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Volumn 127, Issue 5, 2014, Pages 295-306

Protective axis of the renin-angiotensin system in the brain

Author keywords

Angiotensin (1 7); Angiotensin converting enzyme 2 (ACE2); Baroreflex; Hypertension; Mas receptor; Noradrenergic neurotransmission; Renin angiotensin system(RAS)

Indexed keywords

4 AMINOBUTYRIC ACID; ALDOSTERONE; ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR; ANGIOTENSIN[1-7]; BRADYKININ; DOPAMINE; NEUROTRANSMITTER; NORADRENALIN; RENIN; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN I; ANGIOTENSIN I (1-7); DIPEPTIDYL CARBOXYPEPTIDASE; G PROTEIN COUPLED RECEPTOR; ONCOPROTEIN; PEPTIDE FRAGMENT; PROTO-ONCOGENE PROTEINS C-MAS-1;

EID: 84899787539     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20130450     Document Type: Article
Times cited : (63)

References (90)
  • 2
    • 80052037697 scopus 로고    scopus 로고
    • The role of the brain renin-angiotensin system in hypertension: implications for new treatment
    • CrossRef PubMed
    • Marc, Y., and Llorens-Cortes, C. (2011) The role of the brain renin-angiotensin system in hypertension: implications for new treatment. Prog. Neurobiol. 95, 89-103 CrossRef PubMed
    • (2011) Prog. Neurobiol. , vol.95 , pp. 89-103
    • Marc, Y.1    Llorens-Cortes, C.2
  • 3
    • 53749104976 scopus 로고    scopus 로고
    • An intracellular renin-angiotensin system in neurons: fact, hypothesis, or fantasy
    • CrossRef PubMed
    • Grobe, J. L., Xu, D., and Sigmund, C. D. (2008) An intracellular renin-angiotensin system in neurons: fact, hypothesis, or fantasy. Physiology 23, 187-293 CrossRef PubMed
    • (2008) Physiology , vol.23 , pp. 187-293
    • Grobe, J.L.1    Xu, D.2    Sigmund, C.D.3
  • 4
    • 84862537822 scopus 로고    scopus 로고
    • The intracrine renin-angiotensin system
    • CrossRef PubMed
    • Kumar, R., Thomas, C. M., Yong, Q. C., Chen, W., and Baker, K. M. (2012) The intracrine renin-angiotensin system. Clin. Sci. 123, 273-284 CrossRef PubMed
    • (2012) Clin. Sci. , vol.123 , pp. 273-284
    • Kumar, R.1    Thomas, C.M.2    Yong, Q.C.3    Chen, W.4    Baker, K.M.5
  • 5
    • 0025780773 scopus 로고
    • Evidence that prolyl endopeptidase participates in the processing of brain angiotensin
    • CrossRef PubMed
    • Welches, W. R., Santos, R. A., Chappell, M. C., Brosnihan, K. B., Greene, L. J., and Ferrario, C. M. (1991) Evidence that prolyl endopeptidase participates in the processing of brain angiotensin. J. Hypertens. 9, 631-638 CrossRef PubMed
    • (1991) J. Hypertens. , vol.9 , pp. 631-638
    • Welches, W.R.1    Santos, R.A.2    Chappell, M.C.3    Brosnihan, K.B.4    Greene, L.J.5    Ferrario, C.M.6
  • 6
    • 0026605307 scopus 로고
    • In vivo metabolism of angiotensin I by neutral endopeptidase (EC 3.4.24.11) in spontaneously hypertensive rats.
    • CrossRef PubMed
    • Yamamoto, K., Chappell, M. C., Brosnihan, K. B., and Ferrario, C. M. (1992) In vivo metabolism of angiotensin I by neutral endopeptidase (EC 3.4.24.11) in spontaneously hypertensive rats. Hypertension 19, 692-696 CrossRef PubMed
    • (1992) Hypertension , vol.19 , pp. 692-696
    • Yamamoto, K.1    Chappell, M.C.2    Brosnihan, K.B.3    Ferrario, C.M.4
  • 7
    • 34547657601 scopus 로고    scopus 로고
    • Enzymatic pathways of the brain renin-angiotensin system: unsolved problems, and continuing challenges
    • CrossRef PubMed
    • Karamyan, V. T., and Speth, R. C. (2007) Enzymatic pathways of the brain renin-angiotensin system: unsolved problems, and continuing challenges. Regul. Pept. 143, 15-27 CrossRef PubMed
    • (2007) Regul. Pept. , vol.143 , pp. 15-27
    • Karamyan, V.T.1    Speth, R.C.2
  • 10
    • 18544378161 scopus 로고    scopus 로고
    • Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase
    • CrossRef PubMed
    • Vickers, C., Hales, P., Kaushik, V., Dick, L., Gavin, J., Tang, J., Godbout, K., Parsons, T., Baronas, E., Hsieh, F. et al. (2002) Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J. Biol. Chem. 277, 14838-14843 CrossRef PubMed
    • (2002) J. Biol. Chem. , vol.277 , pp. 14838-14843
    • Vickers, C.1    Hales, P.2    Kaushik, V.3    Dick, L.4    Gavin, J.5    Tang, J.6    Godbout, K.7    Parsons, T.8    Baronas, E.9    Hsieh, F.10
  • 11
    • 33846183617 scopus 로고    scopus 로고
    • Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system
    • CrossRef PubMed
    • Doobay, M. F., Talman, L. S., Obr, T. D., Tian, X., Davisson, R. L., and Lazartigues, E. (2007) Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system. Am. J. Physiol. Regul. Integr. Comp. Physiol. 292, R373-R381 CrossRef PubMed
    • (2007) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.292
    • Doobay, M.F.1    Talman, L.S.2    Obr, T.D.3    Tian, X.4    Davisson, R.L.5    Lazartigues, E.6
  • 12
    • 33644861536 scopus 로고    scopus 로고
    • Distinct roles for ANG II, and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes
    • CrossRef PubMed
    • Gallagher, P. E., Chappell, M. C., Ferrario, C. M., and Tallant, E. A. (2006) Distinct roles for ANG II, and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes. Am. J. Physiol. Cell Physiol. 290, C420-C426 CrossRef PubMed
    • (2006) Am. J. Physiol. Cell Physiol. , vol.290
    • Gallagher, P.E.1    Chappell, M.C.2    Ferrario, C.M.3    Tallant, E.A.4
  • 13
    • 0024150774 scopus 로고
    • Immunocytochemical localization of angiotensin-(1-7) in the rat forebrain
    • CrossRef PubMed
    • Block, C. H., Santos, R. A., Brosnihan, K. B., and Ferrario, C. M. (1988) Immunocytochemical localization of angiotensin-(1-7) in the rat forebrain. Peptides 9, 1395-1401 CrossRef PubMed
    • (1988) Peptides , vol.9 , pp. 1395-1401
    • Block, C.H.1    Santos, R.A.2    Brosnihan, K.B.3    Ferrario, C.M.4
  • 14
    • 62649166390 scopus 로고    scopus 로고
    • Angiotensin-(1-7) through AT2 receptors mediates tyrosine hydroxylase degradation via the ubiquitin-proteasome pathway
    • CrossRef PubMed
    • Lopez Verrilli, M. A., Pirola, C. J., Pascual, M. M., Dominici, F. P., Turyn, D., and Gironacci, M. M. (2009) Angiotensin-(1-7) through AT2 receptors mediates tyrosine hydroxylase degradation via the ubiquitin-proteasome pathway. J. Neurochem. 109, 326-335 CrossRef PubMed
    • (2009) J. Neurochem. , vol.109 , pp. 326-335
    • Lopez Verrilli, M.A.1    Pirola, C.J.2    Pascual, M.M.3    Dominici, F.P.4    Turyn, D.5    Gironacci, M.M.6
  • 15
    • 84867567647 scopus 로고    scopus 로고
    • The brain renin-angiotensin system, and cardiovascular responses to stress: insights from transgenic rats with low brain angiotensinogen
    • CrossRef PubMed
    • Arnold, A. C., Sakima, A., Kasper, S. O., Vinsant, S., Garcia-Espinosa, M. A., and Diz, D. I. (2012) The brain renin-angiotensin system, and cardiovascular responses to stress: insights from transgenic rats with low brain angiotensinogen. J. Appl. Physiol. 113, 1929-1936 CrossRef PubMed
    • (2012) J. Appl. Physiol. , vol.113 , pp. 1929-1936
    • Arnold, A.C.1    Sakima, A.2    Kasper, S.O.3    Vinsant, S.4    Garcia-Espinosa, M.A.5    Diz, D.I.6
  • 16
    • 0024445978 scopus 로고
    • Identification of angiotensin-(1-7) in rat brain.Evidence for differential processing of angiotensin peptides.
    • PubMed
    • Chappell, M. C., Brosnihan, K. B., Diz, D. I., and Ferrario, C. M. (1989) Identification of angiotensin-(1-7) in rat brain. Evidence for differential processing of angiotensin peptides. J. Biol. Chem. 264, 16518-16523 PubMed
    • (1989) J. Biol. Chem. , vol.264 , pp. 16518-16523
    • Chappell, M.C.1    Brosnihan, K.B.2    Diz, D.I.3    Ferrario, C.M.4
  • 23
    • 84859438307 scopus 로고    scopus 로고
    • Immunohistochemical localization of the angiotensin-(1-7) receptor Mas in the murine forebrain
    • CrossRef PubMed
    • Freund, M., Walther, T., and von Bohlen und Halbach, O. (2012) Immunohistochemical localization of the angiotensin-(1-7) receptor Mas in the murine forebrain. Cell Tissue Res. 348, 29-35 CrossRef PubMed
    • (2012) Cell Tissue Res. , vol.348 , pp. 29-35
    • Freund, M.1    Walther, T.2    von Bohlen und Halbach, O.3
  • 25
    • 0028258843 scopus 로고
    • Functional organization of central pathways regulating the cardiovascular system
    • PubMed
    • Dampney, R. A. (1994) Functional organization of central pathways regulating the cardiovascular system. Physiol. Rev. 74, 323-364 PubMed
    • (1994) Physiol. Rev. , vol.74 , pp. 323-364
    • Dampney, R.A.1
  • 26
  • 27
    • 0036563174 scopus 로고    scopus 로고
    • Differential effects of angiotensin II, and angiotensin-(1-7) at the nucleus tractus solitarii of transgenic rats with low brain angiotensinogen
    • CrossRef PubMed
    • Couto, A. S., Baltatu, O., Santos, R. A., Ganten, D., Bader, M., and Campagnole-Santos, M. J. (2002) Differential effects of angiotensin II, and angiotensin-(1-7) at the nucleus tractus solitarii of transgenic rats with low brain angiotensinogen. J. Hypertens. 20, 919-925 CrossRef PubMed
    • (2002) J. Hypertens. , vol.20 , pp. 919-925
    • Couto, A.S.1    Baltatu, O.2    Santos, R.A.3    Ganten, D.4    Bader, M.5    Campagnole-Santos, M.J.6
  • 28
    • 3543131800 scopus 로고    scopus 로고
    • Baroreceptors, and the long-term control of blood pressure
    • CrossRef PubMed
    • Thrasher, T. N. (2004) Baroreceptors, and the long-term control of blood pressure. Exp. Physiol. 89, 331-335 CrossRef PubMed
    • (2004) Exp. Physiol. , vol.89 , pp. 331-335
    • Thrasher, T.N.1
  • 29
    • 84878087757 scopus 로고    scopus 로고
    • Neuromodulatory role of angiotensin-(1-7) in the central nervous system
    • CrossRef PubMed
    • Gironacci, M. M., Longo Carbajosa, N., Goldstein, J., and Cerrato, B. D. (2013) Neuromodulatory role of angiotensin-(1-7) in the central nervous system. Clin. Sci. 125, 57-65 CrossRef PubMed
    • (2013) Clin. Sci. , vol.125 , pp. 57-65
    • Gironacci, M.M.1    Longo Carbajosa, N.2    Goldstein, J.3    Cerrato, B.D.4
  • 30
    • 0030004176 scopus 로고    scopus 로고
    • Changes in the baroreflex control of heart rate produced by central infusion of selective angiotensin antagonists in hypertensive rats
    • CrossRef PubMed
    • Oliveira, D. R., Santos, R. A., Santos, G. F., Khosla, M., and Campagnole-Santos, M. J. (1996) Changes in the baroreflex control of heart rate produced by central infusion of selective angiotensin antagonists in hypertensive rats. Hypertension 27, 1284-1290 CrossRef PubMed
    • (1996) Hypertension , vol.27 , pp. 1284-1290
    • Oliveira, D.R.1    Santos, R.A.2    Santos, G.F.3    Khosla, M.4    Campagnole-Santos, M.J.5
  • 31
    • 42349089333 scopus 로고    scopus 로고
    • Modulation of reflex function by endogenous angiotensins in older transgenic rats with low glial angiotensinogen
    • CrossRef PubMed
    • Arnold, A. C., Sakima, A., Ganten, D., Ferrario, C. M., and Diz, D. I. (2008) Modulation of reflex function by endogenous angiotensins in older transgenic rats with low glial angiotensinogen. Hypertension 51, 1326-1331 CrossRef PubMed
    • (2008) Hypertension , vol.51 , pp. 1326-1331
    • Arnold, A.C.1    Sakima, A.2    Ganten, D.3    Ferrario, C.M.4    Diz, D.I.5
  • 32
    • 53249156551 scopus 로고    scopus 로고
    • Angiotensin-(1-7), and baroreflex function in nucleus tractus solitarii of (mRen2)27 transgenic rats
    • CrossRef PubMed
    • Diz, D. I., Garcia-Espinosa, M. A., Gallagher, P. E., Ganten, D., Ferrario, C. M., and Averill, D. B. (2008) Angiotensin-(1-7), and baroreflex function in nucleus tractus solitarii of (mRen2)27 transgenic rats. J. Cardiovasc. Pharmacol. 51, 542-548 CrossRef PubMed
    • (2008) J. Cardiovasc. Pharmacol. , vol.51 , pp. 542-548
    • Diz, D.I.1    Garcia-Espinosa, M.A.2    Gallagher, P.E.3    Ganten, D.4    Ferrario, C.M.5    Averill, D.B.6
  • 33
    • 84868213185 scopus 로고    scopus 로고
    • Central angiotensin-(1-7) improves vagal function independent of blood pressure in hypertensive (mRen2) 27 rats
    • CrossRef PubMed
    • Nautiyal, M., Shaltout, H. A., de Lima, D. C., do Nascimento, K., Chappell, M. C., and Diz, D. I. (2012) Central angiotensin-(1-7) improves vagal function independent of blood pressure in hypertensive (mRen2) 27 rats. Hypertension 60, 1257-1265 CrossRef PubMed
    • (2012) Hypertension , vol.60 , pp. 1257-1265
    • Nautiyal, M.1    Shaltout, H.A.2    de Lima, D.C.3    do Nascimento, K.4    Chappell, M.C.5    Diz, D.I.6
  • 34
    • 84865577246 scopus 로고    scopus 로고
    • In vivo expression of angiotensin-(1-7) lowers blood pressure, and improves baroreflex function in transgenic (mRen2)27 rats
    • CrossRef PubMed
    • Garcia-Espinosa, M. A., Shaltout, H. A., Gallagher, P. E., Chappell, M. C., and Diz, D. I. (2012) In vivo expression of angiotensin-(1-7) lowers blood pressure, and improves baroreflex function in transgenic (mRen2)27 rats. J. Cardiovasc. Pharmacol. 60, 150-157 CrossRef PubMed
    • (2012) J. Cardiovasc. Pharmacol. , vol.60 , pp. 150-157
    • Garcia-Espinosa, M.A.1    Shaltout, H.A.2    Gallagher, P.E.3    Chappell, M.C.4    Diz, D.I.5
  • 35
    • 82955188119 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition, but not AT1 receptor blockade, in the solitary tract nucleus improves baroreflex sensitivity in anesthetized transgenic hypertensive (mRen2)27 rats
    • CrossRef PubMed
    • Isa, K., Arnold, A. C., Westwood, B. M., Chappell, M. C., and Diz, D. I. (2011) Angiotensin-converting enzyme inhibition, but not AT1 receptor blockade, in the solitary tract nucleus improves baroreflex sensitivity in anesthetized transgenic hypertensive (mRen2)27 rats. Hypertens. Res. 34, 1257-1262 CrossRef PubMed
    • (2011) Hypertens. Res. , vol.34 , pp. 1257-1262
    • Isa, K.1    Arnold, A.C.2    Westwood, B.M.3    Chappell, M.C.4    Diz, D.I.5
  • 36
    • 77956692408 scopus 로고    scopus 로고
    • Altered cardiovascular reflexes responses in conscious angiotensin-(1-7) receptor Mas-knockout mice
    • CrossRef PubMed
    • de Moura, M. M., dos Santos, R. A., Campagnole-Santos, M. J., Todiras, M., Bader, M., Alenina, N., and Haibara, A. S. (2010) Altered cardiovascular reflexes responses in conscious angiotensin-(1-7) receptor Mas-knockout mice. Peptides 31, 1934-1939 CrossRef PubMed
    • (2010) Peptides , vol.31 , pp. 1934-1939
    • de Moura, M.M.1    dos Santos, R.A.2    Campagnole-Santos, M.J.3    Todiras, M.4    Bader, M.5    Alenina, N.6    Haibara, A.S.7
  • 37
    • 84856088086 scopus 로고    scopus 로고
    • Angiotensin-(1-7) deficiency, and baroreflex impairment precede the antenatal Betamethasone exposure-induced elevation in blood pressure
    • CrossRef PubMed
    • Shaltout, H. A., Rose, J. C., Chappell, M. C., and Diz, D. I. (2012) Angiotensin-(1-7) deficiency, and baroreflex impairment precede the antenatal Betamethasone exposure-induced elevation in blood pressure. Hypertension 59, 453-458 CrossRef PubMed
    • (2012) Hypertension , vol.59 , pp. 453-458
    • Shaltout, H.A.1    Rose, J.C.2    Chappell, M.C.3    Diz, D.I.4
  • 38
    • 84875966148 scopus 로고    scopus 로고
    • Fetal betamethasone exposure attenuates angiotensin-(1-7)-Mas receptor expression in the dorsal medulla of adult sheep
    • CrossRef PubMed
    • Marshall, A. C., Shaltout, H. A., Nautiyal, M., Rose, J. C., Chappell, M. C., and Diz, D. I. (2013) Fetal betamethasone exposure attenuates angiotensin-(1-7)-Mas receptor expression in the dorsal medulla of adult sheep. Peptides 44, 25-31 CrossRef PubMed
    • (2013) Peptides , vol.44 , pp. 25-31
    • Marshall, A.C.1    Shaltout, H.A.2    Nautiyal, M.3    Rose, J.C.4    Chappell, M.C.5    Diz, D.I.6
  • 39
  • 40
    • 39149107763 scopus 로고    scopus 로고
    • Hemodynamic effect produced by microinjection of angiotensins at the caudal ventrolateral medulla of spontaneously hypertensive rats
    • CrossRef PubMed
    • Ferreira, P. M., Alzamora, A. C., Santos, R. A., and Campagnole-Santos, M. J. (2008) Hemodynamic effect produced by microinjection of angiotensins at the caudal ventrolateral medulla of spontaneously hypertensive rats. Neuroscience 151, 1208-1216 CrossRef PubMed
    • (2008) Neuroscience , vol.151 , pp. 1208-1216
    • Ferreira, P.M.1    Alzamora, A.C.2    Santos, R.A.3    Campagnole-Santos, M.J.4
  • 41
    • 0036839392 scopus 로고    scopus 로고
    • Hypotensive effect of ANG II, and ANG-(1-7) at the caudal ventrolateral medulla involves different mechanisms
    • PubMed
    • Alzamora, A. C., Santos, R. A., and Campagnole-Santos, M. J. (2002) Hypotensive effect of ANG II, and ANG-(1-7) at the caudal ventrolateral medulla involves different mechanisms. Am. J. Physiol. Regul. Integr. Comp. Physiol. 283, R1187-R1195 PubMed
    • (2002) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.283
    • Alzamora, A.C.1    Santos, R.A.2    Campagnole-Santos, M.J.3
  • 42
    • 0030779799 scopus 로고    scopus 로고
    • Role of angiotensin II receptor subtypes in mediating the sympathoexcitatory effects of exogenous, and endogenous angiotensin peptides in the rostral ventrolateral medulla of the rabbit
    • CrossRef PubMed
    • Hirooka, Y., Potts, P. D., and Dampney, R. A. (1997) Role of angiotensin II receptor subtypes in mediating the sympathoexcitatory effects of exogenous, and endogenous angiotensin peptides in the rostral ventrolateral medulla of the rabbit. Brain Res. 772, 107-114 CrossRef PubMed
    • (1997) Brain Res. , vol.772 , pp. 107-114
    • Hirooka, Y.1    Potts, P.D.2    Dampney, R.A.3
  • 43
    • 0031133781 scopus 로고    scopus 로고
    • Involvement of AT2 receptors at NRVL in tonic baroreflex suppression by endogenous angiotensins
    • PubMed
    • Lin, K. S., Chan, J. Y., and Chan, S. H. (1997) Involvement of AT2 receptors at NRVL in tonic baroreflex suppression by endogenous angiotensins. Am. J. Physiol. 272, H2204-H2210 PubMed
    • (1997) Am. J. Physiol. , vol.272
    • Lin, K.S.1    Chan, J.Y.2    Chan, S.H.3
  • 44
    • 0343472101 scopus 로고    scopus 로고
    • Cardiovascular effects produced by microinjection of angiotensins, and angiotensin antagonists into the ventrolateral medulla of freely moving rats
    • CrossRef PubMed
    • Fontes, M. A., Martins Pinge, M. C., Naves, V., Campagnole-Santos, M. J., Lopes, O. U., Khosla, M. C., and Santos, R. A. (1997) Cardiovascular effects produced by microinjection of angiotensins, and angiotensin antagonists into the ventrolateral medulla of freely moving rats. Brain Res. 750, 305-310 CrossRef PubMed
    • (1997) Brain Res. , vol.750 , pp. 305-310
    • Fontes, M.A.1    Martins Pinge, M.C.2    Naves, V.3    Campagnole-Santos, M.J.4    Lopes, O.U.5    Khosla, M.C.6    Santos, R.A.7
  • 45
    • 0030175583 scopus 로고    scopus 로고
    • Pressor action of angiotensin I at the ventrolateral medulla: effect of selective angiotensinblockade
    • CrossRef PubMed
    • Lima, D. X., Fontes, M. A., Oliveira, R. C., Campagnole-Santos, M. J., Khosla, M. C., and Santos, R. A. (1996) Pressor action of angiotensin I at the ventrolateral medulla: effect of selective angiotensinblockade. Immunopharmacology 33,305-307 CrossRef PubMed
    • (1996) Immunopharmacology , vol.33 , pp. 305-307
    • Lima, D.X.1    Fontes, M.A.2    Oliveira, R.C.3    Campagnole-Santos, M.J.4    Khosla, M.C.5    Santos, R.A.6
  • 46
    • 0028173621 scopus 로고
    • Evidence that angiotensin-(1-7) plays a role in the central control of blood pressure at the ventro-lateral medulla acting through specific receptors
    • CrossRef PubMed
    • Fontes, M. A., Silva, L. C., Campagnole-Santos, M. J., Khosla, M. C., Guertzenstein, P. G., and Santos, R. A. (1994) Evidence that angiotensin-(1-7) plays a role in the central control of blood pressure at the ventro-lateral medulla acting through specific receptors. Brain Res. 665, 175-180 CrossRef PubMed
    • (1994) Brain Res. , vol.665 , pp. 175-180
    • Fontes, M.A.1    Silva, L.C.2    Campagnole-Santos, M.J.3    Khosla, M.C.4    Guertzenstein, P.G.5    Santos, R.A.6
  • 47
    • 84871447881 scopus 로고    scopus 로고
    • Angiotensin II, and angiotensin-(1-7) in paraventricular nucleus modulate cardiac sympathetic afferent reflex in renovascular hypertensive rats
    • CrossRef PubMed
    • Sun, H. J., Li, P., Chen, W. W., Xiong, X. Q., and Han, Y. (2012) Angiotensin II, and angiotensin-(1-7) in paraventricular nucleus modulate cardiac sympathetic afferent reflex in renovascular hypertensive rats. PLoS ONE 7,e52557 CrossRef PubMed
    • (2012) PLoS ONE , vol.7
    • Sun, H.J.1    Li, P.2    Chen, W.W.3    Xiong, X.Q.4    Han, Y.5
  • 48
    • 78651104672 scopus 로고    scopus 로고
    • Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea
    • CrossRef PubMed
    • da Silva, A. Q., Fontes, M. A., and Kanagy, N. L. (2011) Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea. Brain Res. 1368, 231-238 CrossRef PubMed
    • (2011) Brain Res. , vol.1368 , pp. 231-238
    • da Silva, A.Q.1    Fontes, M.A.2    Kanagy, N.L.3
  • 49
    • 0035377324 scopus 로고    scopus 로고
    • The role of the nervous system in hypertension
    • CrossRef
    • Wyss, J. M., and Carlson, S. H. (2001) The role of the nervous system in hypertension. Curr. Hypert. Rep. 3, 255-262 CrossRef
    • (2001) Curr. Hypert. Rep. , vol.3 , pp. 255-262
    • Wyss, J.M.1    Carlson, S.H.2
  • 50
    • 0031592893 scopus 로고    scopus 로고
    • Angiotensin receptors, and norepinephrine neuromodulation: implications of functional coupling
    • CrossRef PubMed
    • Gelband, C. H., Sumners, C., and Raizada, M. K. (1997) Angiotensin receptors, and norepinephrine neuromodulation: implications of functional coupling. Regul. Pept. 72, 139-145 CrossRef PubMed
    • (1997) Regul. Pept. , vol.72 , pp. 139-145
    • Gelband, C.H.1    Sumners, C.2    Raizada, M.K.3
  • 51
    • 23944468012 scopus 로고    scopus 로고
    • In vivo characterization of the angiotensin-(1-7)-induced dopamine, and gamma-aminobutyric acid release in the striatum of the rat
    • CrossRef PubMed
    • Stragier, B., Hristova, I., Sarre, S., Ebinger, G., and Michotte, Y. (2005) In vivo characterization of the angiotensin-(1-7)-induced dopamine, and gamma-aminobutyric acid release in the striatum of the rat. Eur. J. Neurosci. 22, 658-664 CrossRef PubMed
    • (2005) Eur. J. Neurosci. , vol.22 , pp. 658-664
    • Stragier, B.1    Hristova, I.2    Sarre, S.3    Ebinger, G.4    Michotte, Y.5
  • 53
    • 84872875844 scopus 로고    scopus 로고
    • Angiotensin-(1-7) central administration induces anxiolytic-like effects in elevated plus maze, and decreased oxidative stress in the amygdala
    • CrossRef PubMed
    • Bild, W., and Ciobica, A. (2013) Angiotensin-(1-7) central administration induces anxiolytic-like effects in elevated plus maze, and decreased oxidative stress in the amygdala. J. Affect. Disord. 145, 165-171 CrossRef PubMed
    • (2013) J. Affect. Disord. , vol.145 , pp. 165-171
    • Bild, W.1    Ciobica, A.2
  • 55
    • 84868667825 scopus 로고    scopus 로고
    • Suppressing inflammation by inhibiting the NF-?B pathway contributes to the neuroprotective effect of angiotensin-(1-7) in rats with permanent cerebral ischaemia
    • CrossRef PubMed
    • Jiang, T., Gao, L., Guo, J., Lu, J., Wang, Y., and Zhang, Y. (2012) Suppressing inflammation by inhibiting the NF-?B pathway contributes to the neuroprotective effect of angiotensin-(1-7) in rats with permanent cerebral ischaemia. Br. J. Pharmacol. 167, 1520-1532 CrossRef PubMed
    • (2012) Br. J. Pharmacol. , vol.167 , pp. 1520-1532
    • Jiang, T.1    Gao, L.2    Guo, J.3    Lu, J.4    Wang, Y.5    Zhang, Y.6
  • 56
    • 56349133166 scopus 로고    scopus 로고
    • Central administration of angiotensin-(1-7) stimulates nitric oxide release, and upregulates the endothelial nitric oxide synthase expression following focal cerebral ischemia/reperfusion in rats
    • CrossRef PubMed
    • Zhang, Y., Lu, J., Shi, J., Lin, X., Dong, J., Zhang, S., Liu, Y., and Tong, Q. (2008) Central administration of angiotensin-(1-7) stimulates nitric oxide release, and upregulates the endothelial nitric oxide synthase expression following focal cerebral ischemia/reperfusion in rats. Neuropeptides 42, 593-600 CrossRef PubMed
    • (2008) Neuropeptides , vol.42 , pp. 593-600
    • Zhang, Y.1    Lu, J.2    Shi, J.3    Lin, X.4    Dong, J.5    Zhang, S.6    Liu, Y.7    Tong, Q.8
  • 58
    • 84886948916 scopus 로고    scopus 로고
    • The expression of angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas receptor axis are upregulated after acute cerebral ischemic stroke in rats
    • CrossRef PubMed
    • Lu, J., Jiang, T., Wu, L., Gao, L., Wang, Y., Zhou, F., Zhang, S., and Zhang, Y. (2013) The expression of angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas receptor axis are upregulated after acute cerebral ischemic stroke in rats. Neuropeptides 47, 289-295 CrossRef PubMed
    • (2013) Neuropeptides , vol.47 , pp. 289-295
    • Lu, J.1    Jiang, T.2    Wu, L.3    Gao, L.4    Wang, Y.5    Zhou, F.6    Zhang, S.7    Zhang, Y.8
  • 59
    • 84870903418 scopus 로고    scopus 로고
    • Angiotensin-(1-7) modulates renin-angiotensin system associated with reducing oxidative stress, and attenuating neuronal apoptosis in the brain of hypertensive rats
    • CrossRef PubMed
    • Jiang, T., Gao, L., Shi, J., Lu, J., Wang, Y., and Zhang, Y. (2013) Angiotensin-(1-7) modulates renin-angiotensin system associated with reducing oxidative stress, and attenuating neuronal apoptosis in the brain of hypertensive rats. Pharmacol. Res. 67, 84-89 CrossRef PubMed
    • (2013) Pharmacol. Res. , vol.67 , pp. 84-89
    • Jiang, T.1    Gao, L.2    Shi, J.3    Lu, J.4    Wang, Y.5    Zhang, Y.6
  • 60
    • 84876103234 scopus 로고    scopus 로고
    • Angiotensin-(1-7) inhibits autophagy in the brain of spontaneously hypertensive rats
    • CrossRef PubMed
    • Jiang, T., Gao, L., Zhu, X. C., Yu, J. T., Shi, J. Q., Tan, M. S., Lu, J., Tan, L., and Zhang, Y. D. (2013) Angiotensin-(1-7) inhibits autophagy in the brain of spontaneously hypertensive rats. Pharmacol. Res. 71, 61-68 CrossRef PubMed
    • (2013) Pharmacol. Res. , vol.71 , pp. 61-68
    • Jiang, T.1    Gao, L.2    Zhu, X.C.3    Yu, J.T.4    Shi, J.Q.5    Tan, M.S.6    Lu, J.7    Tan, L.8    Zhang, Y.D.9
  • 61
    • 84893669600 scopus 로고    scopus 로고
    • Effects of the angiotensin-(1-7) receptor Mas on cell proliferation and on the population of doublecortin positive cells within the dentate gyrus, and the piriform cortex
    • CrossRef PubMed
    • Freund, M., Walther, T., and von Bohlen Und Halbach, O. (2013) Effects of the angiotensin-(1-7) receptor Mas on cell proliferation, and on the population of doublecortin positive cells within the dentate gyrus, and the piriform cortex. Eur. Neuropsychopharmacol. 24, 302-308 CrossRef PubMed
    • (2013) Eur. Neuropsychopharmacol. , vol.24 , pp. 302-308
    • Freund, M.1    Walther, T.2    Von Bohlen Und Halbach, O.3
  • 62
    • 33947703100 scopus 로고    scopus 로고
    • Angiotensin-(1-7)-induced plasticity changes in the lateral amygdala are mediated by COX-2, and NO
    • CrossRef PubMed
    • Albrecht, D. (2007) Angiotensin-(1-7)-induced plasticity changes in the lateral amygdala are mediated by COX-2, and NO. Learn. Mem. 14, 177-184 CrossRef PubMed
    • (2007) Learn. Mem. , vol.14 , pp. 177-184
    • Albrecht, D.1
  • 63
    • 84863873052 scopus 로고    scopus 로고
    • Angiotensin-(1-7) inhibits neuronal activity of dorsolateral periaqueductal gray via a nitric oxide pathway
    • CrossRef PubMed
    • Xing, J., Kong, J., Lu, J., and Li, J. (2012) Angiotensin-(1-7) inhibits neuronal activity of dorsolateral periaqueductal gray via a nitric oxide pathway. Neurosci. Lett. 522, 156-161 CrossRef PubMed
    • (2012) Neurosci. Lett. , vol.522 , pp. 156-161
    • Xing, J.1    Kong, J.2    Lu, J.3    Li, J.4
  • 64
    • 7244240604 scopus 로고    scopus 로고
    • Angiotensin-(1-7) inhibitory mechanism of norepinephrine release in hypertensive rats
    • CrossRef PubMed
    • Gironacci, M. M., Valera, M. S., Yujnovsky, I., and Peña, C. (2004) Angiotensin-(1-7) inhibitory mechanism of norepinephrine release in hypertensive rats. Hypertension 44, 783-787 CrossRef PubMed
    • (2004) Hypertension , vol.44 , pp. 783-787
    • Gironacci, M.M.1    Valera, M.S.2    Yujnovsky, I.3    Peña, C.4
  • 65
    • 78651375228 scopus 로고    scopus 로고
    • Angiotensin-(1-7) increases neuronal potassium current via a nitric oxide-dependent mechanism
    • CrossRef PubMed
    • Yang, R. F., Yin, J. X., Li, Y. L., Zimmerman, M. C., and Schultz, H. D. (2011) Angiotensin-(1-7) increases neuronal potassium current via a nitric oxide-dependent mechanism. Am. J. Physiol. Cell. Physiol. 300, C58-C64 CrossRef PubMed
    • (2011) Am. J. Physiol. Cell. Physiol. , vol.300
    • Yang, R.F.1    Yin, J.X.2    Li, Y.L.3    Zimmerman, M.C.4    Schultz, H.D.5
  • 66
    • 84875220925 scopus 로고    scopus 로고
    • Angiotensin-(1-7) in the rostral ventrolateral medulla modulates enhanced cardiac sympathetic afferent reflex, and sympathetic activation in renovascular hypertensive rats
    • CrossRef PubMed
    • Li, P., Sun, H. J., Cui, B. P., Zhou, Y. B., and Han, Y. (2013) Angiotensin-(1-7) in the rostral ventrolateral medulla modulates enhanced cardiac sympathetic afferent reflex, and sympathetic activation in renovascular hypertensive rats. Hypertension 61, 820-827 CrossRef PubMed
    • (2013) Hypertension , vol.61 , pp. 820-827
    • Li, P.1    Sun, H.J.2    Cui, B.P.3    Zhou, Y.B.4    Han, Y.5
  • 67
    • 84868355106 scopus 로고    scopus 로고
    • Angiotensin-(1-7) in paraventricular nucleus modulates sympathetic activity, and cardiac sympathetic afferent reflex in renovascular hypertensive rats
    • CrossRef PubMed
    • Han, Y., Sun, H. J., Li, P., Gao, Q., Zhou, Y. B., Zhang, F., Gao, X. Y., and Zhu, G. Q. (2012) Angiotensin-(1-7) in paraventricular nucleus modulates sympathetic activity, and cardiac sympathetic afferent reflex in renovascular hypertensive rats. PLoS ONE 7, e48966 CrossRef PubMed
    • (2012) PLoS ONE , vol.7
    • Han, Y.1    Sun, H.J.2    Li, P.3    Gao, Q.4    Zhou, Y.B.5    Zhang, F.6    Gao, X.Y.7    Zhu, G.Q.8
  • 68
    • 84866490375 scopus 로고    scopus 로고
    • Superoxide anions modulate the effects of angiotensin-(1-7) in the rostral ventrolateral medulla on cardiac sympathetic afferent reflex, and sympathetic activity in rats
    • CrossRef PubMed
    • Li, P., Zhang, F., Zhou, Y. B., Cui, B. P., and Han, Y. (2012) Superoxide anions modulate the effects of angiotensin-(1-7) in the rostral ventrolateral medulla on cardiac sympathetic afferent reflex, and sympathetic activity in rats. Neuroscience 223, 388-398 CrossRef PubMed
    • (2012) Neuroscience , vol.223 , pp. 388-398
    • Li, P.1    Zhang, F.2    Zhou, Y.B.3    Cui, B.P.4    Han, Y.5
  • 69
    • 84863707860 scopus 로고    scopus 로고
    • Renin activates PI3K-Akt-eNOS signalling through the angiotensin AT1, and Mas receptors to modulate central blood pressure control in the nucleus tractus solitarii
    • CrossRef PubMed
    • Cheng, W. H., Lu, P. J., Hsiao, M., Hsiao, C. H., Ho, W. Y., Cheng, P. W., Lin, C. T., Hong, L. Z., and Tseng, C. J. (2012) Renin activates PI3K-Akt-eNOS signalling through the angiotensin AT1, and Mas receptors to modulate central blood pressure control in the nucleus tractus solitarii. Br. J. Pharmacol. 166, 2024-2035 CrossRef PubMed
    • (2012) Br. J. Pharmacol. , vol.166 , pp. 2024-2035
    • Cheng, W.H.1    Lu, P.J.2    Hsiao, M.3    Hsiao, C.H.4    Ho, W.Y.5    Cheng, P.W.6    Lin, C.T.7    Hong, L.Z.8    Tseng, C.J.9
  • 70
    • 84859871006 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2: the first decade
    • CrossRef
    • Clarke, N. E., and Turner, A. J. (2012) Angiotensin-converting enzyme 2: the first decade. Int. J. Hypertens. 2012, 307-315 CrossRef
    • (2012) Int. J. Hypertens. , vol.2012 , pp. 307-315
    • Clarke, N.E.1    Turner, A.J.2
  • 71
    • 38049005632 scopus 로고    scopus 로고
    • Calmodulin interacts with angiotensin-converting enzyme-2 (ACE2), and inhibits shedding of its ectodomain
    • CrossRef PubMed
    • Lambert, D. W., Clarke, N. E., Hooper, N. M., and Turner, A. J. (2008) Calmodulin interacts with angiotensin-converting enzyme-2 (ACE2), and inhibits shedding of its ectodomain. FEBS Lett. 582, 385-390 CrossRef PubMed
    • (2008) FEBS Lett. , vol.582 , pp. 385-390
    • Lambert, D.W.1    Clarke, N.E.2    Hooper, N.M.3    Turner, A.J.4
  • 72
    • 66449111167 scopus 로고    scopus 로고
    • The identification of a calmodulin-binding domain within the cytoplasmic tail of angiotensin-converting enzyme-2
    • CrossRef PubMed
    • Lai, Z. W., Lew, R. A., Yarski, M. A., Mu, F. T.,, Andrews, R. K., and Smith, A. I. (2009) The identification of a calmodulin-binding domain within the cytoplasmic tail of angiotensin-converting enzyme-2. Endocrinology 150, 2376-2381 CrossRef PubMed
    • (2009) Endocrinology , vol.150 , pp. 2376-2381
    • Lai, Z.W.1    Lew, R.A.2    Yarski, M.A.3    Mu, F.T.4    Andrews, R.K.5    Smith, A.I.6
  • 73
    • 24044444558 scopus 로고    scopus 로고
    • Tumor necrosis factor-a convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2)
    • CrossRef PubMed
    • Lambert, D. W., Yarski, M., Warner, F. J., Thornhill, P., Parkin, E. T., Smith, A. I., Hooper, N. M., and Turner, A. J. (2005) Tumor necrosis factor-a convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme- 2 (ACE2). J. Biol. Chem. 280,30113-30119 CrossRef PubMed
    • (2005) J. Biol. Chem. , vol.280 , pp. 30113-30119
    • Lambert, D.W.1    Yarski, M.2    Warner, F.J.3    Thornhill, P.4    Parkin, E.T.5    Smith, A.I.6    Hooper, N.M.7    Turner, A.J.8
  • 74
    • 84886089553 scopus 로고    scopus 로고
    • Brain angiotensin-converting enzyme type 2 shedding contributes to the development of neurogenic hypertension
    • CrossRef PubMed
    • Xia H., Sriramula, S., Chhabra, K. H., and Lazartigues, E. (2013) Brain angiotensin-converting enzyme type 2 shedding contributes to the development of neurogenic hypertension. Circ. Res. 113, 1087-1096 CrossRef PubMed
    • (2013) Circ. Res. , vol.113 , pp. 1087-1096
    • Xia, H.1    Sriramula, S.2    Chhabra, K.H.3    Lazartigues, E.4
  • 76
    • 84886406732 scopus 로고    scopus 로고
    • Newly discovered components, and actions of the renin-angiotensin system
    • CrossRef PubMed
    • Carey, R. M. (2013) Newly discovered components, and actions of the renin-angiotensin system. Hypertension 62, 818-822 CrossRef PubMed
    • (2013) Hypertension , vol.62 , pp. 818-822
    • Carey, R.M.1
  • 77
    • 84862284803 scopus 로고    scopus 로고
    • Targeting the ACE2, and apelin pathways are novel therapies for heart failure: opportunities, and challenges
    • PubMed
    • Kazemi-Bajestani, S. M., Patel, V. B., Wang, W., and Oudit, G. Y. (2012) Targeting the ACE2, and apelin pathways are novel therapies for heart failure: opportunities, and challenges. Cardiol. Res. Pract. 2012,823193 PubMed
    • (2012) Cardiol. Res. Pract. , vol.2012 , pp. 823193
    • Kazemi-Bajestani, S.M.1    Patel, V.B.2    Wang, W.3    Oudit, G.Y.4
  • 78
    • 28844479589 scopus 로고    scopus 로고
    • Apelin: a novel neurohumoral modulator of the cardiovascular system. Pathophysiologic importance, and potential use as a therapeutic target.
    • PubMed
    • Falcao-Pires I. and Leite-Moreira, A. F. (2005) Apelin: a novel neurohumoral modulator of the cardiovascular system. Pathophysiologic importance, and potential use as a therapeutic target. Rev. Port. Cardiol. 24, 1263-1276 PubMed
    • (2005) Rev. Port. Cardiol. , vol.24 , pp. 1263-1276
    • Falcao-Pires, I.1    Leite-Moreira, A.F.2
  • 79
    • 84879838430 scopus 로고    scopus 로고
    • Apelin acts in the subfornical organ to influence neuronal excitability, and cardiovascular function
    • CrossRef PubMed
    • Dai, L., Smith, P. M., Kuksis, M., and Ferguson, A. V. (2013) Apelin acts in the subfornical organ to influence neuronal excitability, and cardiovascular function. J. Physiol. 591, 3421-3432 CrossRef PubMed
    • (2013) J. Physiol. , vol.591 , pp. 3421-3432
    • Dai, L.1    Smith, P.M.2    Kuksis, M.3    Ferguson, A.V.4
  • 80
    • 84865120187 scopus 로고    scopus 로고
    • Apelin-13 protects the brain against ischemic reperfusion injury, and cerebral edema in a transient model of focal cerebral ischemia
    • CrossRef PubMed
    • Khaksari, M., Aboutaleb, N., Nasirinezhad, F., Vakili, A., and Madjd, Z. (2012) Apelin-13 protects the brain against ischemic reperfusion injury, and cerebral edema in a transient model of focal cerebral ischemia. J. Mol. Neurosci. 48, 201-208 CrossRef PubMed
    • (2012) J. Mol. Neurosci. , vol.48 , pp. 201-208
    • Khaksari, M.1    Aboutaleb, N.2    Nasirinezhad, F.3    Vakili, A.4    Madjd, Z.5
  • 82
    • 34047193877 scopus 로고    scopus 로고
    • Overexpression of angiotensin-converting enzyme 2 in the rostral ventrolateral medulla causes long-term decrease in blood pressure in the spontaneously hypertensive rats
    • CrossRef PubMed
    • Yamazato, M., Yamazato, Y., Sun, C., Diez-Freire, C., and Raizada, M. K. (2007) Overexpression of angiotensin-converting enzyme 2 in the rostral ventrolateral medulla causes long-term decrease in blood pressure in the spontaneously hypertensive rats. Hypertension 49, 926-931 CrossRef PubMed
    • (2007) Hypertension , vol.49 , pp. 926-931
    • Yamazato, M.1    Yamazato, Y.2    Sun, C.3    Diez-Freire, C.4    Raizada, M.K.5
  • 83
    • 83455201672 scopus 로고    scopus 로고
    • Gene transfer of angiotensin-converting enzyme 2 in the nucleus tractus solitarius improves baroreceptor heart rate reflex in spontaneously hypertensive rats
    • CrossRef PubMed
    • Yamazato, M., Ferreira, A. J., Yamazato, Y., Diez-Freire, C., Yuan, L., Gillies, R., and Raizada, M. K. (2011) Gene transfer of angiotensin-converting enzyme 2 in the nucleus tractus solitarius improves baroreceptor heart rate reflex in spontaneously hypertensive rats. J. Renin Angiotensin Aldosterone Syst. 12, 456-461 CrossRef PubMed
    • (2011) J. Renin Angiotensin Aldosterone Syst. , vol.12 , pp. 456-461
    • Yamazato, M.1    Ferreira, A.J.2    Yamazato, Y.3    Diez-Freire, C.4    Yuan, L.5    Gillies, R.6    Raizada, M.K.7
  • 84
    • 76349095332 scopus 로고    scopus 로고
    • Brain-selective overexpression of human Angiotensin-converting enzyme type 2 attenuates neurogenic hypertension
    • CrossRef PubMed
    • Feng, Y., Xia, H., Cai, Y., Halabi, C. M., Becker, L. K., Santos, R. A., Speth, R. C., Sigmund, C. D., and Lazartigues, E. (2010) Brain-selective overexpression of human Angiotensin-converting enzyme type 2 attenuates neurogenic hypertension.Circ. Res.,106,373-382 CrossRef PubMed
    • (2010) Circ. Res. , vol.106 , pp. 373-382
    • Feng, Y.1    Xia, H.2    Cai, Y.3    Halabi, C.M.4    Becker, L.K.5    Santos, R.A.6    Speth, R.C.7    Sigmund, C.D.8    Lazartigues, E.9
  • 85
    • 77950591072 scopus 로고    scopus 로고
    • Exercise training normalizes ACE, and ACE2 in the brain of rabbits with pacing-induced heart failure
    • CrossRef PubMed
    • Kar, S., Gao, L., and Zucker, I. H. (2010) Exercise training normalizes ACE, and
    • (2010) J. Appl. Physiol. , vol.108 , pp. 923-932
    • Kar, S.1    Gao, L.2    Zucker, I.H.3
  • 86
    • 83155192160 scopus 로고    scopus 로고
    • Brain-selective overexpression of angiotensin-converting enzyme 2 attenuates sympathetic nerve activity, and enhances baroreflex function in chronic heart failure
    • CrossRef PubMed
    • Xiao, L., Gao, L., Lazartigues, E., and Zucker, I. H. (2011) Brain-selective overexpression of angiotensin-converting enzyme 2 attenuates sympathetic nerve activity, and enhances baroreflex function in chronic heart failure. Hypertension 58, 1057-1065 CrossRef PubMed
    • (2011) Hypertension , vol.58 , pp. 1057-1065
    • Xiao, L.1    Gao, L.2    Lazartigues, E.3    Zucker, I.H.4
  • 87
    • 41449089986 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor, and drinking responses, and is associated with angiotensin II type 1 receptor downregulation
    • CrossRef PubMed
    • Feng, Y., Yue, X., Xia, H., Bindom, S. M., Hickman, P. J., Filipeanu, C. M., Wu, G., and Lazartigues, E. (2008) Angiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor, and drinking responses, and is associated with angiotensin II type 1 receptor downregulation. Circ. Res. 102, 729-736 CrossRef PubMed
    • (2008) Circ. Res. , vol.102 , pp. 729-736
    • Feng, Y.1    Yue, X.2    Xia, H.3    Bindom, S.M.4    Hickman, P.J.5    Filipeanu, C.M.6    Wu, G.7    Lazartigues, E.8
  • 88
    • 81055133082 scopus 로고    scopus 로고
    • ACE2 overexpression in the paraventricular nucleus attenuates angiotensin II-induced hypertension
    • CrossRef PubMed
    • Sriramula, S., Cardinale, J. P., Lazartigues, E., and Francis, J. (2011).ACE2 overexpression in the paraventricular nucleus attenuates angiotensin II-induced hypertension.Cardiovasc. Res.,92,401-408 CrossRef PubMed
    • (2011) Cardiovasc. Res. , vol.92 , pp. 401-408
    • Sriramula, S.1    Cardinale, J.P.2    Lazartigues, E.3    Francis, J.4
  • 89
    • 79960810124 scopus 로고    scopus 로고
    • ACE2-mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function
    • CrossRef PubMed
    • Xia, H., Suda, S., Bindom, S., Feng, Y., Gurley, S. B., Seth, D., Navar, L. G., and Lazartigues, E. (2011) ACE2-mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function. PLoS ONE 6, e22682 CrossRef PubMed
    • (2011) PLoS ONE , vol.6
    • Xia, H.1    Suda, S.2    Bindom, S.3    Feng, Y.4    Gurley, S.B.5    Seth, D.6    Navar, L.G.7    Lazartigues, E.8
  • 90
    • 42649141198 scopus 로고    scopus 로고
    • Injections of angiotensin-converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats
    • CrossRef PubMed
    • Diz, D. I., Garcia-Espinosa, M. A., Gegick, S., Tommasi, E. N., Ferrario, C. M., Ann Tallant, E., Chappell, M. C., and Gallagher, P. E. (2008) Injections of angiotensin-converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats. Exp. Physiol. 93, 694-700 CrossRef PubMed
    • (2008) Exp. Physiol. , vol.93 , pp. 694-700
    • Diz, D.I.1    Garcia-Espinosa, M.A.2    Gegick, S.3    Tommasi, E.N.4    Ferrario, C.M.5    Ann Tallant, E.6    Chappell, M.C.7    Gallagher, P.E.8


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