Positive feedback regulation of Akt-FMRP pathway protects neurons from cell death

Journal of Neurochemistry

Volumn 123, Issue 2, 2012, Pages 226-238

  Jeon, Se Jin ^a,b   Han, Seol Heui ^b   Yang, Sung Il ^b   Choi, Ji Woong ^f   Kwon, Kyoung Ja ^b   Park, Seung Hwa ^b   Kim, Hahn Young ^b   Cheong, Jae Hoon ^c   Ryu, Jong Hoon ^d   Ko, Kwang Ho ^a   Wells, David G ^e   Shin, Chan Young ^b  

^a Seoul National University   (South Korea)

^b Konkuk University School of Medicine   (South Korea)

^c Sahmyook University   (South Korea)

^d Kyung Hee University   (South Korea)

^e YALE UNIVERSITY   (United States)

^f Gachon University College of Medicine   (South Korea)

Author keywords

Akt; Bcl xL; FMRP; glutamate; ischemia; neuronal survival

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; FRAGILE X MENTAL RETARDATION PROTEIN; PROTEIN BCL XL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; FMR1 GENE; FRAGILE X SYNDROME; GENE EXPRESSION REGULATION; GENE MUTATION; GENE OVEREXPRESSION; IN VITRO STUDY; IN VIVO STUDY; MALE; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RADIOIMMUNOPRECIPITATION; RAT; SIGNAL TRANSDUCTION; SYNAPSE; UPREGULATION;

ANIMALS; APOPTOSIS; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; FEEDBACK, PHYSIOLOGICAL; FRAGILE X MENTAL RETARDATION PROTEIN; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; NEURONS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

RATTUS;

EID: 84867067796     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07886.x     Document Type: Article

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