Human-specific epigenetic variation in the immunological Leukotriene B4 Receptor (LTB4R/BLT1) implicated in common inflammatory diseases

Genome Medicine

Volumn 6, Issue 3, 2014, Pages

  Wilson, Gareth A ^a,e   Butcher, Lee M ^a   Foster, Holly R ^b   Feber, Andrew ^a   Roos, Christian ^c   Walter, Lutz ^c   Woszczek, Grzegorz ^b   Beck, Stephan ^a   Bell, Christopher G ^a,d  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c GERMAN PRIMATE CENTER   (Germany)

^d ST THOMAS HOSPITAL   (United Kingdom)

^e CRUK London Research Institute   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; LEUKOTRIENE B4; LEUKOTRIENE B4 RECEPTOR; LIGAND; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CTCF;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CHROMATIN; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DNA METHYLOME; DNA STRUCTURE; EPIGENETICS; EXON; FEMALE; GENE; GENE BODY METHYLATION; GENE EXPRESSION; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC DIFFERENCE; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN SPECIES SPECIFIC DIFFERENTIALLY METHYLATED REGION; HUMAN SPECIFIC EPIGENETIC VARIATION; IMMUNOPATHOGENESIS; INFLAMMATORY DISEASE; INNATE IMMUNITY; LEUKOTRIENE B4 RECEPTOR GENE; LYMPHOBLASTOID H3K4ME3 CHROMATIN; MALE; NEUTROPHIL; NONHUMAN; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; RHESUS MONKEY; SIGNAL TRANSDUCTION; SPECIES COMPARISON; SPECIES DIFFERENCE; TRANSCRIPTION FACTOR BINDING SITE MOTIF; CHIMPANZEE; HUMAN VERSUS ANIMAL COMPARISON; LYMPHOBLASTOID CELL; PROTEIN EXPRESSION; PROTEIN MOTIF;

EID: 84899650618     PISSN: None     EISSN: 1756994X     Source Type: Journal    
DOI: 10.1186/gm536     Document Type: Article

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