In vitro antileishmanial activity of diphyllin isolated from Haplophyllum bucharicum

Planta Medica

Volumn 71, Issue 4, 2005, Pages 366-369

  Di Giorgio, Carole ^a   Delmas, Florence ^a   Akhmedjanova, Valentina ^b   Ollivier, Evelyne ^a   Bessonova, Iraida ^b   Riad, Elias ^a   Timon David, Pierre ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b S Yu Yunusov Institute of the Chemistry of Plant Substances Uzbekistan Academy of Sciences   (Uzbekistan)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOPURINOL; AMPHOTERICIN B; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; DIPROPHYLLINE; KETOCONAZOLE; PENTAMIDINE;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CELL CYCLE S PHASE; CYTOTOXICITY; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; HAPLOPHYLLUM BUCHARICHUM; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; INTERNALIZATION; LEISHMANIA; MACROMOLECULE; MACROPHAGE; NONHUMAN; PHAGOCYTOSIS; PLANT; PROMASTIGOTE; PROTEIN SYNTHESIS; UZBEKISTAN;

ANIMALS; ANTIPROTOZOAL AGENTS; CELL CYCLE; DIOXOLANES; LEISHMANIA; LEISHMANIASIS; LIGNANS; MACROPHAGES; PARASITIC SENSITIVITY TESTS; PHYTOTHERAPY; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; RUTACEAE;

HAPLOPHYLLUM; RUTACEAE;

EID: 18744407303     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-864106     Document Type: Article

References (20)

1. WHO. Fact sheet N°116. www.who.int/health-topics/leishmaniasis.htm
2. AH A. Leishmaniases and HIV/AIDS co-infections: review of common features and management experiences. Ethiop Med J 2002; 21: 37-49
3. Sindermann H, Croft SL, Engel KR, Bommer W, Eibl HJ, Linger C, Engel J. Miltefosine (Impavido): the first oral treatment against leishmaniasis. Med Microbiol Immunol (Berl), 2003: Sept 26
4. Croft SL, Coombs GH. Leishmaniasis - current chemotherapy and recent advances in the search for novel drugs. Trends Parasitol 2003; 19: 502-8
5. Berman J. Current treatment approaches to leishmaniasis. Curr Opin Infect Dis 2003; 5: 397-401
6. Day SH, Lin YC, Tsai ML, Tsao LT, Ko HH, Chung MI, Lee JC, Wang JP, Won SJ, Lin CN. Potent cytotoxic lignans from justicia procumbens and their effects on nitric oxide and tumor necrosis factor-alpha production in mouse macrophages. J Nat Prod 2002; 65: 379-81
7. Fukamiya N, Lee KH. Antitumor agents, 81. Justicidin-A and diphyllin, two cytotoxic principles from Justicia procumbens. J Nat Prod 1986; 49: 348-50
8. Asano J, Chiba K, Tada M, Yoshii T. Antiviral activity of lignans and their glycosides from Justicia procumbens. Phytochemistry 1996; 42: 713-7
9. Pradheepkumar CP, Shanmugam G. Anticancer potential of cleistanthin A isolated from the tropical plant Cleistanthus collinus. Oncol Res 1999; 11: 225-32
10. Sibley DL, Norma A. Cell invasion by un-palatable parasites. Traffic 2000; 1: 100-6
11. Nesmelova EF, Razakova DM, Akhmedjanova VI, Bessonova IA. Diphyllin from Haplophyllum alberti-regelii, H. bucharicum, and H. perforatum. Chemistry of Natural Compounds 1983; 19: 608-9
12. Al-Abed Y, Abu-Zarga M, Sabri S, Atta-Ur-Rahman, Voelter W. An arylnaphthalene Iignan from Haplophyllum buxbaumii, Phytochemistry 1998; 49: 1779-81
13. Al-Rehaily AJ, Al-Howiriny TA, Ahmad MS, Al-Yahya MA, El-Feraly FS, Hufford CD, McPhail AT. Alkaloids from Haplophyllum tuberculatum. Phytochemistry 2001; 57: 597-602
14. Di Giorgio C, Delmas F, Robin M, Seferian L, Azas N, Gasquet M, Costa M, Timon-David P, Galy JP. In vitro antileishmanial activity of 7-substituted 9-chloro and 9-amino-2-methoxyacridines and their bis- and tetra-acridine complexes towards parasites of the species Leishmania infantum. Antimicrobial Agents and Chemotherapy 2003; 47: 174-80
15. Ogunkolade BW, Colomb-Valet I, Monjour L, Rhodes-Feuillette A, Abita JP, Frommel D. Interactions between the human monocytic leukaemia THP1 cell line and Old and New World species of Leishmania. Acta Tropica 1990; 47: 171-6
16. Crissman HA, Darzynkiewicz Z, Steinkamp JA, Tobey RA. Simultaneous fluorescent labelling of DNA, RNA, and protein. Methods Cell Biol 1990; 33: 305-14
17. Azas N, Di Giorgio C, Delmas F, Gasquet M, Timon-David P. Leishmania infantum promastigotes: flow cytometry as a possible tool for assessing the effects of drugs on cellular functions. Exp Parasitol 1997; 87: 1-7
18. Shapiro HM. Microbial analysis at the single-cell level: tasks and techniques. J Microbiol Methods 2000; 42: 3-16
19. Greenspan P, Mayer EP, Fowler SD. Nile red: a selective fluorescent stain for intracellularlipid droplets. J Cell Biol 1985; 100: 965-73
20. Ding AH, Nathan CF, Stuehr DJ. Release of reactive nitrogen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J Immunol 1988; 141: 2407-12