Quinazolines revisited: Search for novel anxiolytic and GABAergic agents

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 8, 2005, Pages 2145-2148

  Goel, R K ^a   Kumar, Vipan ^a   Mahajan, M P ^a  

^a GURU NANAK DEV UNIVERSITY   (India)

Author keywords

Anxiolytic; GABAergic; Microwave; Quinazolines

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; ANXIOLYTIC AGENT; DIAZEPAM; QUINAZOLINE DERIVATIVE;

ANIMAL EXPERIMENT; ANXIETY DISORDER; ARTICLE; COMPUTER AIDED DESIGN; CONTROLLED STUDY; CONVULSION; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG SCREENING; DRUG SYNTHESIS; MOUSE; NONHUMAN; TRANQUILIZING ACTIVITY;

EID: 15944377918     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.02.023     Document Type: Article

References (19)

1. W. Sieghart Trends Pharmacol. Sci. 13 1992 446
2. E. Sigel, and E.A. Barnard J. Biol. Chem. 259 1984 7219
3. F.A. Stephenson Biochem. J. 310 1995 1
4. B. Frølund, B. Ebert, U. Kristiansen, T. Liljefors, and P.K. Larsen Curr. Top. Med. Chem. 2 2002 817
5. S.Y. Tsang, and H. Xue Curr. Pharm. Des. 10 2004 1035
6. G.A. Johnston Pharmacol. Ther. 69 1996 173
7. W.E. Haefely Eur. Arch. Psychiatry Neurol. Sci. 238 1989 294
8. R.W. Olsen J. Neurochem. 37 1981 1
9. W. Sieghart Pharmacol. Rev. 47 1995 181
10. A/Benzodiazepine Receptor as Target for Psychoactive Drugs 1996 Springer Heidelberg, Germany
11. L.H. Sternbach J. Med. Chem. 22 1979 1
12. www.ibmh.msk.su
13. V. Poroikov, D. Filimonov, Yu. Borodina, A. Lagunin, and A. Kos J. Chem. Inf. Comput. Sci. 40 2000 1349
14. McNeil Lab.; GB 1573532; 1976; DE 2711757; Chem. Abstr.; EN; 88; 37603
15. V. Kumar, C. Mohan, M. Gupta, and M.P. Mahajan Tetrahedron 61 2005 3533
16. V. Kumar, A.K. Sharma, and M.P. Mahajan Synth. Commun. 34 2004 49
17. +)
18. C. Fernandes, and S.E. File Pharmacol. Biochem. Behav. 54 1996 31
19. Y. Kenji, W. Youko, A. Yutaka, and O. Akihiro Biol. Pharm. Bull. 24 2001 1068