Evaluation and structure-activity relationship analysis of a new series of arylnaphthalene lignans as potential anti-tumor agents

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Luo, Jiaoyang ^a   Hu, Yichen ^a   Kong, Weijun ^a   Yang, Meihua ^a  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

Author keywords

[No Author keywords available]

Indexed keywords

6' HYDROXYJUSTICIDIN A; 6' HYDROXYJUSTICIDIN B; ANTINEOPLASTIC AGENT; ARYLNAPHTHALENE LIGNAN DERIVATIVE; CASPASE 3; CHINENSINAPHTHOL METHYL ETHER; ETOPOSIDE; JUSTICIDIN B; LIGNAN DERIVATIVE; PACLITAXEL; PODOPHYLLOTOXIN; SUPEROXIDE DISMUTASE; TAIWANIN E METHYL ETHER; UNCLASSIFIED DRUG; 1,3 DIOXOLANE DERIVATIVE; JUSTICIDIN A; LIGNAN; NAPHTHALENE DERIVATIVE;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVITY; GROWTH INHIBITION; HUMAN; HUMAN CELL; JUSTICIA (PLANT); JUSTICIA PROCUMBENS; LEUKEMIA CELL LINE; STRUCTURE ACTIVITY RELATION; ACANTHACEAE; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; ISOLATION AND PURIFICATION; K562 CELL LINE; METABOLISM; SIGNAL TRANSDUCTION;

ACANTHACEAE; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; CELL PROLIFERATION; CELL SURVIVAL; DIOXOLANES; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; K562 CELLS; LIGNANS; NAPHTHALENES; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; SUPEROXIDE DISMUTASE;

EID: 84899870087     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093516     Document Type: Article

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