-
1
-
-
84876078566
-
The CAMKK2-AMPK kinase pathway mediates the synaptotoxic effects of Aβ oligomers through tau phosphorylation
-
Mairet-Coello G, Courchet J, Pieraut S, Courchet V, Maximov A and Polleux F: The CAMKK2-AMPK kinase pathway mediates the synaptotoxic effects of Aβ oligomers through tau phosphorylation. Neuron 78: 94-108, 2013.
-
(2013)
Neuron
, vol.78
, pp. 94-108
-
-
Mairet-Coello, G.1
Courchet, J.2
Pieraut, S.3
Courchet, V.4
Maximov, A.5
Polleux, F.6
-
2
-
-
43249124363
-
Microtubule-associated protein tau in development, degeneration and protection of neurons
-
Wang JZ and Liu F: Microtubule-associated protein tau in development, degeneration and protection of neurons. Prog Neurobiol 85: 148-175, 2008.
-
(2008)
Prog Neurobiol
, vol.85
, pp. 148-175
-
-
Wang, J.Z.1
Liu, F.2
-
3
-
-
84870566969
-
Preclinical sporadic Alzheimer's disease: Target for personalized diagnosis and preventive intervention
-
Vanitallie TB: Preclinical sporadic Alzheimer's disease: target for personalized diagnosis and preventive intervention. Metabolism 62 (Suppl 1): S30-S33, 2013.
-
(2013)
Metabolism
, vol.62
, Issue.SUPPL. 1
-
-
Vanitallie, T.B.1
-
4
-
-
78650215509
-
Regulation of β cleavage of amyloid precursor protein
-
Wang JF, Lu R and Wang YZ: Regulation of β cleavage of amyloid precursor protein. Neurosci Bull 26: 417-427, 2010.
-
(2010)
Neurosci Bull
, vol.26
, pp. 417-427
-
-
Wang, J.F.1
Lu, R.2
Wang, Y.Z.3
-
5
-
-
79955044494
-
Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration
-
Jin M, Shepardson N, Yang T, Chen G, Walsh D and Selkoe DJ: Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration. Proc Natl Acad Sci USA 108: 5819-5824, 2011.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 5819-5824
-
-
Jin, M.1
Shepardson, N.2
Yang, T.3
Chen, G.4
Walsh, D.5
Selkoe, D.J.6
-
6
-
-
34548264782
-
Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease
-
Palop JJ, Chin J, Roberson ED, et al: Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron 55: 697-711, 2007.
-
(2007)
Neuron
, vol.55
, pp. 697-711
-
-
Palop, J.J.1
Chin, J.2
Roberson, E.D.3
-
7
-
-
84873469666
-
Nutrient sensing, metabolism, and cell growth control
-
Yuan HX, Xiong Y and Guan KL: Nutrient sensing, metabolism, and cell growth control. Mol Cell 49: 379-387, 2013.
-
(2013)
Mol Cell
, vol.49
, pp. 379-387
-
-
Yuan, H.X.1
Xiong, Y.2
Guan, K.L.3
-
8
-
-
84865545599
-
LKB1 and AMP-activated protein kinase: Regulators of cell polarity
-
Nakano A and Takashima S: LKB1 and AMP-activated protein kinase: regulators of cell polarity. Genes Cells 17: 737-747, 2012.
-
(2012)
Genes Cells
, vol.17
, pp. 737-747
-
-
Nakano, A.1
Takashima, S.2
-
9
-
-
79960566233
-
AMP-activated protein kinase: A potential player in Alzheimer's disease
-
Salminen A, Kaarniranta K, Haapasalo A, Soininen H and Hiltunen M: AMP-activated protein kinase: a potential player in Alzheimer's disease. J Neurochem 118: 460-474, 2011.
-
(2011)
J Neurochem
, vol.118
, pp. 460-474
-
-
Salminen, A.1
Kaarniranta, K.2
Haapasalo, A.3
Soininen, H.4
Hiltunen, M.5
-
10
-
-
84861738869
-
Neuropathogenic role of adenylate kinase-1 in Aβ-mediated tau phosphorylation via AMPK and GSK3β
-
Park H, Kam TI, Kim Y, et al: Neuropathogenic role of adenylate kinase-1 in Aβ-mediated tau phosphorylation via AMPK and GSK3β. Hum Mol Genet 21: 2725-2737, 2012.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 2725-2737
-
-
Park, H.1
Kam, T.I.2
Kim, Y.3
-
11
-
-
80053383272
-
AMPK activation inhibits apoptosis and tau hyperphosphorylation mediated by palmitate in SH-SY5Y cells
-
Kim J, Park YJ, Jang Y and Kwon YH: AMPK activation inhibits apoptosis and tau hyperphosphorylation mediated by palmitate in SH-SY5Y cells. Brain Res 1418: 42-51, 2011.
-
(2011)
Brain Res
, vol.1418
, pp. 42-51
-
-
Kim, J.1
Park, Y.J.2
Jang, Y.3
Kwon, Y.H.4
-
12
-
-
79952135316
-
AMPK is abnormally activated in tangle-and pre-tangle-bearing neurons in Alzheimer's disease and other tauopathies
-
Vingtdeux V, Davies P, Dickson DW and Marambaud P: AMPK is abnormally activated in tangle-and pre-tangle-bearing neurons in Alzheimer's disease and other tauopathies. Acta Neuropathol 121: 337-349, 2011.
-
(2011)
Acta Neuropathol
, vol.121
, pp. 337-349
-
-
Vingtdeux, V.1
Davies, P.2
Dickson, D.W.3
Marambaud, P.4
-
15
-
-
44049108170
-
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression
-
Hébert SS, Horré K, Nicolaï L, et al: Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression. Proc Natl Acad Sci USA 105: 6415-6420, 2008.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 6415-6420
-
-
Hébert, S.S.1
Horré, K.2
Nicolaï, L.3
-
16
-
-
44349088251
-
MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary
-
Leucht C, Stigloher C, Wizenmann A, Klafke R, Folchert A and Bally-Cuif L: MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary. Nat Neurosci 11: 641-648, 2008.
-
(2008)
Nat Neurosci
, vol.11
, pp. 641-648
-
-
Leucht, C.1
Stigloher, C.2
Wizenmann, A.3
Klafke, R.4
Folchert, A.5
Bally-Cuif, L.6
-
17
-
-
84864778051
-
Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-β
-
Schonrock N, Humphreys DT, Preiss T and Götz J: Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-β. J Mol Neurosci 46: 324-335, 2012.
-
(2012)
J Mol Neurosci
, vol.46
, pp. 324-335
-
-
Schonrock, N.1
Humphreys, D.T.2
Preiss, T.3
Götz, J.4
-
18
-
-
77956195348
-
Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-beta
-
Schonrock N, Ke YD, Humphreys D, et al: Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-beta. PLoS One 5: e11070, 2010.
-
(2010)
PLoS One
, vol.5
-
-
Schonrock, N.1
Ke, Y.D.2
Humphreys, D.3
-
19
-
-
77949393847
-
Protein phosphatase 2A facilitates axonogenesis by dephosphorylating CRMP2
-
Zhu LQ, Zheng HY, Peng CX, et al: Protein phosphatase 2A facilitates axonogenesis by dephosphorylating CRMP2. J Neurosci 30: 3839-3848, 2010.
-
(2010)
J Neurosci
, vol.30
, pp. 3839-3848
-
-
Zhu, L.Q.1
Zheng, H.Y.2
Peng, C.X.3
-
20
-
-
33751088552
-
Stimulation of AMP-activated protein kinase is essential for the induction of drug metabolizing enzymes by phenobarbital in human and mouse liver
-
Rencurel F, Foretz M, Kaufmann MR, et al: Stimulation of AMP-activated protein kinase is essential for the induction of drug metabolizing enzymes by phenobarbital in human and mouse liver. Mol Pharmacol 70: 1925-1934, 2006.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1925-1934
-
-
Rencurel, F.1
Foretz, M.2
Kaufmann, M.R.3
-
21
-
-
84877271133
-
Correlation of specific amyloid-β oligomers with tau in cerebrospinal fluid from cognitively normal older adults
-
Handoko M, Grant M, Kuskowski M, et al: Correlation of specific amyloid-β oligomers with tau in cerebrospinal fluid from cognitively normal older adults. JAMA Neurol 5: 594-599, 2013.
-
(2013)
JAMA Neurol
, vol.5
, pp. 594-599
-
-
Handoko, M.1
Grant, M.2
Kuskowski, M.3
-
22
-
-
84882270859
-
Hypoxia increases Aβ-induced tau phosphorylation by calpain and promotes behavioral consequences in AD transgenic mice
-
Gao L, Tian S, Gao H and Xu Y: Hypoxia increases Aβ-induced tau phosphorylation by calpain and promotes behavioral consequences in AD transgenic mice. J Mol Neurosci 51: 128-147, 2013.
-
(2013)
J Mol Neurosci
, vol.51
, pp. 128-147
-
-
Gao, L.1
Tian, S.2
Gao, H.3
Xu, Y.4
-
23
-
-
84877879701
-
Amyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease
-
Seward ME, Swanson E, Norambuena A, et al: Amyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease. J Cell Sci 126: 1278-1286, 2013.
-
(2013)
J Cell Sci
, vol.126
, pp. 1278-1286
-
-
Seward, M.E.1
Swanson, E.2
Norambuena, A.3
-
24
-
-
79952135798
-
AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure
-
Thornton C, Bright NJ, Sastre M, Muckett PJ and Carling D: AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure. Biochem J 434: 503-512, 2011.
-
(2011)
Biochem J
, vol.434
, pp. 503-512
-
-
Thornton, C.1
Bright, N.J.2
Sastre, M.3
Muckett, P.J.4
Carling, D.5
-
25
-
-
83855162740
-
Phosphorylation of microtubule-associated protein tau by AMPK-related kinases
-
Yoshida H and Goedert M: Phosphorylation of microtubule-associated protein tau by AMPK-related kinases. J Neurochem 120: 165-176, 2012.
-
(2012)
J Neurochem
, vol.120
, pp. 165-176
-
-
Yoshida, H.1
Goedert, M.2
-
27
-
-
84879656519
-
Abnormal interaction of oligomeric amyloid-β with phosphorylated tau: Implications to synaptic dysfunction and neuronal damage
-
Manczak M and Reddy PH: Abnormal interaction of oligomeric amyloid-β with phosphorylated tau: implications to synaptic dysfunction and neuronal damage. J Alzheimers Dis 36: 285-295, 2013.
-
(2013)
J Alzheimers Dis
, vol.36
, pp. 285-295
-
-
Manczak, M.1
Reddy, P.H.2
-
28
-
-
63849085094
-
Targeting the AMPK pathway for the treatment of Type 2 diabetes
-
Landmark Ed
-
Viollet B, Lantier L, Devin-Leclerc J, et al: Targeting the AMPK pathway for the treatment of Type 2 diabetes. Front Biosci (Landmark Ed) 14: 3380-3400, 2009.
-
(2009)
Front Biosci
, vol.14
, pp. 3380-3400
-
-
Viollet, B.1
Lantier, L.2
Devin-Leclerc, J.3
-
29
-
-
84857253827
-
Roles of AMP-activated protein kinase in Alzheimer's disease
-
Cai Z, Yan LJ, Li K, Quazi SH and Zhao B: Roles of AMP-activated protein kinase in Alzheimer's disease. Neuromolecular Med 14: 1-14, 2012.
-
(2012)
Neuromolecular Med
, vol.14
, pp. 1-14
-
-
Cai, Z.1
Yan, L.J.2
Li, K.3
Quazi, S.H.4
Zhao, B.5
-
30
-
-
77957933189
-
Quercetin activates AMP-activated protein kinase by reducing PP2C expression protecting old mouse brain against high cholesterol-induced neurotoxicity
-
Lu J, Wu DM, Zheng YL, et al: Quercetin activates AMP-activated protein kinase by reducing PP2C expression protecting old mouse brain against high cholesterol-induced neurotoxicity. J Pathol 222: 199-212, 2010.
-
(2010)
J Pathol
, vol.222
, pp. 199-212
-
-
Lu, J.1
Wu, D.M.2
Zheng, Y.L.3
-
31
-
-
33847203593
-
Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus
-
Lukiw WJ: Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus. Neuroreport 18: 297-300, 2007.
-
(2007)
Neuroreport
, vol.18
, pp. 297-300
-
-
Lukiw, W.J.1
-
32
-
-
84874609290
-
MicroRNA-195 protects against dementia induced by chronic brain hypoperfusion via its anti-amyloidogenic effect in rats
-
Ai J, Sun LH, Che H, et al: MicroRNA-195 protects against dementia induced by chronic brain hypoperfusion via its anti-amyloidogenic effect in rats. J Neurosci 33: 3989-4001, 2013.
-
(2013)
J Neurosci
, vol.33
, pp. 3989-4001
-
-
Ai, J.1
Sun, L.H.2
Che, H.3
-
33
-
-
59049087888
-
MicroRNA-298 and microRNA-328 regulate expression of mouse beta-amyloid precursor protein-converting enzyme 1
-
Boissonneault V, Plante I, Rivest S and Provost P: MicroRNA-298 and microRNA-328 regulate expression of mouse beta-amyloid precursor protein-converting enzyme 1. J Biol Chem 284: 1971-1981, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 1971-1981
-
-
Boissonneault, V.1
Plante, I.2
Rivest, S.3
Provost, P.4
-
34
-
-
84855806746
-
MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice
-
Liu W, Liu C, Zhu J, et al: MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice. Neurobiol Aging 33: 522-534, 2012.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 522-534
-
-
Liu, W.1
Liu, C.2
Zhu, J.3
-
35
-
-
61349110680
-
MicroRNA regulation of Alzheimer's Amyloid precursor protein expression
-
Hébert SS, Horré K, Nicolaï L, et al: MicroRNA regulation of Alzheimer's Amyloid precursor protein expression. Neurobiol Dis 33: 422-428, 2009.
-
(2009)
Neurobiol Dis
, vol.33
, pp. 422-428
-
-
Hébert, S.S.1
Horré, K.2
Nicolaï, L.3
-
36
-
-
47849124269
-
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways
-
Cogswell JP, Ward J, Taylor IA, et al: Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. J Alzheimers Dis 14: 27-41, 2008.
-
(2008)
J Alzheimers Dis
, vol.14
, pp. 27-41
-
-
Cogswell, J.P.1
Ward, J.2
Taylor, I.A.3
-
37
-
-
84870242919
-
MicroRNA9 regulates neural stem cell differentiation by controlling Hes1 expression dynamics in the developing brain
-
Tan SL, Ohtsuka T, González A and Kageyama R: MicroRNA9 regulates neural stem cell differentiation by controlling Hes1 expression dynamics in the developing brain. Genes Cells 17: 952-961, 2012.
-
(2012)
Genes Cells
, vol.17
, pp. 952-961
-
-
Tan, S.L.1
Ohtsuka, T.2
González, A.3
Kageyama, R.4
|