Superoxide anions modulate the effects of angiotensin-(1-7) in the rostral ventrolateral medulla on cardiac sympathetic afferent reflex and sympathetic activity in rats

Neuroscience

Volumn 223, Issue , 2012, Pages 388-398

  Li, P ^a   Zhang, F ^a   Zhou, Y B ^a   Cui, B P ^a   Han, Y ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Angiotensin (1 7); Cardiovascular reflex; Rostral ventrolateral medulla; Superoxide anions; Sympathetic activity

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN[1-7]; ANGIOTENSIN[1-7][7 DEXTRO ALANINE]; APOCYNIN; CAPSAICIN; G PROTEIN COUPLED RECEPTOR; LOSARTAN; MAS RECEPTOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; TEMPOL; TIRON; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CARDIAC SYMPATHETIC EFFERENT REFLEX; CARDIOVASCULAR REFLEX; CONTROLLED STUDY; ENZYME ACTIVITY; HORMONE ACTION; MALE; MEAN ARTERIAL PRESSURE; MEDULLA OBLONGATA; NERVOUS SYSTEM FUNCTION; NONHUMAN; PRIORITY JOURNAL; RAT; RENAL SYMPATHETIC NERVE ACTIVITY; ROSTRAL VENTROLATERAL MEDULLA; SYMPATHETIC TONE;

AFFERENT PATHWAYS; ANGIOTENSIN I; ANIMALS; ANTIHYPERTENSIVE AGENTS; AUTONOMIC DENERVATION; BLOOD PRESSURE; CAPSAICIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; ENZYME INHIBITORS; HEART RATE; MALE; MEDULLA OBLONGATA; MICROINJECTIONS; NADPH OXIDASE; NG-NITROARGININE METHYL ESTER; OXIDANTS; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; REFLEX; SUPEROXIDES; SYMPATHETIC NERVOUS SYSTEM; VAGOTOMY;

EID: 84866490375     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.07.048     Document Type: Article

References (48)

1. Alzamora A.C., Santos R.A., Campagnole-Santos M.J. Baroreflex modulation by angiotensins at the rat rostral and caudal ventrolateral medulla. Am J Physiol Regul Integr Comp Physiol 2006, 290:R1027-R1034.
2. Badoer E. Hypothalamic paraventricular nucleus and cardiovascular regulation. Clin Exp Pharmacol Physiol 2001, 28:95-99.
3. Bedard K., Krause K.H. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev 2007, 87:245-313.
4. Bourassa E.A., Sved A.F., Speth R.C. Angiotensin modulation of rostral ventrolateral medulla (RVLM) in cardiovascular regulation. Mol Cell Endocrinol 2009, 302:167-175.
5. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254.
6. Cai H., Griendling K.K., Harrison D.G. The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. Trends Pharmacol Sci 2003, 24:471-478.
7. Cassis P., Conti S., Remuzzi G., Benigni A. Angiotensin receptors as determinants of life span. Pflugers Arch 2010, 459:325-332.
8. Chan J.Y., Wang L.L., Wu K.L., Chan S.H. Reduced functional expression and molecular synthesis of inducible nitric oxide synthase in rostral ventrolateral medulla of spontaneously hypertensive rats. Circulation 2001, 104:1676-1681.
9. 1 receptors in paraventricular nucleus contribute to sympathetic activation and enhanced cardiac sympathetic afferent reflex in renovascular hypertensive rats. Exp Physiol 2011, 96:94-103.
10. Du Y.H., Chen A.F. A "love triangle" elicited by electrochemistry: complex interactions among cardiac sympathetic afferent, chemo-, and baroreflexes. J Appl Physiol 2007, 102:9-10.
11. Duan Y.C., Xu B., Shi Z., Gao J., Zhang S.J., Wang W., Chen Q., Zhu G.Q. Nucleus of solitary tract mediates cardiac sympathetic afferent reflex in rats. Pflugers Arch 2009, 459:1-9.
12. Ehlers P.I., Nurmi L., Turpeinen A.M., Korpela R., Vapaatalo H. Casein-derived tripeptide Ile-Pro-Pro improves angiotensin-(1-7)- and bradykinin-induced rat mesenteric artery relaxation. Life Sci 2011, 88:206-211.
13. Esteban V., Heringer-Walther S., Sterner-Kock A., de B.R., van den E.S., Wang Y., Mezzano S., Egido J., Schultheiss H.P., Ruiz-Ortega M., Walther T. Angiotensin-(1-7) and the g protein-coupled receptor MAS are key players in renal inflammation. PLoS ONE 2009, 4:e5406.
14. Ferreira P.M., Alzamora A.C., Santos R.A., Campagnole-Santos M.J. Hemodynamic effect produced by microinjection of angiotensins at the caudal ventrolateral medulla of spontaneously hypertensive rats. Neuroscience 2008, 151:1208-1216.
15. Fontes M.A., Silva L.C., Campagnole-Santos M.J., Khosla M.C., Guertzenstein P.G., Santos R.A. Evidence that angiotensin-(1-7) plays a role in the central control of blood pressure at the ventro-lateral medulla acting through specific receptors. Brain Res. 1994, 665:175-180.
16. Fontes M.A., Baltatu O., Caligiorne S.M., Campagnole-Santos M.J., Ganten D., Bader M., Santos R.A. Angiotensin peptides acting at rostral ventrolateral medulla contribute to hypertension of TGR(mREN2)27 rats. Physiol Genomics 2000, 2:137-142.
17. Gan X.B., Duan Y.C., Xiong X.Q., Li P., Cui B.P., Gao X.Y., Zhu G.Q. Inhibition of cardiac sympathetic afferent reflex and sympathetic activity by baroreceptor and vagal afferent inputs in chronic heart failure. PLoS ONE 2011, 6:e25784.
18. Greenstock C.L., Miller R.W. The oxidation of tiron by superoxide anion. Kinetics of the reaction in aqueous solution in chloroplasts. Biochim Biophys Acta 1975, 396:11-16.
19. Gu R., Lu W., Xie J., Bai J., Xu B. Renalase deficiency in heart failure model of rats - a potential mechanism underlying circulating norepinephrine accumulation. PLoS ONE 2011, 6:e14633.
20. Guyenet P.G., Haselton J.R., Sun M.K. Sympathoexcitatory neurons of the rostroventrolateral medulla and the origin of the sympathetic vasomotor tone. Prog Brain Res 1989, 81:105-116.
21. Han Y., Zhang Y., Wang H.J., Gao X.Y., Wang W., Zhu G.Q. Reactive oxygen species in paraventricular nucleus modulates cardiac sympathetic afferent reflex in rats. Brain Res 2005, 1058:82-90.
22. Han Y., Shi Z., Zhang F., Yu Y., Zhong M.K., Gao X.Y., Wang W., Zhu G.Q. Reactive oxygen species in the paraventricular nucleus mediate the cardiac sympathetic afferent reflex in chronic heart failure rats. Eur J Heart Fail 2007, 9:967-973.
23. Han Y., Fan Z.D., Yuan N., Xie G.Q., Gao J., De W., Gao X.Y., Zhu G.Q. Superoxide anions in paraventricular nucleus mediate the enhanced cardiac sympathetic afferent reflex and sympathetic activity in renovascular hypertensive rats. J Appl Physiol 2011, 110:646-652.
24. Han Y., Yuan N., Zhang S.J., Gao J., Shi Z., Zhou Y.B., Gao X.Y., Zhu G.Q. C-Src in paraventricular nucleus modulates sympathetic activity and cardiac sympathetic afferent reflex in renovascular hypertensive rats. Pflugers Arch 2011, 461:437-446.
25. Jiang M.Y., Chen J., Wang J., Xiao F., Zhang H.H., Zhang C.R., Du D.S., Cao Y.X., Shen L.L., Zhu D.N. Nitric oxide modulates cardiovascular function in the rat by activating adenosine A2A receptors and inhibiting acetylcholine release in the rostral ventrolateral medulla. Clin Exp Pharmacol Physiol 2011, 38:380-386.
26. Lauar M.R., Colombari D.S., De Paula P.M., Colombari E., Cardoso L.M., De L.L., Menani J.V. Inhibition of central angiotensin II-induced pressor responses by hydrogen peroxide. Neuroscience 2010, 171:524-530.
27. Ma R., Zucker I.H., Wang W. Reduced NO enhances the central gain of cardiac sympathetic afferent reflex in dogs with heart failure. Am J Physiol 1999, 276:H19-H26.
28. Malliani A., Montano N. Emerging excitatory role of cardiovascular sympathetic afferents in pathophysiological conditions. Hypertension 2002, 39:63-68.
29. Mancia G., Grassi G., Giannattasio C., Seravalle G. Sympathetic activation in the pathogenesis of hypertension and progression of organ damage. Hypertension 1999, 34:724-728.
30. Nakagaki T., Hirooka Y., Ito K., Kishi T., Hoka S., Sunagawa K. Role of angiotensin-(1-7) in rostral ventrolateral medulla in blood pressure regulation via sympathetic nerve activity in Wistar-Kyoto and spontaneous hypertensive rats. Clin Exp Hypertens 2011, 33:223-230.
31. Qi Y., Shenoy V., Wong F., Li H., Afzal A., Mocco J., Sumners C., Raizada M.K., Katovich M.J. Lentivirus-mediated overexpression of angiotensin-(1-7) attenuated ischaemia-induced cardiac pathophysiology. Exp Physiol 2011, 96:863-874.
32. Santos R.A., Haibara A.S., Campagnole-Santos M.J., Simoes e Silva A.C., Paula R.D., Pinheiro S.V., Leite M.F., Lemos V.S., Silva D.M., Guerra M.T., Khosla M.C. Characterization of a new selective antagonist for angiotensin-(1-7), D-pro7-angiotensin-(1-7). Hypertension 2003, 41:737-743.
33. Santos R.A., Simoes e Silva A.C., Maric C., Silva D.M., Machado R.P., de B.I., Heringer-Walther S., Pinheiro S.V., Lopes M.T., Bader M., Mendes E.P., Lemos V.S., Campagnole-Santos M.J., Schultheiss H.P., Speth R., Walther T. Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc Natl Acad Sci USA 2003, 100:8258-8263.
34. Santos R.A., Ferreira A.J., Simoes e Silva A.C. Recent advances in the angiotensin-converting enzyme 2-angiotensin(1-7)-Mas axis. Exp Physiol 2008, 93:519-527.
35. Shi Z., Chen A.D., Xu Y., Chen Q., Gao X.Y., Wang W., Zhu G.Q. Long-term administration of tempol attenuates postinfarct ventricular dysfunction and sympathetic activity in rats. Pflugers Arch 2009, 458:247-257.
36. Silva-Barcellos N.M., Frezard F., Caligiorne S., Santos R.A. Long-lasting cardiovascular effects of liposome-entrapped angiotensin-(1-7) at the rostral ventrolateral medulla. Hypertension 2001, 38:1266-1271.
37. Wang W., Ma R. Cardiac sympathetic afferent reflexes in heart failure. Heart Fail Rev 2000, 5:57-71.
38. 2+, and protein kinase C play a role in angiotensin II-induced free radical production in nucleus tractus solitarius. Hypertension 2006, 48:482-489.
39. Yamada J., Yoshimura S., Yamakawa H., Sawada M., Nakagawa M., Hara S., Kaku Y., Iwama T., Naganawa T., Banno Y., Nakashima S., Sakai N. Cell permeable ROS scavengers, Tiron and Tempol, rescue PC12 cell death caused by pyrogallol or hypoxia/reoxygenation. Neurosci Res 2003, 45:1-8.
40. Zhang Y., Yu Y., Zhang F., Zhong M.K., Shi Z., Gao X.Y., Wang W., Zhu G.Q. NAD(P)H oxidase in paraventricular nucleus contributes to the effect of angiotensin II on cardiac sympathetic afferent reflex. Brain Res 2006, 1082:132-141.
41. Zhang M., Mao Y., Ramirez S.H., Tuma R.F., Chabrashvili T. Angiotensin II induced cerebral microvascular inflammation and increased blood-brain barrier permeability via oxidative stress. Neuroscience 2010, 171:852-858.
42. Zhong M.K., Duan Y.C., Chen A.D., Xu B., Gao X.Y., De W., Zhu G.Q. Paraventricular nucleus is involved in the central pathway of cardiac sympathetic afferent reflex in rats. Exp Physiol 2008, 93:746-753.
43. Zhong M.K., Shi Z., Zhou L.M., Gao J., Liao Z.H., Wang W., Gao X.Y., Zhu G.Q. Regulation of cardiac sympathetic afferent reflex by GABAA and GABAB receptors in paraventricular nucleus in rats. Eur J Neurosci 2008, 27:3226-3232.
44. Zhong M.K., Gao J., Zhang F., Xu B., Fan Z.D., Wang W., Zhu G.Q. Reactive oxygen species in rostral ventrolateral medulla modulate cardiac sympathetic afferent reflex in rats. Acta Physiol (Oxf) 2009, 197:297-304.
45. Zhou L.M., Shi Z., Gao J., Han Y., Yuan N., Gao X.Y., Zhu G.Q. Angiotensin-(1-7) and angiotension II in the rostral ventrolateral medulla modulate the cardiac sympathetic afferent reflex and sympathetic activity in rats. Pflugers Arch 2010, 459:681-688.
46. Zhu G.Q., Xu Y., Zhou L.M., Li Y.H., Fan L.M., Wang W., Gao X.Y., Chen Q. Enhanced cardiac sympathetic afferent reflex involved in sympathetic overactivity in renovascular hypertensive rats. Exp Physiol 2009, 94:785.
47. Zimmerman M.C. Angiotensin II and angiotensin-1-7 redox signaling in the central nervous system. Curr Opin Pharmacol 2011, 11:138-143.
48. Zucker I.H., Pliquett R.U. Novel mechanisms of sympatho-excitation in chronic heart failure. Heart Fail Monit 2002, 3:2-7.