, S.A.1
Gaidarova, S.2
Saitta, B.3
-
14
-
-
0024887547
-
Immunologic aspects of scleroderma
-
Korn JH. Immunologic aspects of scleroderma. Curr Opin Rheumatol 1989 1: 479 484.
-
(1989)
Curr Opin Rheumatol
, vol.1
, pp. 479-484
-
-
Korn, J.H.1
-
15
-
-
0025210095
-
Fibroblast-matrix interactions and their role in the pathogenesis of fibrosis
-
Mauch C, Krieg T. Fibroblast-matrix interactions and their role in the pathogenesis of fibrosis. Rheum Dis Clin North Am 1990 16: 93 107.
-
(1990)
Rheum Dis Clin North Am
, vol.16
, pp. 93-107
-
-
Mauch, C.1
Krieg, T.2
-
16
-
-
0026955930
-
Altered regulation of collagen metabolism in scleroderma fibroblasts grown within three-dimensional collagen gels
-
Mauch C, Kozlowska E, Eckes B, Krieg T. Altered regulation of collagen metabolism in scleroderma fibroblasts grown within three-dimensional collagen gels. Exp Dermatol 1992 1: 185 190.
-
(1992)
Exp Dermatol
, vol.1
, pp. 185-190
-
-
Mauch, C.1
Kozlowska, E.2
Eckes, B.3
Krieg, T.4
-
17
-
-
0029765057
-
Heterogeneity of collagen synthesis in normal and systemic sclerosis skin fibroblasts: Increased proportion of high collagen-producing cells in systemic sclerosis fibroblasts
-
Jelaska A, Arakawa M, Broketa G, Korn JH. Heterogeneity of collagen synthesis in normal and systemic sclerosis skin fibroblasts: increased proportion of high collagen-producing cells in systemic sclerosis fibroblasts. Arthritis Rheum 1996 39: 1338 1346.
-
(1996)
Arthritis Rheum
, vol.39
, pp. 1338-1346
-
-
Jelaska, A.1
Arakawa, M.2
Broketa, G.3
Korn, J.H.4
-
18
-
-
0023854176
-
Scleroderma (systemic sclerosis): Classification, subsets and pathogenesis
-
LeRoy EC, Black C, Fleischmajer R, Jablonska S, Krieg T, Medsger TA Jr. Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol 1988 15: 202 206.
-
(1988)
J Rheumatol
, vol.15
, pp. 202-206
-
-
Leroy, E.C.1
Black, C.2
Fleischmajer, R.3
Jablonska, S.4
Krieg, T.5
Medsger, Jr.T.A.6
-
19
-
-
0035068434
-
Collagens and collagen-related diseases
-
Myllyharju J, Kivirikko KI. Collagens and collagen-related diseases. Ann Med 2001 33: 7 21.
-
(2001)
Ann Med
, vol.33
, pp. 7-21
-
-
Myllyharju, J.1
Kivirikko, K.I.2
-
20
-
-
0032766255
-
Cloning of cDNA for rat pro α1(V) collagen mRNA. Expression patterns of type I, type III and type v collagen genes in experimental granulation tissue
-
Inkinen K, Turakainen H, Wolff H, Ahonen J. Cloning of cDNA for rat pro α1(V) collagen mRNA. Expression patterns of type I, type III and type V collagen genes in experimental granulation tissue. Connect Tissue Res 1999 40: 209 220.
-
(1999)
Connect Tissue Res
, vol.40
, pp. 209-220
-
-
Inkinen, K.1
Turakainen, H.2
Wolff, H.3
Ahonen, J.4
-
21
-
-
0036447070
-
Building collagen molecules, fibrils, and suprafibrillar structures
-
Hulmes DJ. Building collagen molecules, fibrils, and suprafibrillar structures. J Struct Biol 2002 137: 2 10.
-
(2002)
J Struct Biol
, vol.137
, pp. 2-10
-
-
Hulmes, D.J.1
-
22
-
-
0033934650
-
Serum markers of type i collagen synthesis and degradation in amyotrophic lateral sclerosis
-
Ono S, Imai T, Shimizu N, Nakayama M, Yamano T, Tsumura M. Serum markers of type I collagen synthesis and degradation in amyotrophic lateral sclerosis. Eur Neurol 2000 44: 49 56.
-
(2000)
Eur Neurol
, vol.44
, pp. 49-56
-
-
Ono, S.1
Imai, T.2
Shimizu, N.3
Nakayama, M.4
Yamano, T.5
Tsumura, M.6
-
25
-
-
0021969544
-
Regional chromosome mapping of human collagen genes α2 (I) and α1 (I) (COLIA2 and COLIA1)
-
Retief E, Parker MI, Retief AE. Regional chromosome mapping of human collagen genes α2 (I) and α1 (I) (COLIA2 and COLIA1). Hum Genet 1985 69: 304 308.
-
(1985)
Hum Genet
, vol.69
, pp. 304-308
-
-
Retief, E.1
Parker, M.I.2
Retief, A.E.3
-
26
-
-
0021215748
-
Human pro-α1 (I) collagen gene structure reveals evolutionary conservation of a pattern of introns and exons
-
Chu ML, de WetW, Bernard M et al. Human pro-α1 (I) collagen gene structure reveals evolutionary conservation of a pattern of introns and exons. Nature 1984 310: 337 340.
-
(1984)
Nature
, vol.310
, pp. 337-340
-
-
Chu, M.L.1
De Wet, W.2
Bernard, M.3
-
27
-
-
0021064358
-
The mRNAs for the pro-α1(I) and pro-α2(I) chains of Type i procollagen are translated at the same rate in normal human fibroblasts and in fibroblasts from two variants of osteogenesis imperfecta with altered steady-state ratios of the two mRNAs
-
de WetWJ, Chu ML, Prockop DJ. The mRNAs for the pro-α1(I) and pro-α2(I) chains of Type I procollagen are translated at the same rate in normal human fibroblasts and in fibroblasts from two variants of osteogenesis imperfecta with altered steady-state ratios of the two mRNAs. J Biol Chem 1983 258: 14385 14389.
-
(1983)
J Biol Chem
, vol.258
, pp. 14385-14389
-
-
De Wet, W.J.1
Chu, M.L.2
Prockop, D.J.3
-
28
-
-
0021989344
-
Fine structural analysis of the human pro-α1 (I) collagen gene. Promoter structure, AluI repeats, and polymorphic transcripts
-
Chu ML, de WetW, Bernard M, Ramirez F. Fine structural analysis of the human pro-α1 (I) collagen gene. Promoter structure, AluI repeats, and polymorphic transcripts. J Biol Chem 1985 260: 2315 2320.
-
(1985)
J Biol Chem
, vol.260
, pp. 2315-2320
-
-
Chu, M.L.1
De Wet, W.2
Bernard, M.3
Ramirez, F.4
-
29
-
-
0022431515
-
Analysis of the promoter region and the N-propeptide domain of the human pro α2(I) collagen gene
-
Dickson LA, de WetW, Di LibertoM, Weil D, Ramirez F. Analysis of the promoter region and the N-propeptide domain of the human pro α2(I) collagen gene. Nucleic Acids Res 1985 13: 3427 3438.
-
(1985)
Nucleic Acids Res
, vol.13
, pp. 3427-3438
-
-
Dickson, L.A.1
De Wet, W.2
Di, L.M.3
Weil, D.4
Ramirez, F.5
-
30
-
-
33645949405
-
Potential regulatory elements of the constitutive up-regulated α2(I) collagen gene in scleroderma dermal fibroblasts
-
Jinnin M, Ihn H, Mimura Y, Asano Y, Tamaki K. Potential regulatory elements of the constitutive up-regulated α2(I) collagen gene in scleroderma dermal fibroblasts. Biochem Biophys Res Commun 2006 343: 904 909.
-
(2006)
Biochem Biophys Res Commun
, vol.343
, pp. 904-909
-
-
Jinnin, M.1
Ihn, H.2
Mimura, Y.3
Asano, Y.4
Tamaki, K.5
-
31
-
-
0032921867
-
Stimulation of type i collagen transcription in human skin fibroblasts by TGF-β: Involvement of Smad 3
-
Chen SJ, Yuan W, Mori Y, Levenson A, Trojanowska M, Varga J. Stimulation of type I collagen transcription in human skin fibroblasts by TGF-β: involvement of Smad 3. J Invest Dermatol 1999 112: 49 57.
-
(1999)
J Invest Dermatol
, vol.112
, pp. 49-57
-
-
Chen, S.J.1
Yuan, W.2
Mori, Y.3
Levenson, A.4
Trojanowska, M.5
Varga, J.6
-
32
-
-
85047692249
-
Impaired Smad7-Smurf-mediated negative regulation of TGF-β signaling in scleroderma fibroblasts
-
Asano Y, Ihn H, Yamane K, Kubo M, Tamaki K. Impaired Smad7-Smurf-mediated negative regulation of TGF-β signaling in scleroderma fibroblasts. J Clin Invest 2004 113: 253 264.
-
(2004)
J Clin Invest
, vol.113
, pp. 253-264
-
-
Asano, Y.1
Ihn, H.2
Yamane, K.3
Kubo, M.4
Tamaki, K.5
-
33
-
-
0036086293
-
Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice
-
Zhao J, Shi W, Wang YL et al. Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice. Am J Physiol Lung Cell Mol Physiol 2002 282: L585 L593.
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.282
-
-
Zhao, J.1
Shi, W.2
Wang, Y.L.3
-
34
-
-
0037036387
-
Ets1 is an effector of the transforming growth factor β (TGF-β) signaling pathway and an antagonist of the profibrotic effects of TGF-β
-
Czuwara-Ladykowska J, Sementchenko VI, Watson DK, Trojanowska M. Ets1 is an effector of the transforming growth factor β (TGF-β) signaling pathway and an antagonist of the profibrotic effects of TGF-β. J Biol Chem 2002 277: 20399 20408.
-
(2002)
J Biol Chem
, vol.277
, pp. 20399-20408
-
-
Czuwara-Ladykowska, J.1
Sementchenko, V.I.2
Watson, D.K.3
Trojanowska, M.4
-
35
-
-
0033791928
-
Increased phosphorylation of transcription factor Sp1 in scleroderma fibroblasts: Association with increased expression of the type i collagen gene
-
Ihn H, Tamaki K. Increased phosphorylation of transcription factor Sp1 in scleroderma fibroblasts: association with increased expression of the type I collagen gene. Arthritis Rheum 2000 43: 2240 2247.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2240-2247
-
-
Ihn, H.1
Tamaki, K.2
-
36
-
-
0028956728
-
Characterization of a GC-rich region containing Sp1 binding site(s) as a constitutive responsive element of the α2(I) collagen gene in human fibroblasts
-
Tamaki T, Ohnishi K, Hartl C, LeRoy EC, Trojanowska M. Characterization of a GC-rich region containing Sp1 binding site(s) as a constitutive responsive element of the α2(I) collagen gene in human fibroblasts. J Biol Chem 1995 270: 4299 4304.
-
(1995)
J Biol Chem
, vol.270
, pp. 4299-4304
-
-
Tamaki, T.1
Ohnishi, K.2
Hartl, C.3
Leroy, E.C.4
Trojanowska, M.5
-
37
-
-
0035877684
-
Fli-1 inhibits collagen type i production in dermal fibroblasts via an Sp1-dependent pathway
-
Czuwara-Ladykowska J, Shirasaki F, Jackers P, Watson DK, Trojanowska M. Fli-1 inhibits collagen type I production in dermal fibroblasts via an Sp1-dependent pathway. J Biol Chem 2001 276: 20839 20848.
-
(2001)
J Biol Chem
, vol.276
, pp. 20839-20848
-
-
Czuwara-Ladykowska, J.1
Shirasaki, F.2
Jackers, P.3
Watson, D.K.4
Trojanowska, M.5
-
38
-
-
58249111616
-
Transcription factor Fli1 regulates collagen fibrillogenesis in mouse skin
-
Asano Y, Markiewicz M, Kubo M, Szalai G, Watson DK, Trojanowska M. Transcription factor Fli1 regulates collagen fibrillogenesis in mouse skin. Mol Cell Biol 2009 29: 425 434.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 425-434
-
-
Asano, Y.1
Markiewicz, M.2
Kubo, M.3
Szalai, G.4
Watson, D.K.5
Trojanowska, M.6
-
39
-
-
0037449713
-
Characterization of the c-Myb-responsive region and regulation of the human type i collagen α2 chain gene by c-Myb
-
Luchetti MM, Paroncini P, Majlingovà P et al. Characterization of the c-Myb-responsive region and regulation of the human type I collagen α2 chain gene by c-Myb. J Biol Chem 2003 278: 1533 1541.
-
(2003)
J Biol Chem
, vol.278
, pp. 1533-1541
-
-
Luchetti, M.M.1
Paroncini, P.2
Majlingovà, P.3
-
40
-
-
0032919323
-
C-myb, but not B-myb, upregulates type i collagen gene expression in human fibroblasts
-
Piccinini G, Golay J, Flora A et al. C-myb, but not B-myb, upregulates type I collagen gene expression in human fibroblasts. J Invest Dermatol 1999 112: 191 196.
-
(1999)
J Invest Dermatol
, vol.112
, pp. 191-196
-
-
Piccinini, G.1
Golay, J.2
Flora, A.3
-
41
-
-
0023808118
-
Elevated expression of c-myc proto-oncogene in scleroderma fibroblasts
-
Trojanowska M, Wu LT, LeRoy EC. Elevated expression of c-myc proto-oncogene in scleroderma fibroblasts. Oncogene 1988 3: 477 481.
-
(1988)
Oncogene
, vol.3
, pp. 477-481
-
-
Trojanowska, M.1
Wu, L.T.2
Leroy, E.C.3
-
42
-
-
0026063524
-
Transcriptional suppression of cellular gene expression by c-Myc
-
Yang BS, Geddes TJ, Pogulis RJ, de CrombruggheB, Freytag SO. Transcriptional suppression of cellular gene expression by c-Myc. Mol Cell Biol 1991 11: 2291 2295.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 2291-2295
-
-
Yang, B.S.1
Geddes, T.J.2
Pogulis, R.J.3
De Crombrugghe, B.4
Freytag, S.O.5
-
43
-
-
0030625679
-
The multifunctional role of the co-activator CBP in transcriptional regulation
-
Goldman PS, Tran VK, Goodman RH. The multifunctional role of the co-activator CBP in transcriptional regulation. Recent Prog Horm Res 1997 52: 103 119.
-
(1997)
Recent Prog Horm Res
, vol.52
, pp. 103-119
-
-
Goldman, P.S.1
Tran, V.K.2
Goodman, R.H.3
-
45
-
-
0032528236
-
The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-β-induced transcriptional activation
-
Feng XH, Zhang Y, Wu RY, Derynck R. The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-β-induced transcriptional activation. Genes Dev 1998 12: 2153 2163.
-
(1998)
Genes Dev
, vol.12
, pp. 2153-2163
-
-
Feng, X.H.1
Zhang, Y.2
Wu, R.Y.3
Derynck, R.4
-
46
-
-
0032527756
-
TGF-β-stimulated cooperation of Smad proteins with the coactivators CBP/p300
-
Janknecht R, Wells NJ, Hunter T. TGF-β-stimulated cooperation of Smad proteins with the coactivators CBP/p300. Genes Dev 1998 12: 2114 2119.
-
(1998)
Genes Dev
, vol.12
, pp. 2114-2119
-
-
Janknecht, R.1
Wells, N.J.2
Hunter, T.3
-
47
-
-
0031773264
-
TGF-β-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein
-
Shen X, Hu PP, Liberati NT, Datto MB, Frederick JP, Wang XF. TGF-β-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein. Mol Biol Cell 1998 9: 3309 3319.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 3309-3319
-
-
Shen, X.1
Hu, P.P.2
Liberati, N.T.3
Datto, M.B.4
Frederick, J.P.5
Wang, X.F.6
-
48
-
-
0032080848
-
The SAGA unfolds: Convergence of transcription regulators in chromatin-modifying complexes
-
Grant PA, Sterner DE, Duggan LJ, Workman JL, Berger SL. The SAGA unfolds: convergence of transcription regulators in chromatin-modifying complexes. Trends Cell Biol 1998 8: 193 197.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 193-197
-
-
Grant, P.A.1
Sterner, D.E.2
Duggan, L.J.3
Workman, J.L.4
Berger, S.L.5
-
49
-
-
0034691764
-
Smad-dependent stimulation of type i collagen gene expression in human skin fibroblasts by TGF-β involves functional cooperation with p300/CBP transcriptional coactivators
-
Ghosh AK, Yuan W, Mori Y, Varga J. Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-β involves functional cooperation with p300/CBP transcriptional coactivators. Oncogene 2000 19: 3546 3555.
-
(2000)
Oncogene
, vol.19
, pp. 3546-3555
-
-
Ghosh, A.K.1
Yuan, W.2
Mori, Y.3
Varga, J.4
-
50
-
-
1842643616
-
Transcrptional coactivators p300/CBP and Type i collagen gene expression
-
Ghosh AK, Varga J. Transcrptional coactivators p300/CBP and Type I collagen gene expression. Curr Sci 2003 85: 155 161.
-
(2003)
Curr Sci
, vol.85
, pp. 155-161
-
-
Ghosh, A.K.1
Varga, J.2
-
51
-
-
17244371148
-
Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor β
-
Bhattacharyya S, Ghosh AK, Pannu J et al. Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor β. Arthritis Rheum 2005 52: 1248 1258.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1248-1258
-
-
Bhattacharyya, S.1
Ghosh, A.K.2
Pannu, J.3
-
52
-
-
31544442502
-
Constitutively phosphorylated Smad3 interacts with Sp1 and p300 in scleroderma fibroblasts
-
Ihn H, Yamane K, Asano Y, Jinnin M, Tamaki K. Constitutively phosphorylated Smad3 interacts with Sp1 and p300 in scleroderma fibroblasts. Rheumatology 2006 45: 157 165.
-
(2006)
Rheumatology
, vol.45
, pp. 157-165
-
-
Ihn, H.1
Yamane, K.2
Asano, Y.3
Jinnin, M.4
Tamaki, K.5
-
53
-
-
0033607240
-
SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor b signaling
-
Sun Y, Liu X, Ng-Eaton E, Lodish HF, Weinberg RA. SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor b signaling. Proc Natl Acad Sci USA 1999 96: 12442 12447.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12442-12447
-
-
Sun, Y.1
Liu, X.2
Ng-Eaton, E.3
Lodish, H.F.4
Weinberg, R.A.5
-
54
-
-
0033521032
-
C-Ski acts as a transcriptional co-repressor in transforming growth factor-β signaling through interaction with Smads
-
Akiyoshi S, Inoue H, Hanai J et al. c-Ski acts as a transcriptional co-repressor in transforming growth factor-β signaling through interaction with Smads. J Biol Chem 1999 274: 35269 35277.
-
(1999)
J Biol Chem
, vol.274
, pp. 35269-35277
-
-
Akiyoshi, S.1
Inoue, H.2
Hanai, J.3
-
55
-
-
34248548638
-
Involvement of the constitutive complex formation of c-Ski/SnoN with Smads in the impaired negative feedback regulation of transforming growth factor β signaling in scleroderma fibroblasts
-
Jinnin M, Ihn H, Mimura Y, Asano Y, Tamaki K. Involvement of the constitutive complex formation of c-Ski/SnoN with Smads in the impaired negative feedback regulation of transforming growth factor β signaling in scleroderma fibroblasts. Arthritis Rheum 2007 56: 1694 1705.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1694-1705
-
-
Jinnin, M.1
Ihn, H.2
Mimura, Y.3
Asano, Y.4
Tamaki, K.5
-
56
-
-
37349113805
-
Autocrine TGF-β signaling in the pathogenesis of systemic sclerosis
-
Ihn H. Autocrine TGF-β signaling in the pathogenesis of systemic sclerosis. J Dermatol Sci 2008 49: 103 113.
-
(2008)
J Dermatol Sci
, vol.49
, pp. 103-113
-
-
Ihn, H.1
-
57
-
-
75649122669
-
Matrix metalloproteinases
-
In. Genazzani, A.R. ed. London, UK. Informa Health Care
-
McDonnell S, O'Connor A, Murray D, Lynch CC. Matrix metalloproteinases. In: Genazzani AR ed. Hormone Replacement Therapy and Cancer: The Current Status of Research and Practice. London, UK: Informa Health Care, 2002 17 24.
-
(2002)
Hormone Replacement Therapy and Cancer: The Current Status of Research and Practice
, pp. 17-24
-
-
McDonnell, S.1
O'Connor, A.2
Murray, D.3
Lynch, C.C.4
-
58
-
-
0035188727
-
How matrix metalloproteinases regulate cell behavior
-
Sternlicht MD, Werb Z. How matrix metalloproteinases regulate cell behavior. Annu Rev Cell Dev Biol 2001 17: 463 516.
-
(2001)
Annu Rev Cell Dev Biol
, vol.17
, pp. 463-516
-
-
Sternlicht, M.D.1
Werb, Z.2
-
59
-
-
0027692326
-
Role of cytokines and inflammatory mediators in tissue destruction
-
Birkedal-Hansen H. Role of cytokines and inflammatory mediators in tissue destruction. J Periodontal Res 1993 28: 500 510.
-
(1993)
J Periodontal Res
, vol.28
, pp. 500-510
-
-
Birkedal-Hansen, H.1
-
60
-
-
0142212329
-
Regulation of matrix metalloproteinases: An overview
-
Chakraborti S, Mandal M, Das S, Mandal A, Chakraborti T. Regulation of matrix metalloproteinases: an overview. Mol Cell Biochem 2003 253: 269 285.
-
(2003)
Mol Cell Biochem
, vol.253
, pp. 269-285
-
-
Chakraborti, S.1
Mandal, M.2
Das, S.3
Mandal, A.4
Chakraborti, T.5
-
62
-
-
0035479845
-
Matrix metalloproteinases: They're not just for matrix anymore
-
Oct
-
McCawley LJ, Matrisian LM. Matrix metalloproteinases: they're not just for matrix anymore Curr Opin Cell Biol 2001 (Oct 13 (5 534 540.
-
(2001)
Curr Opin Cell Biol
, vol.13
, Issue.5
, pp. 534-540
-
-
McCawley, L.J.1
Matrisian, L.M.2
-
63
-
-
36148941000
-
Myeloperoxidase inactivates TIMP-1 by oxidizing its N-terminal cysteine residue: An oxidative mechanism for regulating proteolysis during inflammation
-
Wang Y, Rosen H, Madtes DK et al. Myeloperoxidase inactivates TIMP-1 by oxidizing its N-terminal cysteine residue: an oxidative mechanism for regulating proteolysis during inflammation. J Biol Chem 2007 282: 31826 31834.
-
(2007)
J Biol Chem
, vol.282
, pp. 31826-31834
-
-
Wang, Y.1
Rosen, H.2
Madtes, D.K.3
-
65
-
-
0033036230
-
Clinical usefulness of serum tissue inhibitor of metalloproteinases (TIMP)-2 assay in patients with chronic liver disease in comparison with serum TIMP-1
-
Murawaki Y, Ikuta Y, Kawasaki H. Clinical usefulness of serum tissue inhibitor of metalloproteinases (TIMP)-2 assay in patients with chronic liver disease in comparison with serum TIMP-1. Clin Chim Acta 1999 281: 109 120.
-
(1999)
Clin Chim Acta
, vol.281
, pp. 109-120
-
-
Murawaki, Y.1
Ikuta, Y.2
Kawasaki, H.3
-
66
-
-
0031026874
-
Matrix metalloproteinases
-
Parsons SL, Watoson SA, Brown PD, Collins HM, Steele RJC. Matrix metalloproteinases. Br J Surg 1997 84: 160 166.
-
(1997)
Br J Surg
, vol.84
, pp. 160-166
-
-
Parsons, S.L.1
Watoson, S.A.2
Brown, P.D.3
Collins, H.M.4
Steele, R.J.C.5
-
67
-
-
0030717692
-
Tissue inhibitors of metalloproteinases: Structure, regulation and biological functions
-
Gomez DE, Alonso DF, Yoshiji H, Thorgeirsson UP. Tissue inhibitors of metalloproteinases: structure, regulation and biological functions. Eur J Cell Biol 1997 74: 111 122.
-
(1997)
Eur J Cell Biol
, vol.74
, pp. 111-122
-
-
Gomez, D.E.1
Alonso, D.F.2
Yoshiji, H.3
Thorgeirsson, U.P.4
-
68
-
-
2342433268
-
Fistulising Crohn's disease: MMPs gone away
-
Schuppan D, Freitag T. Fistulising Crohn's disease: MMPs gone away. Gut 2004 53: 622 624.
-
(2004)
Gut
, vol.53
, pp. 622-624
-
-
Schuppan, D.1
Freitag, T.2
-
70
-
-
0030668134
-
Gene expression of types i and III collagen, decorin, matrix metalloproteinases and tissue inhibitors of metalloproteinases in skin fibroblasts from patients with systemic sclerosis
-
Kuroda K, Shinkai H. Gene expression of types I and III collagen, decorin, matrix metalloproteinases and tissue inhibitors of metalloproteinases in skin fibroblasts from patients with systemic sclerosis. Arch Dermatol Res 1997 289: 567 572.
-
(1997)
Arch Dermatol Res
, vol.289
, pp. 567-572
-
-
Kuroda, K.1
Shinkai, H.2
-
71
-
-
0034890197
-
Serum TIMP-1, TIMP-2, and MMP-1 in patients with systemic sclerosis, primary Raynaud's phenomenon, and in normal controls
-
Young-Min SA, Beeton C, Laughton R et al. Serum TIMP-1, TIMP-2, and MMP-1 in patients with systemic sclerosis, primary Raynaud's phenomenon, and in normal controls. Ann Rheum Dis 2001 60: 846 851.
-
(2001)
Ann Rheum Dis
, vol.60
, pp. 846-851
-
-
Young-Min, S.A.1
Beeton, C.2
Laughton, R.3
-
72
-
-
0037379343
-
Function blocking autoantibodies against matrix metalloproteinase-1 in patients with systemic sclerosis
-
Sato S, Hayakawa I, Hasegawa M, Fujimoto M, Takehara K. Function blocking autoantibodies against matrix metalloproteinase-1 in patients with systemic sclerosis. J Invest Dermatol 2003 120: 542 547.
-
(2003)
J Invest Dermatol
, vol.120
, pp. 542-547
-
-
Sato, S.1
Hayakawa, I.2
Hasegawa, M.3
Fujimoto, M.4
Takehara, K.5
-
73
-
-
8144228787
-
Autoantibody against matrix metalloproteinase-3 in patients with systemic sclerosis
-
Nishijima C, Hayakawa I, Matsushita T et al. Autoantibody against matrix metalloproteinase-3 in patients with systemic sclerosis. Clin Exp Immunol 2004 138: 357 363.
-
(2004)
Clin Exp Immunol
, vol.138
, pp. 357-363
-
-
Nishijima, C.1
Hayakawa, I.2
Matsushita, T.3
-
74
-
-
2142784516
-
MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover
-
Holmbeck K, Bianco P, Caterina J et al. MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover. Cell 1999 99: 81 92.
-
(1999)
Cell
, vol.99
, pp. 81-92
-
-
Holmbeck, K.1
Bianco, P.2
Caterina, J.3
-
75
-
-
0033858063
-
Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis
-
Arthur MJ. Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis. Am J Physiol Gastrointest Liver Physiol 2000 279: G245 G249.
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.279
-
-
Arthur, M.J.1
-
76
-
-
0033914211
-
Gene expression of interstitial collagenase in both progressive and recovery phase of rat liver fibrosis induced by carbon tetrachloride
-
Watanabe T, Niioka M, Hozawa S et al. Gene expression of interstitial collagenase in both progressive and recovery phase of rat liver fibrosis induced by carbon tetrachloride. J Hepatol 2000 33: 224 235.
-
(2000)
J Hepatol
, vol.33
, pp. 224-235
-
-
Watanabe, T.1
Niioka, M.2
Hozawa, S.3
-
77
-
-
36048952125
-
Inhibitory effects of matrix metalloproteinase inhibitor ONO-4817 on morphological alterations in chlorhexidine gluconate-induced peritoneal sclerosis rats
-
Ro Y, Hamada C, Inaba M, Io H, Kaneko K, Tomino Y. Inhibitory effects of matrix metalloproteinase inhibitor ONO-4817 on morphological alterations in chlorhexidine gluconate-induced peritoneal sclerosis rats. Nephrol Dial Transplant 2007 22: 2838 2848.
-
(2007)
Nephrol Dial Transplant
, vol.22
, pp. 2838-2848
-
-
Ro, Y.1
Hamada, C.2
Inaba, M.3
Io, H.4
Kaneko, K.5
Tomino, Y.6
-
78
-
-
0035800880
-
Matrix metalloproteinase inhibition after myocardial infarction: A new approach to prevent heart failure?
-
Creemers EE, Cleutjens JP, Smits JF, Daemen MJ. Matrix metalloproteinase inhibition after myocardial infarction: a new approach to prevent heart failure? Circ Res 2001 89: 201 210.
-
(2001)
Circ Res
, vol.89
, pp. 201-210
-
-
Creemers, E.E.1
Cleutjens, J.P.2
Smits, J.F.3
Daemen, M.J.4
-
79
-
-
0035069059
-
Inhibition of bleomycin-induced pulmonary fibrosis in mice by the matrix metalloproteinase inhibitor batimastat
-
Corbel M, Caulet-Maugendre S, Germain N, Molet S, Lagente V, Boichot E. Inhibition of bleomycin-induced pulmonary fibrosis in mice by the matrix metalloproteinase inhibitor batimastat. J Pathol 2001 193: 538 545.
-
(2001)
J Pathol
, vol.193
, pp. 538-545
-
-
Corbel, M.1
Caulet-Maugendre, S.2
Germain, N.3
Molet, S.4
Lagente, V.5
Boichot, E.6
-
80
-
-
1342279516
-
An introduction to matrikines: Extracellular matrix-derived peptides which regulate cell activity. Implication in tumor invasion
-
Maquart FX, Pasco S, Ramont L, Hornebeck W, Monboisse JC. An introduction to matrikines: extracellular matrix-derived peptides which regulate cell activity. Implication in tumor invasion. Crit Rev Oncol Hematol 2004 49: 199 202.
-
(2004)
Crit Rev Oncol Hematol
, vol.49
, pp. 199-202
-
-
Maquart, F.X.1
Pasco, S.2
Ramont, L.3
Hornebeck, W.4
Monboisse, J.C.5
-
81
-
-
0028485654
-
Processing of tumour necrosis factor-α precursor by metalloproteinases
-
Gearing AJH, Beckett P, Christodoulou M et al. Processing of tumour necrosis factor-α precursor by metalloproteinases. Nature 1994 370: 555 557.
-
(1994)
Nature
, vol.370
, pp. 555-557
-
-
Gearing, A.J.H.1
Beckett, P.2
Christodoulou, M.3
-
82
-
-
0032194115
-
Generation of biologically active IL-1β by matrix metalloproteinases: A novel caspase-1-independent pathway of IL-1β processing
-
Schonbeck U, Mach F, Libby P. Generation of biologically active IL-1β by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1β processing. J Immunol 1998 161: 3340 3346.
-
(1998)
J Immunol
, vol.161
, pp. 3340-3346
-
-
Schonbeck, U.1
MacH, F.2
Libby, P.3
-
83
-
-
0024338065
-
Collagen synthesis by human fibroblasts: Regulation by transforming growth factor-β in the presence of other inflammatory mediators
-
Narayanan AS, Page RC, Swanson J. Collagen synthesis by human fibroblasts: regulation by transforming growth factor-β in the presence of other inflammatory mediators. Biochem J 1989 260: 463 469.
-
(1989)
Biochem J
, vol.260
, pp. 463-469
-
-
Narayanan, A.S.1
Page, R.C.2
Swanson, J.3
-
84
-
-
0028152937
-
Transforming growth factor β: The good, the bad, and the ugly
-
Wahl SM. Transforming growth factor β: the good, the bad, and the ugly. J Exp Med 1994 180: 1587 1590.
-
(1994)
J Exp Med
, vol.180
, pp. 1587-1590
-
-
Wahl, S.M.1
-
85
-
-
0031685620
-
TGF-β signal tansduction
-
Massague J. TGF-β signal tansduction. Ann Rev Biochem 1998 67: 753 791.
-
(1998)
Ann Rev Biochem
, vol.67
, pp. 753-791
-
-
Massague, J.1
-
86
-
-
0025215307
-
Mechanism of activation of latent recombinant transforming growth factor-β1 by plasmin
-
Lyons RM, Gentry LE, Purchio AF, Moses HL. Mechanism of activation of latent recombinant transforming growth factor-β1 by plasmin. J Cell Biol 1990 110: 1361 1367.
-
(1990)
J Cell Biol
, vol.110
, pp. 1361-1367
-
-
Lyons, R.M.1
Gentry, L.E.2
Purchio, A.F.3
Moses, H.L.4
-
87
-
-
33144458448
-
Increased expression of integrin αvβ5 induces the myofibroblastic differentiation of dermal fibroblasts
-
Asano Y, Ihn H, Yamane K, Jinnin M, Tamaki K. Increased expression of integrin αvβ5 induces the myofibroblastic differentiation of dermal fibroblasts. Am J Pathol 2006 168: 499 510.
-
(2006)
Am J Pathol
, vol.168
, pp. 499-510
-
-
Asano, Y.1
Ihn, H.2
Yamane, K.3
Jinnin, M.4
Tamaki, K.5
-
88
-
-
0027305971
-
Thrombospondin causes activation of latent transforming growth factor-β secreted by endothelial cells by a novel mechanism
-
Schultz-Cherry S, Murphy-Ullrich JE. Thrombospondin causes activation of latent transforming growth factor-β secreted by endothelial cells by a novel mechanism. J Cell Biol 1993 122: 923 932.
-
(1993)
J Cell Biol
, vol.122
, pp. 923-932
-
-
Schultz-Cherry, S.1
Murphy-Ullrich, J.E.2
-
89
-
-
0034109215
-
Activation of latent TGF-β by thrombospondin-1: Mechanisms and physiology
-
Murphy-Ullrich JE, Poczatek M. Activation of latent TGF-β by thrombospondin-1: mechanisms and physiology. Cytokine Growth Factor Rev 2000 11: 59 69.
-
(2000)
Cytokine Growth Factor Rev
, vol.11
, pp. 59-69
-
-
Murphy-Ullrich, J.E.1
Poczatek, M.2
-
90
-
-
0037192933
-
The integrin αvβ8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-β1
-
Mu D, Cambier S, Fjellbirkeland L et al. The integrin αvβ8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-β1. J Cell Biol 2002 157: 493 507.
-
(2002)
J Cell Biol
, vol.157
, pp. 493-507
-
-
Mu, D.1
Cambier, S.2
Fjellbirkeland, L.3
-
91
-
-
0028170226
-
Mechanism of activation of the TGF-β receptor
-
Wrana JL, Attisano L, Weisser R, Ventura F, Massague J. Mechanism of activation of the TGF-β receptor. Nature 1994 370: 341 347.
-
(1994)
Nature
, vol.370
, pp. 341-347
-
-
Wrana, J.L.1
Attisano, L.2
Weisser, R.3
Ventura, F.4
Massague, J.5
-
92
-
-
0032442852
-
Smads: Transcriptional activators of TGF-β responses
-
Derynck R, Zhang Y, Feng XH. Smads: transcriptional activators of TGF-β responses. Cell 1998 95: 737 740.
-
(1998)
Cell
, vol.95
, pp. 737-740
-
-
Derynck, R.1
Zhang, Y.2
Feng, X.H.3
-
93
-
-
14844353108
-
α2(I) collagen gene regulation by protein kinase C signaling in human dermal fibroblasts
-
Jinnin M, Ihn H, Yamane K, Mimura Y, Asano Y, Tamaki K. α2(I) collagen gene regulation by protein kinase C signaling in human dermal fibroblasts. Nucleic Acids Res 2005 33: 1337 1351.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 1337-1351
-
-
Jinnin, M.1
Ihn, H.2
Yamane, K.3
Mimura, Y.4
Asano, Y.5
Tamaki, K.6
-
94
-
-
0031587828
-
The MAD-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling
-
Hayashi H, Abdollah S, Qiu Y et al. The MAD-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling. Cell 1997 89: 1165 1173.
-
(1997)
Cell
, vol.89
, pp. 1165-1173
-
-
Hayashi, H.1
Abdollah, S.2
Qiu, Y.3
-
95
-
-
0030611757
-
Identification of Smad7, a TGF-β-inducible antagonist of TGF-β signalling
-
Nakao A, Afrakhte M, Moren A et al. Identification of Smad7, a TGF-β-inducible antagonist of TGF-β signalling. Nature 1997 389: 631 635.
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
Afrakhte, M.2
Moren, A.3
-
96
-
-
0034517389
-
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF-β receptor for degradation
-
Kavsak P, Rasmussen RK, Causing CG et al. Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF-β receptor for degradation. Mol Cell 2000 6: 1365 1375.
-
(2000)
Mol Cell
, vol.6
, pp. 1365-1375
-
-
Kavsak, P.1
Rasmussen, R.K.2
Causing, C.G.3
-
97
-
-
34447271736
-
Transforming growth factor-β and fibrosis
-
Verrecchia F, Mauviel A. Transforming growth factor-β and fibrosis. World J Gastroenterol 2007 13: 3056 3062.
-
(2007)
World J Gastroenterol
, vol.13
, pp. 3056-3062
-
-
Verrecchia, F.1
Mauviel, A.2
-
98
-
-
3543094383
-
Augmented production of transforming growth factor-β by cultured peripheral blood mononuclear cells from patients with systemic sclerosis
-
Hasegawa M, Sato S, Takehara K. Augmented production of transforming growth factor-β by cultured peripheral blood mononuclear cells from patients with systemic sclerosis. Arch Dermatol Res 2004 296: 89 93.
-
(2004)
Arch Dermatol Res
, vol.296
, pp. 89-93
-
-
Hasegawa, M.1
Sato, S.2
Takehara, K.3
-
99
-
-
0035089825
-
Blockade of endogenous transforming growth factor β signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: Association with increased expression of transforming growth factor β receptors
-
Ihn H, Yamane K, Kubo M, Tamaki K. Blockade of endogenous transforming growth factor β signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: association with increased expression of transforming growth factor β receptors. Arthritis Rheum 2001 44: 474 480.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 474-480
-
-
Ihn, H.1
Yamane, K.2
Kubo, M.3
Tamaki, K.4
-
100
-
-
0026666859
-
Direct demonstration of transcriptional activation of collagen gene expression in systemic sclerosis fibroblasts
-
Kikuchi K, Smith EA, LeRoy EC, Trojanowska M. Direct demonstration of transcriptional activation of collagen gene expression in systemic sclerosis fibroblasts. Biochem Biophys Res Commun 1992 187: 45 50.
-
(1992)
Biochem Biophys Res Commun
, vol.187
, pp. 45-50
-
-
Kikuchi, K.1
Smith, E.A.2
Leroy, E.C.3
Trojanowska, M.4
-
101
-
-
33746141265
-
Involvement of αvβ5 integrin in the establishment of autocrine TGF-β signaling in dermal fibroblasts derived from localized scleroderma
-
Asano Y, Ihn H, Jinnin M, Mimura Y, Tamaki K. Involvement of αvβ5 integrin in the establishment of autocrine TGF-β signaling in dermal fibroblasts derived from localized scleroderma. J Invest Dermatol 2006 126: 1761 1769.
-
(2006)
J Invest Dermatol
, vol.126
, pp. 1761-1769
-
-
Asano, Y.1
Ihn, H.2
Jinnin, M.3
Mimura, Y.4
Tamaki, K.5
-
102
-
-
25444501226
-
Involvement of αvβ5 integrin-mediated activation of latent transforming growth factor β1 in autocrine transforming growth factor β signaling in systemic sclerosis fibroblasts
-
Asano Y, Ihn H, Yamane K, Jinnin M, Mimura Y, Tamaki K. Involvement of αvβ5 integrin-mediated activation of latent transforming growth factor β1 in autocrine transforming growth factor β signaling in systemic sclerosis fibroblasts. Arthritis Rheum 2005 52: 2897 2905.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2897-2905
-
-
Asano, Y.1
Ihn, H.2
Yamane, K.3
Jinnin, M.4
Mimura, Y.5
Tamaki, K.6
-
103
-
-
0033036099
-
Role of transforming growth factor β type II receptor in hepatic fibrosis: Studies of human chronic hepatitis C and experimental fibrosis in rats
-
Roulot D, Sevcsik AM, Coste T, Strosberg AD, Marullo S. Role of transforming growth factor β type II receptor in hepatic fibrosis: studies of human chronic hepatitis C and experimental fibrosis in rats. Hepatology 1999 29: 1730 1738.
-
(1999)
Hepatology
, vol.29
, pp. 1730-1738
-
-
Roulot, D.1
Sevcsik, A.M.2
Coste, T.3
Strosberg, A.D.4
Marullo, S.5
-
104
-
-
0031886413
-
Increased expression of TGF-β receptors by scleroderma fibroblasts: Evidence for contribution of autocrine TGF-β signaling to scleroderma phenotype
-
Kawakami T, Ihn H, Xu W, Smith E, LeRoy C, Trojanowska M. Increased expression of TGF-β receptors by scleroderma fibroblasts: evidence for contribution of autocrine TGF-β signaling to scleroderma phenotype. J Invest Dermatol 1998 110: 47 51.
-
(1998)
J Invest Dermatol
, vol.110
, pp. 47-51
-
-
Kawakami, T.1
Ihn, H.2
Xu, W.3
Smith, E.4
Leroy, C.5
Trojanowska, M.6
-
105
-
-
2342547687
-
An increased transforming growth factor β receptor type I:type II ratio contributes to elevated collagen protein synthesis that is resistant to inhibition via a kinase-deficient transforming growth factor β receptor type II in scleroderma
-
Pannu J, Gore-Hyer E, Yamanaka M et al. An increased transforming growth factor β receptor type I:type II ratio contributes to elevated collagen protein synthesis that is resistant to inhibition via a kinase-deficient transforming growth factor β receptor type II in scleroderma. Arthritis Rheum 2004 50: 1566 1577.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1566-1577
-
-
Pannu, J.1
Gore-Hyer, E.2
Yamanaka, M.3
-
106
-
-
0025222517
-
Transforming growth factor-β family
-
Massague J. Transforming growth factor-β family. Ann Rev Cell Biol 1990 6: 597 641.
-
(1990)
Ann Rev Cell Biol
, vol.6
, pp. 597-641
-
-
Massague, J.1
-
107
-
-
0024323330
-
A strategy for determining the pathogenesis of systemic sclerosis. Is transforming growth factor β the answer
-
LeRoy EC, Smith EA, Kahaleh MB, Trojanowska M, Silver RM. A strategy for determining the pathogenesis of systemic sclerosis. Is transforming growth factor β the answer Arthritis Rheum 1989 32: 817 825.
-
(1989)
Arthritis Rheum
, vol.32
, pp. 817-825
-
-
Leroy, E.C.1
Smith, E.A.2
Kahaleh, M.B.3
Trojanowska, M.4
Silver, R.M.5
-
108
-
-
0028854277
-
Myofibroblasts from scleroderma skin synthesize elevated levels of collagen and tissue inhibitor of metalloproteinase (TIMP-1) with two forms of TIMP-1
-
Kirk TZ, Mark ME, Chua CC, Chua BH, Mayes MD. Myofibroblasts from scleroderma skin synthesize elevated levels of collagen and tissue inhibitor of metalloproteinase (TIMP-1) with two forms of TIMP-1. J Biol Chem 1995 270: 3423 3428.
-
(1995)
J Biol Chem
, vol.270
, pp. 3423-3428
-
-
Kirk, T.Z.1
Mark, M.E.2
Chua, C.C.3
Chua, B.H.4
Mayes, M.D.5
-
109
-
-
33645805628
-
Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type i collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts
-
Fineschi S, Reith W, Guerne PA, Dayer JM, Chizzolini C. Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts. FASEB J 2006 20: 562 564.
-
(2006)
FASEB J
, vol.20
, pp. 562-564
-
-
Fineschi, S.1
Reith, W.2
Guerne, P.A.3
Dayer, J.M.4
Chizzolini, C.5
-
110
-
-
42549131051
-
Connective tissue growth factor: Structure-function relationships of a mosaic, multifunctional protein
-
De WinterP, Leoni P, Abraham D. Connective tissue growth factor: structure-function relationships of a mosaic, multifunctional protein. Growth Factors 2008 26: 80 91.
-
(2008)
Growth Factors
, vol.26
, pp. 80-91
-
-
De Winter, P.1
Leoni, P.2
Abraham, D.3
-
111
-
-
0027229995
-
Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair
-
Igarashi A, Okochi H, Bradham DM, Grotendorst GR. Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair. Mol Biol Cell 1993 4: 637 645.
-
(1993)
Mol Biol Cell
, vol.4
, pp. 637-645
-
-
Igarashi, A.1
Okochi, H.2
Bradham, D.M.3
Grotendorst, G.R.4
-
112
-
-
0029816069
-
Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor
-
Frazier K, Williams S, Kothapalli D, Klapper H, Grotendorst GR. Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor. J Invest Dermatol 1996 107: 404 411.
-
(1996)
J Invest Dermatol
, vol.107
, pp. 404-411
-
-
Frazier, K.1
Williams, S.2
Kothapalli, D.3
Klapper, H.4
Grotendorst, G.R.5
-
113
-
-
16344369209
-
Connective tissue growth factor causes persistent proα2(I) collagen gene expression induced by transforming growth factor-beta in a mouse fibrosis model
-
Chujo S, Shirasaki F, Kawara S et al. Connective tissue growth factor causes persistent proα2(I) collagen gene expression induced by transforming growth factor-beta in a mouse fibrosis model. J Cell Physiol 2005 203: 447 456.
-
(2005)
J Cell Physiol
, vol.203
, pp. 447-456
-
-
Chujo, S.1
Shirasaki, F.2
Kawara, S.3
-
114
-
-
48749112311
-
Neutralizing monoclonal antibody to human connective tissue growth factor ameliorates transforming growth factor-β-induced mouse fibrosis
-
Ikawa Y, Ng PS, Endo K et al. Neutralizing monoclonal antibody to human connective tissue growth factor ameliorates transforming growth factor-β-induced mouse fibrosis. J Cell Physiol 2008 216: 680 687.
-
(2008)
J Cell Physiol
, vol.216
, pp. 680-687
-
-
Ikawa, Y.1
Ng, P.S.2
Endo, K.3
-
115
-
-
0037384658
-
Hypothesis: Pathogenesis of systemic sclerosis
-
Takehara K. Hypothesis: pathogenesis of systemic sclerosis. J Rheumatol 2003 30: 755 759.
-
(2003)
J Rheumatol
, vol.30
, pp. 755-759
-
-
Takehara, K.1
-
116
-
-
65549108648
-
Role of connective tissue growth factor and its interaction with basic fibroblast growth factor and macrophage chemoattractant protein-1 in skin fibrosis
-
Chujo S, Shirasaki F, Kondo-Miyazaki M, Ikawa Y, Takehara K. Role of connective tissue growth factor and its interaction with basic fibroblast growth factor and macrophage chemoattractant protein-1 in skin fibrosis. J Cell Physiol 2009 220: 189 195.
-
(2009)
J Cell Physiol
, vol.220
, pp. 189-195
-
-
Chujo, S.1
Shirasaki, F.2
Kondo-Miyazaki, M.3
Ikawa, Y.4
Takehara, K.5
-
117
-
-
0033978653
-
Serum levels of connective tissue growth factor are elevated in patients with systemic sclerosis: Association with extent of skin sclerosis and severity of pulmonary fibrosis
-
Sato S, Nagaoka T, Hasegawa M et al. Serum levels of connective tissue growth factor are elevated in patients with systemic sclerosis: association with extent of skin sclerosis and severity of pulmonary fibrosis. J Rheumatol 2000 27: 149 154.
-
(2000)
J Rheumatol
, vol.27
, pp. 149-154
-
-
Sato, S.1
Nagaoka, T.2
Hasegawa, M.3
-
118
-
-
0029154782
-
Significant correlation between connective tissue growth factor gene expression and skin sclerosis in tissue sections from patients with systemic sclerosis
-
Aug
-
Igarashi A, Nashiro K, Kikuchi K et al. Significant correlation between connective tissue growth factor gene expression and skin sclerosis in tissue sections from patients with systemic sclerosis. J Invest Dermatol 1995 (Aug 105 (2 280 284.
-
(1995)
J Invest Dermatol
, vol.105
, Issue.2
, pp. 280-284
-
-
Igarashi, A.1
Nashiro, K.2
Kikuchi, K.3
-
119
-
-
0035161153
-
Transforming growth factor-β and connective tissue growth factor: Key cytokines in scleroderma pathogenesis
-
Denton CP, Abraham DJ. Transforming growth factor-β and connective tissue growth factor: key cytokines in scleroderma pathogenesis. Curr Opin Rheumatol 2001 13: 505 511.
-
(2001)
Curr Opin Rheumatol
, vol.13
, pp. 505-511
-
-
Denton, C.P.1
Abraham, D.J.2
-
120
-
-
0035815683
-
CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling
-
Holmes A, Abraham DJ, Sa S, Shiwen X, Black CM, Leask A. CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling. J Biol Chem 2001 276: 10594 10601.
-
(2001)
J Biol Chem
, vol.276
, pp. 10594-10601
-
-
Holmes, A.1
Abraham, D.J.2
Sa, S.3
Shiwen, X.4
Black, C.M.5
Leask, A.6
-
121
-
-
34548843398
-
A polymorphism in the CTGF promoter region associated with systemic sclerosis
-
Fonseca C, Lindahl GE, Ponticos M et al. A polymorphism in the CTGF promoter region associated with systemic sclerosis. N Engl J Med 2007 357: 1210 1220.
-
(2007)
N Engl J Med
, vol.357
, pp. 1210-1220
-
-
Fonseca, C.1
Lindahl, G.E.2
Ponticos, M.3
-
122
-
-
0033524863
-
IL-1 rescues scleroderma myofibroblasts from serum-starvation-induced cell death
-
Kirk TZ, Mayes MD. IL-1 rescues scleroderma myofibroblasts from serum-starvation-induced cell death. Biochem Biophys Res Commun 1999 255: 129 132.
-
(1999)
Biochem Biophys Res Commun
, vol.255
, pp. 129-132
-
-
Kirk, T.Z.1
Mayes, M.D.2
-
123
-
-
5044232255
-
Autocrine activation by interleukin 1α induces the fibrogenic phenotype of systemic sclerosis fibroblasts
-
Kawaguchi Y, McCarthy SA, Watkins SC, Wright TM. Autocrine activation by interleukin 1α induces the fibrogenic phenotype of systemic sclerosis fibroblasts. J Rheumatol 2004 31: 1946 1954.
-
(2004)
J Rheumatol
, vol.31
, pp. 1946-1954
-
-
Kawaguchi, Y.1
McCarthy, S.A.2
Watkins, S.C.3
Wright, T.M.4
-
124
-
-
0033121274
-
Endogenous IL-1α from systemic sclerosis fibroblasts induces IL-6 and PDGF-A
-
Kawaguchi Y, Hara M, Wright TM. Endogenous IL-1α from systemic sclerosis fibroblasts induces IL-6 and PDGF-A. J Clin Invest 1999 103: 1253 1260.
-
(1999)
J Clin Invest
, vol.103
, pp. 1253-1260
-
-
Kawaguchi, Y.1
Hara, M.2
Wright, T.M.3
-
125
-
-
0042190656
-
A nuclear target for interleukin-1α: Interaction with the growth suppressor necdin modulates proliferation and collagen expression
-
Hu B, Wang S, Zhang Y, Feghali CA, Dingman JR, Wright TM. A nuclear target for interleukin-1α: interaction with the growth suppressor necdin modulates proliferation and collagen expression. Proc Natl Acad Sci USA 2003 100: 10008 10013.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10008-10013
-
-
Hu, B.1
Wang, S.2
Zhang, Y.3
Feghali, C.A.4
Dingman, J.R.5
Wright, T.M.6
-
126
-
-
0025005820
-
Interleukin-1β prevents the stimulatory effect of transforming growth factor-β on collagen gene expression in human skin fibroblasts
-
Heino J, Heinonen T. Interleukin-1β prevents the stimulatory effect of transforming growth factor-β on collagen gene expression in human skin fibroblasts. Biochem J 1990 71: 827 830.
-
(1990)
Biochem J
, vol.71
, pp. 827-830
-
-
Heino, J.1
Heinonen, T.2
-
127
-
-
36849042152
-
Interleukin-1β and macrophage migration inhibitory factor (MIF) in dermal fibroblasts mediate UVA-induced matrix metalloproteinase-1 expression
-
Honda A, Abe R, Makino T et al. Interleukin-1β and macrophage migration inhibitory factor (MIF) in dermal fibroblasts mediate UVA-induced matrix metalloproteinase-1 expression. J Dermatol Sci 2008 49: 63 72.
-
(2008)
J Dermatol Sci
, vol.49
, pp. 63-72
-
-
Honda, A.1
Abe, R.2
Makino, T.3
-
128
-
-
0021137232
-
Induction of fibroblast proliferation by interleukin-1 derived from human monocytic leukemia cells
-
Postlethwaite AE, Lachman LB, Kang AH. Induction of fibroblast proliferation by interleukin-1 derived from human monocytic leukemia cells. Arthritis Rheum 1984 27: 995 1001.
-
(1984)
Arthritis Rheum
, vol.27
, pp. 995-1001
-
-
Postlethwaite, A.E.1
Lachman, L.B.2
Kang, A.H.3
-
129
-
-
0026731946
-
The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes
-
Morgan JG, Dolganov GM, Robbins SE, Hinton LM, Lovett M. The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes. Nucleic Acids Res 1992 20: 5173 5179.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 5173-5179
-
-
Morgan, J.G.1
Dolganov, G.M.2
Robbins, S.E.3
Hinton, L.M.4
Lovett, M.5
-
130
-
-
0027274890
-
Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction
-
Zurawski SM, Vega F Jr., Huyghe B, Zurawski G. Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction. EMBO J 1993 12: 2663 2670.
-
(1993)
EMBO J
, vol.12
, pp. 2663-2670
-
-
Zurawski, S.M.1
Vega Jr., F.2
Huyghe, B.3
Zurawski, G.4
-
131
-
-
0031056613
-
Elevated serum levels of interleukin 4 (IL-4), IL-10, and IL-13 in patients with systemic sclerosis
-
Hasegawa M, Fujimoto M, Kikuchi K, Takehara K. Elevated serum levels of interleukin 4 (IL-4), IL-10, and IL-13 in patients with systemic sclerosis. J Rheumatol 1997 24: 328 332.
-
(1997)
J Rheumatol
, vol.24
, pp. 328-332
-
-
Hasegawa, M.1
Fujimoto, M.2
Kikuchi, K.3
Takehara, K.4
-
132
-
-
0026601232
-
Interleukin-1, interleukin-2, interleukin-4, interleukin-6, tumor necrosis factor α, and interferon-γ levels in sera from patients with scleroderma
-
Needleman BW, Fredrick M, Wigley M, Stair RW. Interleukin-1, interleukin-2, interleukin-4, interleukin-6, tumor necrosis factor α, and interferon-γ levels in sera from patients with scleroderma. Arthritis Rheum 1992 35: 67 72.
-
(1992)
Arthritis Rheum
, vol.35
, pp. 67-72
-
-
Needleman, B.W.1
Fredrick, M.2
Wigley, M.3
Stair, R.W.4
-
133
-
-
0029941568
-
Expression of interleukin-4 in scleroderma skin specimens and scleroderma fibroblast cultures. Potential role in fibrosis
-
Jul
-
Salmon-Ehr V, Serpier H, Nawrocki B et al. Expression of interleukin-4 in scleroderma skin specimens and scleroderma fibroblast cultures. Potential role in fibrosis. Arch Dermatol 1996 (Jul 132 (7 802 806.
-
(1996)
Arch Dermatol
, vol.132
, Issue.7
, pp. 802-806
-
-
Salmon-Ehr, V.1
Serpier, H.2
Nawrocki, B.3
-
134
-
-
4744362174
-
Interleukin-13 stimulates the transcription of the human α2(I) collagen gene in human dermal fibroblasts
-
Jinnin M, Ihn H, Yamane K, Tamaki K. Interleukin-13 stimulates the transcription of the human α2(I) collagen gene in human dermal fibroblasts. J Biol Chem 2004 279: 41783 41791.
-
(2004)
J Biol Chem
, vol.279
, pp. 41783-41791
-
-
Jinnin, M.1
Ihn, H.2
Yamane, K.3
Tamaki, K.4
-
135
-
-
0034104598
-
Interleukin-13 modulates collagen homeostasis in human skin and keloid fibroblasts
-
Oriente A, Fedarko NS, Pacocha SE, Huang SK, Lichtenstein LM, Essayan DM. Interleukin-13 modulates collagen homeostasis in human skin and keloid fibroblasts. J Pharmacol Exp Ther 2000 292: 988 994.
-
(2000)
J Pharmacol Exp Ther
, vol.292
, pp. 988-994
-
-
Oriente, A.1
Fedarko, N.S.2
Pacocha, S.E.3
Huang, S.K.4
Lichtenstein, L.M.5
Essayan, D.M.6
-
136
-
-
1642333177
-
Protection from fluorescein isothiocyanate-induced fibrosis in IL-13-deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts
-
Kolodsick JE, Toews GB, Jakubzick C et al. Protection from fluorescein isothiocyanate-induced fibrosis in IL-13-deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts. J Immunol 2004 172: 4068 4076.
-
(2004)
J Immunol
, vol.172
, pp. 4068-4076
-
-
Kolodsick, J.E.1
Toews, G.B.2
Jakubzick, C.3
-
137
-
-
0037083458
-
IL-4 up-regulates the expression of tissue inhibitor of metalloproteinase-2 in dermal fibroblasts via the p38 mitogen-activated protein kinase dependent pathway
-
Ihn H, Yamane K, Asano Y, Kubo M, Tamaki K. IL-4 up-regulates the expression of tissue inhibitor of metalloproteinase-2 in dermal fibroblasts via the p38 mitogen-activated protein kinase dependent pathway. J Immunol 2002 168: 1895 1902.
-
(2002)
J Immunol
, vol.168
, pp. 1895-1902
-
-
Ihn, H.1
Yamane, K.2
Asano, Y.3
Kubo, M.4
Tamaki, K.5
-
138
-
-
0029025990
-
Plasma endothelin-1 levels, pulmonary hypertension, and lung fibrosis in patients with systemic sclerosis
-
Morelli S, Ferri C, Polettini E et al. Plasma endothelin-1 levels, pulmonary hypertension, and lung fibrosis in patients with systemic sclerosis. Am J Med 1995 99: 255 260.
-
(1995)
Am J Med
, vol.99
, pp. 255-260
-
-
Morelli, S.1
Ferri, C.2
Polettini, E.3
-
139
-
-
0035095109
-
Fibroblast matrix gene expression and connective tissue remodeling: Role of endothelin-1
-
Shi-Wen X, Denton CP, Dashwood MR et al. Fibroblast matrix gene expression and connective tissue remodeling: role of endothelin-1. J Invest Dermatol 2001 116: 417 425.
-
(2001)
J Invest Dermatol
, vol.116
, pp. 417-425
-
-
Shi-Wen, X.1
Denton, C.P.2
Dashwood, M.R.3
-
140
-
-
2542485410
-
Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts
-
Jun
-
Shi-Wen X, Chen Y, Denton CP et al. Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts. Mol Biol Cell 2004 (Jun 15 (16 2707 2719.
-
(2004)
Mol Biol Cell
, vol.15
, Issue.16
, pp. 2707-2719
-
-
Shi-Wen, X.1
Chen, Y.2
Denton, C.P.3
-
141
-
-
0346458565
-
Angiotensin II in the lesional skin of systemic sclerosis patients contributes to tissue fibrosis via angiotensin II type 1 receptors
-
Jan
-
Kawaguchi Y, Takagi K, Hara M et al. Angiotensin II in the lesional skin of systemic sclerosis patients contributes to tissue fibrosis via angiotensin II type 1 receptors. Arthritis Rheum 2004 (Jan 50 (1 216 226.
-
(2004)
Arthritis Rheum
, vol.50
, Issue.1
, pp. 216-226
-
-
Kawaguchi, Y.1
Takagi, K.2
Hara, M.3
|