Thermal adaptation of dihydrofolate reductase from the moderate thermophile geobacillus stearothermophilus

Biochemistry

Volumn 53, Issue 17, 2014, Pages 2855-2863

  Guo, Jiannan ^a   Luk, Louis Y P ^a   Loveridge, E Joel ^a   Allemann, Rudolf K ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; STABILITY;

DIHYDROFOLATE REDUCTASE; GEOBACILLUS STEAROTHERMOPHILUS; HIGH TEMPERATURE; HIGH THERMAL STABILITY; PROLINE RESIDUES; SITE DIRECTED MUTAGENESIS; STEAROTHERMOPHILUS; THERMAL ADAPTATION;

ENZYME ACTIVITY;

DIHYDROFOLATE REDUCTASE; GLUTAMINE; GLYCEROL; LIGAND; METHIONINE; PROLINE; SODIUM CHLORIDE; SUCROSE; WATER;

ANIMAL CELL; ARTICLE; BACTERIAL CELL; BACTERIAL STRAIN; CONTROLLED STUDY; GEOBACILLUS STEAROTHERMOPHILUS; HABITAT; HIGH TEMPERATURE; HYDROLYSIS; LIGAND BINDING; MELTING POINT; MORITELLA; MORITELLA PROFUNDA; NONHUMAN; OXIDATION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; TEMPERATURE ACCLIMATIZATION; THERMOPHILE; THERMOSTABILITY;

ADAPTATION, PHYSIOLOGICAL; AMINO ACID SEQUENCE; CIRCULAR DICHROISM; ENZYME STABILITY; GEOBACILLUS STEAROTHERMOPHILUS; HOT TEMPERATURE; KINETICS; MUTAGENESIS, SITE-DIRECTED; OSMOLAR CONCENTRATION; PROTEIN DENATURATION; PROTEIN STRUCTURE, SECONDARY; SOLVENTS; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 84899803746     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi500238q     Document Type: Article

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