Application of a sensitive and specific LC-MS/MS method for determination of chinensinaphthol methyl ether in rat plasma for a bioavailability study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 903, Issue , 2012, Pages 75-80

  Zhou, Shujun ^a,b   Qiu, Feng ^a   Tong, Zhanqi ^c   Yang, Shihai ^b   Yang, Meihua ^a  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b JILIN AGRICULTURAL UNIVERSITY   (China)

^c CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Bioavailability; Chinensinaphthol methyl ether; Justicia procumbens; LC MS MS; Rat

Indexed keywords

ACANTHACEAE; ACTIVE INGREDIENTS; AGILENT; ANALYTES; BIOAVAILABILITY; BIOAVAILABILITY STUDY; ETHYL ACETATES; IN-VIVO; INTERNAL STANDARDS; INTRA-DAY ACCURACY; JUSTICIA PROCUMBENS; LC-MS/MS; LOWER LIMIT OF QUANTIFICATIONS; METHYL ETHERS; MOBILE PHASE; ORAL ADMINISTRATION; PHARMACOKINETIC EVALUATION; POSITIVE ELECTROSPRAY IONIZATION; POSITIVE ION MODE; RAT PLASMA; TANDEM-MASS SPECTROMETRY;

ACETONITRILE; BODY FLUIDS; ELECTROSPRAY IONIZATION; ETHERS; FORMIC ACID; MASS SPECTROMETRY; RATS;

BIOCHEMISTRY;

ACETONITRILE; BUSPIRONE; CHINENSINAPHTHOL METHYL ETHER; ETHER DERIVATIVE; PLANT EXTRACT; UNCLASSIFIED DRUG; WATER;

ANIMAL EXPERIMENT; ARTICLE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; ELECTROSPRAY; ELUTION; IN VIVO STUDY; JUSTICIA (PLANT); JUSTICIA PROCUMBENS; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

ACANTHACEAE; ANIMALS; BUSPIRONE; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; LEAST-SQUARES ANALYSIS; MALE; NAPHTHOLS; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

ACANTHACEAE; JUSTICIA PROCUMBENS; RATTUS;

EID: 84864927798     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.06.045     Document Type: Article

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