A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response

Cell

Volumn 157, Issue 4, 2014, Pages 869-881

  Alpatov, Roman ^a,b   Lesch, Bluma J ^c   Nakamoto Kinoshita, Mika ^d   Blanco, Andres ^a,b   Chen, Shuzhen ^a,b   Stützer, Alexandra ^e   Armache, Karim J ^b   Simon, Matthew D ^b   Xu, Chao ^f   Ali, Muzaffar ^g   Murn, Jernej ^a,b   Prisic, Sladjana ^b   Kutateladze, Tatiana G ^g   Vakoc, Christopher R ^h   Min, Jinrong ^f   Kingston, Robert E ^b   Fischle, Wolfgang ^e   Warren, Stephen T ^d   Page, David C ^c   Shi, Yang ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^f UNIVERSITY OF TORONTO   (Canada)

^g UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^h Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FRAGILE X MENTAL RETARDATION PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; FRAGILE X SYNDROME; GAMETOGENESIS; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; INTELLECTUAL IMPAIRMENT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SPERMATOGENESIS; ADULT; CHROMATIN; DNA DAMAGE RESPONSE; FEMALE; HISTONE METHYLATION; IN VITRO STUDY; IN VIVO STUDY; MEIOSIS; MOLECULAR DYNAMICS; PHENOTYPE; PROTEIN PHOSPHORYLATION;

ANIMALS; CHROMATIN; CHROMOSOME PAIRING; DNA DAMAGE; EMBRYO, MAMMALIAN; FIBROBLASTS; FRAGILE X MENTAL RETARDATION PROTEIN; HIPPOCAMPUS; HISTONES; HUMANS; MALE; MEIOSIS; MICE; MICE, KNOCKOUT; MUTATION; NEURONS; PROPHASE; RECEPTORS, AMPA; SPERMATOGENESIS;

EID: 84900333592     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2014.03.040     Document Type: Article

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