Modulation of intercellular ROS signaling of human tumor cells

Anticancer Research

Volumn 29, Issue 11, 2009, Pages 4559-4570

  Bechtel, Wibke ^a,b   Bauer, Georg ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Catalase; HOCl signaling pathway; Hydrogen peroxide; Hydroxyl radical; Hypochlorous acid

Indexed keywords

AMITROLE; CATALASE; CHLORO [[2,2' [1,2 ETHANEDIYLBIS [(NITRILO KAPPAN)METHYLIDYNE]]BIS[6 METHOXYPHENOLATO KAPPAO]]]MANGANESE; FERROUS ION; HYDROGEN PEROXIDE; HYDROXYL RADICAL; MANGANESE DERIVATIVE; MYELOPEROXIDASE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME INHIBITION; FENTON REACTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR CELL;

AMITROLE; APOPTOSIS; CATALASE; CELL LINE, TUMOR; ENZYME INHIBITORS; HUMANS; HYDROGEN PEROXIDE; HYPOCHLOROUS ACID; NADPH OXIDASE; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS;

EID: 75149138984     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Irani K, Xia Y, Zweier JL, Sollott SJ, Der CJ, Fearon ER, Sundaresan M, Finkel T and Goldschmidt-Clermont PJ: Mitogenic signalling by oxidants in Ras-transformed fibroblasts. Science 275: 1649-1652, 1997.
2. Suh Y-A, Arnold RS, Lassegue B, Shi J, Xu X, Sorescu D, Chung AB, Griendling KK and Lambeth JD: Cell transformation by the superoxide-generating oxidase MOX1. Nature 401: 79-82, 1999.
3. Yang JQ, Li S, Domann FE, Buettner G and Oberley LW: Superoxide generation in v-Ha-ras-transduced human keratinocyte HaCaT cells. Mol Carcinogenesis 26: 180-188, 1999.
4. Arnold RS, Shi J, Murad E, Whalen AM, Sun CQ, Palavarapu R, Parthasarathy S, Petros JA and Lambeth JD: Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase NOX1. Proc Natl Acad Sci USA 98: 5550-5555, 2001.
5. Mitsushita J, Lambeth JD and Kamata T: The superoxide-generating oxidase NOX1 is functionally required for Ras oncogenic transformation. Cancer Res 64: 3580-3585, 2004.
6. Jürgensmeier J, Schmitt CP, Viesel E, Höfler P and Bauer G: TGF-β-treated normal fibroblasts eliminate transformed fibroblasts by induction of apoptosis. Cancer Res 54: 393-398, 1994.
7. Herdener M, Heigold S, Saran M and Bauer G: Target cell-derived superoxide anions cause efficiency and selectivity of intercellular induction of apoptosis. Free Radical Biol Med 29: 1260-1271, 2000.
8. Schwieger A, Bauer L, Hanusch J, Sers C, Schäfer R and Bauer G: Ras oncogene expression determines sensitivity for intercellular induction of apoptosis. Carcinogenesis 22: 1385-1392, 2001.
9. Bauer G: Elimination of transformed cells by normal cells: a novel concept for the control of carcinogenesis. Histol Histopathol 11: 237-255, 1996.
10. Bauer G: Reactive oxygen and nitrogen species: efficient, selective and interactive signals during intercellular induction of apoptosis. Anticancer Res 20: 4115-4140, 2000.
11. Bauer G: Signaling and proapoptotic functions of transformed cell-derived reactive oxygen species. Prostaglandines, Leukot Essent Fatty Acids 66: 41-56, 2002.
12. Bechtel W and Bauer G: Catalase protects tumor cells from apoptosis by intercellular ROS signalling. Anticancer Res 29: 4541-4558, 2009.
13. Engelmann I and Bauer G: How can tumor cells escape intercellular induction of apoptosis? Anticancer Res 20: 2297-2306, 2000.
14. Engelmann I, Eichholtz-Wirth H and Bauer G: Ex vivo tumor cell lines are resistant against intercellular induction of apoptosis and independent of exogenous survival factors. Anticancer Res 20: 2361-2370, 2000.
15. Bauer G: Low-dose radiation and intercellular induction of apoptosis: potential implications for the control of oncogenesis. Int J Radiation Biol 83: 887-902, 2007.
16. Diatchuk V, Lotan O, Koshkin V, Wikstroem P and Pick E: Inhibition of NADPH oxidase activation by 4-(2-aminoethyl-) benzenesulfonyl fluoride and related compounds. J Biol Chem 272: 13292-13301, 1997.
17. Kettle AJ, Gedye CA, Hampton MB, and Winterbourn CC: Inhibition of myeloperoxidase by benzoic acid hydrazides. Biochem J 308: 559-563, 1995.
18. Kettle AJ, Gedye CA and Winterbourn CC: Mechanisms of inactivation of myeloperoxidase by 4-aminobenzoic acid hydrazide. Biochem J 321: 503-508, 1997.
19. Putnam CD, Arvai AS and Bourne Y: Active and inhibited human catalase structures: Ligand and NADPH binding and catalytic mechanism. J Mol Biol 296: 295-309, 2000.
20. Goldstein S and Czapski G: Mannitol as an OH. scavenger in aqueous solutions and in biological systems. Int J Rad Biol 46: 725-729, 1984.
21. Aruoma OI, Halliwell B, Hoey BM and Butler J: The antioxidant action of taurine, hypotaurine and their metabolic precursors. Biochem J 256: 251-256, 1988.
22. Klebanoff SJ: Myeloperoxidase: friend and foe. J Leucocyte Biol 77: 1-28, 2005.
23. Konorev EA, Kennedy MC and Kalyanaraman B: Cell-permeable superoxide dismutase and glutathione peroxidase mimetics afford superior protection against doxorubicin-induced cardiotoxicity: The role of reactive oxygen and nitrogen intermediates. Arch Biochem Biophys 368: 421-428, 1999.
24. Estevez AG, Sampson JB, Zhuang YX, Spear N, Richardson GJ, Crow JP, Tarpey MM, Barbeito L and Beckman JS: Liposome-delivered superoxide dismutase prevents nitric oxide-dependent motor neuron death induced by trophic factor withdrawal. Free Radical Biol Med 28: 437-446, 2000.
25. Heigold S, Sers C, Bechtel W, Ivanovas B, Schäfer R and Bauer G: Nitric oxide mediates apoptosis induction selectively in transformed fibroblasts compared to nontransformed fibroblasts. Carcinogenesis 23: 929-941, 2002.
26. Bracht K, Kiefer T, Dölken G and Bednarski PJ: Characterization of three B-cell lymphoma cell lines from chemotherapy resistant patients with respect to in vitro sensitivity to 21 antitumor agents, ABC-transporter expression and cellular redox status. Cancer Res Clin Oncol 133: 957-967, 2007.
27. Ivanovas B and Bauer G: Selective and nonselective apoptosis induction in transformed and nontransformed fibroblasts by exogenous reactive oxygen and nitrogen species. Anticancer Res 22: 841-856, 2002.
28. Bauer G, Dormann S, Engelmann I, Schulz A and Saran M: Reactive oxygen species and apoptosis. In: Handbook of Experimental Pharmacology. Cameron RG and Feuer G (ed.). Berlin, Springer Verlag, vol. 142, pp. 275-318, 2000.
29. Haberstroh K, Heigold S and Bauer G: Transformed cell-derived reactive oxygen species support and inhibit nitric oxide-mediated apoptosis induction. Int J Oncol 21: 145-151, 2002.
30. Folkes LK, Candeias LP and Wardman P: Kinetics and mechanisms of hypochlorous acid reactions. Arch Biochem Biophys 323: 120-126, 1995.
31. Connick RE: The interaction of hydrogen peroxide and hypochlorous acid in acidic solutions containing chloride ion. J Am Chem Soc 69: 1509-1514, 1947.
32. Held AM, Halko DJ and Hurst JK: Mechanisms of chlorine oxidation of hydrogen peroxide. J Am Chem Soc 100: 5732-5740, 1978.
33. Klotz L-O, Kröncke K-D and Sies H: Singlet oxygen-induced signaling effects in mammalian cells. Photochem Photobiol Sci 2: 88-94, 2003.
34. Long CA and Bielski BH: Rate of reaction of superoxide radical with chloride-containing species. J Phys Chem 84: 555-557, 1980.
35. Candeias LP, Patel KB, Stratford MRL and Wardmann P: Free hydroxyl radicals are formed on reaction between the neutrophil-derived species superoxide anion and hypochlorous acid. FEBS 333: 151-153, 1993.
36. Halliwell B and Gutteridge JMC: Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem J 219: 1-14, 1984.