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Volumn 20, Issue 8, 2013, Pages 998-1007

Mcl-1 antagonizes Bax/Bak to promote effector CD4+ and CD8 + T-cell responses

Author keywords

Bak; Bax; Bcl 2; Bim; Mcl 1; T cells

Indexed keywords

BIM PROTEIN; MYELOID CELL LEUKEMIA SEQUENCE 1; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN NOXA; PUMA PROTEIN; UNCLASSIFIED DRUG;

EID: 84880279718     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2013.25     Document Type: Article
Times cited : (44)

References (48)
  • 1
    • 0033607506 scopus 로고    scopus 로고
    • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
    • Bouillet P, Metcalf D, Huang DC, Tarlinton DM, Kay TW, Kontgen F et al. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 1999; 286: 1735-1738.
    • (1999) Science , vol.286 , pp. 1735-1738
    • Bouillet, P.1    Metcalf, D.2    Huang, D.C.3    Tarlinton, D.M.4    Kay, T.W.5    Kontgen, F.6
  • 3
    • 0027527099 scopus 로고
    • Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice
    • Nakayama K, Nakayama K, Negishi I, Kuida K, Shinkai Y, Louie MC et al. Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice. Science 1993; 261: 1584-1588.
    • (1993) Science , vol.261 , pp. 1584-1588
    • Nakayama, K.1    Nakayama, K.2    Negishi, I.3    Kuida, K.4    Shinkai, Y.5    Louie, M.C.6
  • 4
    • 0027427492 scopus 로고
    • Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
    • Veis DJ, Sorenson CM, Shutter JR, Korsmeyer SJ. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 1993; 75: 229-240.
    • (1993) Cell , vol.75 , pp. 229-240
    • Veis, D.J.1    Sorenson, C.M.2    Shutter, J.R.3    Korsmeyer, S.J.4
  • 5
    • 13844319184 scopus 로고    scopus 로고
    • Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells
    • Opferman JT, Iwasaki H, Ong CC, Suh H, Mizuno S, Akashi K et al. Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells. Science 2005; 307: 1101-1104.
    • (2005) Science , vol.307 , pp. 1101-1104
    • Opferman, J.T.1    Iwasaki, H.2    Ong, C.C.3    Suh, H.4    Mizuno, S.5    Akashi, K.6
  • 7
    • 77953769199 scopus 로고    scopus 로고
    • Contracting the 'mus cells'-does downsizing suit us for diving into the memory pool?
    • Kurtulus S, Tripathi P, Opferman JT, Hildeman DA. Contracting the 'mus cells'-does downsizing suit us for diving into the memory pool? Immunol Rev 2010; 236: 54-67.
    • (2010) Immunol Rev , vol.236 , pp. 54-67
    • Kurtulus, S.1    Tripathi, P.2    Opferman, J.T.3    Hildeman, D.A.4
  • 8
    • 62049084023 scopus 로고    scopus 로고
    • Surviving the crash: Transitioning from effector to memory CD8+ T cell
    • D'Cruz LM, Rubinstein MP, Goldrath AW. Surviving the crash: transitioning from effector to memory CD8+ T cell. Semin Immunol 2009; 21: 92-98.
    • (2009) Semin Immunol , vol.21 , pp. 92-98
    • D'Cruz, L.M.1    Rubinstein, M.P.2    Goldrath, A.W.3
  • 9
    • 33748641378 scopus 로고    scopus 로고
    • Role of Bim in Regulating CD8+ T-cell responses during chronic viral infection
    • Grayson JM,Weant AE, Holbrook BC, Hildeman D. Role of Bim in Regulating CD8+ T-cell responses during chronic viral infection. J Virol 2006; 80: 8627-8638.
    • (2006) J Virol , vol.80 , pp. 8627-8638
    • Grayson Jmweant, A.E.1    Holbrook, B.C.2    Hildeman, D.3
  • 10
  • 11
    • 55949124305 scopus 로고    scopus 로고
    • Exploring regulatory mechanisms of CD8+ T cell contraction
    • Prlic M, Bevan MJ. Exploring regulatory mechanisms of CD8+ T cell contraction. Proc Natl Acad Sci USA 2008; 105: 16689-16694.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16689-16694
    • Prlic, M.1    Bevan, M.J.2
  • 14
    • 40749105745 scopus 로고    scopus 로고
    • Proapoptotic Bcl-2 family member Bim promotes persistent infection and limits protective immunity
    • Reckling S, Divanovic S, Karp CL, Wojciechowski S, Belkaid Y, Hildeman D. Proapoptotic Bcl-2 family member Bim promotes persistent infection and limits protective immunity. Infect Immun 2008; 76: 1179-1185.
    • (2008) Infect Immun , vol.76 , pp. 1179-1185
    • Reckling, S.1    Divanovic, S.2    Karp, C.L.3    Wojciechowski, S.4    Belkaid, Y.5    Hildeman, D.6
  • 15
    • 0347382593 scopus 로고    scopus 로고
    • Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
    • Kaech SM, Tan JT, Wherry EJ, Konieczny BT, Surh CD, Ahmed R. Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat Immunol 2003; 4: 1191-1198.
    • (2003) Nat Immunol , vol.4 , pp. 1191-1198
    • Kaech, S.M.1    Tan, J.T.2    Wherry, E.J.3    Konieczny, B.T.4    Surh, C.D.5    Ahmed, R.6
  • 16
    • 0033561753 scopus 로고    scopus 로고
    • Bystander virus infection prolongs activated T cell survival
    • Mitchell T, Kappler J, Marrack P. Bystander virus infection prolongs activated T cell survival. J Immunol 1999; 162: 4527-4535.
    • (1999) J Immunol , vol.162 , pp. 4527-4535
    • Mitchell, T.1    Kappler, J.2    Marrack, P.3
  • 17
    • 18944372860 scopus 로고    scopus 로고
    • The antiapoptotic protein Bcl-xL is dispensable for the development of effector and memory T lymphocytes
    • Zhang N, He YW. The antiapoptotic protein Bcl-xL is dispensable for the development of effector and memory T lymphocytes. J Immunol 2005; 174: 6967-6973.
    • (2005) J Immunol , vol.174 , pp. 6967-6973
    • Zhang, N.1    He, Y.W.2
  • 20
    • 80055023382 scopus 로고    scopus 로고
    • Cytokine-dependent and cytokine-independent roles for Mcl-1: Genetic evidence for multiple mechanisms by which Mcl-1 promotes survival in primary T lymphocytes
    • Dunkle A, Dzhagalov I, He YW. Cytokine-dependent and cytokine-independent roles for Mcl-1: genetic evidence for multiple mechanisms by which Mcl-1 promotes survival in primary T lymphocytes. Cell Death Dis 2011; 2: e214.
    • (2011) Cell Death Dis , vol.2
    • Dunkle, A.1    Dzhagalov, I.2    He, Y.W.3
  • 21
  • 22
    • 0029163387 scopus 로고
    • CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL
    • Boise LH, Minn AJ, Noel PJ, June CH, Accavitti MA, Lindsten T et al. CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity 1995; 3: 87-98.
    • (1995) Immunity , vol.3 , pp. 87-98
    • Boise, L.H.1    Minn, A.J.2    Noel, P.J.3    June, C.H.4    Accavitti, M.A.5    Lindsten, T.6
  • 24
    • 47949126029 scopus 로고    scopus 로고
    • The anti-apoptotic Bcl-2 family member Mcl-1 promotes T lymphocyte survival at multiple stages
    • Dzhagalov I, Dunkle A, He YW. The anti-apoptotic Bcl-2 family member Mcl-1 promotes T lymphocyte survival at multiple stages. J Immunol 2008; 181: 521-528.
    • (2008) J Immunol , vol.181 , pp. 521-528
    • Dzhagalov, I.1    Dunkle, A.2    He, Y.W.3
  • 28
    • 84861627801 scopus 로고    scopus 로고
    • Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration
    • Perciavalle RM, Stewart DP, Koss B, Lynch J, Milasta S, Bathina M et al. Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration. Nat Cell Biol 2012; 14: 575-583.
    • (2012) Nat Cell Biol , vol.14 , pp. 575-583
    • Perciavalle, R.M.1    Stewart, D.P.2    Koss, B.3    Lynch, J.4    Milasta, S.5    Bathina, M.6
  • 29
    • 19944432123 scopus 로고    scopus 로고
    • Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
    • Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG et al. Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol Cell 2005; 17: 393-403.
    • (2005) Mol Cell , vol.17 , pp. 393-403
    • Chen, L.1    Willis, S.N.2    Wei, A.3    Smith, B.J.4    Fletcher, J.I.5    Hinds, M.G.6
  • 31
    • 2542501399 scopus 로고    scopus 로고
    • Degradation of Mcl-1 by granzyme B: Implications for Bim-mediated mitochondrial apoptotic events
    • Han J, Goldstein LA, Gastman BR, Froelich CJ, Yin XM, Rabinowich H. Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events. J Biol Chem 2004; 279: 22020-22029.
    • (2004) J Biol Chem , vol.279 , pp. 22020-22029
    • Han, J.1    Goldstein, L.A.2    Gastman, B.R.3    Froelich, C.J.4    Yin, X.M.5    Rabinowich, H.6
  • 32
    • 78649273276 scopus 로고    scopus 로고
    • Prevention of cytokine withdrawalinduced apoptosis by Mcl-1 requires interaction between Mcl-1 and Bim
    • Jamil S, Wang SW, Bondy L, Mojtabavi S, Duronio V. Prevention of cytokine withdrawalinduced apoptosis by Mcl-1 requires interaction between Mcl-1 and Bim. Biochem Cell Biol 2010; 88: 809-818.
    • (2010) Biochem Cell Biol , vol.88 , pp. 809-818
    • Jamil, S.1    Wang, S.W.2    Bondy, L.3    Mojtabavi, S.4    Duronio, V.5
  • 33
    • 0034663829 scopus 로고    scopus 로고
    • TBID, a membranetargeted death ligand, oligomerizes BAK to release cytochrome c
    • Wei MC, Lindsten T, Mootha VK, Weiler S, Gross A, Ashiya M et al. tBID, a membranetargeted death ligand, oligomerizes BAK to release cytochrome c. Genes Dev 2000; 14: 2060-2071.
    • (2000) Genes Dev , vol.14 , pp. 2060-2071
    • Wei, M.C.1    Lindsten, T.2    Mootha, V.K.3    Weiler, S.4    Gross, A.5    Ashiya, M.6
  • 34
    • 22244464818 scopus 로고    scopus 로고
    • Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins
    • Willis SN, Chen L, Dewson G, Wei A, Naik E, Fletcher JI et al. Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins. Genes Dev 2005; 19: 1294-1305.
    • (2005) Genes Dev , vol.19 , pp. 1294-1305
    • Willis, S.N.1    Chen, L.2    Dewson, G.3    Wei, A.4    Naik, E.5    Fletcher, J.I.6
  • 35
    • 21244472965 scopus 로고    scopus 로고
    • Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis
    • Zhong Q, Gao W, Du F, Wang X. Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis. Cell 2005; 121: 1085-1095.
    • (2005) Cell , vol.121 , pp. 1085-1095
    • Zhong, Q.1    Gao, W.2    Du, F.3    Wang, X.4
  • 36
    • 34248152731 scopus 로고    scopus 로고
    • Unrestrained glycogen synthase kinase-3 beta activity leads to activated T cell death and can be inhibited by natural adjuvant
    • Sengupta S, Jayaraman P, Chilton PM, Casella CR, Mitchell TC. Unrestrained glycogen synthase kinase-3 beta activity leads to activated T cell death and can be inhibited by natural adjuvant. J Immunol 2007; 178: 6083-6091.
    • (2007) J Immunol , vol.178 , pp. 6083-6091
    • Sengupta, S.1    Jayaraman, P.2    Chilton, P.M.3    Casella, C.R.4    Mitchell, T.C.5
  • 38
    • 33750628289 scopus 로고    scopus 로고
    • Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia
    • Konopleva M, Contractor R, Tsao T, Samudio I, Ruvolo PP, Kitada S et al. Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia. Cancer Cell 2006; 10: 375-388.
    • (2006) Cancer Cell , vol.10 , pp. 375-388
    • Konopleva, M.1    Contractor, R.2    Tsao, T.3    Samudio, I.4    Ruvolo, P.P.5    Kitada, S.6
  • 39
    • 33750834023 scopus 로고    scopus 로고
    • The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/ Bax if Mcl-1 is neutralized
    • van Delft MF, Wei AH, Mason KD, Vandenberg CJ, Chen L, Czabotar PE et al. The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/ Bax if Mcl-1 is neutralized. Cancer Cell 2006; 10: 389-399.
    • (2006) Cancer Cell , vol.10 , pp. 389-399
    • Van Delft, M.F.1    Wei, A.H.2    Mason, K.D.3    Vandenberg, C.J.4    Chen, L.5    Czabotar, P.E.6
  • 40
    • 67649198526 scopus 로고    scopus 로고
    • The Bcl-2 family antagonist ABT-737 significantly inhibits multiple animal models of autoimmunity
    • Bardwell PD, Gu J, McCarthy D, Wallace C, Bryant S, Goess C et al. The Bcl-2 family antagonist ABT-737 significantly inhibits multiple animal models of autoimmunity. J Immunol 2009; 182: 7482-7489.
    • (2009) J Immunol , vol.182 , pp. 7482-7489
    • Bardwell, P.D.1    Gu, J.2    McCarthy, D.3    Wallace, C.4    Bryant, S.5    Goess, C.6
  • 41
    • 77954649027 scopus 로고    scopus 로고
    • BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs
    • Carrington EM, Vikstrom IB, Light A, Sutherland RM, Londrigan SL, Mason KD et al. BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs. Proc Natl Acad Sci USA 2010; 107: 10967-10971.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 10967-10971
    • Carrington, E.M.1    Vikstrom, I.B.2    Light, A.3    Sutherland, R.M.4    Londrigan, S.L.5    Mason, K.D.6
  • 42
    • 0024297793 scopus 로고
    • Isotypic exclusion of gamma delta T cell receptors in transgenic mice bearing a rearranged beta-chain gene
    • Fenton RG, Marrack P, Kappler JW, Kanagawa O, Seidman JG. Isotypic exclusion of gamma delta T cell receptors in transgenic mice bearing a rearranged beta-chain gene. Science 1988; 241: 1089-1092.
    • (1988) Science , vol.241 , pp. 1089-1092
    • Fenton, R.G.1    Marrack, P.2    Kappler, J.W.3    Kanagawa, O.4    Seidman, J.G.5
  • 43
    • 1842301028 scopus 로고    scopus 로고
    • Vaccination against persistent viral infection exacerbates CD4+ T-cell-mediated immunopathological disease
    • Hildeman D, Yanez D, Pederson K, Havighurst T, Muller D. Vaccination against persistent viral infection exacerbates CD4+ T-cell-mediated immunopathological disease. J Virol 1997; 71: 9672-9678.
    • (1997) J Virol , vol.71 , pp. 9672-9678
    • Hildeman, D.1    Yanez, D.2    Pederson, K.3    Havighurst, T.4    Muller, D.5
  • 45
    • 0032101405 scopus 로고    scopus 로고
    • Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes
    • Crawford F, Kozono H, White J, Marrack P, Kappler J. Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes. Immunity 1998; 8: 675-682.
    • (1998) Immunity , vol.8 , pp. 675-682
    • Crawford, F.1    Kozono, H.2    White, J.3    Marrack, P.4    Kappler, J.5
  • 46
    • 0033578388 scopus 로고    scopus 로고
    • An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro
    • Rees W, Bender J, Teague TK, Kedl RM, Crawford F, Marrack P et al. An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro. Proc Natl Acad Sci USA 1999; 96: 9781-9786.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 9781-9786
    • Rees, W.1    Bender, J.2    Teague, T.K.3    Kedl, R.M.4    Crawford, F.5    Marrack, P.6
  • 48
    • 0037221289 scopus 로고    scopus 로고
    • Ablation of CD8 and CD4 T cell responses by high viral loads
    • Fuller MJ, Zajac AJ. Ablation of CD8 and CD4 T cell responses by high viral loads. J Immunol 2003; 170: 477-486.
    • (2003) J Immunol , vol.170 , pp. 477-486
    • Fuller, M.J.1    Zajac, A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.