The R35 residue of the influenza A virus NS1 protein has minimal effects on nuclear localization but alters virus replication through disrupting protein dimerization

Virology

Volumn 458-459, Issue 1, 2014, Pages 33-42

  Lalime, Erin N ^a   Pekosz, Andrew ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Dimer; Influenza; NS1; Nuclear localization; RNA binding

Indexed keywords

ALANINE; ARGININE; ASPARTIC ACID; LYSINE; NONSTRUCTURAL PROTEIN 1;

AMINO ACID ANALYSIS; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; DIMERIZATION; INFLUENZA VIRUS A; MUTATION; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; VIRUS ISOLATION; VIRUS RECOMBINANT; VIRUS REPLICATION;

DIMER; INFLUENZA; NS1; NUCLEAR LOCALIZATION; RNA BINDING;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; DOGS; GENE EXPRESSION REGULATION, VIRAL; HUMANS; INFLUENZA A VIRUS; MUTAGENESIS, SITE-DIRECTED; MUTATION; NUCLEAR LOCALIZATION SIGNALS; PROTEIN MULTIMERIZATION; PROTEIN TRANSPORT; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 84899801510     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2014.04.012     Document Type: Article

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