메뉴 건너뛰기




Volumn 26, Issue 1, 2004, Pages 166-181

Transgenic mice overexpressing the full-length neurotrophin receptor trkB exhibit increased activation of the trkB-PLCγ pathway, reduced anxiety, and facilitated learning

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C; PHOSPHOLIPASE CGAMMA; PROTEIN SHC; UNCLASSIFIED DRUG;

EID: 2342472745     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2004.01.006     Document Type: Article
Times cited : (155)

References (90)
  • 1
    • 0028866034 scopus 로고
    • Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice
    • Aigner L., Arber S., Kapfhammer J.P., Laux T., Schneider C., Botteri F., Brenner H.R., Caroni P. Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice. Cell. 83:1995;269-278
    • (1995) Cell , vol.83 , pp. 269-278
    • Aigner, L.1    Arber, S.2    Kapfhammer, J.P.3    Laux, T.4    Schneider, C.5    Botteri, F.6    Brenner, H.R.7    Caroni, P.8
  • 3
    • 0030995057 scopus 로고    scopus 로고
    • TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death
    • Alcantara S., Frisen J., del Rio J.A., Soriano E., Barbacid M., Silos-Santiago I. TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death. J. Neurosci. 17:1997;3623-3633
    • (1997) J. Neurosci. , vol.17 , pp. 3623-3633
    • Alcantara, S.1    Frisen, J.2    Del Rio, J.A.3    Soriano, E.4    Barbacid, M.5    Silos-Santiago, I.6
  • 4
    • 0032876611 scopus 로고    scopus 로고
    • Activity-dependent activation of TrkB neurotrophin receptors in the adult CNS
    • Aloyz R., Fawcett J.P., Kaplan D.R., Murphy R.A., Miller F.D. Activity-dependent activation of TrkB neurotrophin receptors in the adult CNS. Learn Mem. 6:1999;216-231
    • (1999) Learn Mem. , vol.6 , pp. 216-231
    • Aloyz, R.1    Fawcett, J.P.2    Kaplan, D.R.3    Murphy, R.A.4    Miller, F.D.5
  • 5
    • 0035878799 scopus 로고    scopus 로고
    • The LTP Program: A data acquisition program for on-line analysis of long-term potentiation and other synaptic events
    • Anderson W.W., Collingridge G.L. The LTP Program: a data acquisition program for on-line analysis of long-term potentiation and other synaptic events. J. Neurosci. Methods. 108:2001;71-83
    • (2001) J. Neurosci. Methods , vol.108 , pp. 71-83
    • Anderson, W.W.1    Collingridge, G.L.2
  • 7
    • 0036895965 scopus 로고    scopus 로고
    • Heterozygous knock-out mice for brain-derived neurotrophic factor show a pathway-specific impairment of long-term potentiation but normal critical period for monocular deprivation
    • Bartoletti A., Cancedda L., Reid S.W., Tessarollo L., Porciatti V., Pizzorusso T., Maffei L. Heterozygous knock-out mice for brain-derived neurotrophic factor show a pathway-specific impairment of long-term potentiation but normal critical period for monocular deprivation. J. Neurosci. 22:2002;10072-10077
    • (2002) J. Neurosci. , vol.22 , pp. 10072-10077
    • Bartoletti, A.1    Cancedda, L.2    Reid, S.W.3    Tessarollo, L.4    Porciatti, V.5    Pizzorusso, T.6    Maffei, L.7
  • 9
    • 0028916394 scopus 로고
    • Functional interactions of neurotrophins and neurotrophin receptors
    • Bothwell M. Functional interactions of neurotrophins and neurotrophin receptors. Annu. Rev. Neurosci. 18:1995;223-253
    • (1995) Annu. Rev. Neurosci. , vol.18 , pp. 223-253
    • Bothwell, M.1
  • 12
    • 0033568871 scopus 로고    scopus 로고
    • Relative contribution of endogenous neurotrophins in hippocampal long-term potentiation
    • Chen G., Kolbeck R., Barde Y.A., Bonhoeffer T., Kossel A. Relative contribution of endogenous neurotrophins in hippocampal long-term potentiation. J. Neurosci. 19:1999;7983-7990
    • (1999) J. Neurosci. , vol.19 , pp. 7983-7990
    • Chen, G.1    Kolbeck, R.2    Barde, Y.A.3    Bonhoeffer, T.4    Kossel, A.5
  • 13
    • 0035076192 scopus 로고    scopus 로고
    • Sustained signaling by phospholipase C-gamma mediates nerve growth factor-triggered gene expression
    • Choi D.Y., Toledo-Aral J.J., Segal R., Halegoua S. Sustained signaling by phospholipase C-gamma mediates nerve growth factor-triggered gene expression. Mol. Cell. Biol. 21:2001;2695-2705
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 2695-2705
    • Choi, D.Y.1    Toledo-Aral, J.J.2    Segal, R.3    Halegoua, S.4
  • 16
    • 0032765275 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex
    • Croll S.D., Suri C., Compton D.L., Simmons M.V., Yancopoulos G.D., Lindsay R.M., Wiegand S.J., Rudge J.S., Scharfman H.E. Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex. Neuroscience. 93:1999;1491-1506
    • (1999) Neuroscience , vol.93 , pp. 1491-1506
    • Croll, S.D.1    Suri, C.2    Compton, D.L.3    Simmons, M.V.4    Yancopoulos, G.D.5    Lindsay, R.M.6    Wiegand, S.J.7    Rudge, J.S.8    Scharfman, H.E.9
  • 17
    • 0030919664 scopus 로고    scopus 로고
    • Heterogeneity of release probability, facilitation, and depletion at central synapses
    • Dobrunz L.E., Stevens C.F. Heterogeneity of release probability, facilitation, and depletion at central synapses. Neuron. 18:1997;995-1008
    • (1997) Neuron , vol.18 , pp. 995-1008
    • Dobrunz, L.E.1    Stevens, C.F.2
  • 18
    • 0033567457 scopus 로고    scopus 로고
    • Ultrastructural localization of full-length trkB immunoreactivity in rat hippocampus suggests multiple roles in modulating activity-dependent synaptic plasticity
    • Drake C.T., Milner T.A., Patterson S.L. Ultrastructural localization of full-length trkB immunoreactivity in rat hippocampus suggests multiple roles in modulating activity-dependent synaptic plasticity. J. Neurosci. 19:1999;8009-8026
    • (1999) J. Neurosci. , vol.19 , pp. 8009-8026
    • Drake, C.T.1    Milner, T.A.2    Patterson, S.L.3
  • 20
    • 0028274040 scopus 로고
    • Mice lacking brain-derived neurotrophic factor develop with sensory deficits
    • Ernfors P., Lee K.F., Jaenisch R. Mice lacking brain-derived neurotrophic factor develop with sensory deficits. Nature. 368:1994;147-150
    • (1994) Nature , vol.368 , pp. 147-150
    • Ernfors, P.1    Lee, K.F.2    Jaenisch, R.3
  • 21
    • 0026589752 scopus 로고
    • Increased expression of brain-derived neurotrophic factor mRNA in rat hippocampus is associated with improved spatial memory and enriched environment
    • Falkenberg T., Mohammed A.K., Henriksson B., Persson H., Winblad B., Lindefors N. Increased expression of brain-derived neurotrophic factor mRNA in rat hippocampus is associated with improved spatial memory and enriched environment. Neurosci. Lett. 138:1992;153-156
    • (1992) Neurosci. Lett. , vol.138 , pp. 153-156
    • Falkenberg, T.1    Mohammed, A.K.2    Henriksson, B.3    Persson, H.4    Winblad, B.5    Lindefors, N.6
  • 23
    • 0029970008 scopus 로고    scopus 로고
    • Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus
    • Figurov A., Pozzo-Miller L.D., Olafsson P., Wang T., Lu B. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature. 381:1996;706-709
    • (1996) Nature , vol.381 , pp. 706-709
    • Figurov, A.1    Pozzo-Miller, L.D.2    Olafsson, P.3    Wang, T.4    Lu, B.5
  • 24
    • 0034281379 scopus 로고    scopus 로고
    • Superior water maze performance and increase in fear-related behavior in the endothelial nitric oxide synthase-deficient mouse together with monoamine changes in cerebellum and ventral striatum
    • Frisch C., Dere E., Silva M.A., Godecke A., Schrader J., Huston J.P. Superior water maze performance and increase in fear-related behavior in the endothelial nitric oxide synthase-deficient mouse together with monoamine changes in cerebellum and ventral striatum. J. Neurosci. 20:2000;6694-6700
    • (2000) J. Neurosci. , vol.20 , pp. 6694-6700
    • Frisch, C.1    Dere, E.2    Silva, M.A.3    Godecke, A.4    Schrader, J.5    Huston, J.P.6
  • 26
    • 0035875794 scopus 로고    scopus 로고
    • Spatial learning induces neurotrophin receptor and synapsin I in the hippocampus
    • Gomez-Pinilla F., So V., Kesslak J.P. Spatial learning induces neurotrophin receptor and synapsin I in the hippocampus. Brain Res. 904:2001;13-19
    • (2001) Brain Res. , vol.904 , pp. 13-19
    • Gomez-Pinilla, F.1    So, V.2    Kesslak, J.P.3
  • 27
    • 0036759632 scopus 로고    scopus 로고
    • Immunohistochemical evidence of seizure-induced activation of trkB receptors in the mossy fiber pathway of adult mouse hippocampus
    • He X.P., Minichiello L., Klein R., McNamara J.O. Immunohistochemical evidence of seizure-induced activation of trkB receptors in the mossy fiber pathway of adult mouse hippocampus. J. Neurosci. 22:2002;7502-7508
    • (2002) J. Neurosci. , vol.22 , pp. 7502-7508
    • He, X.P.1    Minichiello, L.2    Klein, R.3    McNamara, J.O.4
  • 28
    • 0025279814 scopus 로고
    • Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain
    • Hofer M., Pagliusi S.R., Hohn A., Leibrock J., Barde Y.A. Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain. EMBO J. 9:1990;2459-2464
    • (1990) EMBO J. , vol.9 , pp. 2459-2464
    • Hofer, M.1    Pagliusi, S.R.2    Hohn, A.3    Leibrock, J.4    Barde, Y.A.5
  • 29
    • 0034927081 scopus 로고    scopus 로고
    • Neurotrophins: Roles in neuronal development and function
    • Huang E.J., Reichardt L.F. Neurotrophins: roles in neuronal development and function. Annu. Rev. Neurosci. 24:2001;677-736
    • (2001) Annu. Rev. Neurosci. , vol.24 , pp. 677-736
    • Huang, E.J.1    Reichardt, L.F.2
  • 30
    • 0345585441 scopus 로고    scopus 로고
    • TRK receptors: Roles in neuronal signal transduction
    • Huang E.J., Reichardt L.F. TRK receptors: roles in neuronal signal transduction. Annu. Rev. Biochem. 27:2003;27
    • (2003) Annu. Rev. Biochem. , vol.27 , pp. 27
    • Huang, E.J.1    Reichardt, L.F.2
  • 31
    • 0022765970 scopus 로고
    • Characterization of two atypical promoters and alternate mRNA processing in the mouse Thy-1.2 glycoprotein gene
    • Ingraham H.A., Evans G.A. Characterization of two atypical promoters and alternate mRNA processing in the mouse Thy-1.2 glycoprotein gene. Mol. Cell. Biol. 6:1986;2923-2931
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 2923-2931
    • Ingraham, H.A.1    Evans, G.A.2
  • 32
    • 0028351190 scopus 로고
    • Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development
    • Jones K.R., Farinas I., Backus C., Reichardt L.F. Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development. Cell. 76:1994;989-999
    • (1994) Cell , vol.76 , pp. 989-999
    • Jones, K.R.1    Farinas, I.2    Backus, C.3    Reichardt, L.F.4
  • 34
    • 0030967828 scopus 로고    scopus 로고
    • Neurotrophins and time: Different roles for TrkB signaling in hippocampal long-term potentiation
    • Kang H., Welcher A.A., Shelton D., Schuman E.M. Neurotrophins and time: different roles for TrkB signaling in hippocampal long-term potentiation. Neuron. 19:1997;653-664
    • (1997) Neuron , vol.19 , pp. 653-664
    • Kang, H.1    Welcher, A.A.2    Shelton, D.3    Schuman, E.M.4
  • 35
    • 0034044227 scopus 로고    scopus 로고
    • Neurotrophin signal transduction in the nervous system
    • Kaplan D.R., Miller F.D. Neurotrophin signal transduction in the nervous system. Curr. Opin. Neurobiol. 10:2000;381-391
    • (2000) Curr. Opin. Neurobiol. , vol.10 , pp. 381-391
    • Kaplan, D.R.1    Miller, F.D.2
  • 37
    • 0031656199 scopus 로고    scopus 로고
    • Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: A mechanism to facilitate encoding and circuit maintenance?
    • Kesslak J.P., So V., Choi J., Cotman C.W., Gomez-Pinilla F. Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: a mechanism to facilitate encoding and circuit maintenance? Behav. Neurosci. 112:1998;1012-1019
    • (1998) Behav. Neurosci. , vol.112 , pp. 1012-1019
    • Kesslak, J.P.1    So, V.2    Choi, J.3    Cotman, C.W.4    Gomez-Pinilla, F.5
  • 38
    • 0025100560 scopus 로고
    • Expression of the tyrosine kinase receptor gene trkB is confined to the murine embryonic and adult nervous system
    • Klein R., Martin-Zanca D., Barbacid M., Parada L.F. Expression of the tyrosine kinase receptor gene trkB is confined to the murine embryonic and adult nervous system. Development. 109:1990;845-850
    • (1990) Development , vol.109 , pp. 845-850
    • Klein, R.1    Martin-Zanca, D.2    Barbacid, M.3    Parada, L.F.4
  • 39
    • 0027491104 scopus 로고
    • Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death
    • Klein R., Smeyne R.J., Wurst W., Long L.K., Auerbach B.A., Joyner A.L., Barbacid M. Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death. Cell. 75:1993;113-122
    • (1993) Cell , vol.75 , pp. 113-122
    • Klein, R.1    Smeyne, R.J.2    Wurst, W.3    Long, L.K.4    Auerbach, B.A.5    Joyner, A.L.6    Barbacid, M.7
  • 43
    • 0029910815 scopus 로고    scopus 로고
    • Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice
    • Korte M., Griesbeck O., Gravel C., Carroll P., Staiger V., Thoenen H., Bonhoeffer T. Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice. Proc. Natl. Acad. Sci. U. S. A. 93:1996;12547-12552
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 12547-12552
    • Korte, M.1    Griesbeck, O.2    Gravel, C.3    Carroll, P.4    Staiger, V.5    Thoenen, H.6    Bonhoeffer, T.7
  • 44
    • 0033967234 scopus 로고    scopus 로고
    • Shc-binding site in the TrkB receptor is not required for hippocampal long-term potentiation
    • Korte M., Minichiello L., Klein R., Bonhoeffer T. Shc-binding site in the TrkB receptor is not required for hippocampal long-term potentiation. Neuropharmacology. 39:2000;717-724
    • (2000) Neuropharmacology , vol.39 , pp. 717-724
    • Korte, M.1    Minichiello, L.2    Klein, R.3    Bonhoeffer, T.4
  • 48
    • 0342546629 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor antisense oligonucleotide impairs memory retention and inhibits long-term potentiation in rats
    • Ma Y.L., Wang H.L., Wu H.C., Wei C.L., Lee E.H. Brain-derived neurotrophic factor antisense oligonucleotide impairs memory retention and inhibits long-term potentiation in rats. Neuroscience. 82:1998;957-967
    • (1998) Neuroscience , vol.82 , pp. 957-967
    • Ma, Y.L.1    Wang, H.L.2    Wu, H.C.3    Wei, C.L.4    Lee, E.H.5
  • 49
    • 0034801530 scopus 로고    scopus 로고
    • Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression
    • MacQueen G.M., Ramakrishnan K., Croll S.D., Siuciak J.A., Yu G., Young L.T., Fahnestock M. Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression. Behav. Neurosci. 115:2001;1145-1153
    • (2001) Behav. Neurosci. , vol.115 , pp. 1145-1153
    • MacQueen, G.M.1    Ramakrishnan, K.2    Croll, S.D.3    Siuciak, J.A.4    Yu, G.5    Young, L.T.6    Fahnestock, M.7
  • 51
    • 0036759627 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor triggers transcription-dependent, late phase long-term potentiation in vivo
    • Messaoudi E., Ying S.W., Kanhema T., Croll S.D., Bramham C.R. Brain-derived neurotrophic factor triggers transcription-dependent, late phase long-term potentiation in vivo. J. Neurosci. 22:2002;7453-7461
    • (2002) J. Neurosci. , vol.22 , pp. 7453-7461
    • Messaoudi, E.1    Ying, S.W.2    Kanhema, T.3    Croll, S.D.4    Bramham, C.R.5
  • 52
    • 0029807584 scopus 로고    scopus 로고
    • TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons
    • Minichiello L., Klein R. TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons. Genes Dev. 10:1996;2849-2858
    • (1996) Genes Dev. , vol.10 , pp. 2849-2858
    • Minichiello, L.1    Klein, R.2
  • 56
    • 0034666119 scopus 로고    scopus 로고
    • Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats
    • Mizuno M., Yamada K., Olariu A., Nawa H., Nabeshima T. Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats. J. Neurosci. 20:2000;7116-7121
    • (2000) J. Neurosci. , vol.20 , pp. 7116-7121
    • Mizuno, M.1    Yamada, K.2    Olariu, A.3    Nawa, H.4    Nabeshima, T.5
  • 58
    • 0030991457 scopus 로고    scopus 로고
    • Intact spatial learning and memory in transgenic mice with reduced BDNF
    • Montkowski A., Holsboer F. Intact spatial learning and memory in transgenic mice with reduced BDNF. NeuroReport. 8:1997;779-782
    • (1997) NeuroReport , vol.8 , pp. 779-782
    • Montkowski, A.1    Holsboer, F.2
  • 60
    • 0033600503 scopus 로고    scopus 로고
    • Deprivation of endogenous brain-derived neurotrophic factor results in impairment of spatial learning and memory in adult rats
    • Mu J.S., Li W.P., Yao Z.B., Zhou X.F. Deprivation of endogenous brain-derived neurotrophic factor results in impairment of spatial learning and memory in adult rats. Brain Res. 835:1999;259-265
    • (1999) Brain Res. , vol.835 , pp. 259-265
    • Mu, J.S.1    Li, W.P.2    Yao, Z.B.3    Zhou, X.F.4
  • 61
    • 0029031207 scopus 로고
    • BDNF protein measured by a novel enzyme immunoassay in normal brain and after seizure: Partial disagreement with mRNA levels
    • Nawa H., Carnahan J., Gall C. BDNF protein measured by a novel enzyme immunoassay in normal brain and after seizure: partial disagreement with mRNA levels. Eur. J. Neurosci. 7:1995;1527-1535
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 1527-1535
    • Nawa, H.1    Carnahan, J.2    Gall, C.3
  • 62
    • 0036724341 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: Evidence from a family-based association study
    • Neves-Pereira M., Mundo E., Muglia P., King N., Macciardi F., Kennedy J.L. The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study. Am. J. Hum. Genet. 71:2002;651-655
    • (2002) Am. J. Hum. Genet. , vol.71 , pp. 651-655
    • Neves-Pereira, M.1    Mundo, E.2    Muglia, P.3    King, N.4    MacCiardi, F.5    Kennedy, J.L.6
  • 63
  • 64
    • 0027075042 scopus 로고
    • Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs
    • Patterson S.L., Grover L.M., Schwartzkroin P.A., Bothwell M. Neurotrophin expression in rat hippocampal slices: a stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs. Neuron. 9:1992;1081-1088
    • (1992) Neuron , vol.9 , pp. 1081-1088
    • Patterson, S.L.1    Grover, L.M.2    Schwartzkroin, P.A.3    Bothwell, M.4
  • 65
    • 0030176079 scopus 로고    scopus 로고
    • Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice
    • Patterson S.L., Abel T., Deuel T.A., Martin K.C., Rose J.C., Kandel E.R. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron. 16:1996;1137-1145
    • (1996) Neuron , vol.16 , pp. 1137-1145
    • Patterson, S.L.1    Abel, T.2    Deuel, T.A.3    Martin, K.C.4    Rose, J.C.5    Kandel, E.R.6
  • 66
    • 0036318503 scopus 로고    scopus 로고
    • Role of heparin-binding growth-associated molecule (HB-GAM) in hippocampal LTP and spatial learning revealed by studies on overexpressing and knockout mice
    • Pavlov I., Voikar V., Kaksonen M., Lauri S.E., Hienola A., Taira T., Rauvala H. Role of heparin-binding growth-associated molecule (HB-GAM) in hippocampal LTP and spatial learning revealed by studies on overexpressing and knockout mice. Mol. Cell. Neurosci. 20:2002;330-342
    • (2002) Mol. Cell. Neurosci. , vol.20 , pp. 330-342
    • Pavlov, I.1    Voikar, V.2    Kaksonen, M.3    Lauri, S.E.4    Hienola, A.5    Taira, T.6    Rauvala, H.7
  • 67
    • 0035234670 scopus 로고    scopus 로고
    • Neurotrophins as synaptic modulators
    • Poo M.M. Neurotrophins as synaptic modulators. Nat. Rev. Neurosci. 2:2001;24-32
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 24-32
    • Poo, M.M.1
  • 68
    • 0033564051 scopus 로고    scopus 로고
    • Impairments in high-frequency transmission, synaptic vesicle docking, and synaptic protein distribution in the hippocampus of BDNF knockout mice
    • Pozzo-Miller L.D., Gottschalk W., Zhang L., McDermott K., Du J., Gopalakrishnan R., Oho C., Sheng Z.-H., Lu B. Impairments in high-frequency transmission, synaptic vesicle docking, and synaptic protein distribution in the hippocampus of BDNF knockout mice. J. Neurosci. 19:1999;4972-4983
    • (1999) J. Neurosci. , vol.19 , pp. 4972-4983
    • Pozzo-Miller, L.D.1    Gottschalk, W.2    Zhang, L.3    McDermott, K.4    Du, J.5    Gopalakrishnan, R.6    Oho, C.7    Sheng, Z.-H.8    Lu, B.9
  • 69
    • 0034792085 scopus 로고    scopus 로고
    • Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity
    • Rios M., Fan G., Fekete C., Kelly J., Bates B., Kuehn R., Lechan R.M., Jaenisch R. Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Mol. Endocrinol. 15:2001;1748-1757
    • (2001) Mol. Endocrinol. , vol.15 , pp. 1748-1757
    • Rios, M.1    Fan, G.2    Fekete, C.3    Kelly, J.4    Bates, B.5    Kuehn, R.6    Lechan, R.M.7    Jaenisch, R.8
  • 70
    • 0037563890 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor, behavior, and new directions for the treatment of mental disorders
    • Russo-Neustadt A. Brain-derived neurotrophic factor, behavior, and new directions for the treatment of mental disorders. Semin. Clin. Neuropsychiatry. 8:2003;109-118
    • (2003) Semin. Clin. Neuropsychiatry , vol.8 , pp. 109-118
    • Russo-Neustadt, A.1
  • 72
    • 0033847296 scopus 로고    scopus 로고
    • Transgenic mice overexpressing truncated trkB neurotrophin receptors in neurons have impaired long-term spatial memory but normal hippocampal LTP
    • Saarelainen T., Pussinen R., Koponen E., Alhonen L., Wong G., Sirvio J., Castren E. Transgenic mice overexpressing truncated trkB neurotrophin receptors in neurons have impaired long-term spatial memory but normal hippocampal LTP. Synapse. 38:2000;102-104
    • (2000) Synapse , vol.38 , pp. 102-104
    • Saarelainen, T.1    Pussinen, R.2    Koponen, E.3    Alhonen, L.4    Wong, G.5    Sirvio, J.6    Castren, E.7
  • 73
    • 0035665397 scopus 로고    scopus 로고
    • TrkB-receptor activation contributes to the kainate-induced increase in BDNF mRNA synthesis
    • Saarelainen T., Vaittinen S., Castren E. trkB-receptor activation contributes to the kainate-induced increase in BDNF mRNA synthesis. Cell. Mol. Neurobiol. 21:2001;429-435
    • (2001) Cell. Mol. Neurobiol. , vol.21 , pp. 429-435
    • Saarelainen, T.1    Vaittinen, S.2    Castren, E.3
  • 75
    • 0034536215 scopus 로고    scopus 로고
    • The neurotrophin hypothesis for synaptic plasticity
    • Schinder A.F., Poo M. The neurotrophin hypothesis for synaptic plasticity. Trends Neurosci. 23:2000;639-645
    • (2000) Trends Neurosci. , vol.23 , pp. 639-645
    • Schinder, A.F.1    Poo, M.2
  • 76
    • 2342537935 scopus 로고    scopus 로고
    • Selectivity in neurotrophin signaling: Theme and variations
    • Segal R.A. Selectivity in neurotrophin signaling: theme and variations. Annu. Rev. Neurosci. 18:2003;18
    • (2003) Annu. Rev. Neurosci. , vol.18 , pp. 18
    • Segal, R.A.1
  • 79
    • 0028238769 scopus 로고
    • Functions of the neurotrophins during nervous system development: What the knockouts are teaching us
    • Snider W.D. Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. Cell. 77:1994;627-638
    • (1994) Cell , vol.77 , pp. 627-638
    • Snider, W.D.1
  • 83
    • 0036742611 scopus 로고    scopus 로고
    • From acquisition to consolidation: On the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning
    • Tyler W.J., Alonso M., Bramham C.R., Pozzo-Miller L.D. From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. Learn. Mem. 9:2002;224-237
    • (2002) Learn. Mem. , vol.9 , pp. 224-237
    • Tyler, W.J.1    Alonso, M.2    Bramham, C.R.3    Pozzo-Miller, L.D.4
  • 85
    • 0036195750 scopus 로고    scopus 로고
    • Long-term monitoring of hippocampus-dependent behavior in naturalistic settings: Mutant mice lacking neurotrophin receptor TrkB in the forebrain show spatial learning but impaired behavioral flexibility
    • Vyssotski A.L., Dell'Omo G., Poletaeva I.I., Vyssotsk D.L., Minichiello L., Klein R., Wolfer D.P., Lipp H.P. Long-term monitoring of hippocampus-dependent behavior in naturalistic settings: mutant mice lacking neurotrophin receptor TrkB in the forebrain show spatial learning but impaired behavioral flexibility. Hippocampus. 12:2002;27-38
    • (2002) Hippocampus , vol.12 , pp. 27-38
    • Vyssotski, A.L.1    Dell'Omo, G.2    Poletaeva, I.I.3    Vyssotsk, D.L.4    Minichiello, L.5    Klein, R.6    Wolfer, D.P.7    Lipp, H.P.8
  • 86
    • 0034608881 scopus 로고    scopus 로고
    • Deficient long-term memory and long-lasting long-term potentiation in mice with a targeted deletion of neurotrophin-4 gene
    • Xie C.W., Sayah D., Chen Q.S., Wei W.Z., Smith D., Liu X. Deficient long-term memory and long-lasting long-term potentiation in mice with a targeted deletion of neurotrophin-4 gene. Proc. Natl. Acad. Sci. U. S. A. 97:2000;8116-8121
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 8116-8121
    • Xie, C.W.1    Sayah, D.2    Chen, Q.S.3    Wei, W.Z.4    Smith, D.5    Liu, X.6
  • 87
    • 0034666105 scopus 로고    scopus 로고
    • The role of brain-derived neurotrophic factor receptors in the mature hippocampus: Modulation of long-term potentiation through a presynaptic mechanism involving TrkB
    • Xu B., Gottschalk W., Chow A., Wilson R.I., Schnell E., Zang K., Wang D., Nicoll R.A., Lu B., Reichardt L.F. The role of brain-derived neurotrophic factor receptors in the mature hippocampus: modulation of long-term potentiation through a presynaptic mechanism involving TrkB. J. Neurosci. 20:2000;6888-6897
    • (2000) J. Neurosci. , vol.20 , pp. 6888-6897
    • Xu, B.1    Gottschalk, W.2    Chow, A.3    Wilson, R.I.4    Schnell, E.5    Zang, K.6    Wang, D.7    Nicoll, R.A.8    Lu, B.9    Reichardt, L.F.10
  • 88
    • 0033710349 scopus 로고    scopus 로고
    • Cortical degeneration in the absence of neurotrophin signaling: Dendritic retraction and neuronal loss after removal of the receptor TrkB
    • Xu B., Zang K., Ruff N.L., Zhang Y.A., McConnell S.K., Stryker M.P., Reichardt L.F. Cortical degeneration in the absence of neurotrophin signaling: dendritic retraction and neuronal loss after removal of the receptor TrkB. Neuron. 26:2000;233-245
    • (2000) Neuron , vol.26 , pp. 233-245
    • Xu, B.1    Zang, K.2    Ruff, N.L.3    Zhang, Y.A.4    McConnell, S.K.5    Stryker, M.P.6    Reichardt, L.F.7
  • 89
    • 0037016553 scopus 로고    scopus 로고
    • Role for brain-derived neurotrophic factor in learning and memory
    • Yamada K., Mizuno M., Nabeshima T. Role for brain-derived neurotrophic factor in learning and memory. Life Sci. 70:2002;735-744
    • (2002) Life Sci. , vol.70 , pp. 735-744
    • Yamada, K.1    Mizuno, M.2    Nabeshima, T.3
  • 90
    • 0036523102 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: Requirement for ERK activation coupled to CREB and upregulation of Arc synthesis
    • Ying S.W., Futter M., Rosenblum K., Webber M.J., Hunt S.P., Bliss T.V., Bramham C.R. Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: requirement for ERK activation coupled to CREB and upregulation of Arc synthesis. J. Neurosci. 22:2002;1532-1540
    • (2002) J. Neurosci. , vol.22 , pp. 1532-1540
    • Ying, S.W.1    Futter, M.2    Rosenblum, K.3    Webber, M.J.4    Hunt, S.P.5    Bliss, T.V.6    Bramham, C.R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.