Functions and Mechanisms of BDNF mRNA Trafficking

Growth Factors and Psychiatric Disorders

Volumn 289, Issue , 2008, Pages 136-147

  Tongiorgi, Enrico ^a   Baj, Gabriele ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

Author keywords

Basket parvalbuminergic cells; Brain derived neurotrophic factor (BDNF); Green fluorescent protein (GFP) reporter gene; Intrinsic hippocampal glutamatergic fibre; Unstimulated hippocampal neurons

Indexed keywords

EID: 85051051018     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470751251.ch11     Document Type: Chapter

References (36)

1. Aid T, Kazantseva A, Piirsoo M, Palm K, Timmusk T 2007 Mouse and rat BDNF gene structure and expression revisited. J Neurosci Res 15:525-535.
2. Bramham CR, Messaoudi E 2005 BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis. Prog Neurobiol 76:99-125.
3. Capsoni S, Tongiorgi E, Cattaneo A, Domenici L 1999 Differential regulation of brain-derived neurotrophic factor mRNA cellular expression in the adult rat visual cortex. Neuroscience 93:1033-1040.
4. Castren E 2004 Neurotrophic effects of antidepressant drugs. Curr Opin Pharmacol 4:58-64.
5. Chao MV, Rajagopal R, Lee FS 2006 Neurotrophin signalling in health and disease. Clin Sci (Lond) 110:167-173.
6. Conner JM, Lauterborn JC, Yan Q, Gall CM, Varon S 1997 Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: evidence for anterograde axonal transport. J Neurosci 17:2295-2310.
7. Dias BG, Banerjee SB, Duman RS, Vaidya VA 2003 Differential regulation of brain derived neurotrophic factor transcripts by antidepressant treatments in the adult rat brain. Neuropharmacology 45:553-563.
8. Eberwine J, Belt B, Kacharmina JE, Miyashiro K 2002 Analysis of subcellularly localized mRNAs using in situ hybridization, mRNA amplification, and expression profiling. Neurochem Res 27:1065-1077.
9. Egan MF, Kojima M, Callicott JH et al 2003 The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 112:257-269.
10. Giuditta A, Menichini E, Perrone Capano C et al 1991 Active polysomes in the axoplasm of the squid giant axon. J Neurosci Res 28:18-28.
11. Horch HW, Katz LC 2002 BDNF release from single cells elicits local dendritic growth in nearby neurons. Nat Neurosci 5:1177-1184.
12. Kanai Y, Dohmae N, Hirokawa N 2004 Kinesin transports RNA: isolation and characterization of an RNA-transporting granule. Neuron 43:513-525.
13. Kang H, Schuman EM 1996 A requirement for local protein synthesis in neurotrophin-induced hippocampal synaptic plasticity. Science 6:1402-1406.
14. Kloc M, Zearfoss NR, Etkin LD 2002 Mechanisms of subcellular mRNA localization. Cell 108:533-544.
15. Krichevsky AM, Kosik KS 2001 Neuronal RNA granules: a link between RNA localization and stimulation-dependent translation. Neuron 32:683-696.
16. Liu QR, Walther D, Drgon T et al 2005 Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's Disease. Am J Med Genet B Neuropsychiatr Genet 134:93-103.
17. Liu QR, Lu L, Zhu XG, Gong JP, Shaham Y, Uhl GR 2006 Rodent BDNF genes, novel promoters, novel splice varicants, and regulation by cocaine. Brain Res 1067:1-12.
18. Molnar M, Tongiorgi E, Avignone E et al 1998 The effects of anti-nerve growth factor monoclonal antibodies on developing basal forebrain neurons are transient and reversible. Eur J Neurosci 10:3127-3140.
19. Mowla SJ, Farhadi HF, Pareek S et al 2001 Biosynthesis and post-translational processing of the precursor to brain derived neurotrophic factor. J Biol Chem 276:12660-12666.
20. Nguyen PV, Abel T, Kandel ER 1994 Requirement of a critical period of transcription for induction of a late phase of LTP. Science 265:1104-1107.
21. Pang PT, Teng HK, Zaitsev E et al 2004 Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity. Science 15:487-491.
22. Pattabiraman PP, Tropea D, Chiaruttini C, Tongiorgi E, Cattaneo A, Domenici L 2005 Neuronal activity regulates the developmental expression and subcellular localization of cortical BDNF mRNA isoforms in vivo. Mol Cell Neurosci 28:556-570.
23. Reymann KG, Frey JU 2007 The late maintenance of hippocampal LTP: requirements, phases, 'synaptic tagging', 'late-associativity' and implications. Neuropharmacology 52:24-40.
24. Righi M, Tongiorgi E, Cattaneo A 2000 Brain-derived neurotrophic factor (BDNF) induces dendritic targeting of BDNF and tyrosine kinase B mRNAs in hippocampal neurons through a phosphatidylinositol-3 kinase-dependent pathway. J Neurosci 1:3165-3174.
25. Simonato M, Bregola G, Armellin M et al 2002 Dendritic targeting of mRNAs for plasticity genes in experimental models of temporal lobe epilepsy. Epilepsia 43:153-158.
26. Steward O, Levy WB 1982 Preferential localization of polyribosomes under the base of dendritic spines in granule cells of the dentate gyrus. J Neurosci 2:284-291.
27. Steward O, Schuman EM 2001 Protein synthesis at synaptic sites on dendrites. Annu Rev Neurosci 24:299-325.
28. Steward O, Wallace CS, Lyford GL, Worley PF 1998 Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites. Neuron 21:741-751.
29. Sutton MA, Schuman EM 2005 Local translational control in dendrites and its role in long-term synaptic plasticity. J Neurobiol 64:116-131.
30. Tongiorgi E, Righi M, Cattaneo A 1997 Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neuorons. J Neurosci 17:9492-9505.
31. Tongiorgi E, Armellin M, Cattaneo A 2000 Differential somato-dendritic localization of TrkA, TrkB, TrkC and p75 mRNAs in vivo. Neuroreport 28:3265-3268.
32. Tongiorgi E, Armellin M, Giulianini PG et al 2004 BDNF mRNA and protein are targeted to discrete dendritic laminae by events that trigger epileptogenesis. J Neurosci 30:6842-6852.
33. Tongiorgi E, Domenici L, Simonato M 2006 What is the biological significance of BDNF mRNA targeting in the dendrites? Clues from epilepsy and cortical development. Mol Neurobiol 33:17-32.
34. Willemsen R, Oostra BA, Bassell GJ, Dictenberg J 2004 The fragile X syndrome: from molecular genetics to neurobiology. Ment Retard Dev Disabil Res Rev 10:60-67.
35. Zafra F, Hengerer B, Leibrock J, Thoenen H, Lindholm D 1990 Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J 9:3545-3550.
36. Zhong J, Zhang T, Bloch LM 2006 Dendritic mRNAs encode diversified functionalities in hippocampal pyramidal neurons. BMC Neurosci 7:7.