LC-ESI-MS/MS analysis and pharmacokinetics of 6'-hydroxy justicidin A, a potential antitumor active component isolated from Justicia procumbens, in rats

Journal of Pharmaceutical and Biomedical Analysis

Volumn 70, Issue , 2012, Pages 539-543

  Qiu, Feng ^a   Zhou, Shujun ^a,b   Fu, Shujun ^c   Kong, Weijun ^a   Yang, Shihai ^b   Yang, Meihua ^a  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b JILIN AGRICULTURAL UNIVERSITY   (China)

^c International Joint Academy of Biotechnology and Medicine   (China)

Author keywords

6' Hydroxy justicidin A; Justicia procumbens; LC ESI MS MS; Pharmacokinetics; Rat

Indexed keywords

6 HYDROXY JUSTICIDIN A; ACETONITRILE; ANTINEOPLASTIC AGENT; BUSPIRONE; FORMIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; ELECTROSPRAY MASS SPECTROMETRY; JUSTICIA (PLANT); JUSTICIA PROCUMBENS; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ACANTHACEAE; ACETONITRILES; ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CALIBRATION; CHROMATOGRAPHY, LIQUID; FORMATES; HALF-LIFE; INJECTIONS, INTRAVENOUS; LIGNANS; LIMIT OF DETECTION; LIQUID-LIQUID EXTRACTION; MALE; METABOLIC CLEARANCE RATE; PLANTS, MEDICINAL; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84866247911     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.05.002     Document Type: Article

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