메뉴 건너뛰기




Volumn 62, Issue SUPPL.1, 2013, Pages

Preclinical sporadic Alzheimer's disease: Target for personalized diagnosis and preventive intervention

Author keywords

Apolipoprotein E 4; Cerebral metabolic rate of glucose; Fluorodeoxyglucose positron emission tomography; Neuroimaging biomarkers; Personalized medicine

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E4; FLUORODEOXYGLUCOSE;

EID: 84870566969     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2012.08.024     Document Type: Article
Times cited : (41)

References (33)
  • 1
    • 84863185648 scopus 로고    scopus 로고
    • Short-term clinical outcomes for stages of NIA-AA preclinical Alzheimer disease
    • D.S. Knopman, C.R. Jack Jr., and H.J. Wiste Short-term clinical outcomes for stages of NIA-AA preclinical Alzheimer disease Neurology 78 2012 1576 1582
    • (2012) Neurology , vol.78 , pp. 1576-1582
    • Knopman, D.S.1    Jack, Jr.C.R.2    Wiste, H.J.3
  • 2
    • 0029013727 scopus 로고
    • Staging of Alzheimer's disease-related neurofibrillary changes
    • H. Braak, and E. Braak Staging of Alzheimer's disease-related neurofibrillary changes Neurobiol Aging 16 1995 271 278
    • (1995) Neurobiol Aging , vol.16 , pp. 271-278
    • Braak, H.1    Braak, E.2
  • 3
    • 80054831349 scopus 로고    scopus 로고
    • Alzheimer Association report 2011: Alzheimer's disease facts and figures
    • Alzheimer Association report 2011: Alzheimer's disease facts and figures Alzheimers Dement 7 2011 208 244
    • (2011) Alzheimers Dement , vol.7 , pp. 208-244
  • 4
    • 2542502430 scopus 로고    scopus 로고
    • ApoE genotype accounts for the vast majority of risk and AD pathology
    • J. Raber, Y. Huang, and J.W. Ashford ApoE genotype accounts for the vast majority of risk and AD pathology Neurobiol Aging 25 2004 641 650
    • (2004) Neurobiol Aging , vol.25 , pp. 641-650
    • Raber, J.1    Huang, Y.2    Ashford, J.W.3
  • 5
    • 84862911656 scopus 로고    scopus 로고
    • Apolipoprotein e promotes β-amyloid trafficking and degradation by modulating microglial cholesterol levels
    • C.Y. Lee, W. Tse, J.D. Smith, and G.E. Landreth Apolipoprotein E promotes β-amyloid trafficking and degradation by modulating microglial cholesterol levels J Biol Chem 287 2012 2032 2044
    • (2012) J Biol Chem , vol.287 , pp. 2032-2044
    • Lee, C.Y.1    Tse, W.2    Smith, J.D.3    Landreth, G.E.4
  • 7
    • 78650678688 scopus 로고    scopus 로고
    • Decreased clearance of CNS beta-amyloid in Alzheimer's disease
    • [Epub 2010 Dec 9]
    • K.G. Mawuenyega, W. Sigurdson, and V. Ovod Decreased clearance of CNS beta-amyloid in Alzheimer's disease Science 330 6012 2010 1774 [Epub 2010 Dec 9]
    • (2010) Science , vol.330 , Issue.6012 , pp. 1774
    • Mawuenyega, K.G.1    Sigurdson, W.2    Ovod, V.3
  • 8
    • 84861112667 scopus 로고    scopus 로고
    • APOE ε4 status and traumatic brain injury on the gridiron or the battlefield
    • S. Gandy, and S.T. DeKosky APOE ε4 status and traumatic brain injury on the gridiron or the battlefield Sci Transl Med 4 134 2012 134ed4
    • (2012) Sci Transl Med , vol.4 , Issue.134
    • Gandy, S.1    Dekosky, S.T.2
  • 9
    • 80051553765 scopus 로고    scopus 로고
    • The dynamics of cortical and hippocampal atrophy in Alzheimer disease
    • M.R. Subuncu, R.S. Desikan, and J. Sepulcre The dynamics of cortical and hippocampal atrophy in Alzheimer disease Arch Neurol 68 2011 1040 1048
    • (2011) Arch Neurol , vol.68 , pp. 1040-1048
    • Subuncu, M.R.1    Desikan, R.S.2    Sepulcre, J.3
  • 10
    • 79955478596 scopus 로고    scopus 로고
    • Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults
    • B.C. Dickerson, T.R. Stoub, and R.C. Shah Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults Neurology 76 2011 1395 1402
    • (2011) Neurology , vol.76 , pp. 1395-1402
    • Dickerson, B.C.1    Stoub, T.R.2    Shah, R.C.3
  • 11
    • 84856966847 scopus 로고    scopus 로고
    • Structural MRI changes detectable up to ten years before clinical Alzheimer's disease
    • M. Tondelli, G.K. Wilcock, and P. Nichelli Structural MRI changes detectable up to ten years before clinical Alzheimer's disease Neurobiol Aging 33 2012 825.e25 825.e36
    • (2012) Neurobiol Aging , vol.33
    • Tondelli, M.1    Wilcock, G.K.2    Nichelli, P.3
  • 12
    • 79960645134 scopus 로고    scopus 로고
    • Sensitivity and specificity of medial temporal lobe visual ratings and multivariate regional MRI classification in Alzheimer's disease
    • [Epub 2011 July 21.]
    • E. Westman, L. Cavallin, and J.S. Muehlboeck Sensitivity and specificity of medial temporal lobe visual ratings and multivariate regional MRI classification in Alzheimer's disease PloS ONE 6 7 2011 e22506 [Epub 2011 July 21.]
    • (2011) PloS ONE , vol.6 , Issue.7 , pp. 22506
    • Westman, E.1    Cavallin, L.2    Muehlboeck, J.S.3
  • 13
    • 80055037882 scopus 로고    scopus 로고
    • Presence of ApoE ε4 allele associated with thinner frontal cortex in middle age
    • C. Fennema-Notestine, M.S. Panizzon, and W.R. Thompson Presence of ApoE ε4 allele associated with thinner frontal cortex in middle age J Alzheimers Dis 26 Suppl. 3 2011 49 60
    • (2011) J Alzheimers Dis , vol.26 , Issue.SUPPL. 3 , pp. 49-60
    • Fennema-Notestine, C.1    Panizzon, M.S.2    Thompson, W.R.3
  • 14
    • 80053632325 scopus 로고    scopus 로고
    • Structural brain changes in normal individuals with a maternal history of Alzheimer's
    • V. Berti, L. Mosconi, and L. Glodzik Structural brain changes in normal individuals with a maternal history of Alzheimer's Neurobiol Aging 32 12 2011 2325.e17 2325.e26
    • (2011) Neurobiol Aging , vol.32 , Issue.12
    • Berti, V.1    Mosconi, L.2    Glodzik, L.3
  • 15
    • 17844364259 scopus 로고    scopus 로고
    • Brain glucose metabolism in the early and specific diagnosis of Alzhiemer's disease. FDG-PET studies in MCI and AD
    • L. Mosconi Brain glucose metabolism in the early and specific diagnosis of Alzhiemer's disease. FDG-PET studies in MCI and AD. Eur J Nucl Med Mol Imaging 32 2005 486 510
    • (2005) Eur J Nucl Med Mol Imaging , vol.32 , pp. 486-510
    • Mosconi, L.1
  • 16
    • 84859718265 scopus 로고    scopus 로고
    • Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
    • K. Talbot, H.-Y. Wang, and H. Kazi Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline J Clin Invest 122 2012 1316 1338
    • (2012) J Clin Invest , vol.122 , pp. 1316-1338
    • Talbot, K.1    Wang, H.-Y.2    Kazi, H.3
  • 17
    • 38049050725 scopus 로고    scopus 로고
    • Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease
    • Y. Liu, F. Liu, K. Iqbal, I. Grundke-Iqbal, and C.-X. Gong Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease FEBS Lett 582 2008 359 364
    • (2008) FEBS Lett , vol.582 , pp. 359-364
    • Liu, Y.1    Liu, F.2    Iqbal, K.3    Grundke-Iqbal, I.4    Gong, C.-X.5
  • 18
    • 84865422160 scopus 로고    scopus 로고
    • A tale of two tracers: Glucose metabolism and amyloid positron emission tomography imaging in Alzheimer's disease
    • J.W. Ashford, IOS Press
    • L. Mosconi, V. Berti, and P. McHugh A tale of two tracers: glucose metabolism and amyloid positron emission tomography imaging in Alzheimer's disease J.W. Ashford, Handbook of imaging the Alzheimer brain 2011 IOS Press 219 234
    • (2011) Handbook of Imaging the Alzheimer Brain , pp. 219-234
    • Mosconi, L.1    Berti, V.2    McHugh, P.3
  • 19
    • 0035845499 scopus 로고    scopus 로고
    • Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/positron-emission tomography (FDG/PET)
    • M.J. de Leon, A. Convit, and O.T. Wolf Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/positron- emission tomography (FDG/PET) Proc Natl Acad Sci USA 98 2001 10966 10971
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10966-10971
    • De Leon, M.J.1    Convit, A.2    Wolf, O.T.3
  • 20
    • 37649001373 scopus 로고    scopus 로고
    • Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism
    • L. Mosconi Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism Proc Natl Acad Sci USA 104 2007 19067 19072
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 19067-19072
    • Mosconi, L.1
  • 21
    • 83255181779 scopus 로고    scopus 로고
    • Amyloid-beta plaque growth in cognitively normal adults: Longitudinal [11C]Pittsburgh compound B data
    • A.G. Vlassenko, M.A. Mintun, and C. Xiong Amyloid-beta plaque growth in cognitively normal adults: longitudinal [11C]Pittsburgh compound B data Ann Neurol 70 2011 857 861
    • (2011) Ann Neurol , vol.70 , pp. 857-861
    • Vlassenko, A.G.1    Mintun, M.A.2    Xiong, C.3
  • 22
    • 80054909832 scopus 로고    scopus 로고
    • Using positron emission tomography and florbetapir F18 to image cortical amyloid in patients with mild cognitive impairment or dementia due to Alzheimer disease
    • A.S. Fleisher, K. Chen, and X. Liu Using positron emission tomography and florbetapir F18 to image cortical amyloid in patients with mild cognitive impairment or dementia due to Alzheimer disease Arch Neurol 68 2011 1404 1411
    • (2011) Arch Neurol , vol.68 , pp. 1404-1411
    • Fleisher, A.S.1    Chen, K.2    Liu, X.3
  • 23
    • 84870561765 scopus 로고    scopus 로고
    • Apolipoprotein e ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease
    • [in press]
    • A.S. Fleisher, K. Chen, and X. Liu Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease Neurobiol Aging 2012 [in press]
    • (2012) Neurobiol Aging
    • Fleisher, A.S.1    Chen, K.2    Liu, X.3
  • 25
    • 84856397420 scopus 로고    scopus 로고
    • Role of family history for Alzheimer biomarker abnormalities in the adult children study
    • C. Xiong, C.M. Roe, and V. Buckles Role of family history for Alzheimer biomarker abnormalities in the adult children study Arch Neurol 68 2011 1313 1319
    • (2011) Arch Neurol , vol.68 , pp. 1313-1319
    • Xiong, C.1    Roe, C.M.2    Buckles, V.3
  • 26
    • 84861910400 scopus 로고    scopus 로고
    • Guidelines for the management of cognitive and behavioral problems in dementia
    • C.H. Sadowsky, and J.E. Galvin Guidelines for the management of cognitive and behavioral problems in dementia J Am Board Fam Med 25 2012 350 366
    • (2012) J Am Board Fam Med , vol.25 , pp. 350-366
    • Sadowsky, C.H.1    Galvin, J.E.2
  • 27
    • 84859598872 scopus 로고    scopus 로고
    • Biology of mitochondria in neurodegenerative diseases
    • L.J. Martin Biology of mitochondria in neurodegenerative diseases Prog Mol Biol Transl Sci 107 2012 355 415
    • (2012) Prog Mol Biol Transl Sci , vol.107 , pp. 355-415
    • Martin, L.J.1
  • 28
    • 84860151537 scopus 로고    scopus 로고
    • Impaired short-term plasticity in mossy fiber synapses caused by mitochondrial dysfunction of dentate granule cells is the earliest synaptic deficit in a mouse model of Alzheimer's disease
    • S.H. Lee, K.R. Kim, and S.Y. Ryu Impaired short-term plasticity in mossy fiber synapses caused by mitochondrial dysfunction of dentate granule cells is the earliest synaptic deficit in a mouse model of Alzheimer's disease J Neurosci 32 2012 5953 5963
    • (2012) J Neurosci , vol.32 , pp. 5953-5963
    • Lee, S.H.1    Kim, K.R.2    Ryu, S.Y.3
  • 29
    • 80051635037 scopus 로고    scopus 로고
    • Mitochondrial bioenergetics is defective in presymptomatic Tg2576 AD mice
    • M. Varghese, W. Zhao, and J. Wang Mitochondrial bioenergetics is defective in presymptomatic Tg2576 AD mice Transl Neurosci 2 2011 1 5
    • (2011) Transl Neurosci , vol.2 , pp. 1-5
    • Varghese, M.1    Zhao, W.2    Wang, J.3
  • 30
    • 70149093436 scopus 로고    scopus 로고
    • Mitochondrial bioenergetics deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
    • J. Yao, R.W. Irwin, L. Zhao, J. Nilsen, R.T. Hamilton, and R.D. Brinton Mitochondrial bioenergetics deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease Proc Natl Acad Sci USA 106 2009 14670 14675
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 14670-14675
    • Yao, J.1    Irwin, R.W.2    Zhao, L.3    Nilsen, J.4    Hamilton, R.T.5    Brinton, R.D.6
  • 31
    • 78650639655 scopus 로고    scopus 로고
    • Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE ε4 allele, the major late-onset Alzheimer's susceptibility gene
    • J. Valla, R. Yaari, and A.B. Wolf Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE ε4 allele, the major late-onset Alzheimer's susceptibility gene J Alzheimers Dis 22 2010 307 313
    • (2010) J Alzheimers Dis , vol.22 , pp. 307-313
    • Valla, J.1    Yaari, R.2    Wolf, A.B.3
  • 32
    • 69149109381 scopus 로고    scopus 로고
    • Greasing the wheels of Abeta clearance in Alzheimer's disease: The role of lipids and apolipoprotein e
    • J. Fan, J. Donkin, and C. Wellington Greasing the wheels of Abeta clearance in Alzheimer's disease: the role of lipids and apolipoprotein E Biofactors 35 2009 239 248
    • (2009) Biofactors , vol.35 , pp. 239-248
    • Fan, J.1    Donkin, J.2    Wellington, C.3
  • 33
    • 84855898777 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore provides a key to the diagnosis and treatment of traumatic brain injury
    • R.L. Veech, C.R. Valenti, and T.B. VanItallie The mitochondrial permeability transition pore provides a key to the diagnosis and treatment of traumatic brain injury IUBMB Life 64 2012 203 207
    • (2012) IUBMB Life , vol.64 , pp. 203-207
    • Veech, R.L.1    Valenti, C.R.2    Vanitallie, T.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.