Pycnogenol modulates apoptosis by suppressing oxidative stress and inflammation in high glucose-treated renal tubular cells

Food and Chemical Toxicology

Volumn 49, Issue 9, 2011, Pages 2196-2201

  Kim, You Jung ^a   Kim, Young Ae ^b   Yokozawa, Takako ^b  

^a Department of Dental Hygiene   (South Korea)

^b UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Apoptosis; Diabetic nephropathy; Inflammation; Oxidative stress; Pycnogenol

Indexed keywords

CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PEROXYNITRITE; PROTEIN BAX; PROTEIN BCL 2; PYCNOGENOL; PYCOGENOL; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL LYSATE; CELL NUCLEUS; CELL PROTECTION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DIABETIC NEPHROPATHY; DOWN REGULATION; DRUG EFFECT; HUMAN; HUMAN CELL; KIDNEY TUBULE CELL; LIPID PEROXIDATION; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SUPERNATANT; UPREGULATION;

APOPTOSIS; FLAVONOIDS; GLUCOSE; INFLAMMATION; KIDNEY TUBULES; OXIDATIVE STRESS;

EID: 79960838959     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.06.012     Document Type: Article

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