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Volumn 220, Issue , 2015, Pages 223-250

BDNF and synaptic plasticity, cognitive function, and dysfunction

Author keywords

Brain derived neurotrophic factor; MRNA trafficking; Synaptic plasticity

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C GAMMA1; PLASMIN; PROTEIN KINASE B; TISSUE PLASMINOGEN ACTIVATOR; 4 AMINOBUTYRIC ACID;

EID: 84900530338     PISSN: 01712004     EISSN: 18650325     Source Type: Book Series    
DOI: 10.1007/978-3-642-45106-5_9     Document Type: Article
Times cited : (742)

References (138)
  • 2
    • 0030861491 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor enhances long-term potentiation in rat visual cortex
    • Akaneya Y, Tsumoto T, Kinoshita S, Hatanaka H (1997) Brain-derived neurotrophic factor enhances long-term potentiation in rat visual cortex. J Neurosci 17:6707–6716
    • (1997) J Neurosci , vol.17 , pp. 6707-6716
    • Akaneya, Y.1    Tsumoto, T.2    Kinoshita, S.3    Hatanaka, H.4
  • 4
    • 0036973397 scopus 로고    scopus 로고
    • Signaling mechanisms mediating BDNF modulation of memory formation in vivo in the hippocampus
    • Alonso M, Vianna MR, Izquierdo I, Medina JH (2002b) Signaling mechanisms mediating BDNF modulation of memory formation in vivo in the hippocampus. Cell Mol Neurobiol 22:663–674
    • (2002) Cell Mol Neurobiol , vol.22 , pp. 663-674
    • Alonso, M.1    Vianna, M.R.2    Izquierdo, I.3    Medina, J.H.4
  • 6
    • 2442452710 scopus 로고    scopus 로고
    • Direct current stimulation over V5 enhances visuomotor coordination by improving motion perception in humans
    • Antal A, Nitsche MA, Kruse W, Kincses TZ, Hoffmann KP, Paulus W (2004) Direct current stimulation over V5 enhances visuomotor coordination by improving motion perception in humans. J Cogn Neurosci 16:521–527
    • (2004) J Cogn Neurosci , vol.16 , pp. 521-527
    • Antal, A.1    Nitsche, M.A.2    Kruse, W.3    Kincses, T.Z.4    Hoffmann, K.P.5    Paulus, W.6
  • 8
    • 77954117659 scopus 로고    scopus 로고
    • Activation of adenosine A2A receptors induces TrkB translocation and increases BDNF- mediated phospho-TrkB localization in lipid rafts: Implications for neuromodulation
    • Assaife-Lopes N, Sousa VC, Pereira DB, Ribeiro JA, Chao MV, Sebastiao AM (2010) Activation of adenosine A2A receptors induces TrkB translocation and increases BDNF- mediated phospho-TrkB localization in lipid rafts: implications for neuromodulation. J Neurosci 30:8468–8480
    • (2010) J Neurosci , vol.30 , pp. 8468-8480
    • Assaife-Lopes, N.1    Sousa, V.C.2    Pereira, D.B.3    Ribeiro, J.A.4    Chao, M.V.5    Sebastiao, A.M.6
  • 10
    • 25644460530 scopus 로고    scopus 로고
    • Gene expression profiling of facilitated L-LTP in VP16-CREB mice reveals that BDNF is critical for the maintenance of LTP and its synaptic capture
    • Barco A, Patterson S, Alarcon JM, Gromova P, Mata-Roig M, Morozov A, Kandel ER (2005) Gene expression profiling of facilitated L-LTP in VP16-CREB mice reveals that BDNF is critical for the maintenance of LTP and its synaptic capture. Neuron 48:123–137
    • (2005) Neuron , vol.48 , pp. 123-137
    • Barco, A.1    Patterson, S.2    Alarcon, J.M.3    Gromova, P.4    Mata-Roig, M.5    Morozov, A.6    Kandel, E.R.7
  • 11
    • 54749091291 scopus 로고    scopus 로고
    • Proteolysis of proBDNF is a key regulator in the formation of memory
    • Barnes P, Thomas KL (2008) Proteolysis of proBDNF is a key regulator in the formation of memory. PLoS One 3:e3248
    • (2008) Plos One , vol.3
    • Barnes, P.1    Thomas, K.L.2
  • 13
    • 33846101430 scopus 로고    scopus 로고
    • Persistence of long-term memory storage requires a late protein synthesis- and BDNF-dependent phase in the hippocampus
    • Bekinschtein P, Cammarota M, Igaz LM, Bevilaqua LR, Izquierdo I, Medina JH (2007) Persistence of long-term memory storage requires a late protein synthesis- and BDNF-dependent phase in the hippocampus. Neuron 53:261–277
    • (2007) Neuron , vol.53 , pp. 261-277
    • Bekinschtein, P.1    Cammarota, M.2    Igaz, L.M.3    Bevilaqua, L.R.4    Izquierdo, I.5    Medina, J.H.6
  • 14
    • 34247224239 scopus 로고    scopus 로고
    • Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear
    • Bredy TW, Wu H, Crego C, Zellhoefer J, Sun YE, Barad M (2007) Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear. Learn Mem 14:268–276
    • (2007) Learn Mem , vol.14 , pp. 268-276
    • Bredy, T.W.1    Wu, H.2    Crego, C.3    Zellhoefer, J.4    Sun, Y.E.5    Barad, M.6
  • 15
    • 0036456585 scopus 로고    scopus 로고
    • Increased BDNF and trk-B mRNA expression in cortical and limbic regions following formation of a social recognition memory
    • Broad KD, Mimmack ML, Keverne EB, Kendrick KM (2002) Increased BDNF and trk-B mRNA expression in cortical and limbic regions following formation of a social recognition memory. Eur J Neurosci 16:2166–2174
    • (2002) Eur J Neurosci , vol.16 , pp. 2166-2174
    • Broad, K.D.1    Mimmack, M.L.2    Keverne, E.B.3    Kendrick, K.M.4
  • 17
    • 0033568871 scopus 로고    scopus 로고
    • Relative contribution of endogenous neurotrophins in hippocampal long-term potentiation
    • Chen G, Kolbeck R, Barde YA, Bonhoeffer T, Kossel A (1999) Relative contribution of endogenous neurotrophins in hippocampal long-term potentiation. J Neurosci 19:7983–7990
    • (1999) J Neurosci , vol.19 , pp. 7983-7990
    • Chen, G.1    Kolbeck, R.2    Barde, Y.A.3    Bonhoeffer, T.4    Kossel, A.5
  • 18
    • 2342550552 scopus 로고    scopus 로고
    • Variant brainderived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activitydependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons
    • Chen ZY, Patel PD, Sant G, Meng CX, Teng KK, Hempstead BL, Lee FS (2004) Variant brainderived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activitydependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons. J Neurosci 24:4401–4411
    • (2004) J Neurosci , vol.24 , pp. 4401-4411
    • Chen, Z.Y.1    Patel, P.D.2    Sant, G.3    Meng, C.X.4    Teng, K.K.5    Hempstead, B.L.6    Lee, F.S.7
  • 21
    • 33745582492 scopus 로고    scopus 로고
    • Amygdala BDNF signaling is required for consolidation but not encoding of extinction
    • Chhatwal JP, Stanek-Rattiner L, Davis M, Ressler KJ (2006) Amygdala BDNF signaling is required for consolidation but not encoding of extinction. Nat Neurosci 9:870–872
    • (2006) Nat Neurosci , vol.9 , pp. 870-872
    • Chhatwal, J.P.1    Stanek-Rattiner, L.2    Davis, M.3    Ressler, K.J.4
  • 24
    • 60849118637 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF) overexpression in the forebrain results in learning and memory impairments
    • Cunha C, Angelucci A, D’Antoni A, Dobrossy MD, Dunnett SB, Berardi N, Brambilla R (2009) Brain-derived neurotrophic factor (BDNF) overexpression in the forebrain results in learning and memory impairments. Neurobiol Dis 33:358–368
    • (2009) Neurobiol Dis , vol.33 , pp. 358-368
    • Cunha, C.1    Angelucci, A.2    D’Antoni, A.3    Dobrossy, M.D.4    Dunnett, S.B.5    Berardi, N.6    Brambilla, R.7
  • 26
    • 0034683575 scopus 로고    scopus 로고
    • Activity- and Ca(2+)-dependent modulation of surface expression of brain-derived neurotrophic factor receptors in hippocampal neurons
    • Du J, Feng L, Yang F, Lu B (2000) Activity- and Ca(2+)-dependent modulation of surface expression of brain-derived neurotrophic factor receptors in hippocampal neurons. J Cell Biol 150:1423–1434
    • (2000) J Cell Biol , vol.150 , pp. 1423-1434
    • Du, J.1    Feng, L.2    Yang, F.3    Lu, B.4
  • 28
    • 0029970008 scopus 로고    scopus 로고
    • Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus
    • Figurov A, Pozzo-Miller LD, Olafsson P, Wang T, Lu B (1996) Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature 381:706–709
    • (1996) Nature , vol.381 , pp. 706-709
    • Figurov, A.1    Pozzo-Miller, L.D.2    Olafsson, P.3    Wang, T.4    Lu, B.5
  • 29
    • 0029946148 scopus 로고    scopus 로고
    • BDNF down-regulates neurotrophin responsiveness, TrkB protein and TrkB mRNA levels in cultured rat hippocampal neurons
    • Frank L, Ventimiglia R, Anderson K, Lindsay RM, Rudge JS (1996) BDNF down-regulates neurotrophin responsiveness, TrkB protein and TrkB mRNA levels in cultured rat hippocampal neurons. Eur J Neurosci 8:1220–1230
    • (1996) Eur J Neurosci , vol.8 , pp. 1220-1230
    • Frank, L.1    Ventimiglia, R.2    Erson, K.3    Lindsay, R.M.4    Rudge, J.S.5
  • 32
    • 0032429305 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF) modulates inhibitory, but not excitatory, transmission in the CA1 region of the hippocampus
    • Frerking M, Malenka RC, Nicoll RA (1998) Brain-derived neurotrophic factor (BDNF) modulates inhibitory, but not excitatory, transmission in the CA1 region of the hippocampus. J Neurophysiol 80:3383–3386
    • (1998) J Neurophysiol , vol.80 , pp. 3383-3386
    • Frerking, M.1    Malenka, R.C.2    Nicoll, R.A.3
  • 33
    • 0031024891 scopus 로고    scopus 로고
    • Synaptic tagging and long-term potentiation
    • Frey U, Morris RG (1997) Synaptic tagging and long-term potentiation. Nature 385:533–536
    • (1997) Nature , vol.385 , pp. 533-536
    • Frey, U.1    Morris, R.G.2
  • 34
    • 0029924091 scopus 로고    scopus 로고
    • A different form of long-lasting potentiation revealed in tissue plasminogen activator mutant mice
    • Frey U, Muller M, Kuhl D (1996) A different form of long-lasting potentiation revealed in tissue plasminogen activator mutant mice. J Neurosci 16:2057–2063
    • (1996) J Neurosci , vol.16 , pp. 2057-2063
    • Frey, U.1    Muller, M.2    Kuhl, D.3
  • 35
    • 25144464991 scopus 로고    scopus 로고
    • A mechanism for cognitive dynamics: Neuronal communication through neuronal coherence
    • Fries P (2005) A mechanism for cognitive dynamics: neuronal communication through neuronal coherence. Trends Cogn Sci 9:474–480
    • (2005) Trends Cogn Sci , vol.9 , pp. 474-480
    • Fries, P.1
  • 36
    • 77952416389 scopus 로고    scopus 로고
    • Direct current stimulation promotes BDNF-dependent synaptic plasticity: Potential implications for motor learning
    • Fritsch B, Reis J, Martinowich K, Schambra HM, Ji Y, Cohen LG, Lu B (2010) Direct current stimulation promotes BDNF-dependent synaptic plasticity: potential implications for motor learning. Neuron 66:198–204
    • (2010) Neuron , vol.66 , pp. 198-204
    • Fritsch, B.1    Reis, J.2    Martinowich, K.3    Schambra, H.M.4    Ji, Y.5    Cohen, L.G.6    Lu, B.7
  • 37
    • 77951520355 scopus 로고    scopus 로고
    • Betaadrenergic receptors link NO/sGC/PKG signaling to BDNF expression during the consolidation of object recognition long-term memory
    • Furini CR, Rossato JI, Bitencourt LL, Medina JH, Izquierdo I, Cammarota M (2009) Betaadrenergic receptors link NO/sGC/PKG signaling to BDNF expression during the consolidation of object recognition long-term memory. Hippocampus 20:672–683
    • (2009) Hippocampus , vol.20 , pp. 672-683
    • Furini, C.R.1    Rossato, J.I.2    Bitencourt, L.L.3    Medina, J.H.4    Izquierdo, I.5    Cammarota, M.6
  • 38
    • 33644914451 scopus 로고    scopus 로고
    • Transcranial DC stimulation (TDCS): A tool for double-blind sham-controlled clinical studies in brain stimulation
    • Gandiga PC, Hummel FC, Cohen LG (2006) Transcranial DC stimulation (tDCS): a tool for double-blind sham-controlled clinical studies in brain stimulation. Clin Neurophysiol 117:845–850
    • (2006) Clin Neurophysiol , vol.117 , pp. 845-850
    • Gandiga, P.C.1    Hummel, F.C.2    Cohen, L.G.3
  • 39
    • 0141867812 scopus 로고    scopus 로고
    • Learning deficits in forebrain-restricted brain-derived neurotrophic factor mutant mice
    • Gorski JA, Balogh SA, Wehner JM, Jones KR (2003) Learning deficits in forebrain-restricted brain-derived neurotrophic factor mutant mice. Neuroscience 121:341–354
    • (2003) Neuroscience , vol.121 , pp. 341-354
    • Gorski, J.A.1    Balogh, S.A.2    Wehner, J.M.3    Jones, K.R.4
  • 40
    • 78650965110 scopus 로고    scopus 로고
    • The dendritic branch is the preferred integrative unit for protein synthesis-dependent LTP
    • Govindarajan A, Israely I, Huang SY, Tonegawa S (2011) The dendritic branch is the preferred integrative unit for protein synthesis-dependent LTP. Neuron 69:132–146
    • (2011) Neuron , vol.69 , pp. 132-146
    • Govindarajan, A.1    Israely, I.2    Huang, S.Y.3    Tonegawa, S.4
  • 42
    • 0034114247 scopus 로고    scopus 로고
    • Rapid and selective induction of BDNF expression in the hippocampus during contextual learning
    • Hall J, Thomas KL, Everitt BJ (2000) Rapid and selective induction of BDNF expression in the hippocampus during contextual learning. Nat Neurosci 3:533–535
    • (2000) Nat Neurosci , vol.3 , pp. 533-535
    • Hall, J.1    Thomas, K.L.2    Everitt, B.J.3
  • 43
    • 0036498257 scopus 로고    scopus 로고
    • Location, location, location: A spatial view of neurotrophin signal transduction
    • Heerssen HM, Segal RA (2002) Location, location, location: a spatial view of neurotrophin signal transduction. Trends Neurosci 25:160–165
    • (2002) Trends Neurosci , vol.25 , pp. 160-165
    • Heerssen, H.M.1    Segal, R.A.2
  • 44
    • 34247856252 scopus 로고    scopus 로고
    • Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories
    • Heldt SA, Stanek L, Chhatwal JP, Ressler KJ (2007) Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories. Mol Psychiatry 12:656–670
    • (2007) Mol Psychiatry , vol.12 , pp. 656-670
    • Heldt, S.A.1    Stanek, L.2    Chhatwal, J.P.3    Ressler, K.J.4
  • 45
    • 70349857870 scopus 로고    scopus 로고
    • Mature BDNF, but not proBDNF, reduces excitability of fast-spiking interneurons in mouse dentate gyrus
    • Holm MM, Nieto-Gonzalez JL, Vardya I, Vaegter CB, Nykjaer A, Jensen K (2009) Mature BDNF, but not proBDNF, reduces excitability of fast-spiking interneurons in mouse dentate gyrus. J Neurosci 29:12412–12418
    • (2009) J Neurosci , vol.29 , pp. 12412-12418
    • Holm, M.M.1    Nieto-Gonzalez, J.L.2    Vardya, I.3    Vaegter, C.B.4    Nykjaer, A.5    Jensen, K.6
  • 46
    • 52049117013 scopus 로고    scopus 로고
    • A biological function for the neuronal activitydependent component of Bdnf transcription in the development of cortical inhibition
    • Hong EJ, McCord AE, Greenberg ME (2008) A biological function for the neuronal activitydependent component of Bdnf transcription in the development of cortical inhibition. Neuron 60:610–624
    • (2008) Neuron , vol.60 , pp. 610-624
    • Hong, E.J.1    McCord, A.E.2    Greenberg, M.E.3
  • 47
    • 0041488911 scopus 로고    scopus 로고
    • Trk receptors: Roles in neuronal signal transduction
    • Huang EJ, Reichardt LF (2003) Trk receptors: roles in neuronal signal transduction. Annu Rev Biochem 72:609–642
    • (2003) Annu Rev Biochem , vol.72 , pp. 609-642
    • Huang, E.J.1    Reichardt, L.F.2
  • 50
    • 0031748884 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor alters the synaptic modification threshold in visual cortex
    • Huber KM, Sawtell NB, Bear MF (1998) Brain-derived neurotrophic factor alters the synaptic modification threshold in visual cortex. Neuropharmacology 37:571–579
    • (1998) Neuropharmacology , vol.37 , pp. 571-579
    • Huber, K.M.1    Sawtell, N.B.2    Bear, M.F.3
  • 51
    • 15744365886 scopus 로고    scopus 로고
    • Activation of the Trk signaling pathway by extracellular zinc. Role of metalloproteinases
    • Hwang JJ, Park MH, Choi SY, Koh JY (2005) Activation of the Trk signaling pathway by extracellular zinc. Role of metalloproteinases. J Biol Chem 280:11995–12001
    • (2005) J Biol Chem , vol.280 , pp. 11995-12001
    • Hwang, J.J.1    Park, M.H.2    Choi, S.Y.3    Koh, J.Y.4
  • 52
    • 14744277607 scopus 로고    scopus 로고
    • Safety and cognitive effect of frontal DC brain polarization in healthy individuals
    • Iyer MB, Mattu U, Grafman J, Lomarev M, Sato S, Wassermann EM (2005) Safety and cognitive effect of frontal DC brain polarization in healthy individuals. Neurology 64:872–875
    • (2005) Neurology , vol.64 , pp. 872-875
    • Iyer, M.B.1    Mattu, U.2    Grafman, J.3    Lomarev, M.4    Sato, S.5    Wassermann, E.M.6
  • 53
    • 13244279632 scopus 로고    scopus 로고
    • Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons
    • Ji Y, Pang PT, Feng L, Lu B (2005) Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons. Nat Neurosci 8:164–172
    • (2005) Nat Neurosci , vol.8 , pp. 164-172
    • Ji, Y.1    Pang, P.T.2    Feng, L.3    Lu, B.4
  • 54
    • 77649190522 scopus 로고    scopus 로고
    • Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons
    • Ji Y, Lu Y, Yang F, Shen W, Tang TT, Feng L, Duan S, Lu B (2010) Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons. Nat Neurosci 13:302–309
    • (2010) Nat Neurosci , vol.13 , pp. 302-309
    • Ji, Y.1    Lu, Y.2    Yang, F.3    Shen, W.4    Tang, T.T.5    Feng, L.6    Duan, S.7    Lu, B.8
  • 55
    • 0035783691 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor induces long-lasting potentiation of synaptic transmission in visual cortex in vivo in young rats, but not in the adult
    • Jiang B, Akaneya Y, Ohshima M, Ichisaka S, Hata Y, Tsumoto T (2001) Brain-derived neurotrophic factor induces long-lasting potentiation of synaptic transmission in visual cortex in vivo in young rats, but not in the adult. Eur J Neurosci 14:1219–1228
    • (2001) Eur J Neurosci , vol.14 , pp. 1219-1228
    • Jiang, B.1    Akaneya, Y.2    Ohshima, M.3    Ichisaka, S.4    Hata, Y.5    Tsumoto, T.6
  • 56
    • 79961084076 scopus 로고    scopus 로고
    • A key mechanism underlying sensory experience-dependent maturation of neocortical GABAergic circuits in vivo
    • Jiao Y, Zhang Z, Zhang C, Wang X, Sakata K, Lu B, Sun QQ (2011) A key mechanism underlying sensory experience-dependent maturation of neocortical GABAergic circuits in vivo. Proc Natl Acad Sci U S A 108:12131–12136
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 12131-12136
    • Jiao, Y.1    Zhang, Z.2    Zhang, C.3    Wang, X.4    Sakata, K.5    Lu, B.6    Sun, Q.Q.7
  • 57
    • 84859366504 scopus 로고    scopus 로고
    • Dendritic BDNF synthesis is required for latephase spine maturation and recovery of cortical responses following sensory deprivation
    • Kaneko M, Xie Y, An JJ, Stryker MP, Xu B (2012) Dendritic BDNF synthesis is required for latephase spine maturation and recovery of cortical responses following sensory deprivation. J Neurosci 32:4790–4802
    • (2012) J Neurosci , vol.32 , pp. 4790-4802
    • Kaneko, M.1    Xie, Y.2    An, J.J.3    Stryker, M.P.4    Xu, B.5
  • 58
    • 0347298828 scopus 로고    scopus 로고
    • Association of partial epilepsy with brain-derived neurotrophic factor (BDNF) gene polymorphisms
    • Kanemoto K, Kawasaki J, Tarao Y, Kumaki T, Oshima T, Kaji R, Nishimura M (2003) Association of partial epilepsy with brain-derived neurotrophic factor (BDNF) gene polymorphisms. Epilepsy Res 53:255–258
    • (2003) Epilepsy Res , vol.53 , pp. 255-258
    • Kanemoto, K.1    Kawasaki, J.2    Tarao, Y.3    Kumaki, T.4    Oshima, T.5    Kaji, R.6    Nishimura, M.7
  • 59
    • 0028988240 scopus 로고
    • Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus
    • Kang H, Schuman EM (1995) Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus. Science 267:1658–1662
    • (1995) Science , vol.267 , pp. 1658-1662
    • Kang, H.1    Schuman, E.M.2
  • 60
    • 0030967828 scopus 로고    scopus 로고
    • Neurotrophins and time: Different roles for TrkB signaling in hippocampal long-term potentiation
    • Kang H, Welcher AA, Shelton D, Schuman EM (1997) Neurotrophins and time: different roles for TrkB signaling in hippocampal long-term potentiation. Neuron 19:653–664
    • (1997) Neuron , vol.19 , pp. 653-664
    • Kang, H.1    Welcher, A.A.2    Shelton, D.3    Schuman, E.M.4
  • 61
    • 72449160066 scopus 로고    scopus 로고
    • Cleavage of proBDNF to BDNF by a tolloid-like metalloproteinase is required for acquisition of in vitro eyeblink classical conditioning
    • Keifer J, Sabirzhanov BE, Zheng Z, Li W, Clark TG (2009) Cleavage of proBDNF to BDNF by a tolloid-like metalloproteinase is required for acquisition of in vitro eyeblink classical conditioning. J Neurosci 29:14956–14964
    • (2009) J Neurosci , vol.29 , pp. 14956-14964
    • Keifer, J.1    Sabirzhanov, B.E.2    Zheng, Z.3    Li, W.4    Clark, T.G.5
  • 62
    • 5344244073 scopus 로고    scopus 로고
    • Translational regulatory mechanisms in persistent forms of synaptic plasticity
    • Kelleher RJ 3rd, Govindarajan A, Tonegawa S (2004) Translational regulatory mechanisms in persistent forms of synaptic plasticity. Neuron 44:59–73
    • (2004) Neuron , vol.44 , pp. 59-73
    • Kelleher, R.J.1    Govindarajan, A.2    Tonegawa, S.3
  • 63
    • 0031656199 scopus 로고    scopus 로고
    • Learning upregulates brainderived neurotrophic factor messenger ribonucleic acid: A mechanism to facilitate encoding and circuit maintenance?
    • Kesslak JP, So V, Choi J, Cotman CW, Gomez-Pinilla F (1998) Learning upregulates brainderived neurotrophic factor messenger ribonucleic acid: a mechanism to facilitate encoding and circuit maintenance? Behav Neurosci 112:1012–1019
    • (1998) Behav Neurosci , vol.112 , pp. 1012-1019
    • Kesslak, J.P.1    So, V.2    Choi, J.3    Cotman, C.W.4    Gomez-Pinilla, F.5
  • 64
    • 39849102665 scopus 로고    scopus 로고
    • Altered protein synthesis is a trigger for long-term memory formation
    • Klann E, Sweatt JD (2008) Altered protein synthesis is a trigger for long-term memory formation. Neurobiol Learn Mem 89:247–259
    • (2008) Neurobiol Learn Mem , vol.89 , pp. 247-259
    • Klann, E.1    Sweatt, J.D.2
  • 65
    • 33745684614 scopus 로고    scopus 로고
    • BDNF val66met polymorphism is associated with modified experience-dependent plasticity in human motor cortex
    • Kleim JA, Chan S, Pringle E, Schallert K, Procaccio V, Jimenez R, Cramer SC (2006) BDNF val66met polymorphism is associated with modified experience-dependent plasticity in human motor cortex. Nat Neurosci 9:735–737
    • (2006) Nat Neurosci , vol.9 , pp. 735-737
    • Kleim, J.A.1    Chan, S.2    Pringle, E.3    Schallert, K.4    Procaccio, V.5    Jimenez, R.6    Cramer, S.C.7
  • 66
    • 7244221842 scopus 로고    scopus 로고
    • Altered expression of BDNF and its high-affinity receptor TrkB in response to complex motor learning and moderate exercise
    • Klintsova AY, Dickson E, Yoshida R, Greenough WT (2004) Altered expression of BDNF and its high-affinity receptor TrkB in response to complex motor learning and moderate exercise. Brain Res 1028:92–104
    • (2004) Brain Res , vol.1028 , pp. 92-104
    • Klintsova, A.Y.1    Dickson, E.2    Yoshida, R.3    Greenough, W.T.4
  • 67
    • 2342472745 scopus 로고    scopus 로고
    • Transgenic mice overexpressing the full-length neurotrophin receptor trkB exhibit increased activation of the trkB-PLCgamma pathway, reduced anxiety, and facilitated learning
    • Koponen E, Voikar V, Riekki R, Saarelainen T, Rauramaa T, Rauvala H, Taira T, Castren E (2004) Transgenic mice overexpressing the full-length neurotrophin receptor trkB exhibit increased activation of the trkB-PLCgamma pathway, reduced anxiety, and facilitated learning. Mol Cell Neurosci 26:166–181
    • (2004) Mol Cell Neurosci , vol.26 , pp. 166-181
    • Koponen, E.1    Voikar, V.2    Riekki, R.3    Saarelainen, T.4    Rauramaa, T.5    Rauvala, H.6    Taira, T.7    Castren, E.8
  • 68
    • 0029021177 scopus 로고
    • Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor
    • Korte M, Carroll P, Wolf E, Brem G, Thoenen H, Bonhoeffer T (1995) Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proc Natl Acad Sci U S A 92:8856–8860
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 8856-8860
    • Korte, M.1    Carroll, P.2    Wolf, E.3    Brem, G.4    Thoenen, H.5    Bonhoeffer, T.6
  • 70
    • 77950339309 scopus 로고    scopus 로고
    • Distinct signaling pathways of precursor BDNF and mature BDNF in cultured cerebellar granule neurons
    • Koshimizu H, Hazama S, Hara T, Ogura A, Kojima M (2010) Distinct signaling pathways of precursor BDNF and mature BDNF in cultured cerebellar granule neurons. Neurosci Lett 473:229–232
    • (2010) Neurosci Lett , vol.473 , pp. 229-232
    • Koshimizu, H.1    Hazama, S.2    Hara, T.3    Ogura, A.4    Kojima, M.5
  • 72
    • 0026747063 scopus 로고
    • Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system
    • Lee KF, Li E, Huber LJ, Landis SC, Sharpe AH, Chao MV, Jaenisch R (1992) Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell 69:737–749
    • (1992) Cell , vol.69 , pp. 737-749
    • Lee, K.F.1    Li, E.2    Huber, L.J.3    Landis, S.C.4    Sharpe, A.H.5    Chao, M.V.6    Jaenisch, R.7
  • 73
    • 0035976524 scopus 로고    scopus 로고
    • Regulation of cell survival by secreted proneurotrophins
    • Lee R, Kermani P, Teng KK, Hempstead BL (2001) Regulation of cell survival by secreted proneurotrophins. Science 294:1945–1948
    • (2001) Science , vol.294 , pp. 1945-1948
    • Lee, R.1    Kermani, P.2    Teng, K.K.3    Hempstead, B.L.4
  • 75
    • 4544370251 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor plays a critical role in contextual fear conditioning
    • Liu IY, Lyons WE, Mamounas LA, Thompson RF (2004) Brain-derived neurotrophic factor plays a critical role in contextual fear conditioning. J Neurosci 24:7958–7963
    • (2004) J Neurosci , vol.24 , pp. 7958-7963
    • Liu, I.Y.1    Lyons, W.E.2    Mamounas, L.A.3    Thompson, R.F.4
  • 77
    • 31144467231 scopus 로고    scopus 로고
    • Uhl GR (2006) Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaine
    • Liu QR, Lu L, Zhu XG, Gong JP, Shaham Y, Uhl GR (2006) Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaine. Brain Res 1067:1–12
    • Brain Res , pp. 1-12
    • Liu, Q.R.1    Lu, L.2    Zhu, X.G.3    Gong, J.P.4    Shaham, Y.5
  • 80
    • 0342546629 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor antisense oligonucleotide impairs memory retention and inhibits long-term potentiation in rats
    • Ma YL, Wang HL, Wu HC, Wei CL, Lee EH (1998) Brain-derived neurotrophic factor antisense oligonucleotide impairs memory retention and inhibits long-term potentiation in rats. Neuroscience 82:957–967
    • (1998) Neuroscience , vol.82 , pp. 957-967
    • Ma, Y.L.1    Wang, H.L.2    Wu, H.C.3    Wei, C.L.4    Lee, E.H.5
  • 82
    • 79951537621 scopus 로고    scopus 로고
    • Region- specific involvement of BDNF secretion and synthesis in conditioned taste aversion memory formation
    • Ma L, Wang DD, Zhang TY, Yu H, Wang Y, Huang SH, Lee FS, Chen ZY (2011) Region- specific involvement of BDNF secretion and synthesis in conditioned taste aversion memory formation. J Neurosci 31:2079–2090
    • (2011) J Neurosci , vol.31 , pp. 2079-2090
    • Ma, L.1    Wang, D.D.2    Zhang, T.Y.3    Yu, H.4    Wang, Y.5    Huang, S.H.6    Lee, F.S.7    Chen, Z.Y.8
  • 83
    • 79952325340 scopus 로고    scopus 로고
    • Activity-dependent brain-derived neurotrophic factor expression regulates cortistatin-interneurons and sleep behavior
    • Martinowich K, Schloesser RJ, Jimenez DV, Weinberger DR, Lu B (2011a) Activity-dependent brain-derived neurotrophic factor expression regulates cortistatin-interneurons and sleep behavior. Mol Brain 4:11
    • (2011) Mol Brain , vol.4
    • Martinowich, K.1    Schloesser, R.J.2    Jimenez, D.V.3    Weinberger, D.R.4    Lu, B.5
  • 85
    • 38649128208 scopus 로고    scopus 로고
    • Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF
    • Matsumoto T, Rauskolb S, Polack M, Klose J, Kolbeck R, Korte M, Barde YA (2008) Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF. Nat Neurosci 11:131–133
    • (2008) Nat Neurosci , vol.11 , pp. 131-133
    • Matsumoto, T.1    Rauskolb, S.2    Polack, M.3    Klose, J.4    Kolbeck, R.5    Korte, M.6    Barde, Y.A.7
  • 88
    • 0034666119 scopus 로고    scopus 로고
    • Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats
    • Mizuno M, Yamada K, Olariu A, Nawa H, Nabeshima T (2000) Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats. J Neurosci 20:7116–7121
    • (2000) J Neurosci , vol.20 , pp. 7116-7121
    • Mizuno, M.1    Yamada, K.2    Olariu, A.3    Nawa, H.4    Nabeshima, T.5
  • 89
    • 34447529155 scopus 로고    scopus 로고
    • Induction of long-term memory by exposure to novelty requires protein synthesis: Evidence for a behavioral tagging
    • Moncada D, Viola H (2007) Induction of long-term memory by exposure to novelty requires protein synthesis: evidence for a behavioral tagging. J Neurosci 27:7476–7481
    • (2007) J Neurosci , vol.27 , pp. 7476-7481
    • Moncada, D.1    Viola, H.2
  • 90
    • 0032052181 scopus 로고    scopus 로고
    • Time-dependent changes in neurotrophic factor mRNA expression after kindling and long-term potentiation in rats
    • Morimoto K, Sato K, Sato S, Yamada N, Hayabara T (1998) Time-dependent changes in neurotrophic factor mRNA expression after kindling and long-term potentiation in rats. Brain Res Bull 45:599–605
    • (1998) Brain Res Bull , vol.45 , pp. 599-605
    • Morimoto, K.1    Sato, K.2    Sato, S.3    Yamada, N.4    Hayabara, T.5
  • 91
  • 92
    • 0033600503 scopus 로고    scopus 로고
    • Deprivation of endogenous brain-derived neurotrophic factor results in impairment of spatial learning and memory in adult rats
    • Mu JS, Li WP, Yao ZB, Zhou XF (1999) Deprivation of endogenous brain-derived neurotrophic factor results in impairment of spatial learning and memory in adult rats. Brain Res 835:259–265
    • (1999) Brain Res , vol.835 , pp. 259-265
    • Mu, J.S.1    Li, W.P.2    Yao, Z.B.3    Zhou, X.F.4
  • 94
    • 77954421126 scopus 로고    scopus 로고
    • The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus
    • Ninan I, Bath KG, Dagar K, Perez-Castro R, Plummer MR, Lee FS, Chao MV (2010) The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus. J Neurosci 30:8866–8870
    • (2010) J Neurosci , vol.30 , pp. 8866-8870
    • Ninan, I.1    Bath, K.G.2    Dagar, K.3    Perez-Castro, R.4    Plummer, M.R.5    Lee, F.S.6    Chao, M.V.7
  • 95
    • 0942263512 scopus 로고    scopus 로고
    • Modulation of cortical excitability by weak direct current stimulation – technical, safety and functional aspects
    • Nitsche MA, Liebetanz D, Antal A, Lang N, Tergau F, Paulus W (2003) Modulation of cortical excitability by weak direct current stimulation – technical, safety and functional aspects. Suppl Clin Neurophysiol 56:255–276
    • (2003) Suppl Clin Neurophysiol , vol.56 , pp. 255-276
    • Nitsche, M.A.1    Liebetanz, D.2    Antal, A.3    Lang, N.4    Tergau, F.5    Paulus, W.6
  • 97
    • 0034669053 scopus 로고    scopus 로고
    • Increased synaptic inhibition in dentate gyrus of mice with reduced levels of endogenous brain-derived neurotrophic factor
    • Olofsdotter K, Lindvall O, Asztely F (2000) Increased synaptic inhibition in dentate gyrus of mice with reduced levels of endogenous brain-derived neurotrophic factor. Neuroscience 101:531–539
    • (2000) Neuroscience , vol.101 , pp. 531-539
    • Olofsdotter, K.1    Lindvall, O.2    Asztely, F.3
  • 99
    • 0027075042 scopus 로고
    • Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs
    • Patterson SL, Grover LM, Schwartzkroin PA, Bothwell M (1992) Neurotrophin expression in rat hippocampal slices: a stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs. Neuron 9:1081–1088
    • (1992) Neuron , vol.9 , pp. 1081-1088
    • Patterson, S.L.1    Grover, L.M.2    Schwartzkroin, P.A.3    Bothwell, M.4
  • 100
    • 0030176079 scopus 로고    scopus 로고
    • Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice
    • Patterson SL, Abel T, Deuel TA, Martin KC, Rose JC, Kandel ER (1996) Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron 16:1137–1145
    • (1996) Neuron , vol.16 , pp. 1137-1145
    • Patterson, S.L.1    Abel, T.2    Deuel, T.A.3    Martin, K.C.4    Rose, J.C.5    Kandel, E.R.6
  • 101
    • 0034773788 scopus 로고    scopus 로고
    • Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase
    • Patterson SL, Pittenger C, Morozov A, Martin KC, Scanlin H, Drake C, Kandel ER (2001) Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase. Neuron 32:123–140
    • (2001) Neuron , vol.32 , pp. 123-140
    • Patterson, S.L.1    Pittenger, C.2    Morozov, A.3    Martin, K.C.4    Scanlin, H.5    Drake, C.6    Kandel, E.R.7
  • 102
  • 104
    • 34547499702 scopus 로고    scopus 로고
    • Dissecting the human BDNF locus: Bidirectional transcription, complex splicing, and multiple promoters
    • Pruunsild P, Kazantseva A, Aid T, Palm K, Timmusk T (2007) Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters. Genomics 90:397–406
    • (2007) Genomics , vol.90 , pp. 397-406
    • Pruunsild, P.1    Kazantseva, A.2    Aid, T.3    Palm, K.4    Timmusk, T.5
  • 105
    • 79957598473 scopus 로고    scopus 로고
    • In neurons, activitydependent association of dendritically transported mRNA transcripts with the transacting factor CBF-A is mediated by A2RE/RTS elements
    • Raju CS, Fukuda N, Lopez-Iglesias C, Goritz C, Visa N, Percipalle P (2011) In neurons, activitydependent association of dendritically transported mRNA transcripts with the transacting factor CBF-A is mediated by A2RE/RTS elements. Mol Biol Cell 22:1864–1877
    • (2011) Mol Biol Cell , vol.22 , pp. 1864-1877
    • Raju, C.S.1    Fukuda, N.2    Lopez-Iglesias, C.3    Goritz, C.4    Visa, N.5    Percipalle, P.6
  • 107
    • 0034192397 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF) induces dendritic targeting of BDNF and tyrosine kinase B mRNAs in hippocampal neurons through a phosphatidylinositol-3 kinase-dependent pathway
    • Righi M, Tongiorgi E, Cattaneo A (2000) Brain-derived neurotrophic factor (BDNF) induces dendritic targeting of BDNF and tyrosine kinase B mRNAs in hippocampal neurons through a phosphatidylinositol-3 kinase-dependent pathway. J Neurosci 20:3165–3174
    • (2000) J Neurosci , vol.20 , pp. 3165-3174
    • Righi, M.1    Tongiorgi, E.2    Cattaneo, A.3
  • 109
    • 18844402387 scopus 로고    scopus 로고
    • The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus
    • Rosch H, Schweigreiter R, Bonhoeffer T, Barde YA, Korte M (2005) The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus. Proc Natl Acad Sci U S A 102:7362–7367
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 7362-7367
    • Rosch, H.1    Schweigreiter, R.2    Bonhoeffer, T.3    Barde, Y.A.4    Korte, M.5
  • 110
    • 0033847296 scopus 로고    scopus 로고
    • Transgenic mice overexpressing truncated trkB neurotrophin receptors in neurons have impaired long-term spatial memory but normal hippocampal LTP
    • Saarelainen T, Pussinen R, Koponen E, Alhonen L, Wong G, Sirvio J, Castren E (2000) Transgenic mice overexpressing truncated trkB neurotrophin receptors in neurons have impaired long-term spatial memory but normal hippocampal LTP. Synapse 38:102–104
    • (2000) Synapse , vol.38 , pp. 102-104
    • Saarelainen, T.1    Pussinen, R.2    Koponen, E.3    Alhonen, L.4    Wong, G.5    Sirvio, J.6    Castren, E.7
  • 111
    • 65249121931 scopus 로고    scopus 로고
    • Critical role of promoter IV-driven BDNF transcription in GABAergic transmission and synaptic plasticity in the prefrontal cortex
    • Sakata K, Woo NH, Martinowich K, Greene JS, Schloesser RJ, Shen L, Lu B (2009) Critical role of promoter IV-driven BDNF transcription in GABAergic transmission and synaptic plasticity in the prefrontal cortex. Proc Natl Acad Sci U S A 106:5942–5947
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 5942-5947
    • Sakata, K.1    Woo, N.H.2    Martinowich, K.3    Greene, J.S.4    Schloesser, R.J.5    Shen, L.6    Lu, B.7
  • 112
    • 0036334172 scopus 로고    scopus 로고
    • Dendritic targeting of mRNAs for plasticity genes in experimental models of temporal lobe epilepsy
    • Simonato M, Bregola G, Armellin M, Del Piccolo P, Rodi D, Zucchini S, Tongiorgi E (2002) Dendritic targeting of mRNAs for plasticity genes in experimental models of temporal lobe epilepsy. Epilepsia 43(Suppl 5):153–158
    • (2002) Epilepsia , vol.43 , pp. 153-158
    • Simonato, M.1    Bregola, G.2    Armellin, M.3    Del Piccolo, P.4    Rodi, D.5    Zucchini, S.6    Tongiorgi, E.7
  • 113
    • 0028969330 scopus 로고
    • Visual feature integration and the temporal correlation hypothesis
    • Singer W, Gray CM (1995) Visual feature integration and the temporal correlation hypothesis. Annu Rev Neurosci 18:555–586
    • (1995) Annu Rev Neurosci , vol.18 , pp. 555-586
    • Singer, W.1    Gray, C.M.2
  • 114
    • 0034708738 scopus 로고    scopus 로고
    • Down-regulation of the neurotrophin receptor TrkB following ligand binding. Evidence for an involvement of the proteasome and differential regulation of TrkA and TrkB
    • Sommerfeld MT, Schweigreiter R, Barde YA, Hoppe E (2000) Down-regulation of the neurotrophin receptor TrkB following ligand binding. Evidence for an involvement of the proteasome and differential regulation of TrkA and TrkB. J Biol Chem 275:8982–8990
    • (2000) J Biol Chem , vol.275 , pp. 8982-8990
    • Sommerfeld, M.T.1    Schweigreiter, R.2    Barde, Y.A.3    Hoppe, E.4
  • 118
    • 0032892612 scopus 로고    scopus 로고
    • Oscillatory gamma activity in humans and its role in object representation
    • Tallon-Baudry C, Bertrand O (1999) Oscillatory gamma activity in humans and its role in object representation. Trends Cogn Sci 3:151–162
    • (1999) Trends Cogn Sci , vol.3 , pp. 151-162
    • Tallon-Baudry, C.1    Bertrand, O.2
  • 119
    • 0030612039 scopus 로고    scopus 로고
    • Inhibition of GABAA synaptic responses by brain-derived neurotrophic factor (BDNF) in rat hippocampus
    • Tanaka T, Saito H, Matsuki N (1997) Inhibition of GABAA synaptic responses by brain-derived neurotrophic factor (BDNF) in rat hippocampus. J Neurosci 17:2959–2966
    • (1997) J Neurosci , vol.17 , pp. 2959-2966
    • Tanaka, T.1    Saito, H.2    Matsuki, N.3
  • 122
    • 0031439983 scopus 로고    scopus 로고
    • Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons
    • Tongiorgi E, Righi M, Cattaneo A (1997) Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons. J Neurosci 17:9492–9505
    • (1997) J Neurosci , vol.17 , pp. 9492-9505
    • Tongiorgi, E.1    Righi, M.2    Cattaneo, A.3
  • 125
    • 33748978944 scopus 로고    scopus 로고
    • Noninvasive brain stimulation in stroke rehabilitation
    • Webster BR, Celnik PA, Cohen LG (2006) Noninvasive brain stimulation in stroke rehabilitation. NeuroRx 3:474–481
    • (2006) Neurorx , vol.3 , pp. 474-481
    • Webster, B.R.1    Celnik, P.A.2    Cohen, L.G.3
  • 127
    • 3242740072 scopus 로고    scopus 로고
    • Differences in spatial learning comparing transgenic p75 knockout, New Zealand Black, C57BL/6, and Swiss Webster mice
    • Wright JW, Alt JA, Turner GD, Krueger JM (2004) Differences in spatial learning comparing transgenic p75 knockout, New Zealand Black, C57BL/6, and Swiss Webster mice. Behav Brain Res 153:453–458
    • (2004) Behav Brain Res , vol.153 , pp. 453-458
    • Wright, J.W.1    Alt, J.A.2    Turner, G.D.3    Krueger, J.M.4
  • 128
    • 0031034679 scopus 로고    scopus 로고
    • Tyrosine kinase receptors concentrated in caveolaelike domains from neuronal plasma membrane
    • Wu C, Butz S, Ying Y, Anderson RG (1997) Tyrosine kinase receptors concentrated in caveolaelike domains from neuronal plasma membrane. J Biol Chem 272:3554–3559
    • (1997) J Biol Chem , vol.272 , pp. 3554-3559
    • Wu, C.1    Butz, S.2    Ying, Y.3    Erson, R.G.4
  • 129
    • 78149248751 scopus 로고    scopus 로고
    • Genome- wide analysis reveals methyl-CpG-binding protein 2-dependent regulation of microRNAs in a mouse model of Rett syndrome
    • Wu H, Tao J, Chen PJ, Shahab A, Ge W, Hart RP, Ruan X, Ruan Y, Sun YE (2010) Genome- wide analysis reveals methyl-CpG-binding protein 2-dependent regulation of microRNAs in a mouse model of Rett syndrome. Proc Natl Acad Sci U S A 107:18161–18166
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 18161-18166
    • Wu, H.1    Tao, J.2    Chen, P.J.3    Shahab, A.4    Ge, W.5    Hart, R.P.6    Ruan, X.7    Ruan, Y.8    Sun, Y.E.9
  • 130
    • 79952442835 scopus 로고    scopus 로고
    • Dendritic trafficking of brain-derived neurotrophic factor mRNA: Regulation by translindependent and -independent mechanisms
    • Wu YC, Williamson R, Li Z, Vicario A, Xu J, Kasai M, Chern Y, Tongiorgi E, Baraban JM (2011) Dendritic trafficking of brain-derived neurotrophic factor mRNA: regulation by translindependent and -independent mechanisms. J Neurochem 116:1112–1121
    • (2011) J Neurochem , vol.116 , pp. 1112-1121
    • Wu, Y.C.1    Williamson, R.2    Li, Z.3    Vicario, A.4    Xu, J.5    Kasai, M.6    Chern, Y.7    Tongiorgi, E.8    Baraban, J.M.9
  • 131
    • 79954459377 scopus 로고    scopus 로고
    • Endogenous proBDNF is a negative regulator of migration of cerebellar granule cells in neonatal mice
    • Xu ZQ, Sun Y, Li HY, Lim Y, Zhong JH, Zhou XF (2011) Endogenous proBDNF is a negative regulator of migration of cerebellar granule cells in neonatal mice. Eur J Neurosci 33:1376–1384
    • (2011) Eur J Neurosci , vol.33 , pp. 1376-1384
    • Xu, Z.Q.1    Sun, Y.2    Li, H.Y.3    Lim, Y.4    Zhong, J.H.5    Zhou, X.F.6
  • 132
    • 66149128363 scopus 로고    scopus 로고
    • Pro-BDNF-induced synaptic depression and retraction at developing neuromuscular synapses
    • Yang F, Je HS, Ji Y, Nagappan G, Hempstead B, Lu B (2009a) Pro-BDNF-induced synaptic depression and retraction at developing neuromuscular synapses. J Cell Biol 185:727–741
    • (2009) J Cell Biol , vol.185 , pp. 727-741
    • Yang, F.1    Je, H.S.2    Ji, Y.3    Nagappan, G.4    Hempstead, B.5    Lu, B.6
  • 134
    • 0033776498 scopus 로고    scopus 로고
    • Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1
    • York RD, Molliver DC, Grewal SS, Stenberg PE, McCleskey EW, Stork PJ (2000) Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1. Mol Cell Biol 20:8069–8083
    • (2000) Mol Cell Biol , vol.20 , pp. 8069-8083
    • York, R.D.1    Molliver, D.C.2    Grewal, S.S.3    Stenberg, P.E.4    McCleskey, E.W.5    Stork, P.J.6
  • 135
    • 0034255428 scopus 로고    scopus 로고
    • Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation
    • Zhang Y, Moheban DB, Conway BR, Bhattacharyya A, Segal RA (2000) Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation. J Neurosci 20:5671–5678
    • (2000) J Neurosci , vol.20 , pp. 5671-5678
    • Zhang, Y.1    Moheban, D.B.2    Conway, B.R.3    Bhattacharyya, A.4    Segal, R.A.5
  • 136
    • 80054717401 scopus 로고    scopus 로고
    • TrkB signaling in parvalbumin-positive interneurons is critical for gamma-band network synchronization in hippocampus
    • Zheng K, An JJ, Yang F, Xu W, Xu ZQ, Wu J, Hokfelt TG, Fisahn A, Xu B, Lu B (2011) TrkB signaling in parvalbumin-positive interneurons is critical for gamma-band network synchronization in hippocampus. Proc Natl Acad Sci U S A 108:17201–17206
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 17201-17206
    • Zheng, K.1    An, J.J.2    Yang, F.3    Xu, W.4    Xu, Z.Q.5    Wu, J.6    Hokfelt, T.G.7    Fisahn, A.8    Xu, B.9    Lu, B.10
  • 138
    • 23044515099 scopus 로고    scopus 로고
    • Functions and mechanisms of retrograde neurotrophin signalling
    • Zweifel LS, Kuruvilla R, Ginty DD (2005) Functions and mechanisms of retrograde neurotrophin signalling. Nat Rev Neurosci 6:615–625
    • (2005) Nat Rev Neurosci , vol.6 , pp. 615-625
    • Zweifel, L.S.1    Kuruvilla, R.2    Ginty, D.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.