Interhomolog bias during meiotic recombination: Meiotic functions promote a highly differentiated interhomolog-only pathway

Cell

Volumn 90, Issue 6, 1997, Pages 1123-1135

  Schwacha, Anthony ^a,b   Kleckner, Nancy ^a  

^a HARVARD UNIVERSITY   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOME PROTEIN;

ARTICLE; CHROMATID; GENETIC RECOMBINATION; MEIOSIS; MITOSIS; NONHUMAN; PRIORITY JOURNAL; SISTER CHROMATID; YEAST;

EID: 0030886852     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80378-5     Document Type: Article

References (48)

1. Anderson, L.K., Offenberg, H.H., Verkuijlen, W.M.H.D., and Heyting, C. (1997). RecA-like proteins are components of early meiotic nodules in lily. Proc. Natl. Acad. Sci. USA 94, 6868-6873.
2. Bai, Y., and Symington, L.S. (1996). A Rad52 homolog is required for RAD51-independent mitotic recombination in Saccharomyces cerevisaie. Genes Dev. 10, 2025-2037.
3. Baudat, F., and Nicolas, A. (1997). Clustering of meiotic double-strand breaks on yeast chromosome III. Proc. Natl. Acad. Sci. USA 94, 5213-5218.
4. Baumann, P., Benson, F.E., and West, S.C. (1996). Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro. Cell 87, 757-766.
5. Bishop, D.K. (1994). RecA homologs Dmc1 and Rad51 interact to form multiple nuclear complexes prior to meiotic chromosome synapsis. Cell 79, 1081-1092.
6. Bishop, D.K., Park, D., Xu, L, and Kleckner, N. (1992). DMC1: a meiosis-specific yeast homolog of bacterial recA required for meiotic recombination, synaptonemal complex formation and cell cycle progression. Cell 69, 439-456.
7. Borts, R.H., Lichten, M., and Haber, J.E. (1986). Analysis of meiosis-defective mutations in yeast by physical monitoring of recombination. Genetics 113, 551-567.
8. Bullard, S.A., Kim, S., Galbraith, A.M., and Malone, R.E. (1996). Double strand breaks at the HIS2 recombination hot spot in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 93, 13054-13059.
9. Cao, L., Alani, E., and Kleckner, N. (1990). A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae. Cell 61, 1089-1101.
10. Collins, I., and Newlon, C.S. (1994). Meiosis-specific formation of joint molecules containing sequences from homologous chromosomes. Cell 76, 65-75.
11. Fabre, F., Boulet, A., and Roman, H. (1984). Gene conversion at different points in the mitotic cycle of Saccharomyces cerevisiae. Mol. Gen. Genet. 195, 139-143.
12. Game, J.C., Sitney, K.C., Cook, V.E., and Mortimer, R.K. (1989). Use of a ring chromosome and pulsed-field gels for study of interhomolog recombination, double strand DNA breaks and sister-chromatid exchange in yeast. Genetics 123, 695-713.
13. Gilbertson, L., and Stahl, F.W. (1996). A test of the double strand break repair model for meiotic recombination in Saccharomyces cerevisiae. Genetics 144, 27-41.
14. Haber, J.E. (1997). A super new twist on the initiation of meiotic recombination. Cell 89, 163-166.
15. Haber, J.E., Thorburn, P.C., and Rogers, D. (1984). Meiotic and mitotic behavior of dicentric chromosomes in Saccharomyces cerevisiae. Genetics 706, 185-205.
16. Heyer, W.-D. (1994). The search for the right partner: homologous pairing and DNA strand exchange proteins in eukaryotes. Experientia 50, 223-233.
17. Ivanov, E.L., Sugawara, N., Fishman-Lobell, J., and Haber, J.E. (1996). Genetic requirements for the single-strand annealing pathway of double-strand break repair in Saccharomyces cerevisiae. Genetics 142, 693-704.
18. Jackson, J., and Fink, G.R. (1985). Meiotic recombination between duplicated genetic elements in Saccharomyces cerevisiae. Genetics 109, 303-332.
19. Jacq, C., Alt-Mörbe, J., Andre, B., Arnold, W., Bahr, A., Ballesta, J.P.G., Bargues, M., et al. (1997). The nucleotide sequence of Saccharomyces cerevisiae Chromosome IV. Nature 387(Suppl.) 75-78.
20. Kadyk, L.C., and Hartwell, L.H. (1992). Sister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiae. Genetics 132, 387-402.
21. Keeney, S., and Kleckner, N. (1996). Communication between homologous chromosomes: genetic alterations at a nuclease-hypersensitive site can alter mitotic chromatin structure at that site both in cis and in trans. Genes to Cells 1, 475-489.
22. Kleckner, N. (1996). Meiosis: how could it work? Proc. Natl. Acad. Sci. USA 93, 8167-8174.
23. Lin, F.L., Sperle, K., and Sternberg, N. (1984). Model for homologous recombination during transfer of DNA into mouse L cells: role for DNA ends in the recombination process. Mol. Cell. Biol. 4, 1020-1034.
24. Lydall, D., Nikolsky, Y., Bishop, D.K., and Weinert, T. (1996). A meiotic recombination checkpoint controlled by mitotic checkpoint genes. Nature 383, 840-843.
25. Mao-Draayer, Y., Galbraith, A.M., Pittman, D.L., Cool, M., and Malone, R.E. (1996). Analysis of meiotic recombination pathways in the yeast Saccharomyces cerevisiae. Genetics 144, 71-86.
26. Nassif, N., Penney, J., Pal, S., Engels, W.R., and Gloor, G.B. (1994). Efficient copying of nonhomologous sequences from ectopic sites via P-element-induced gap repair. Mol. Cell. Biol. 14, 1613-1625.
27. Padmore, R., Cao, L., and Kleckner. N. (1991). Temporal comparison of recombination and synaptonemal complex formation during meiosis in S. cerevisiae. Cell 66, 1239-1256.
28. Petes, T.D., and Pukkila, P.J. (1995). Meiotic sister chromatid recombination. Adv. Genet. 33, 41-62.
29. Porter, S.E., White, M.A., and Petes, T.D. (1993). Genetic evidence that meiotic recombination hot spot HIS4 locus of Saccharomyces cerevisiae does not represent a site for a symmetrically processed double strand break. Genetics 134, 5-19.
30. Rocco, V., and Nicolas, A. (1996). Sensing of DNA nonhomology lowers the initiation of meiotic recombination in yeast. Genes to Cells 1, 645-661.
31. Rockmill, B., and Boeder, G.S. (1988). RED1: a yeast gene required for the segregation of chromosomes during reductional division of meiosis. Proc. Natl. Acad. Sci. USA 85, 6057-6061.
32. Rockmill, B., and Roeder, G.S. (1990). Meiosis in asynaptic yeast. Genetics 126, 563-574.
33. Rockmill, B., Sym, M., Scherthan, H., and Roeder, G.S. (1995). Roles for two recA homologs in promoting meiotic chromosome synapsis. Genes Dev. 9, 2684-2695.
34. Schwacha, A. (1996). Isolation and characterization of branched meiotic recombination intermediates from both wild-type and mutant strains of the yeast Saccharomyces cerevisiae. PhD thesis, Harvard University, Cambridge, Massachusetts.
35. Schwacha, A., and Kleckner, N. (1994). Identification of joint molecules that form frequently between homologs but rarely between sister chromatids during yeast meiosis. Cell 76, 51-63.
36. Schwacha, A., and Kleckner, N. (1995). Identification of double Holliday junctions as intermediates in meiotic recombination. Cell 83, 783-791.
37. Sharp, P.M., and Lloyd, AT. (1993). Regional base composition variation along yeast chromosome III: evolution of chromosome primary structure. Nucleic Acids Res. 21, 179-183.
38. Shinohara, A., Ogawa, H., and Ogawa, T. (1992). Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein. Cell 69, 457-470.
39. Smith, A.V., and Roeder, G.S. (1997). The yeast Red1 protein localizes to the cores of meiotic chromosomes. J. Cell Biol. 136, 957-967.
40. Storlazzi, A., Xu, L., Cao, L., and Kleckner, N. (1995). Crossover and noncrossover recombination during meiosis: timing and pathway relationships. Proc. Natl. Acad. Sci. USA 92, 8512-8516.
41. Storlazzi, A., Xu, L., Schwacha, A., and Kleckner, N. (1996). Synaptonemal complex component Zip1 plays a role in meiotic recombination independent of SC polymerization along the chromosomes. Proc. Natl. Acad. Sci. USA 93, 9043-9048.
42. Sun, H., Dawson, D., and Szostak. J.W. (1991). Genetic and physical analyses of sister chromatid exchange in yeast meiosis. Mol. Cell. Biol. 11, 6328-6336.
43. Sung, P. (1994). Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast Rad51 protein. Science 265, 1241-1243.
44. Sung, P. (1997). Yeast rad55 and rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by rad51 recombinase. Genes Dev. 11, 1111-1121.
45. Weiner, B.M., and Kleckner, N. (1994). Chromosome pairing via multiple interstitial interactions before and during meiosis in yeast. Cell 77, 977-991.
46. Xu., L., and Kleckner, N. (1995). Sequence nonspecific double strand breaks and interhomolog interactions prior to double strand break formation at a meiotic recombination hot spot in yeast. EMBO J. 14, 5115-5128.
47. Xu, L., Weiner, B.M., and Kleckner, N. (1997). Meiotic cells monitor the status of the interhomolog recombination complex. Genes Dev. 11, 106-118.
48. Zenvirth, D., Loidl, J., Klein, S., Arbel, A., Shemesh, R., and Simchen, G. (1997). Switching yeast from meiosis to mitosis: double-strand break repair, recombination and synaptonemal complex. Genes to Cells, in press.