Zinc modulates high glucose-induced apoptosis by suppressing oxidative stress in renal tubular epithelial cells

Biological Trace Element Research

Volumn 158, Issue 2, 2014, Pages 259-267

  Zhang, Xiuli ^a,b   Zhao, Yue ^a   Chu, Qingqing ^a   Wang, Zhan You ^c   Li, Hongjuan ^d   Chi, Zhi Hong ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b Benxi Central Hospital   (China)

^c NORTHEASTERN UNIVERSITY   (China)

^d Troops of 95935 Unit   (China)

Author keywords

Apoptosis; High glucose; NF E2 related factor 2; Renal tubular epithelial cells; Zinc

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; GLUCOSE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE PEROXIDASE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXIDOREDUCTASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN KINASE B; QUINONE OXIDOREDUCTASE 1; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ZINC SULFATE; ZINC;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL SURVIVAL; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXICITY; DIABETIC NEPHROPATHY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; EPITHELIUM CELL; INTRACELLULAR SIGNALING; KIDNEY TUBULE CELL; NONHUMAN; OXIDATIVE STRESS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; SUPPLEMENTATION; UPREGULATION; ANIMAL; CELL CULTURE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; KIDNEY TUBULE; METABOLISM; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; GLUCOSE; KIDNEY TUBULES; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; ZINC;

EID: 84899643302     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-014-9922-x     Document Type: Article

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